Clinical trials: Health Disparities, open to volunteers
Chronic Low Back Pain (CLBP)
Empowering Pain Psychology Access and Collaboration (EPPAC) to Improve Treatment Engagement Among Medicaid-insured Adults With Chronic Low Back Pain
Chronic low back pain (cLBP) is a leading cause of disability, with socioeconomically disadvantaged populations experiencing worse outcomes and lower rates of treatment initiation for evidence-based pain psychology services.
- Trial name
- NCT07843706
- Testing
- Empowering Pain Psychology Access and Collaboration (EPPAC), Usual Care Pain Psychology Evaluation
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Johns Hopkins University
Breast Carcinoma, Breast Ductal Carcinoma in Situ
A Patient Navigation Program for Addressing Disparities in Breast Cancer Care
This clinical trial evaluates a patient navigation program for addressing disparities in breast cancer care. The navigation program is designed to help improve patient knowledge about clinical and supportive care services…
- Trial name
- NCT06350500
- Testing
- Patient Navigation, Questionnaire
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Roswell Park Cancer Institute
Overweight and Obesity
Optimal Digital Weight Loss Treatment for Rural Individuals
Over 130 million adults in the US experience overweight and obesity, and rural communities experience significantly higher rates of obesity and related chronic diseases.
- Trial name
- iREACH (NCT06105957)
- Testing
- Core, Facilitated Weekly Group Sessions, Counselor Crafted Feedback
- Where
- United States
- Volunteers
- 616 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Cervical Carcinoma
A Community Based Intervention to Improve Cervical Cancer Screening Among Women in the Hispanic and East African Immigrant Community
This clinical trial studies whether a community based intervention improves cervical cancer screening (CCS) among women in the Hispanic and East African immigrant community.
- Trial name
- NCT07890402
- Testing
- HPV Self-Collection, Informational Intervention, Interview
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Spinal Muscular Atrophy (SMA)
Diagnostic Journey, Patient Experience, and Disparities in the Treatment of Spinal Muscular Atrophy (SMA) in the MedStar Health System
Evaluate the diagnostic journey, patient experience, and disparities in the treatment of Spinal Muscular Atrophy (SMA) in the MedStar Health System.
- Trial name
- SMA (NCT07223489)
- Testing
- Telephone Interview
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Medstar Health Research Institute
Atrial Fibrillation (AF), Heart Failure
Somatic Health Screening for Adults in Outpatient Psychiatric Care in Denmark (SomaScreen)
People with severe mental illness have a substantially increased risk of undiagnosed and insufficiently treated somatic disease.
- Conditions
- Atrial Fibrillation (AF), Heart Failure, Asthma (Diagnosis), Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- SomaScreen (NCT07518446)
- Testing
- Somatic Health Screening for Adults in Outpatient Psychiatric Care in Denmark (SomaScreen)
- Where
- Denmark
- Volunteers
- 2,800 people
- Sponsor
- Amager Hospital
Colorectal Cancer
Choose It and Use It: Choice, Implementation Intentions and At-Home Colorectal Cancer Screening
The goal of this study is to improve use of colorectal cancer screening among screening eligible African Americans who are served by Federally Qualified Health Centers in Michigan.
- Trial name
- NCT06085560
- Testing
- Usual Care Message, Implementation Intention Intervention: Standard Message, Implementation Intention Intervention: Culturally-Targeted Message
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Dental Caries, Dry Mouth
Oral Health Intervention in Adult Primary Care
This study is a Stage III cRCT to test the efficacy of multi-level interventions at the practice- and provider-level to address low dental utilization (attendance) among Medicaid-enrolled older adults 55 years or older attending…
- Conditions
- Dental Caries, Dry Mouth, Periodontal Diseases, Bleeding Gum
- Trial name
- NCT06555029
- Testing
- EHR Changes, Medical Staff EHR Training, Clinician CSM theory-based didactic education and skills training, Standard ADA Oral Health Training
- Where
- United States
- Volunteers
- 929 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Sleep Apnea, Insomnia
Adult Sleep Health in the Rural Appalachia and Mississippi Delta Region and Its Relationships With Cardiometabolic Health Disparities.
Rural communities in the southern U.S. suffer a disproportionate burden of morbidity and mortality from cardiometabolic disease, with traditional risk factors explaining only a modest proportion of the excess burden of disease.
