Clinical trials: Headache Disorder
Cervicogenic Headache
The Effect of Myofascial Release in Patients With Cervicogenic Headache
Cervicogenic headache (CeH) is a secondary and often unilateral that is known by referring pain from soft or hard cervical structures to occipital, temporal, frontal and sometimes pre-orbital regions.
- Trial name
- RCT (NCT03113357)
- Testing
- Myofascial release technique, conventional exercise therapy
- Where
- Iran
- Volunteers
- 34 people
- Sponsor
- University of Social Welfare and Rehabilitation Science
Migraine Disorders
Pain Resilience and Holistic Health Care of Migraine
The purpose of this study is to investigate how pain resilience (as a personality characteristic or a strength) moderate the efficacy of treatment for patients with migraine.
- Trial name
- NCT04743492
- Testing
- cognitive behavioral therapy
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Changhua Christian Hospital
Refractory Migraine
Localized Injection of Lidocaine and Glucocorticoid for Headache Treatment Phase 1
The goal of this clinical trial is to test whether injecting lidocaine and steroids into two blood vessels of the brain can help treat chronic headaches (migraines).
- Trial name
- LIGHT 1 (NCT06462781)
- Testing
- Lidocaine hydrochloride, Methylprednisolone sodium succinate
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- The Cooper Health System
Migraine, Preventive Treatment
Prediction of Migraine Prevention Efficacy Based on Individual's Pain Modulation
A major reason for the substantial underuse of pharmacological prevention of migraine is its inadequate efficacy, since only ~50% of patients respond to a specific agent.
- Trial name
- NCT02101892
- Testing
- Amitriptyline
- Where
- Israel
- Volunteers
- 54 people
- Sponsor
- Rambam Health Care Campus
Migraine With Aura
Women With Migraine With Aura Neuroimaging Study
The purpose of this study is to investigate whether a particular form of migraine, migraine with aura, is associated with structural changes in the brain
- Trial name
- WOMAN (NCT02047695)
- Volunteers
- 345 people
- Sponsor
- Odense University Hospital
Postdural Puncture Headache
Spenopalatine Ganglion Block for Treatment of Post-dural Puncture Headaches
Postdural puncture headache (PDPH) is a severe, debilitating complication of dural puncture that can arise from insertion of an epidural or spinal needle for labour analgesia.
- Trial name
- SPGB (NCT04515901)
- Testing
- 2% lidocaine
- Where
- Canada
- Sponsor
- McMaster University
Subarachnoid Hemorrhage, Aneurysmal, Headache
Neuroinflammatory Response and Headache Control in Patients After Subarachnoid Hemorrhage
The purpose of this study is to determine the relationship between the Neuroinflammatory response and headache pain after subarachnoid hemorrhage.
- Conditions
- Subarachnoid Hemorrhage, Aneurysmal, Headache, Subarachnoid Hemorrhage
- Trial name
- HASH4-CSF (NCT03604276)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- MaineHealth
Migraine Headache
Integrating Acupuncture Into the Management of Migraines
This research is being done to study the effect of incorporating acupuncture into the management of migraines. The primary aim is to determine in a randomized, controlled study whether individuals experiencing migraines have…
- Trial name
- NCT01481103
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- National University of Health Sciences
Headache, Migraine, Chronic Migraine Headache
Stellate Ganglion Blockade for Refractory Chronic Migraine
Stellate Ganglion Block (SGB) is an interventional anesthetic technique used to treat pain conditions affecting the head, face, neck, and upper extremities by temporarily blocking sympathetic nerve output.
- Trial name
- SGB-RCM (NCT06891118)
- Testing
- Procedure/Surgery: Ultrasound-Guided Stellate Ganglion Block
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Ankara City Hospital Bilkent
Post-Traumatic Headache, Concussion, Mild
Clinical Characteristics and Pathophysiology of Post-Traumatic Headache
To better understand the clinical characteristics and complex pathophysiological events that constitute persistent post-traumatic headache (PPTH) and to identify possible calcitonin gene-related peptide (CGRP) hypersensitivity in…
- Trial name
- NCT03791515
- Testing
- Calcitonin Gene-Related Peptide
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Aneurysmal Subarachnoid Hemorrhage, Headache
SubArachnoid Hemorrhage HEadache Treated by Lumbar Puncture
Headache control is one of the major challenges in patients who suffered an acute aneurysmal subarachnoid hemorrhage (aSAH). Headache affects 90% of the patient and is resistant to the major pain medication.
