Clinical trials: Health Adults
App Engagement, Employee Health
Can Mindsets Predict Help-Seeking? A Growth Mindset Intervention and Mental Health App Engagement in Working Adults
Despite the growing adoption of digital mental health initiatives in the workplace, employees' sustained engagement with these resources remained relatively low.
- Conditions
- App Engagement, Employee Health, Mobile Apps, Self-care Tools
- Trial name
- GROW (NCT07071311)
- Testing
- Growth Mindset Intervention, Digital Technology Condition
- Where
- Singapore
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- Intellect Pte. Ltd.
PreDiabetes
Efficacy and Safety of Digital Therapeutic in Adults With Prediabetes
The study aims to evaluate the efficacy and safety of a digital therapeutic (TH-001) for adult individuals with prediabetes.
- Trial name
- NCT05668819
- Testing
- TH-001
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Tesu Saglik Teknolojileri A.S.
Healthy
A Study to Evaluate the Safety and Immunogenicity of Seasonal Influenza Vaccine and an Adenovirus Serotype 26- Based Vaccine Encoding for the Respiratory Syncytial Virus Pre-fusion F Protein (Ad26.RSV.preF), With and Without Co-administration, in Adults Aged 60 Years and Older in Stable Health
The purpose of this study is to demonstrate the non-inferiority of the concomitant administration of an adenovirus serotype 26- based vaccine encoding for the respiratory syncytial virus pre-fusion F protein (Ad26.RSV.preF) and…
- Trial name
- NCT03339713
- Testing
- Ad26.RSV.preF, Fluarix
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Janssen Vaccines & Prevention B.V.
Smoking Cessation
Comparison of Pharmacokinetic Profiles of 3 New Nicotine Gum Formulations With a Reference Gum
The purpose of the study is to compare the pharmacokinetic (PK) profiles and assess bioequivalence between three new nicotine gum formulations and a reference nicotine gum in healthy smokers.
- Trial name
- NCT02356913
- Testing
- Nicotine gum
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Fertin Pharma A/S
Obesity or Overweight
Study of Once-Daily Oral RGT001-075 Compared With Placebo in Adults With Obesity or Are Overweight With Weight-Related Health Conditions
This is a phase 2, 36-week randomized, double-blind, placebo-controlled, parallel arm study that will evaluate the safety, tolerability, weight loss efficacy, pharmacodynamic effects, and pharmacokinetics of RGT001-075 in adults…
- Trial name
- COMO-1 (NCT06867718)
- Testing
- RGT001-075
- Where
- 35 sites in United States
- Volunteers
- 267 people
- Sponsor
- Regor Pharmaceuticals Inc.
Healthy Adults
Pilot Study of the Entarik System With Advanced Functionality in Health Adults
In this single-site study, data will be recorded during nasogastric or orogastric placement (and post-pyloric placement) and removal of the Entarik Feeding Tube.
- Trial name
- NCT06660758
- Testing
- Feeding tube (Entarik)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gravitas Medical, Inc.
Bowel Obstruction
A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B302
This study is designed to compare the standard of care against EXPAREL (bupivacaine liposome extended-release injectable suspension) to determine if total opioid consumption is reduced when using EXPAREL, therefore possibly…
- Trial name
- IMPROVE-Open (NCT01507233)
- Testing
- IV morphine sulfate, EXPAREL (bupivacaine liposome injectable suspension)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Insulin Resistance
Efficacy Pilot Study of Triflusal in the Attenuation of Insulin Resistance in Human Obesity
To explore the efficacy of triflusal in the attenuation of insulin resistance in human obesity. Triflusal is a salicylate compound approved in several countries as antithrombotic agent (antiplatelet).
- Trial name
- NCT00162799
- Testing
- Triflusal (DCI)
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- J. Uriach and Company
Health, Subjective
A Study to Evaluate the Pharmacokinetics and Safety of HIP1701 in Healthy Subjects
An open-label, randomized, single-dose crossover study to evaluate the pharmacokinetics and safety of HIP1701 in healthy subjects.
- Trial name
- NCT04087525
- Testing
- HIP1701, HGP1809
- Where
- South Korea
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Hanmi Pharmaceutical Company Limited
Social Anxiety Disorder
A Clinical Trial to Assess the Efficacy, Safety, and Tolerability of a Repeat Dose of Fasedienol Nasal Spray for the Acute Treatment of Anxiety in Adults With Social Anxiety Disorder
This U.S. multicenter, double-blind, placebo-controlled Phase 2 clinical trial is designed to evaluate the efficacy, safety, and tolerability of a repeat intranasal (i.n.) dose of Fasedienol Nasal Spray (fasedienol) (3.2 µg) to…
- Trial name
- NCT06809179
- Testing
- Fasedienol Nasal Spray - Fasedienol Nasal Spray
- Where
- 9 sites in United States
- Volunteers
- 60 people
- Sponsor
- VistaGen Therapeutics, Inc.
