Clinical trials: Healing Surgical Wounds
Surgical Wound
PICO 7 vs PICO 14 in Revision Hip and Revision Knee Surgery.
This is a single-site trial, and it has been designed to compare a revision hip cohort with a revision knee cohort. All consecutive eligible patients, under the care of participating Co-Investigator Orthopaedic Surgeons, are…
- Trial name
- NCT05389410
- Testing
- PICO 7, PICO 14
- Where
- United Kingdom
- Volunteers
- 164 people
- Sponsor
- Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
Wounds and Injuries, Wound Infection
Long Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wounds and Injuries, Wound Infection, Facial Bones Fracture, Soft Tissue Injuries
- Trial name
- FTFDT2 (NCT03880188)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Healthy, Macromastia
NPWT Reduction Mammaplasty
In this prospective, randomized, split-body control trial, we aim to compare complications, patient-reported outcomes, and cost differentials following reduction mammaplasty with prophylactic closed incision negative pressure…
- Conditions
- Healthy, Macromastia, Negative Pressure Therapy, Mammaplasty
- Trial name
- NCT06725459
- Testing
- Prophylactic ciNPWT, Standard Adhesive Dressing
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Medstar Health Research Institute
Postoperative Abdominal Wounds, Wound-healing Impairments
Evaluate the Efficacy of the Treatment of Iatrogenic Subcutaneous Abdominal Wounds (ISAW) After Surgery by Application of Negative Pressure Wound Therapy (NPWT) in Comparison to Standard Conventional Wound Therapy (SCWT) of the Clinical Routine
The purpose of this study is to determine whether Negative Pressure Wound Therapy (NPWT) or Standard Conventional Wound Therapy (SCWT) are effective in the treatment of Iatrogenic Subcutaneous Abdominal Wound healing-impairments…
- Trial name
- ISAW (NCT01611207)
- Testing
- Negative Pressure Wound Therapy, Standard Wound Therapy
- Where
- 34 sites in Germany
- Volunteers
- 12 people
- Sponsor
- University of Witten/Herdecke
Evaluate to Effects of Two Antiseptic Products and Showering
CHLORHEXIDINE GLUCONATE AND POVIDONE IODINE
The study was planned to evaluate the effects of two most commonly used antiseptic products and showering on the healing process, such as wound healing and postoperative maternal comfort in cesarean section.
- Trial name
- NCT05953714
- Testing
- incision side cleaning with antiseptic products
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Sakarya University
Thyroid Diseases, Wound Healing
Safety and Efficacy of NTP in Thyroid Surgery: Pilot Study on Morbidity Prevention and Adjuvant Oncological Control
The goal of this clinical trial is to evaluate the therapeutic efficacy and safety of non-thermal plasma (NTP) as an adjuvant treatment for surgical bed decontamination and accelerated tissue repair in patients undergoing total…
- Conditions
- Thyroid Diseases, Wound Healing, Thyroidectomy, Surgical Wound Infection
- Trial name
- NCT07382973
- Testing
- Atmospheric Pressure Non-Thermal Plasma, Standard Surgical Wound Care Protocol
- Where
- Mexico
- Volunteers
- 26 people
- Sponsor
- National Institute of Nuclear Research - Mexico
Diabetes, Cataract
Healing of Corneal Incision After Cataract Surgery in Diabetic Patients
The objective of this observational study was to understand the healing of corneal incision after cataract surgery in diabetic patients and its influencing factors.
- Trial name
- NCT07076420
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Zhongnan Hospital
Postoperative Recovery, Wound Healing
The Effect of TENS Applied in the Early Postpartum Period on Incision Healing, Pain and Comfort
Objective: In this study, it was aimed to determine the effect of TENS applied in the early postpartum period after cesarean section on incision healing, pain and comfort.
- Conditions
- Postoperative Recovery, Wound Healing, Postpartum Comfort, Postpartum Pain
- Trial name
- NCT05991921
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS), Plasebo-Fake TENS
- Where
- Turkey (Türkiye)
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Inonu University
Carbuncle
Comparison of Wound Healing for Diabetic Carbuncle Treated With Incision and Drainage Technique Using Cruciate Incision vs Saucerization Technique Both Followed by Vacuum Assisted Closure.
The goal of this clinical trial is to compare the effectiveness of two surgical techniques for wound healing in diabetic patients aged 25-70 years with a carbuncle requiring surgical drainage.
- Trial name
- NCT07428265
- Testing
- Incision & Drainage Technique Using Cruciate Incision Followed by VAC, Saucerization Technique Followed by VAC
- Where
- Pakistan
- Volunteers
- 124 people
- Sponsor
- King Edward Medical University
Surgical Wound
Effect of Replacing Buried Sutures With Tissue Adhesive on Aesthetic Outcome of Surgical Wounds.
Surgery wounds are typically closed with combination of absorbable stitches placed under the skin and non-absorbable stitched placed at the skin surface.
- Trial name
- NCT03425370
- Testing
- Closure of surgical wounds using buried sutures or tissue adhesive on aesthetic outcome.
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- West Virginia University
Wound Healing, Mohs Micrographic Surgery
Topical 0.5% Timolol Solution for Healing Lower Extremity Wounds
Topical timolol, a β2-Adrenergic receptor (B2AR) antagonist, has demonstrated promise in wound healing over the past several years.
