Clinical trials: Healing
Chronic Otitis Media Tympanic Membrane Perforation
Effect of Platelet-Rich Plasma on Eardrum Healing and Hearing After Tympanoplasty in Adults
This single-center controlled trial evaluated whether intraoperative application of autologous platelet-rich plasma (PRP)-impregnated absorbable gelatin sponge improves graft take rates and audiological outcomes in adults…
- Trial name
- NCT07664319
- Testing
- Autologous platelet-rich plasma (PRP)-impregnated Spongostan, Dry Spongostan (absorbable gelatin sponge)
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ebubekir Toprak
Periodontitis
The Effect of Locally Delivered Ciclosporin as an Adjunct to Healing After Treatment of Periodontal Pockets
The main purpose of the trial is to investigate the effect of locally delivered ciclosporin as an adjunct to non-surgical mechanical debridement in the treatment of chronic periodontitis and to compare it to mechanical…
- Trial name
- NCT02366585
- Testing
- Ciclosporin
- Where
- Sweden
- Volunteers
- 23 people
- Sponsor
- PerioC Limited
Skin Cancer, Basal Cell Carcinoma
Autologous Patch Healing vs. Secondary Intention Healing After Mohs Micrographic Surgery
The primary objects of this study is to explore the potential effect of the autologous patch to optimize wound healing after skin cancer surgery with Mohs micrographic surgery (MMS) in the face in a randomized controlled trial…
- Trial name
- NCT05170035
- Testing
- MMS + Autologous patch, MMS and secondary intention healing
- Where
- Denmark
- Volunteers
- 26 people
- Sponsor
- Bispebjerg Hospital
Cesarean Section, Surgical Wound
To Explore the Effectiveness and Feasibility of HERADERM Hydrogel Wound Dressing on Caesarean Section Surgical Site
The wound of cesarean section involves multiple layers of tissue and often cause significant postoperative pain. The epidermal wound typically heals within 1 to 2 weeks after surgery.
- Conditions
- Cesarean Section, Surgical Wound, Surgical Wound Infection, Wounds and Injuries
- Trial name
- NCT06558240
- Testing
- HERADERM Hydrogel Wound Dressing (Sterile)
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Rotator Cuff Tear
Post-op Rehabilitation's Influence on Tendon Healing & Clinical Outcomes Following Arthroscopic Rotator Cuff Repair
The purpose of this study is to better understand the influence of post-operative rehabilitation on the rate of tendon healing and clinical outcomes following arthroscopic repair of the rotator cuff.
- Trial name
- NCT00756015
- Testing
- Early Motion Protocol, Immobilization
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Washington University School of Medicine
Arthroplasty, Replacement, Shoulder
Evaluation of Regeneten Augmentation for Subscapularis Healing After Total Shoulder Arthroplasty (RESTOR)
The purpose of this study is to evaluate whether augmentation of subscapularis repair with the Regeneten implant after anatomic total shoulder arthroplasty (TSA) can improve rates of subscapularis healing and improve clinical…
- Trial name
- NCT04861714
- Testing
- Regeneten, Standard repair
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Ohio State University
Apical Periodontitis, Periapical Lesion
Evaluation of the Effect of Leukocyte and Platelet-rich Fibrin on Healing After Periradicular Surgery
The aim of this study is to evaluate the effect of two different periapical surgery methods ("curettage+apical resection" and "curettage") on the bone regeneration and clinical healing without applying any material or with…
- Trial name
- NCT05847647
- Testing
- Retrograde Filling Group, Retrograde Filling+L-PRF Group, (Orthograde Filling Group / OG Group).
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Seyda Ersahan, DDS, PhD
Androgenetic Alopecia, Wound Healing
Topical Rifamycin SV for Wound Healing After Sapphire FUE Hair Transplantation
This prospective, parallel-group controlled clinical study evaluated whether a single topical rifamycin SV protocol added to standardized care after sapphire follicular unit extraction (FUE) was associated with earlier recorded…
- Trial name
- NCT07155408
- Testing
- Povidone-Iodine 10%, Rifamycin SV Sodium
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Elif Asena KANTARCI
Erosive Esophagitis
Impact of Timing on the Efficacy of Zegerid 40 mg in Healing Reflux Esophagitis: A Pilot Study
The purpose of this study was to determine the effect of morning versus bedtime administration of omeprazole/sodium bicarbonate (Zegerid) on endoscopic healing for patients with moderate or severe reflux esophagitis.
