Clinical trials: Health
Premature Ovarian Insufficiency, Reproductive Health
Microbiome and Premature Ovarian Insufficiency
This study investigates the differences in gut and vaginal microbiota between women with premature ovarian insufficiency (POI) and healthy volunteers.
- Trial name
- NCT07275671
- Where
- 2 sites in China
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Westlake University
Health Adult Subjects
Prefrontal Neuroplasticity and Coping Strategies in Healthy Population
The current study serves as a pilot for the GRF project "Predicting illness trajectories in fully remitted major depression using concurrent TBS/fNIRS." The project examines whether intermittent theta-burst stimulation (iTBS)…
- Trial name
- NCT07433829
- Testing
- Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Burnout, Healthcare Workers, Clinical Workflow Optimization
AI Tool to Reduce Clinician Documentation Burden
This study looks at whether a clinician-facing artificial intelligence (AI) tool can help outpatient doctors spend less time reviewing medical records and documenting care.
- Conditions
- Burnout, Healthcare Workers, Clinical Workflow Optimization, Health Information Technology, Electronic Health Records
- Trial name
- Evidently (NCT07498582)
- Testing
- AI Clinical Summarization Tool (Evidently)
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Ankylosing Spondylitis (AS), Mental Health
An Ecological Momentary Intervention for Mental Health in Individuals With Ankylosing Spondylitis
Ankylosing spondylitis is a chronic inflammatory rheumatic disease associated with pain, stiffness, reduced mobility, and impaired quality of life.
- Trial name
- NCT07647965
- Testing
- Ecological Momentary Intervention, Attention Control Group
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 36 people
- Sponsor
- The Hong Kong Polytechnic University
Caregiver Burden, Quality of Life
Care Burden And Qualıty of Lıfe
This randomized controlled trial will be conducted to examine the effect of a multidimensional training program, to be implemented by a public health nurse, on the care burden and quality of life of primary caregivers of patients…
- Conditions
- Caregiver Burden, Quality of Life, Public Health
- Trial name
- Care Burden (NCT07672340)
- Testing
- Health Promotion Behavior Education
- Volunteers
- 78 people
- Sponsor
- Aydin Adnan Menderes University
Breast Neoplasms, HER2/Neu Positive
Tolerability of the Combination of Lapatinib and Trastuzumab in Adults Age 60 or Older With HER2 Positive Locally Advanced or Metastatic Breast Cancer
This phase II trial studies the side effects and how well lapatinib ditosylate and trastuzumab work in treating older patients with human epidermal growth factor receptor 2 (HER2)-positive breast cancer that has spread from where…
- Conditions
- Breast Neoplasms, HER2/Neu Positive, Geriatric Health Services
- Trial name
- NCT01273610
- Testing
- Lapatinib, Trastuzumab, laboratory biomarker analysis
- Where
- 8 sites in United States
- Volunteers
- 40 people
- Sponsor
- City of Hope Medical Center
COPD, Health Literacy
Health Literacy, Physical and Cognitive Function, Health-related Behaviors, and Quality of Life in COPD
Health literacy is important for controlling disease progression and living a healthy life with illness. High health literacy is associated with higher cognitive performance and lower health-related quality of life.
- Conditions
- COPD, Health Literacy, Health-Related Behavior
- Trial name
- NCT06497816
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Ventilator-Associated Pneumonia (VAP), Neonatal, Bronchopulmonary Dysplasia (BPD)
National Surveillance and Prevention of Neonatal VAP
The goal of this observational study is to improve how hospital-acquired lung infections (called ventilator-associated pneumonia, or VAP) are diagnosed, treated and prevented in very low birth weight (VLBW) infants, babies born…
- Conditions
- Ventilator-Associated Pneumonia (VAP), Neonatal, Bronchopulmonary Dysplasia (BPD), Antibiotic-Resistant Organisms (AROs), Health-Care Associated Infection (HAI)
- Trial name
- NCT07109791
- Where
- Canada
- Volunteers
- 1,500 people
- Sponsor
- University of Alberta
Health Disparities, Education
Clean Beauty in Newark, NJ
Every day, consumers use personal care products containing thousands of manmade chemicals. Growing evidence suggests that personal care products specifically marketed to Black women (e.g., hair straighteners and oils, skin…
- Trial name
- NCT07216898
- Testing
- Chemical Exposure Prevention
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Bullying Victimization, School Bullying
Nurse-Led Take a SELSTEP Program on Peer Bullying, Victimization, and Bystander Behavior Among Adolescents
This randomized controlled trial will evaluate the effect of a nurse-led social emotional learning (SEL) program on bullying, victimization, and bystander behaviors among adolescents.
- Conditions
- Bullying Victimization, School Bullying, School Health, School Based Intervention
- Trial name
- Take a SELSTEP (NCT07372456)
- Testing
- Nurse-Led Take a SELSTEP Program
- Where
- Turkey (Türkiye)
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Marmara University
HIV Infection, Acquired Immune Deficiency Syndrome
Dental Management of Patients With HIV in Pays de la Loire
Dental care for people living with HIV has evolved with the widespread use of antiretroviral therapy, which has improved life expectancy and disease control.
