Clinical trials: Headache Disorder
Migraine Disorders
An Open-label, Randomized, 3-period Crossover Study to Evaluate Sumatriptan Pharmacokinetics for a TREXIMA™ (Sumatriptan Succinate / Naproxen Sodium) Tablet Followed by IMITREX® (Sumatriptan Succinate)
This study will evaluate the exposure of sumatriptan after administration of TREXIMA (sumatriptan 85mg/naproxen sodium 500mg) followed by a subcutaneous IMITREX injection (4mg or 6mg) 2 hours later compared to administration of a…
- Trial name
- NCT00875784
- Testing
- TREXIMA™, IMITREX® (4mg), IMITREX® (6mg)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Migraine
Comparison of Occipital Nerve and Sphenopalatine Ganglion Blockade
Migraine is a chronic disorder that causes disability. Episodic migraine can be managed by prophylactic medical treatment or interventional pain procedures.
- Trial name
- NCT06243874
- Testing
- greater occipital nerve block, transnasal sphenopalatine ganglion block
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ankara University
Headache, Migraine
Hemodynamic and Headache-Inducing Effect of Intravenous Vasoactive Intestinal Peptide in Migraineurs
We hypothesized that infusion of VIP may induce headache/migraine in migraineurs and that VIP-induced headache may be associated with dilation of intra- and extracranial vessels.
- Conditions
- Headache, Migraine, Vasoactive Intestinal Peptide, Ultrasonography, Doppler, Transcranial
- Trial name
- NCT00272896
- Testing
- Vasoactive intestinal peptide
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Danish Headache Center
Chronic Migraine
Non-Invasive Neurostimulation for the Prevention of Chronic Migraine
The purpose of this multi-center, prospective, double-blind, randomized, sham-controlled pilot study is to study feasibility and collect preliminary clinical data related to the safety and clinical benefits of daily use of…
- Trial name
- NCT01667250
- Testing
- GammaCore Active Device
- Where
- 6 sites in United States
- Volunteers
- 59 people
- Sponsor
- ElectroCore INC
Patent Foramen Ovale
Precutaneous High Risk Patent Foramen Ovale to Treat Migraine Headaches
The foramen ovale, a kind of physiologic channel in the interatrial septum in the heart at embryonic stage, is closed normally at 5-7 months after birth.
- Trial name
- NCT02777359
- Testing
- the transcatheter closure of PFO
- Where
- China
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Chronic and Episodic Headache, Headache Disorders
PERSONOLOGICAL STRUCTURE, COGNITIVE FUNCTIONS AND CENTRAL SENSITIZATION IN HEADACHE
Headache, in its episodic and chronic forms, cannot be considered solely as an isolated neurological symptom, but as a complex condition of a bio-psycho-social nature.
- Trial name
- AURA (NCT07268768)
- Testing
- Neuropsychological assessment
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Migraine With Aura, Migraine Without Aura
Preventive Treatment of Episodic and Chronic Migraine
This is an open label pilot study to determine whether milnacipran can reduce headache frequency in episodic and chronic migraine sufferers.
- Conditions
- Migraine With Aura, Migraine Without Aura, Chronic Migraine
- Trial name
- NCT01319825
- Testing
- milnacipran
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- California Medical Clinic for Headache
Cervicogenic Headache
Cervicogenic Headache, Cognitive Dysfunction
The goal of this study was to determine the frequency of cognitive dysfunction in patients with cervicogenic headache. participants will be asked questions to determine their cognitive status at once.
- Trial name
- NCT05572489
- Testing
- visual pain scale Beck depression scale Pain catastrophizing scale Short Form-36 Standard Mini mental test Montreal cognitive assessment scale
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Konya Beyhekim Training and Research Hospital
Pain, Chronic, Migraine Disorders
Progressive Relaxation Training Effect On Pain, Activity And Social Participation In Women With Tension-Type Headache And Migraine
Objective: The aim of this study was to investigate and compare the effects of PRT on pain characteristics, attack frequency, activity self-efficacy perception, and social participation in women with two different types of…
- Conditions
- Pain, Chronic, Migraine Disorders, Tension-Type Headache
- Trial name
- NCT06050382
- Testing
- PROGRESSIVE RELAXATION TRAINING
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Hacettepe University
Migraine Headache
Comparative Study Between Valproate and Memantine in the Prophylactic Management of Episodic Migraine.
