Clinical trials: Headache Disorder
Migraine Disorders, Migraine, Classic
Understanding the Pathophysiology of Migraine Pain
Migraine is the most common headache disorder, prevalent in 18% of females and 6% of males. Emergency room visits, physician consults, hospitalizations, medications, and indirect costs such as lost work days and decreased…
- Conditions
- Migraine Disorders, Migraine, Classic, Migraine Without Aura
- Trial name
- NCT03026101
- Testing
- Nitroglycerin
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Montefiore Medical Center
Cervicogenic Headache
Effects of Garston Tool and Neuromuscular Reeducation in Cervical Headache
Patients suffering from Cervicogenic headache have restricted range of motion and pain which in turn causes functional disability and reduced quality of life.
- Trial name
- NCT05849545
- Testing
- Garston tool, Neuromuscular Re-education
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Health Education Research Foundation (HERF)
Migraine
Real-world Data Analysis of REN Treatment in Migraine Patients
Data analysis concerning four sets of metrics: A. Per-treatment patterns of REN use as a standalone treatment vs. in combination with medications. B.
- Trial name
- NCT04992897
- Testing
- Remote Electrical Neuromodulation (REN)
- Where
- 2 sites in United States, Israel
- Volunteers
- 12,151 people
- Sponsor
- Theranica
Low Back Pain, Migraine
Evaluating the Safety and Tolerability of OraVescent Fentanyl for Opioid Tolerant Patients With Noncancer Related Breakthrough Pain
The purpose of this study is to evaluate the safety and tolerability of OraVescent fentanyl for the potential treatment of breakthrough pain episodes in patients who have chronic noncancer pain.
- Conditions
- Low Back Pain, Migraine, Diabetic Neuropathies, Osteoarthritis
- Trial name
- NCT00228605
- Testing
- OraVescent Fentanyl
- Where
- 38 sites in United States
- Volunteers
- 500 people
- Sponsor
- Cephalon
Hearing Loss; Post-Dural Puncture Headache; Cesarean Delivery
Evaluation of Postoperative Hearing Loss After Spinal Anesthesia for Elective Cesarean Section in Pregnant Women
This prospective observational study will evaluate postoperative hearing changes in women undergoing elective cesarean delivery under spinal anesthesia.
- Trial name
- NCT07697651
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people
- Sponsor
- Duzce University
Migraine
Efficacy and Safety of BGG492 in the Treatment of Migraine
This study will assess the efficacy and safety of BGG492 used to treat migraine pain.
- Trial name
- NCT00892203
- Testing
- BGG492, Sumatriptan
- Where
- 13 sites in United States, Germany and 1 more
- Volunteers
- 75 people
- Sponsor
- Novartis
Migraine Headache
Examining the Efficacy of Kiko Exercises on the Prevention of Migraine Headaches
This pilot study hopes to show that after 3 months of Kiko training, Kiko naive patients with migraine will have a decrease in the frequency and severity of their migraines.
- Trial name
- NCT03651583
- Testing
- Kiko exercises-combines breathing and movement
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Regional Clinical Research
Post Dural Puncture Headache
Effect of Intravenous Oxytocin on Post Dural Puncture Headache After Caesarean Sections
Spinal anesthesia is the preferred anesthetic technique for cesarean section because of its advantages over epidural and general anesthesia.
- Trial name
- NCT07853924
- Testing
- oxytocin, Normal Saline
- Volunteers
- 100 people
- Sponsor
- Assiut University
Primary Headaches (Includes Migraines, Tension, Cluster Headaches)
Personalised Process-based Psychological Interventions for Paediatric Headaches
This project was an empirical single-case experimental design (SCED) study conducted as part of a DClinPsy doctoral thesis completed by one of the researchers.
- Trial name
- HEAD-FLEX (NCT07418723)
- Testing
- PBT Personalised
- Where
- United Kingdom
- Volunteers
- 5 people
- Sponsor
- Royal Holloway University
Postdural Puncture Headache
Greater Occipital Nerve Block Value in Management of Postdural Puncture Headache
Neuraxial techniques are well tolerated and effective options for labor analgesia and anesthesia for caesarean section, and may protect high risk women against severe maternal morbidity.
