Clinical trials: Health Data
Human Immunodeficiency Virus, Treatment Adherence
Data Science and Qualitative Research for Decision Support in the HIV Care Cascade
The goal of this study is to determine whether clinical prediction algorithms derived using statistical machine learning methods can be used to improve patient outcomes in large HIV care programs in sub-Saharan Africa and…
- Conditions
- Human Immunodeficiency Virus, Treatment Adherence, Treatment Compliance, Patient No Show
- Trial name
- CASCADE (NCT06604663)
- Testing
- Activation of the CDSS system
- Where
- Kenya
- Volunteers
- 80,000 people
- Sponsor
- Brown University
Health Behavior
The Impact of Charge Displays on Inpatient Laboratory Test Ordering
This is a clinical trial to evaluate the impact of presenting medicare fee data for inpatient laboratory tests in the electronic health record on provider ordering behavior at a tertiary care hospital.
- Trial name
- NCT02355496
- Testing
- Displaying medicare fee data
- Volunteers
- 98,529 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Chronic Disease
Association Analysis for Chronic Diseases Based on Resident Health Records by Using Big Data Methods
This is an observational study to analysis the association factors for common diseases, including chronic obstructive pulmonary disease, coronary artery disease, hypertension, diabetes etc, based on resident healthcare records.
- Trial name
- NCT03279822
- Testing
- not any intervention
- Where
- China
- Volunteers
- 10,000,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Tongji Hospital, Tongji University School of Medicine
Opiod Use Disorder
Chicago Data-driven Opioid Use Disorder Screening, Engagement, Treatment and Planning System
This study, called the Chicago Data-driven Opioid use disorder Screening, Engagement, Treatment and Planning (C-DOSETaP) System, tests a new system of clinical care for patients with opioid use disorder (OUD) across a large…
- Trial name
- C-DOSETaP (NCT07498322)
- Testing
- OUD screening, MOUD, Continuity of care
- Where
- United States
- Volunteers
- 271,031 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Health Status Unknown
Drug Facts Page or a Short Drug Summary in Helping Patients and Doctors Understand Medical Information
RATIONALE: The way in which information about a drug is provided may affect the ability of patients and doctors to understand how a drug works and the side effects of the drug.
- Trial name
- NCT00450931
- Testing
- counseling intervention, educational intervention
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- White River Junction Veterans Affairs Medical Center
Cardiology, Stroke/TIA
Zio Real-World Evaluation
In 2020 an independent evaluation of the Zio service as part of the Digital Health Technologies programme at NICE was conducted.
- Trial name
- NCT05560828
- Testing
- Zio XT service
- Volunteers
- 1,440 people
- Sponsor
- King's College London
Post-Acute Sequelae of SARS-CoV-2 Infection, Long COVID
Observational Study of Intranasal IVIG in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Patients Undergoing Medical Tourism
This observational study is being conducted by Healing Hope International to collect real-world data on an emerging treatment approach for Long COVID in patients with immunodeficiency.
- Conditions
- Post-Acute Sequelae of SARS-CoV-2 Infection, Long COVID, Long COVID Fatigue, Long COVID Syndrome
- Trial name
- IVIG-LC (NCT06992401)
- Volunteers
- 50 people
- Sponsor
- Tamara C Tamas
Prostate Cancer
Prostate Cancer in UK Prisons: A Retrospective Data Analysis
Prostate cancer is the most common cancer affecting men in the United Kingdom (UK) and is the most common cancer in UK prisons. Early diagnosis is vital because treatment is more effective when the disease is detected at an early…
- Trial name
- PRISON-UK (NCT07870707)
- Where
- United Kingdom
- Volunteers
- 9,007 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Type 2 Diabetes Mellitus, Periodontitis
Oral Health Policy for Patients With Type 2 Diabetes Mellitus in Chile: A Microsimulation Model Based on Real-world Data
The goal of this study is to evaluate the cost-effectiveness of the current proposal and different decision-making scenarios of periodontal care coverage increases for patients with T2DM in Chile.
- Conditions
- Type 2 Diabetes Mellitus, Periodontitis, Diabetic Complication, Dental Care
- Trial name
- NCT05809817
- Testing
- Periodontal treatment
- Where
- 2 sites in Chile
- Volunteers
- 135 people
- Sponsor
- University of Chile
Musculoskeletal Disorders
PRISM: The PRimary Care Individual Social Norms MSK Data Dashboard: a Feasibility Trial
Background: 20 million people in UK have musculoskeletal (MSK) aches and pains. They commonly see their GP about this problem, but practices are so busy that it can mean a long wait for appointments.
- Trial name
- PRISM (NCT07112508)
- Testing
- PRISM dashboard is a data report, THe usual care intervention is a first contact physiotherapy service.