Migraine is one of the three most disabling diseases worldwide. Constituted by recurrent episodes of headache, characterized by unilateral location, throbbing character, moderate or severe intensity, worsening with physical…
- Trial name
- NCT04698525
- Testing
- Valproate Sodium, Memantine
- Where
- Mexico
- Volunteers
- 33 people
- Sponsor
- Universidad Autonoma de San Luis Potosí
Migraine
Observational Study on the Efficacy, Safety, and Tolerability of GAlcanezumab in Real Life Migraine Patients in ITaly
Objective: To determine in real life the efficacy, safety and tolerability of galcanezumab in the prevention of high-frequency episodic migraine (HFEM) and chronic (CM) migraine.
- Trial name
- GARLIT (NCT04803513)
- Testing
- Galcanezumab
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Campus Bio-Medico University
Dizziness, Cervicogenic Headache
Comparing the Effects of Sub-Occipital Myofascial Release With and Without SNAG on People With Cervicogenic Dizziness.
Cervicogenic dizziness is defined as a sensation of rotation, resulting from an alteration of the neck proprioceptive afferents of the upper cervical spine.Sub-occipital Release, a type of Myofascial Release (MFR) is a form of…
- Trial name
- NCT07062809
- Testing
- Sub Occipital Myofascial release and (SNAGS)., Sub Occipital Myofascial release.
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Migraine
MRI Outcomes of Mindfulness Meditation for Migraine
112 migraine subjects will be initially randomly assigned to Mindfulness-Based Stress Reduction (MBSR) or a Stress Management for Headache group (SMH).
- Trial name
- NCT02133209
- Testing
- Mindfulness Based Stress Reduction, Stress Management for Headaches
- Where
- 2 sites in United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cervicogenic Headache
Therapeutic Efficacy of Different Wavelengths of Low-Level Laser Therapy in the Treatment of Cervicogenic Headache
This study tests if low-level laser therapy (LLLT) with different light wavelengths can help people with cervicogenic headache, a type of headache caused by neck problems.
- Trial name
- WELL (NCT07163208)
- Testing
- Low-Level Laser Therapy (LLLT), Routine Physical Therapy (RPT)
- Where
- Pakistan
- Volunteers
- 150 people
- Sponsor
- University of Lahore
Tinnitus
Physiotherapeutic Approach to Tinnitus
Intervention experiments in the physiotherapeutic field targeted diagnostics and therapy of tinnitus. The goal is to find various groups of tinnitus patients and an ideal therapeutic approach between physical therapy means…
- Trial name
- NCT05667168
- Testing
- physiotherapy approach
- Where
- Czechia
- Volunteers
- 400 people
- Sponsor
- Charles University, Czech Republic
Vertigo, Vertigo, Peripheral
Effectiveness of Gaze Stability Exercises on Balance and Activities of Daily Living Among Patients Suffering Vertigo With Vestibular Neuritis in Saudi Arabia
Gaze stability exercise is a medical procedure for persons with unilateral vestibular disturbances such as vestibular neuritis or persons who have had tumors of their 8th nerve.
- Conditions
- Vertigo, Vertigo, Peripheral, Vertigo Labyrinthine, Migraine
- Trial name
- NCT04842474
- Testing
- Gaze stability exercises and balance exercises
- Where
- Saudi Arabia
- Volunteers
- 20 people
- Sponsor
- King Saud University
Migraine Disorders, Brain
Audition After a Lesion and in Migraine. (AuditionPostLesion)
The project studies auditory processing after brain damage (in temporal and/or frontal areas) and in migraine. The auditory processes investigated are attention, short-term memory, sound-induced emotions.
- Trial name
- NCT02791997
- Testing
- Neuropsychological tests, Neurophysiological tests
- Where
- 2 sites in France
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
New Daily Persistent Headache (NDPH), New Daily Persistent Headache
New Daily Persistent Headache Survey
Purpose: to explore headache characteristics and treatment effects of patient with new daily persistent headache (NDPH) through an online survey. Research design: Online survey of patients with new daily persistent headache.
- Trial name
- NDPH (NCT05984719)
- Where
- United States
- Volunteers
- 803 people
- Sponsor
- The University of Texas Health Science Center, Houston
Healthy, Migraine
Neuropeptides in the Humane Intra- og Extracerebral Circulation.
The study aim at examining whether Sumatriptan changes the plasma values of the neuropeptides vasoactive intestinal polypeptide (VIP), calcitonin gene-related peptide (CGRP) and pituitary adenylate cyclase activating peptide…
- Trial name
- NCT00399633
- Testing
- sumatriptan
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Tension Type Headache
Desvenlafaxine for Preventive Treatment of Frequent Episodic Tension-type Headache
To evaluate whether Desvenlafaxine can reduce the frequency and severity of TTH attacks in patients.
- Trial name
- NCT07359248
- Testing
- Desvenlafaxine
- Where
- China
- Volunteers
- 432 people
- Sponsor
- Tongji Hospital
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