- Trial name
- NCT06941467
- Testing
- Timolol Maleate Solution, Standard of Care
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Sepsis, Burn Injury
Surgical Critical Care Initiative (SC2i) Tissue and Data Acquisition Protocol (TDAP) in Burn Patients Improving the Robustness and Generalizability of Post-burn Sepsis Prediction With the Post-Burn Sepsis Digital Twin. Group 1
This study is following adult patients with serious burn injuries to better understand how their bodies respond to treatment and recovery.
- Conditions
- Sepsis, Burn Injury, Wound Healing, Critical Illness
- Trial name
- NCT07249762
- Testing
- Observational Cohort (No Intervention)
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Breast Surgery, Regeneration
Clinical Investigation of an Ozonated Oil for the Regeneration and Healing of Surgical Wounds in Patients Undergoing Breast Surgery
This is a multicentre, prospective, randomised, double-blind, placebo-controlled clinical study designed to evaluate the regenerative and wound-healing efficacy of OZOAQUA MD OZONATED OIL in surgical wounds in patients undergoing…
- Conditions
- Breast Surgery, Regeneration, Surgical Wound Healing
- Trial name
- NCT07809308
- Testing
- ozonated oil, Non ozonated oil
- Where
- 2 sites in Spain
- Volunteers
- 50 people
- Sponsor
- Laboratorios Ozoaqua
Wound Heal, Vestibular Abnormality
Comparison of Diode Laser-Assisted Vestibuloplasty And Conventional Vestibuloplasty
Randomized controlled parallel designed clinical study aimed to compare vestibule depth gain and dimensional changes of wound area in individuals who underwent vestibule deepening surgery using diode laser and conventional…
- Conditions
- Wound Heal, Vestibular Abnormality, Low-level Light Therapy, Surgical Wound
- Trial name
- NCT05252260
- Testing
- Diode Laser, Conventional Surgery, Low level laser therapy (LLLT)
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Apical Periodontitis, Endodontically Treated Teeth
Effect of Photobiomodulation on Pain and Healing of the Vertical Releasing Incision After Endodontic Microsurgery
The purpose of this study is to evaluate the effect of Photobiomodulation (PBM) in postoperative pain after endodontic microsurgery (EMS) in patients from the University of Texas Health Science Center at Houston, School of…
- Conditions
- Apical Periodontitis, Endodontically Treated Teeth, Endodontic Disease, Apical Cyst
- Trial name
- NCT06574152
- Testing
- PBM treatment, EMS
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- The University of Texas Health Science Center, Houston
Abscess
The Effect Of Wound Irrigation With Irrisept™ Delivery System On Abscess Healing In Patients Presenting To The Emergency Department
The purpose of this study is to determine if wound cleansing and irrigation using the IRRISEPT Chlorhexidine Gluconate(CHG)solution, applying a given volume with a pressurized stream, will improve the outcome for infected…
- Trial name
- NCT01302548
- Testing
- IRRISEPT, Usual Care
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Florida
Diverting Ileostomy, Rectal Cancer
Purse-String Versus Linear Closure After Ileostomy Reversal
This randomized study compared two wound closure and wound care protocols after reversal of a diverting ileostomy in adults previously treated surgically for rectal cancer.
- Trial name
- NCT07892404
- Testing
- Linear Wound Management Protocol, Purse-String Wound Management Protocol
- Where
- Ukraine
- Volunteers
- 23 people
- Sponsor
- Dnipro Regional Clinical Oncology Dispensary
Postoperative Complications, Surgical Site Infection
Hierarchy of Effects of Laboratory Markers and Their Interaction With Comorbidity Concerning Outcome and Personalized Treatment of Trauma Patients in Emergency Care and Rehabilitation
At least ten percent of trauma patients suffer from any sort of complication. The study aims to identify a risk factor profile to early identify trauma patients at risk.
- Conditions
- Postoperative Complications, Surgical Site Infection, Wound Infection, Non-healing Wound
- Trial name
- HELICOPTER (NCT06758427)
- Where
- Germany
- Volunteers
- 2,300 people
- Sponsor
- Department of Trauma and Reconstructive Surgery at Eberhard Karls University Tuebingen, BG Klinik Tu
Wounds and Injuries
A Study to Evaluate the Efficacy of Microlyte Matrix in the Management of Donor Site Wounds
A study to to evaluate the efficacy of Microlyte® Matrix by demonstrating its superiority to the standard of care in the healing of donor site wounds in patients requiring split-thickness grafting, as well as to assess the…
- Trial name
- NCT05439746
- Testing
- Microlyte® Matrix
- Volunteers
- 53 people
- Sponsor
- Imbed Biosciences
Surgical Wound, Post Operative Pain
Effect of Preemptive Etoricoxib and Dexamethasone on Wound Healing and Clinical Parameters After Third Molar Surgery
The goal of this clinical trial is to compare preemptive single-dose selective cyclooxygenase 2 (COX-2) inhibitor - etoricoxib and dexamethasone use in systemically healthy patients during the surgical extraction of impacted…
- Trial name
- NCT05791721
- Testing
- Etoricoxib 90 Mg Oral Tablet, Dexamethasone 4mg
- Where
- Serbia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Belgrade