- Trial name
- NCT00693225
- Testing
- Omeprazole/sodium bicarbonate
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Yvonne Romero
Chronic Ulcers: Non-healing Deep Cavity Wounds (e.g., Diabetic Foot Ulcers, Arterial Ulcers, Post-surgical Wound Healing Disorders)
INJECTHEAL - Investigation of Chronic Wound Exudate and Biofilm
This prospective observational study will collect routine clinical waste material from 72 adults with chronic, non-healing wounds, including wound exudate from negative pressure therapy containers or sponges and wound…
- Trial name
- INJECTHEAL (NCT07745764)
- Testing
- standard of care
- Where
- Germany
- Volunteers
- 72 people
- Sponsor
- Barbara Wolff-Winiski
Wound Healing Disturbance of
HIP-STITCH (Wound Recovery After THA)
This prospective randomised trial will investigate the effect of four different suturing techniques (Monocryl, Vicryl Rapide with Indermil skin glue, Dermabond Prineo, and Stryker Zip) on the amount of aberrant wound recovery…
- Trial name
- NCT06275776
- Testing
- Ethicon Monocryl Smooth Suture, Ethicon Vicryl Rapide Braided Suture, Flexifuze Indermil Topical Skin Adhesive
- Where
- Netherlands
- Volunteers
- 236 people
- Sponsor
- Reinier Haga Orthopedisch Centrum
Complete Edentulism Due to Periodontal Disease (Disorder)
Post Extraction Wound Healing Evaluation of Immediate Complete Denture Using IPR Scale
In the first part, after a brief introduction, the advantages and disadvantages of immediate dentures are compared. There is a detailed discussion on assessment and treatment planning which includes history taking, examination of…
- Trial name
- NCT05464914
- Testing
- CEO Pack
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Badr University
Pressure Ulcer, Diabetic Foot Ulcer
Efficacy of Wound Dressings With Copper Oxide
Thirty patients of 18-85 years of age, with 2-30 cm2 pressure ulcers or post-op wounds, will be recruited and treated with either wound dressing containing silver or wound dressings containing copper oxide microparticles.
- Trial name
- NCT04634838
- Testing
- MedCu Antibacterial Wound Dressings with Copper Oxide
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- MedCu Technologies Ltd.
Burns
Dermal Substitute and Topical Negative Pressure in Burns
The purpose of this study is to determine whether a treatment of full thickness wounds by the dermal substitute Matriderm, split skin graft and VAC treatment will improve scar quality, demonstrated by a significant increase of…
- Trial name
- VAC-M (NCT00548314)
- Testing
- dermal matrix, Split skin graft, VAC therapy (KCI)
- Where
- Netherlands
- Volunteers
- 86 people
- Sponsor
- Association of Dutch Burn Centres
Knee Osteoarthritis, Hip Osteoarthritis
Comparison of Knotless Barbed Suture and Standard Suture in Knee Replacement Patients
Barbed suture use has been gaining increased acceptance and has been reported to offer potential advantages in wound closure of hip and knee replacement surgeries.
- Trial name
- NCT03031314
- Testing
- barbed suture, standard suture
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Washington Hospital Healthcare System
Alveolar Ridge Preservation, Bone Regeneration
Using Different Biomaterials to Preserve Bone After Tooth Extraction
This four-arm randomized controlled clinical trial evaluated the clinical, radiographic, and histological outcomes of different approaches to alveolar ridge preservation following tooth extraction.
- Conditions
- Alveolar Ridge Preservation, Bone Regeneration, Tooth Extraction, Dental Implants
- Trial name
- NCT07394738
- Testing
- Allograft, Autogenous Dentin Graft, Hyaluronic Acid Gel
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Inonu University
Alveolar Ridge Preservation, Socket Preservation
Radiographic And Histomorphometric Assessment Following Alveolar Ridge Preservation Using Chitosan Gel Versus Normal Socket Healing In Posterior Maxillary and Mandibular Region
After tooth extraction, the alveolar bone, which supports the teeth, undergoes a natural resorption process. This bone loss can be significant, especially in the first few months post-extraction, leading to a reduction in both…
- Conditions
- Alveolar Ridge Preservation, Socket Preservation, Wound Healing
- Trial name
- NCT07571863
- Testing
- Chitosan gel Sigma-Aldrich® in socket preservation, Gelfoam® absorbable gelatin sponge in socket preservation post extraction
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Cairo University
Leg Ulcer
Research of Prognostic Factors Associated With Healing of Venous Leg Ulcers
This study was undertaken to identify prospectively which clinical venous leg ulcer (VLU) characteristics known as possible prognostic markers, and which sociodemographic and psychologic factors associated with VLU are associated…
- Trial name
- NCT01673412
- Testing
- Psychological tests
- Where
- 35 sites in France
- Volunteers
- 104 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Wound Healing Disorder
Photobiomodulation With Polarized Light as Adjunctive Treatment in Diabetic Foot Ulcer
Effect of Photobiomodulation With Polarized Light on wound healing and aerobic microflora in Diabetic Foot Ulcer
- Trial name
- NCT04446767
- Testing
- polarized light, Medical Care
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Surgical Wound Infection
Effects of a New Antimicrobial Dressing on Wound Healing and Incidence of Sternal Wound Infections
The primary objective of this pivotal study is to determine if a new antimicrobial dressing, applied to the sternal incisions of cardiac surgical subjects, will demonstrate a decreased cumulative incidence rate(CI) of localized…
- Trial name
- NCT00203541
- Testing
- TELFA™ A.M.D. Island dressing
- Where
- United States
- Volunteers
- 1,100 people
- Sponsor
- Tyco Healthcare Group