- Conditions
- HIV Infection, Acquired Immune Deficiency Syndrome, Oral Health Care
- Trial name
- VIH-ODONTO (NCT07552038)
- Testing
- HIV infection status and clinical characteristics
- Where
- France
- Volunteers
- 5,603 people
- Sponsor
- Nantes University Hospital
Cardiovascular Health
Mind Your Heart Intervention for American Indian Women
The goal of this clinical trial is to learn if a culturally-adapted intervention can improve cardiovascular health in American Indian women.
- Trial name
- MYH (NCT07581899)
- Testing
- Culturally-adapted intervention to improve cardiovascular health in American Indian women
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of North Carolina, Chapel Hill
Dental Caries, Bleeding on Probing
Evaluating Methods of Dental Health Instructions on the Oral Health Indices of 12-18-year-old Patients With Fixed Orthodontics
The goal of this clinical trial is to learn which type of oral health education works best to help 12-18-year-old participants with fixed orthodontic appliances (braces) keep their mouths healthy.
- Conditions
- Dental Caries, Bleeding on Probing, Gingival Index, Plaque Index
- Trial name
- NCT07667283
- Testing
- Verbal Oral Hygiene Instruction, Pamphlet-Based Oral Hygiene Instruction, Video-Based Oral Hygiene Instruction
- Where
- Iran
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Violence, Parenting
Evaluating the Effectiveness of the Common Elements Treatment Approach (CETA) in Peru: Mechanisms of Individual and Intergenerational Change
Recent advances in intervention research have revealed the promise of transdiagnostic, modular approaches implemented by lay paraprofessionals for the treatment of the most prevalent mental health concerns in settings affected by…
- Conditions
- Violence, Parenting, Poverty, Depression
- Trial name
- NCT07667738
- Testing
- Common Elements Treatment Approach, Enhanced Case Managment
- Where
- Peru
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Notre Dame
Obesity (Disorder), Body Image
3D Reconstruction, VR and Machine Learning in Body Image in Bariatrics
Studies have shown that following bariatric metabolic surgery (BMS), patients continue to experience dissatisfaction with their new body image and identity).
- Conditions
- Obesity (Disorder), Body Image, Mental Health, Bariatric Surgery
- Trial name
- NCT07668492
- Testing
- Body Image Counselling with Virtual Reality
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- Imperial College London
Hydration, Dehydration
Multimedia Hydration Education During Physical Education in Schoolchildren
Here's a plain-language Brief Summary ready to paste - it follows the PRS lay-language style (short sentences, explains the "why," avoids jargon) and fits well within 5,000 characters: Staying well hydrated helps children stay…
- Conditions
- Hydration, Dehydration, Health Behavior, Drinking Behavior
- Trial name
- NCT07669909
- Testing
- Multimedia hydration education programme
- Where
- 2 sites in Tunisia
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- The Higher Institute of Sport and Physical Education of Sfax
Emergency Medical Service Communication Systems, Health Care
Modeling the Impact of Inbound Call Distribution Virtualization in Emergency Medical Communication Centers (EMCCs) on Their Service Level
Fast access to the Emergency Medical Communication Center (EMCC) is essential for the population in emergency situation. It is therefore essential that these call centers operate quickly and provide good quality service.
- Trial name
- CALL_SAMU (NCT04670835)
- Where
- France
- Volunteers
- 1,088,000 people
- Sponsor
- Nantes University Hospital
Primary Care, Health Plan Implementation
Effectiveness of a Joint General Practitioner-Pharmacist Intervention on Benzodiazepine Deprescribing in the Elderly
Benzodiazepines or related drug (BZDR) are consumed for hypnotic or anxiolytic purposes in most cases. The consequences of BZDR are multiple with an increased risk of daytime sedation, balance disorders leading to falls and…
- Conditions
- Primary Care, Health Plan Implementation, Benzodiazepine Dependence, Elderly
- Trial name
- BESTOPH-MG (NCT05765656)
- Testing
- GP - pharmacist collaboration and pharmacist motivational interviewing
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Nantes University Hospital
Occupational Health
Adaptation of SFA for HRW
The aim of this study is to pilot and test the feasibility, acceptability, and effectiveness of a Stress First Aid (SFA) intervention adapted for Harm Reduction Workers (HRWs) serving Persons Who Use Drugs.
- Trial name
- NCT07149155
- Testing
- Stress First Aid for Harm Reduction Workers
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Suzannah Creech
Peri-implant Health, Peri-implant Mucositis
Effect of Probe Material on Peri-implant Probing
Evaluate whether the type of probe (plastic vs. metallic) modifies the accuracy of peri-implant probing in single-unit implants, by comparing the probing depth recorded with the prosthesis in place versus without the prosthesis…
- Trial name
- METPLA-PP (NCT07304752)
- Testing
- Metallic UNC-15 periodontal probe, Plastic UNC-15 periodontal probe
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- University of Barcelona
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