Clinical trials: Headache Disorder
Migraine
The Effects of Transcutaneous Occipital Nerve Stimulation and Instrument-Assisted Soft Tissue Mobilization on Patients With Chronic Migraine
In this study, it was aimed to examine the effects of two different treatments applied to the neck region, which have been popular in recent years, on migraine.The study included 45 female patients aged 20-50 years with migraine…
- Trial name
- NCT05372796
- Testing
- IASTM, home exercise, Chattanooga direct Tens device (DJO UK Ltd, Guildford Surrey, United Kingdom)
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Emine Atıcı
Migraine
Inflammatory Markers in Patients With Active Migraine Headaches
The purpose of this study is to determine whether C-Reactive Protein (CRP) is elevated in patients with active migraine headaches.
- Trial name
- NCT00471861
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Westside Family Medical Center, P.C.
Migraine Disorders, Medication Overuse Headache
Greater Occipital Nerve Block for Migraine With Medication Overuse Headache
Migraine is among the leading causes of disability worldwide. Inappropriate use of acute medications in the setting of primary headache, particularly migraine can result in a debilitating condition known as medication overuse…
- Conditions
- Migraine Disorders, Medication Overuse Headache, Greater Occipital Nerve Block
- Trial name
- GONB_MOH (NCT07568496)
- Testing
- Lidocaine 2% and Methylprednisolone 80 mg
- Where
- 3 sites in Thailand
- Volunteers
- 130 people
- Sponsor
- Mahidol University
Cervicogenic Headache
CORRELATION BETWEEN FORWARD HEAD POSTURE, CERVICAL MUSCLES ENDURANCE, AND PROPRIOCEPTIVE FUCTIONS IN CERVICOGENIC HEADACHE AMONG LATE ADOLESCENT STUDENTS.
Forward Head Posture (FHP) is a common postural deviation characterized by anterior translation of the head relative to the trunk, which increases load on cervical muscles and joints.
- Trial name
- NCT07763886
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Delta University for Science and Technology
Migraine
Telcagepant for Prevention of Menstrually Related Migraine in Female Participants With Episodic Migraine (MK-0974-065)
This is a multicenter study to test the hypothesis that telcagepant is superior to placebo in preventing perimenstrual migraines as measured by mean monthly headaches during the entire treatment period.
- Trial name
- NCT01125774
- Testing
- Telcagepant
- Volunteers
- 4,548 people
- Sponsor
- Merck Sharp & Dohme LLC
Migraine
Melatonin for Adolescent Migraine Prevention Study
This will be a randomized, multi-site double-blind placebo-controlled trial of melatonin (2 different dosing arms) vs. placebo for migraine prevention in adolescents.
- Trial name
- MAP (NCT03150797)
- Testing
- Melatonin
- Where
- 2 sites in United States
- Volunteers
- 72 people
- Sponsor
- Amy Gelfand
Migraine
Effect of Acetyl-L-carnitine in Migraine
Traditionally, beta blockers have been used for migraine prophylaxis, but in later years also antiepileptic drugs. Contraindications and side effects have to some degree limited their use, and new prophylactics that can be used…
- Trial name
- ALCAR (NCT01695317)
- Testing
- Acetyl-L-carnitine
- Where
- Norway
- Volunteers
- 72 people
- Sponsor
- Norwegian University of Science and Technology
Headache, Tension-Type Headache
Instrument-assisted Soft Tissue Mobilization and Phonophoresis on Trigger Points of Tension Headache
General purpose: It was investigate the effect of IASTM and phonophoresis on Tension Type headache. Specific Purpose: 1. It was investigate the effect of IASTM on headache frequency, PPT, pain intensity, and functional disability…
- Trial name
- NCT04950413
- Testing
- Conventional physical therapy program, IASTM by M2t blade, Phonophoresis
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nada Gamal Saad
Migraine
A Dual Intervention in Migraine Treatment: Tens and Exercise
The aim of this clinical trial was to investigate the effects of TENS and exercise training on pain and disability in women diagnosed with migraine.
- Trial name
- NCT07125820
- Testing
- Experimental Group, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Suleyman Demirel University
Migraine
A Study of Gastrointestinal Emptying Time in Adult Participants With Migraine Before and After Start of a mAb CGRP Antagonist
The purpose of this study is to measure the gastrointestinal emptying time using the wireless motility capsule (WMC) technology (FDA approved SmartPill™) in adult participants with migraine who are taking a monoclonal antibody…
- Trial name
- NCT04294147
- Testing
- Galcanezumab, Erenumab
- Where
- 3 sites in United States
- Volunteers
- 65 people
- Sponsor
- Eli Lilly and Company
Migraine Headache, With or Without Aura
Staccato Prochlorperazine in Migraine (in Clinic)
Development of Staccato Prochlorperazine for the treatment of migraine headache.