- Where
- 2 sites in United Kingdom
- Volunteers
- 60 people
- Sponsor
- University College, London
Chlamydial Infections
Validation of Chlamydia Diagnostic Codes in TriNetX US EHR Data
This study is a pharmacoepidemiologic method study based on the secondary use of pre-existing data that examines whether TriNetX, a global health research network encompassing a worldwide electronic health record (EHR), database…
- Trial name
- NCT07094373
- Where
- United States
- Volunteers
- 4,878,935 people
- Sponsor
- Sanofi
Plaque Psoriasis
A Real-world Study of Treatment Retention and Adherence to Secukinumab in Patients With Plaque Psoriasis (PsO) With or Without Glucagon-like Peptide-1 Receptor Agonist (GLP-1 RA) Co-therapy
The main aim of this study is to assess whether secukinumab treatment retention over 12 months in adult patients with moderate-to-severe plaque PsO receiving secukinumab in combination with a GLP-1 RA is non-inferior to that in…
- Trial name
- STAY SEC PsO (NCT07881783)
- Volunteers
- 3,718 people
- Sponsor
- Novartis Pharmaceuticals
Drug Toxicity
Regional Data Exchange to Improve Medication Safety
Medication reconciliation, a process by which a provider obtains and documents a thorough medication history with specific attention to comparing current and previous medication use, can prevent medication-related errors and…
- Trial name
- NCT01239121
- Testing
- HIE-Enhanced Medication Reconciliation, Optimal Medication Reconciliation without HIE
- Where
- United States
- Volunteers
- 402 people
- Sponsor
- VA Office of Research and Development
Polycythemia Vera (PV)
Ruxolitinib for Polycythemia Vera in Patients Resistant to or Intolerant of Hydroxyurea.
This was an analytical and descriptive, non-interventional, retrospective cohort study of PV patients aged ≥ 18 years in the US using a secondary data source, Optum EHR database.
- Trial name
- NCT05421104
- Testing
- Ruxolitinib
- Where
- United States
- Volunteers
- 1,576 people
- Sponsor
- Novartis Pharmaceuticals
Healthy
Study to Verify the Feasibility of Collecting a Broad Variety of Individual Health Data
The purpose of the OBSERVE PILOT is to verify the feasibility of collecting individual health data which is obtained through blood samples, continuous monitoring devices, medical imaging, a questionnaire, and a blood pressure…
- Trial name
- NCT03135678
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Hilbert Paradox NV
Cancer Patients With Outpatient Treatment
Remote Monitoring of Cancer Patients With Outpatient Treatment
This project focuses on studying the use of digital platforms for monitoring, between medical visits, parameters such as toxicities and therapeutic adherence.
- Trial name
- NCT06745401
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Persei Vivarium
Hyperthyroidism
Morbidity and Mortality Associated With the Care Journey in Children and Adolescents With Hyperthyroidism
"Early paediatric Basedow disease is one of the rare endocrine diseases for which the Reference Centre for Rare Endocrine Growth Diseases, was approved by the Ministry of Health in 2005.
- Trial name
- MOTHYRE (NCT03951532)
- Where
- France
- Volunteers
- 1,650 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pregnancy Related, Maternal Health
Accountability for Care Through Undoing Racism & Equity for Moms
This project-also known as "Accountability for Care through Undoing Racism \& Equity for Moms" or ACURE4Moms-aims to reduce Black-White maternal health disparities using multi-level interventions designed to decrease bias in…
- Conditions
- Pregnancy Related, Maternal Health, Maternal Mortality, Low Birthweight
- Trial name
- ACURE4Moms (NCT05484804)
- Testing
- Data Accountability and Transparency, Community-Based Doula (CBD) Support
- Where
- United States
- Volunteers
- 60,000 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Severe Mental Illness
Care Coordination and Passive Mobile Data Monitoring to Improve Mental Health Care
Providing care to individuals with serious mental illness can be challenging, requiring ongoing monitoring, treatment adjustments, and coordination of various medical and social services.
- Trial name
- CCM (NCT07549178)
- Testing
- Care Coordination Mobile
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- VA Office of Research and Development
Migraine Disorders
Potential Osteocatabolic Effect Caused by Anti-CGRP mAbs in Migraine Patients Treated With Anti-CGRP mAbs - an Observational Pilot Project With Prospectively Collected Health Related Data
Background: To gain insight on the osteoanabolic activity of anti-CGRP mAbs in patients with migraine as this was not yet specifically investigated in registration or post-approval clinical studies, however, being…
- Trial name
- NCT06035458
- Testing
- Diagnostic radiology
- Where
- Switzerland
- Volunteers
- 42 people
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona