Clinical trials: Health Care Acceptability
Malaria
Factors Influencing Adoption of a Novel Malaria Treatment in Côte d'Ivoire, Ghana, and Rwanda
This non-interventional qualitative study will examine factors that influence the adoption of a novel malaria treatment in Côte d'Ivoire, Ghana, and Rwanda.
- Trial name
- NCT07896746
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Critical Illness, Psychological Distress
Messy Memories: Mobile Application Therapy Following Critical Illness
The overall goal of this study is to determine whether English-speaking adults who were discharged from an intensive care unit (ICU) at least one month ago and have some level of distress related to their ICU experience will be…
- Conditions
- Critical Illness, Psychological Distress, Health Behavior
- Trial name
- NCT05849454
- Testing
- Messy Memories Intervention
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Columbia University
Mental Disorders
Reducing Stigma Among Healthcare Providers to Improve Mental Health Services
A growing number of trials have demonstrated treatment effectiveness for people with mental illness (PWMI) by non-specialist providers, such as primary care and community health workers, in low-resource settings.
- Trial name
- RESHAPE-mh (NCT02793271)
- Testing
- RESHAPE, PRIME/mhGAP
- Where
- Nepal
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Brandon A Kohrt, MD, PhD
AI (Artificial Intelligence), Osteoporosis
Evaluation of Dora Care for Supporting Fracture Liaison Services (FLS)
What is the study about? This study is testing "Dora", an AI-powered assistant that can make phone calls to patients, for use in the Fracture Liaison Service (FLS).
- Conditions
- AI (Artificial Intelligence), Osteoporosis, Outpatient, Telemedicine
- Trial name
- NCT07464171
- Testing
- Dora call
- Volunteers
- 217 people
- Sponsor
- Ufonia
Medication Adherence, Adjustment Reaction With Anxiety and Depression
Mindfulness and Acceptance Based Therapy for Adolescents Living With HIV
Adolescents represent a growing share of people living with HIV in sub-Saharan Africa (SSA), yet show poor adherence to medication and viral suppression (VS) compared to adults.
- Conditions
- Medication Adherence, Adjustment Reaction With Anxiety and Depression, Mental Health Issue
- Trial name
- NCT05010317
- Testing
- Mindfulness and acceptance based therapy, Standard of care
- Where
- 2 sites in Uganda
- Volunteers
- 122 people
- Sponsor
- Infectious Diseases Research Collaboration, Uganda
Human Immunodeficiency Virus
Mother and Infant Visit Adherence and Treatment Engagement Study
This is a 2x2 factorial cluster randomized trial of two interventions to improve retention and adherence for women and infants on Option B+.
- Trial name
- MOTIVATE! (NCT02491177)
- Testing
- cMM, Text Messaging
- Where
- Kenya
- Volunteers
- 1,338 people
- Sponsor
- University of Colorado, Denver
Early Childhood Caries, Health Care Acceptability
Effectiveness and Acceptability of SDF Compared to ART for the Management of Early Childhood Caries
The goal of this clinical trial is to assess the acceptability and clinical effectiveness of Silver Diamine Fluoride (SDF) in comparison with Atraumatic Restorative Treatment (ART) in Early Childhood Caries (ECC) management at…
- Trial name
- SDF and ART (NCT06786975)
- Testing
- Silver Diamine Fluoride, Atraumatic Restorative Treatment
- Where
- Chile
- Volunteers
- 156 people
- Sponsor
- Universidad de La Frontera
Chronic Musculoskeletal Pain, Sexual Assault
Post-traumatic Estradiol Administration and Care Evaluation (PEACE)
This pilot randomized, double-blind, placebo-controlled trial evaluates the feasibility, acceptability, and tolerability of administering a single 6 mg oral dose of 17β-estradiol (E2) to individuals assigned female at birth who…
- Conditions
- Chronic Musculoskeletal Pain, Sexual Assault, Posttraumatic Stress Disorder (PTSD)
- Trial name
- PEACE (NCT07868536)
- Testing
- 17β-estradiol
- Volunteers
- 30 people
- Sponsor
- University of North Carolina, Chapel Hill
Oral Cancer, Health Education, Community
Testing and Comparing the Impacts of Mhealth-Based and Web-Based Education on Oral Cancer
Introduction: Oral cancer is a malignant neoplastic disease affecting the lip, oral cavity (mouth) and/or the oropharynx. Despite the intense and diverse public health interventions on oral cancer prevention, the global…
- Conditions
- Oral Cancer, Health Education, Community, Digital Intervention, MHealth Application
- Trial name
- NCT06711848
- Testing
- A web-based educational intervention on oral cancer, A mobile health app-based educational intervention on oral cancer
- Where
- 5 sites in India, Nigeria and 2 more
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Rwanda
HPV Infection
Concordance and Acceptability of Self-screening Versus Screening by a Healthcare Professional for HPV, a Risk Factor for Anal Cancer, by Swab in People Living With HIV
Anal canal cancers are on the increase in France, with around 2,000 new cases per year. These lesions can be detected by directed biopsies or smear tests.