- Trial name
- NCT00610428
- Testing
- Staccato Prochlorperazine 5 mg, Staccato Prochlorperazine 10 mg
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Alexza Pharmaceuticals, Inc.
TBI (Traumatic Brain Injury)
Improving Functions in MTBI Patients With Headache by rTMS
Due to recent wars in Afghanistan and Iraq, the number of Veteran suffering from Mild traumatic brain(MTBI) injury and PTSD increases rapidly.
- Trial name
- NCT01948947
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- VA Office of Research and Development
Migraine
Real World Effectiveness of Eptinezumab in Participants With Migraine
The purpose of this study is to examine how eptinezumab compares to other advanced preventive medications in a real-world community setting in adult participants with episodic migraine (EM) or chronic migraine (CM).
- Trial name
- EVEC (NCT05284019)
- Testing
- Eptinezumab, Erenumab, Onabotulinumtoxin-A
- Where
- 10 sites in United States
- Volunteers
- 32 people
- Sponsor
- H. Lundbeck A/S
Chronic Tension-Type Headache, Episodic Tension-Type Headache
Treatment of Tension Headache Using Soft Tissue Techniques VS Vagus Stimulation Techniques.
A treatment based on manual therapy and vagus nerve stimulation is more effective than manual therapy only to reduce frequency, intensity and pressure pain threshold in patients with tension type headache.
- Trial name
- NCT05097300
- Testing
- Suboccipital inhibition, Ischemic pressure, Passive stretching
- Where
- 2 sites in Spain
- Volunteers
- 42 people
- Sponsor
- Lucia Trullenque Espallargas
Tension-Type Headache
Effcet of Temporomandibular Joint Disorder Relaxation and Myofacial Relaxation Techniques on Tension Headache
The aim of this course is to investigate the effect of temporomandibular joint relaxation and myofacial relaxation techniques on quality of life , Joint range of motion, headache, depression in individuals with tension type…
- Trial name
- NCT05058573
- Testing
- Control group (n=22)
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Alanya Alaaddin Keykubat University
Migraine
A Comparison of the Efficacy and Safety of Topiramate Versus Placebo in Preventing Migraine Headaches in Children
The purpose of this study is to assess the safety and efficacy of topiramate as compared to placebo in preventing migraines in children.
- Trial name
- NCT00237302
- Testing
- topiramate
- Volunteers
- 162 people
- Sponsor
- Ortho-McNeil Neurologics, Inc.
Migraine According to International Headache Society (IHS) Criteria (ICHD-II)
A Randomized, Parallel, Double-blind, Placebo-controlled Study of Vitamin D as Prophylactic Treatment for Migraine
The trial is primarily designed to investigate whether treatment with vitamin D may influence migraine in a placebo-controlled, blinded study. The hypothesis is that vitamin D may serve as a prophylactic treatment of migraine.
- Trial name
- NCT01695460
- Testing
- D3 Vitamin ®
- Where
- 2 sites in Denmark
- Volunteers
- 48 people
- Sponsor
- Aalborg University
Medication Overuse Headache
Intravenous Treatments Used in Medication Overuse Headache Bridge Treatment
Medication overuse headache is the chronicity of headaches, which occurs more than 15 days a month, as a result of frequent use of painkillers, opioids or migraine attack drugs (ergotamine, triptan) in individuals with…
- Trial name
- NCT05608642
- Testing
- Intravenous hydration, Intravenous prednisolone, Intravenous lidocaine
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Diskapi Teaching and Research Hospital
Migraine
An Open-label, Intermediate Size, Expanded Access Study of BHV-3000 in the Acute Treatment of Migraine
The purpose of this protocol is to allow subjects who completed any BHV3000 (rimegepant) clinical study to continue to have access to rimegepant while collecting ongoing safety data.
- Trial name
- NCT03934086
- Testing
- rimegepant
- Sponsor
- Pfizer
Migraine Disorders, Patent Foramen Ovale
Effects of PFO Closure on Glymphatic Function and Clinical Symptoms in Patients With Migraine
Patent Foramen Ovale (PFO) is a common congenital heart defect. Recent studies have suggested a potential association between PFO and migraines, particularly migraine with aura.
- Conditions
- Migraine Disorders, Patent Foramen Ovale, Right-to-Left Shunt, Cardiac
- Trial name
- NCT07170176
- Testing
- Percutaneous Patent Foramen Ovale Closure, No Intervention
- Where
- 2 sites in China
- Volunteers
- 150 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
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