- Trial name
- NCT06380764
- Testing
- Greater Occipital Nerve Block, Bilateral suboccipital intramuscular injection, Epidural Blood Patch
- Where
- Egypt
- Volunteers
- 152 people
- Sponsor
- Benha University
Migraine, Pain
Nitrous Oxide for Acute Migraine Pain in the Emergency Room (ED)
BACKGROUND Migraine headaches account for 8-18% of all headaches seen in pediatric emergency rooms. Standard treatment includes IV pain medications, anti-emetics, and IV fluids.
- Trial name
- NCT01287052
- Testing
- Nitrous Oxide
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Nummular Headache, Migraine
Observational Prospective Study on the Presence of Typical Migraine Features in Nummular Headache Patients: The Numamig Study
Observational analytic study with prospective cohort design that aim to describe the presence of typical features of migraine in a cohort of nummular headache patients.
- Conditions
- Nummular Headache, Migraine, Headache Disorders, Primary
- Trial name
- NCT04299958
- Testing
- Patient diary
- Where
- Spain
- Volunteers
- 19 people
- Sponsor
- Hospital Clínico Universitario de Valladolid
Migraines
Quantitative Sensory Testing and Occipital Nerve Stimulator
The primary aim of this study is to assess the reversibility of a range of psychophysical markers of pain processing in patients with chronic migraine or cluster headache before and after ONS insertion and comparing to patients…
- Trial name
- NCT06022848
- Testing
- occipital nerve stimulator
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Barts & The London NHS Trust
Migraine
Clinical Effectiveness of Osteopathic Manipulative Treatment in Chronic Migraine
The aim of the present study is to determine the extend to which OMT is effective on a sample of subjects affected by migraine evaluated using the headache impact test (HIT-6) questionnaire.
- Trial name
- NCT01851148
- Testing
- osteopathic manipulative treatment, triptans
- Where
- Italy
- Volunteers
- 105 people
- Sponsor
- European Institute for Evidence Based Osteopathic Medicine
Primary Headache Disorder
Oxygen Therapy for Headache
Headache is one of the common causes of emergency department admissions and constitutes approximately 2%. Although the exact mechanism is not clear, It is known that high-flow oxygen therapy is effective in headache treatment.
- Trial name
- NCT05511155
- Testing
- Oxygen therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people
- Sponsor
- Aksaray University Training and Research Hospital
Acne, Bites
Implementation of a Minor Ailment Service in Community Pharmacy Practice
Self-care and self-medication are commonly the treatments of choice for the management of minor ailments. Minor ailments can be treated through community pharmacy using a Minor Ailment Service (MAS).
- Conditions
- Acne, Bites, Burns, Cold
- Trial name
- INDICA+PRO (NCT05247333)
- Testing
- Minor ailment service
- Where
- Spain
- Volunteers
- 20,987 people
- Sponsor
- Universidad de Granada
Migraine
Headache Diary for Migraine Patients
Use of a headache journal/calendar in patients who have migraine to ascertain if keeping a headache journal affects the quality of life and the headache burden.
- Trial name
- NCT07698249
- Testing
- Headache diary
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Hackensack Meridian Health
Migraine
Comparison of Wet Cupping and Acupuncture in Migraine
The aim of this study is to evaluate the effects of wet cupping therapy (WCT) on migraine patients and compare it with acupuncture. The patients will be randomized into three groups.
- Trial name
- NCT05282134
- Testing
- Wet cupping therapy, Acupuncture
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Karabuk University
Migraine With Aura
Endothelin-1 as a Potential Trigger of Migraine Aura
One third of migraine patients experience aura, i.e. dramatic, transient neurological symptoms, most often in the form of visual disturbances, that usually appear before the onset of migraine headache.
- Trial name
- NCT02906085
- Testing
- Endothelin-1
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Glostrup University Hospital, Copenhagen
Migraine Disorders
Occipital Nerve Stimulation (ONS) for Migraine: OPTIMISE
The primary objective of this study is to evaluate the safety and efficacy of occipital nerve stimulation (ONS) using the Boston Scientific Corporation (BSC) Precision™ System in the management of intractable chronic migraine…
- Trial name
- OPTIMISE (NCT01775735)
- Testing
- Occipital nerve stimulator
- Where
- 10 sites in United States
- Volunteers
- 28 people
- Sponsor
- Boston Scientific Corporation
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