Bioavailability
Theracurmin vs Curcumin Bioavailability Study
A randomized, open-label, cross-over, single administration study to compare bioavailability of curcumin in health adults
- Trial name
- NCT04028739
- Testing
- curmin
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Handok Inc.
Health, Subjective
A Drug-Drug Interaction Study of CTL0801 and CTL0802 Compared to Coadministration in Healthy Adult Volunteers
This is a two-arm, open-label, single-sequence, multiple-dose, cross-over phase 1 study to evaluate the interaction between two investigational drugs by comparing and analyzing the pharmacokinetic interaction and safety of…
- Trial name
- NCT05002244
- Testing
- CTL0801 (Azilsartan), CTL0802 (Rosuvastatin), CTL0801 (Azilsartan) + CTL0802 (Rosuvastatin)
- Where
- South Korea
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Celltrion
Dietary Supplement, Cognition
Nutritional Supplement's Effects on Cognition
This is a prospective, placebo controlled study, examining the effects of dietary supplement's effects on cognition and confirming safety.
- Conditions
- Dietary Supplement, Cognition, Healthy
- Trial name
- NCT05941949
- Testing
- Softgel Cognitive Formulation containing Astaxanthin, Grape Juice Extract and All Natural Vitamin E
- Where
- Australia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Pharmanex
Transitional Cell Carcinoma
JAVLOR® Online Non-Interventional Trial
Documentation of data concerning tolerability and efficacy of the intravenous treatment with vinflunine performed under daily routine conditions in Germany.
- Trial name
- JONAS-1 (NCT01103544)
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Pierre Fabre Pharma GmbH
Metastatic Breast Cancer, Breast Neoplasms
Treatment Patterns and Clinical Outcomes Among Talazoparib-Treated Adults With HER2-Negative mBC With gBRCA1/2m
This non-interventional retrospective study will describe real-world treatment patterns and clinical outcomes among adults with HER2-negative metastatic breast cancer with germline BRCA1/2 mutations who initiated talazoparib as a…
- Trial name
- NCT05141708
- Testing
- Talazoparib
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Pfizer
Lyme Disease
Novel Diagnostics for Early Lyme Disease
There are more than 300,000 new cases of Lyme disease every year in the US. Lyme disease is a dangerous bacterial infection transmitted by tick bites and it becomes increasingly severe as the infection progresses.
- Trial name
- NCT03963635
- Testing
- MicroB-plex Lyme Immunoassay
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- MicroB-plex, Inc.
Healthy Volunteers
A Study on the Safety, Tolerability, Bioavailability and Mechanism of Action of Intravenous NAV-240 in Adults.
The goal of this clinical trial is to assess initial safety/tolerability of multiple doses of drug NAV-240. It will also learn about the profile and immunogenicity of drug NAV-240.
- Trial name
- NCT06933043
- Testing
- NAV-240
- Where
- Australia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Navigator Medicines, Inc.
Smoking Cessation
A Single Dose-escalation Study of Cytisine in Adult Smokers
The objectives of this study are: 1. To assess the tolerability and safety of cytisine as a single oral dose. 2. To define the Cmax levels associated to the occurrence of dose-limiting adverse events.
- Trial name
- NCT03848208
- Testing
- cytisine
- Where
- Portugal
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Achieve Life Sciences
Obesity, Overweight
A Study of Orforglipron (LY3502970) in Chinese Participants With Obesity or Overweight and Weight-Related Health Problems
The purpose of this study is to learn how well orforglipron works and how safe it is in Chinese adults with obesity or overweight and related health problems. Participation in this study will last about 53 weeks (about 1 year).
- Trial name
- ATTAIN-CN (NCT07790861)
- Testing
- Orforglipron
- Where
- 13 sites in China
- Volunteers
- 192 people
- Sponsor
- Eli Lilly and Company
Diabetes Mellitus, Type 2
A Research Study Comparing RYBELSUS® to Other Blood Sugar Lowering Tablets in People Living in America With Type 2 Diabetes (REALYSE)
This study is comparing the medicine RYBELSUS® to other medicines in people with type 2 diabetes who need extra treatment. All medicines used in this study are tablets which lower blood sugar in people with type 2 diabetes.
- Trial name
- REALYSE (NCT05035082)
- Testing
- semaglutide, oral glucose-lowering medications (commercially available)
- Where
- 25 sites in United States
- Volunteers
- 1,018 people
- Sponsor
- Novo Nordisk A/S