- Trial name
- SAH-HELP (NCT03754335)
- Testing
- Lumbar puncture
- Where
- France
- Volunteers
- 74 people
- Sponsor
- University Hospital, Toulouse
Headache Disorders, Tension-Type Headache
An Open Internet-based Survey and Natural Language Processing Project Analysing Written Monologues by Headache Patients
Headache disorders are among the most prevalent medical conditions worldwide. The diagnosis of headache disorders is based on medical history taking.
- Conditions
- Headache Disorders, Tension-Type Headache, Migraine Disorders, Cluster Headache
- Trial name
- NLPH-OPEN (NCT05153876)
- Testing
- Questionnaires
- Where
- Belgium
- Volunteers
- 1,150 people
- Sponsor
- University Hospital, Ghent
Migraine
Standardized sTudy With Almotriptan in eaRly Treatment of Migraine
This is a observational, open, prospective, single arm cohort study within authorized SPC conditions to describe the effectiveness of Almotriptan in treating acute migraine attacks when pain is mild and in the first hour of pain…
- Trial name
- START (NCT00725140)
- Where
- 3 sites in France, Italy and 1 more
- Volunteers
- 501 people
- Sponsor
- Almirall, S.A.
Migraine Without Aura, Unilateral Headache
Acupuncture for Migraine Prophylaxis
Hypothesis: Acupuncture obtains an abiding effect on migraine prophylaxis Design: A open-label randomized controlled trial. 249 participants will be included.
- Trial name
- AMP (NCT01687660)
- Testing
- acupuncture
- Where
- China
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Li ying
Headache, Migraine Without Aura
Effect of Ivabradine on Levcromakalim-Induced Symptoms in Individuals With Migraine Without Aura (ILIM)
This study aims to explore the effect of Ivabradine on Levcromakalim-induced migraine in individuals with migraine without aura.
- Trial name
- ILIM (NCT04853797)
- Testing
- Levcromakalim, Ivabradine
- Where
- 2 sites in Denmark
- Volunteers
- 37 people
- Sponsor
- Danish Headache Center
Post-Dural Puncture Headache
Effectiveness of Nebulized Dexmedetomidine for Treatment of Obstetric Post-Dural Puncture Headache
Postdural puncture headache (PDPH) is a common complication, following neuraxial techniques. The obstetric population is particularly prone to PDPH. Therefore, treatment of PDPH is a key issue in obstetric anesthesia.
- Trial name
- NCT04327726
- Testing
- Dexmedetomidine Nebulization, 0.9% Saline Nebulization
- Where
- Egypt
- Volunteers
- 43 people
- Sponsor
- Zagazig University
Migraine
Efficacy and Safety of Eletriptan for the Treatment of Migraine in Patients Not Satisfied With Rizatriptan Therapy
To assess the efficacy and safety of eletriptan for migraine headaches in subjects who were not satisfied with rizatriptan therapy
- Trial name
- NCT00632385
- Testing
- Eletriptan
- Where
- 16 sites in United States
- Volunteers
- 127 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Migraine Headache
Low- Dose Propofol Infusion as an Abortive Treatment for Migraine Headaches in Pediatric Patients
Propofol has been used in adult populations to treat migraines as an abortive agent. Investigators plan to investigate its efficacy as an abortive agent in the pediatric population when administered as a safe low-dose infusion.
- Trial name
- Propofol2014 (NCT02485418)
- Testing
- Propofol
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Texas Southwestern Medical Center
Headache, Tension-Type Headache
Instrument-assisted Soft Tissue Mobilization and Phonophoresis on Trigger Points of Tension Headache
General purpose: It was investigate the effect of IASTM and phonophoresis on Tension Type headache. Specific Purpose: 1. It was investigate the effect of IASTM on headache frequency, PPT, pain intensity, and functional disability…
- Trial name
- NCT04950413
- Testing
- Conventional physical therapy program, IASTM by M2t blade, Phonophoresis
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nada Gamal Saad
Migraine, Depression
Treatment for Migraine and Mood (Team-M)
The researchers propose a two-arm pilot study of telephone and video delivered Mindfulness-based Cognitive Therapy (MBCT-T and MBCT-V) in people with migraine and depressive symptoms.
- Trial name
- TEAM-M (NCT04992494)
- Testing
- MBCT-Telephone, MBCT-Video
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- NYU Langone Health
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