Clinical trials: Health Behavior / Well-Being
Diabetes Type 2, Periodontal Disease
Evaluate the Efficacy of an Oral Health Behavioral Intervention in People With Diabetes
The purpose of this clinical study is to evaluate the effect of a behavioral intervention on the number of preventive and treatment dental claims in a population of people with Type 2 Diabetes.
- Conditions
- Diabetes Type 2, Periodontal Disease, Caries
- Trial name
- NCT07619729
- Testing
- Diabetes Oral Health Program, Stannous Fluoride Dentifrice, Cetylpyridinium Chloride (CPC) and Zinc Lactate Mouthwash
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- Colgate Palmolive
Smoking Cessation
Study to Evaluate Electrocardiographic Effects of Therapeutic & Supratherapeutic Doses of Cytisinicline in Healthy Smokers
The primary objective of this trial is to assess the effects of cytisinicline at therapeutic and supratherapeutic doses on cardiac repolarization relative to placebo in healthy adult subjects who are smokers.
- Trial name
- NCT05566288
- Testing
- Cytisinicline, Moxifloxacin
- Where
- Portugal
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Achieve Life Sciences
Health Behavior
New Stage 1 Formula on Gut Comfort and Gut Health
180 qualified subjects aged from 7 days to 90 days will be enrolled with the 144 completed in study (allowing for a 20% drop-out rate).
- Trial name
- NCT02406937
- Testing
- Oral intake of Feihe New Formula, Oral intake of Feihe Stage 1 Formula, Breast Feeding
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Heilongjiang Feihe Dairy Co. Ltd.
Cognitive Wellness, Healthy Aging
MEVA Cognitive Wellness Platform Study for Adults
The goal of this observational study is to evaluate the reliability, usability, and feasibility of the MEVA Cognitive Wellness Platform in community-dwelling adults aged 55 to 75.
- Conditions
- Cognitive Wellness, Healthy Aging, Age-Related Cognitive Change, Aging
- Trial name
- MEVA (NCT07595250)
- Testing
- MEVA Cognitive Wellness Platform
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mentage LLC
Smoking Cessation
Enhanced E-cigarette Coaching Intervention for Dual Users of Cigarettes and E-cigarettes
The purpose of this study is to develop and pilot test an enhanced behavioral coaching intervention for dual users of cigarettes and electronic nicotine delivery systems (ENDS) who call tobacco quitlines for help quitting smoking.
- Trial name
- NCT03575468
- Testing
- Enhanced E-cigarette Coaching, Quitline treatment as usual
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Consumer Wellness Solutions
Opioid Dependence, Opioid Use
Impact of a Behavioral Tele-health Program on the Quality of Recovery for Patients Undergoing Total Joint Replacement Surgery
The quality of recovery after surgery is multi-factorial and includes both physical and mental factors. Persistent pain after surgery is a common problem after major surgery and can result in persistent opioid use.
- Conditions
- Opioid Dependence, Opioid Use, Pain, Joint
- Trial name
- NCT05367050
- Testing
- Lucid Lane Therapy Program, Surgical Preparedness Course
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Lucid Lane, Inc
Epilepsy
Valproate Sustained Release Minitablets (Orfiril(R) Long) Once Daily in the Evening
Valproate is the first line therapy in primary generalized seizures. The applied drug contains sodium valproate in sustained release minitablets.
- Trial name
- NCT00870688
- Testing
- sodium valproate
- Volunteers
- 82 people
- Sponsor
- Desitin Arzneimittel GmbH
ADHD, Gastrointestinal
ADHD, Gut Problems and Synbiotic
The scope of this study is to evaluate the impact of a synbiotic product (a combination of probiotic bacteria and prebiotics) on symptoms reported by participants with ADHD.
- Conditions
- ADHD, Gastrointestinal, Emotion Regulation Abilities
- Trial name
- NCT07717359
- Testing
- Synbiotic Cap Gut-Brain
- Volunteers
- 174 people
- Sponsor
- Super Synbiotics AB
Lung Cancer
Airway Epithelium Gene Expression: AEGIS IDE
The purpose of the research study is to develop a new, more sensitive, and less invasive test for diagnosing lung cancer at an earlier stage, when it can more easily be cured.
- Trial name
- AEGIS IDE (NCT00746759)
- Testing
- Biomarker (not used as an intervention)
- Where
- 21 sites in United States
- Volunteers
- 1,331 people
- Sponsor
- Allegro Diagnostics, Corp.
Obesity
Noom Coach for Bariatric Surgery
The prevalence of overweight in America is a national public health crisis. As more people consider bariatric surgery for the treatment of severe obesity, it is imperative to identify factors influencing surgical outcomes.
- Trial name
- NCT03386006
- Testing
- Noom Coach for Bariatric Health
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Noom Inc.