- Trial name
- a-HPVVIH (NCT06507917)
- Testing
- anal swabbing
- Where
- 2 sites in Reunion
- Volunteers
- 398 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Prediabetic State, PreDiabetes
Feasibility of a Nutrition Intervention for Patients With Prediabetes at a Federally Qualified Health Center
The purpose of the study is to assess the feasibility and acceptability of incorporating hands-on nutritional demonstrations to enhance the Diabetes Prevention Program (DPP) curriculum among patients who are at-risk for…
- Conditions
- Prediabetic State, PreDiabetes, Health Knowledge, Attitudes, Practice, Nutrition, Healthy
- Trial name
- NCT06897982
- Testing
- One-arm feasibility pilot of a nutrition intervention to recruit, engage, and retain DPP participants in the safety-net setting in Los Angeles
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cedars-Sinai Medical Center
Mental Health Issue, Inflammatory Bowel Diseases
RxWell in Pediatric IBD for Disease Management and Transition Readiness
Evaluate the feasibility and acceptability of adapted coached RxWell for patients ages 16-25. Adapt and beta test the modified RxWell product to include chronic disease management and transition readiness.
- Trial name
- NCT05461014
- Testing
- dCBI
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Pittsburgh
Stroke, Healthy Health Care Professionals
Usability and Acceptability Study of a Functional Electro-stimulator Controlled by Electromyographic Signal (FitFES)
Functional recovery of the upper limb after a cerebral stroke is one of the major critical issues in rehabilitation. The advent of innovative technologies can be helpful to rehabilitators and intervene where there is no other…
- Trial name
- NCT06763874
- Testing
- EMG-based FES device
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
HIV Infections
Determining Characteristics and Behaviors of Adolescent Women Regarding HIV Risk and Microbicide Trial Participation
This study will examine characteristics and behaviors of young women in India and Tanzania to determine which challenges and opportunities exist for conducting future trials of HIV prevention treatments.
- Trial name
- NCT00872261
- Where
- Tanzania
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- FHI 360
Hypertension, Dyslipidemia
A Novel Digital Tool Clinicians Can Use to Prescribe Exercise to Patients With Cardiovascular Disease Risk Factors
The investigators will conduct a feasibility and pilot efficacy randomized controlled trial to test the usability and user satisfaction of an evidence-based digital health tool the investigators developed for clinicians to use to…
- Conditions
- Hypertension, Dyslipidemia, Diabetes Mellitus, Obesity
- Trial name
- P3-EX (NCT07238556)
- Testing
- Experimental - 12 Week P3-EX Unsupervised Exercise Program with Virtual Weekly Oversight from Graduate Research Assistants, Active Control - 12 Week ACSM-PAVS Unsupervised Exercise Program with Virtual Weekly Oversight from Graduate Research Assistants
- Where
- 3 sites in United States
- Volunteers
- 72 people
- Sponsor
- University of Connecticut
Opioid Use, Opioid Use Disorder
Providing PrEP, Hepatitis C Treatment, and MOUD Through Telemedicine at Greensboro SSP
The purpose of this study is to provide medication for opioid use disorder (MOUD) with buprenorphine and naloxone, or bup/nx, pre-exposure prophylaxis (PrEP) for HIV prevention, and/or hepatitis C treatment for persons who inject…
- Conditions
- Opioid Use, Opioid Use Disorder, Risk Reduction, Hiv
- Trial name
- PARTNERUP (NCT05108935)
- Testing
- Suboxone, Truvada, Mavyret
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- Duke University
Emotion Regulation, Self Efficacy
Skills Video Intervention for Chinese/Chinese Americans
This is a study that aims to test a coping skills intervention delivered via brief animated videos for Chinese and Chinese American college students.
- Conditions
- Emotion Regulation, Self Efficacy, Acceptability of Health Care
- Trial name
- NCT06024083
- Testing
- Dialectical Behavior Therapy skills video intervention
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Sedentary Behavior
Can an Action-based Help-sheet Help People to Move More and Sit Less.
Implementation intentions support people to turn intentions into action, and "Volitional Help-Sheets" are a tool which helps people to form implementation intentions.
- Trial name
- NCT04280250
- Testing
- Volitional Help-Sheet, Control condition
- Volunteers
- 32 people
- Sponsor
- University of Manchester
Bipolar Disorder
Comparative Efficacy and Acceptability of Antimanic Drugs in Acute Mania
Background: Bipolar disorder is one of the most common mental illnesses affecting 1%-4% of the population, and one of the leading causes of worldwide disability.
- Trial name
- NCT01893229
- Testing
- Lithium, Valproate, Oxcarbazepine
- Where
- 2 sites in China
- Volunteers
- 120 people
- Sponsor
- Guiyun Xu
Safety, Psychological, Acceptability of Health Care
Body-oriented Psychotherapy for Individuals With a History of Child Maltreatment and Trauma-related Symptoms
This Pilot Randomized Controlled Trial (RCT) overall aim is to establish the safety, feasibility, acceptability and preliminary effects of a body-oriented psychotherapy, Somatic Experiencing (SE), on social functioning and mental…
- Conditions
- Safety, Psychological, Acceptability of Health Care, Psychological Safety, Maltreatment, Child
- Trial name
- NCT06549777
- Testing
- SE-group, Control
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Monique Pfaltz