Mastitis, Breast Milk
Effect of Probiotics Consumed During Pregnancy on the Incidence of Mastitis
The aim of the present study is to evaluate the effect of consumption during pregnancy and the lactation period of the probiotic L. fermentum CECT5716 on the incidence of mastitis.
- Conditions
- Mastitis, Breast Milk, Lactation, Women's Health
- Trial name
- NCT04032899
- Testing
- Lactobacillus fermentum CECT5716, Maltodextrin
- Where
- 3 sites in Spain
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Biosearch S.A.
Frail Elderly Syndrome
A Machine Learning Algorithm to Predict Health Clinical Situations in Primary Healthcare for Frail Older Adults.
Introduction: We developed a machine learning algorithm to predict the risk of emergency hospitalization within the new 7 to 14 days with a good predictive performance (AUC=0.85).
- Trial name
- NCT06013709
- Testing
- PRESAE CARE
- Volunteers
- 1,478 people
- Sponsor
- Presage
Alzheimer Disease, Dementia
Preventing Medication Mismanagement in People Living With Dementia Through Automated Medication Dispensing With Facial Recognition and Video Observation
Globally, >47M individuals live with dementia, with new incidence of 7.7M annually. Medication mismanagement is one of the most common and concerning risk factors in people with dementia (PwD), as it leads to undertreatment…
- Conditions
- Alzheimer Disease, Dementia, Medication Adherence, Type 2 Diabetes Mellitus (T2DM)
- Trial name
- NCT06691256
- Testing
- HiDO-ALZ
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- HiDO Technologies
Hearing Loss
Evaluating an Audiology Text-Message Protocol to Support Hearing Aid Use in NHS Adult Audiology Patients
Over 18 million adults in the United Kingdom have significant hearing loss, linked to isolation, depression and comorbidities. Hearing aids are the main management option yet are frequently unused (~23%) or used irregularly…
- Trial name
- NCT07146607
- Testing
- Audiology text-message protocol
- Where
- 3 sites in United Kingdom
- Volunteers
- 70 people
- Sponsor
- WSAUD A/S
Fertility Issues, Emotional Stress
Frame Support Study
This is a randomized, controlled pilot study evaluating an intervention of non-significant risk. Potential subjects will be women who have completed an initial new patient consultation at one of the participating fertility…
- Trial name
- NCT07083700
- Testing
- Frame Access
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Inception Fertility Research Institute, LLC
Healthy, Metabolism
Personalized Dietary Program and Markers of Wellness
The objective of this study is to determine the impact of an integrated personalized dietary and wellness program which includes dietary advice, meals, and counseling on health and wellness.
- Trial name
- NCT03424395
- Testing
- Personalized dietary and wellness program
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Habit, LLC
Smoking Cessation
Comparison of the Efficacy and Safety of 2 Oral Doses of Rimonabant, 5 mg/Day or 20 mg/Day, Versus Placebo, as an Aid to Smoking Cessation (STRATUS US)
The primary study objective was to assess the efficacy of 2 fixed doses of rimonabant versus placebo on abstinence from tobacco use in cigarette smokers.
- Trial name
- NCT00358228
- Testing
- Rimonabant
- Where
- United States
- Volunteers
- 787 people
- Sponsor
- Sanofi
Menopause, Perimenopausal Disorder
Virtual perI-/Menopause Registry of AusTrALia
13 million (50.7%) Australians are born with ovaries, 14% (~3 million) are currently aged 40-59 yrs, \& all such who live to midlife will experience menopause, defined as >12 months without a period.
- Conditions
- Menopause, Perimenopausal Disorder, Postmenopausal Symptoms, Health Knowledge, Attitudes, Practice
- Trial name
- VITAL (NCT06487130)
- Testing
- N/A Observational Registry
- Where
- Australia
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Bespoke Clinical Research
Smoking Cessation
Single-Dose Bioequivalence Study Comparing Two 4 mg Nicotine Lozenges
The purpose of the study is to compare the pharmacokinetic (PK) profiles and assess bioequivalence between a new nicotine lozenge and a reference nicotine lozenge in healthy smokers
- Trial name
- NCT03432312
- Testing
- Nicotine lozenge
- Where
- South Africa
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Fertin Pharma A/S
HIV Infections
The Effect of Teaching HIV-Infected Patients About HIV and Treatment
The purpose of this study is to see if an HIV-education course can help under-represented, HIV-infected patients. This study examines the areas of faithfulness to drug regimen, level of HIV in the blood, and health status.
- Trial name
- NCT00002409
- Testing
- Lamivudine/Zidovudine, Abacavir sulfate
- Where
- 25 sites in United States
- Volunteers
- 200 people
- Sponsor
- Glaxo Wellcome