- Conditions
- Sleep Apnea, Insomnia, Sleep Deprivation, Sleep Disorders, Circadian Rhythm
- Trial name
- NCT06336525
- Where
- United States
- Volunteers
- 3,680 people
- Sponsor
- Brigham and Women's Hospital
Atrial Fibrillation, Coronary Heart Disease
EMPOWER-1: A Multi-site Clinical Cohort Research Study to Reduce Health Inequality
Health inequality and genetic disparity are a significant issue in the United Kingdom (UK). This study focuses on diseases that are associated with significant morbidity and mortality in the UK, and specifically examines the…
- Conditions
- Atrial Fibrillation, Coronary Heart Disease, Cardiovascular Diseases, Heart Failure
- Trial name
- EMPOWER (NCT03987633)
- Where
- United Kingdom
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- Future Genetics Limited
Obesity
Modifying Diet to Improve Gut Microbiome
The investigators will conduct a 2-arm randomized controlled pilot, feasibility feeding study in which 28 participants will be randomized to receive either a calorie-restricted Dietary Approaches to Stop Hypertension (DASH) diet…
- Trial name
- NCT03924778
- Testing
- DASH diet, standard American diet
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Hepatocellular Carcinoma, Liver Function
Effects of Vitamin D Status and Multiple Mega-dose Supplementation on Health Care Disparities in Perioperative Patients With Hepatocellular Carcinoma Receiving Hepatectomy
High concentrations of parathyroid hormone (PTH) are common in patients with hepatocellular carcinoma (HCC). This study is aimed to investigate effects of vitamin D status and its multiple mega-dosage supplementation on PTH and…
- Conditions
- Hepatocellular Carcinoma, Liver Function, Postoperative Complications
- Trial name
- NCT05887505
- Testing
- Vitamin D
- Volunteers
- 120 people
- Sponsor
- Taoyuan General Hospital
Diabetes Mellitus, Type 2
Using Remote Monitoring to Address Health Disparities in Type 2 Diabetes
Patient populations at community health centers, specifically Black or African American and Hispanic or Latino populations with Type 2 diabetes, experience significant health disparities.
- Trial name
- NCT06517576
- Testing
- Blood glucose monitor with Digital Platform and Health Coaching, Continuous glucose monitor, Usual Care
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Lawndale Christian Health Center
Diabetes
Achieving Chronic Care equiTy by leVeraging the Telehealth Ecosystem
This study examines the impact of a multi-level intervention aiming to improve telehealth access for low-income patients managing chronic health conditions, such as hypertension and diabetes.
- Trial name
- ACCTiVATE (NCT06598436)
- Testing
- Digital Health Coaching (Patient-Level Intervention), Practice Facilitation (Clinic-Level Intervention)
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- University of California, San Francisco
Prediabetes, Weight Loss
Diabetes Prevention Through Genetics, Familial History and Behavior Change
The goal of this clinical trial is to learn if adding a family engagement component to the standard Diabetes Prevention Program (DPP) improves outcomes for adults with prediabetes.
- Trial name
- NCT07815236
- Testing
- LEGACY DPP, DPP
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Morehouse School of Medicine
Breast Cancer, Hematologic Malignancy
Global Cardio Oncology Registry
G-COR is the first Global Prospective Cardio-Oncology Registry. It is a multinational, multicenter prospective observational cohort registry, with the goal of collecting clinical, laboratory, imaging, demographic, and…
- Conditions
- Breast Cancer, Hematologic Malignancy, Immune Checkpoint Inhibitor-Related Myocarditis, Cardiotoxicity
- Trial name
- G-COR (NCT05598879)
- Testing
- anonymized data collection during programmed surveillance clinical follow up
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- The Cleveland Clinic
Maternal Mortality Disparities, Maternal Morbidity Disparities
Scaling up Maternal Health Equity Best Practices
This study works with prenatal and postnatal care providers in 12 Michigan counties to scale up best practices for maternal health equity.
- Trial name
- NCT06541951
- Testing
- Services as usual, Scale-up implementation approach
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Cardiometabolic Risk Factors, Mental Health
A Natural History of Cardiometabolic Disease Among US Bhutanese: Developing the Cross-Sectional Bhutanese Community of Central Ohio Health Study to Understand Acculturation as Synergizing Socioenvironmental and Biobehavioral Risk Factors Propagating ...
Background: As of 2021, almost 45 million people in the United States were foreign-born immigrants. South Asians, including people from Bhutan, are the fastest-growing immigrant subgroup in the US.
- Trial name
- NCT06991751
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Lung Cancer, Cancer of the Lung
Evaluating the Implementation and Effectiveness of the Pink and Pearl Campaign on Lung Cancer Screening at Christian Hospital
Inspired by the ongoing Pink \& Pearl Campaign, the breast radiology service of Christian Hospital in north St. Louis County will partner with Siteman Cancer Center to pilot this campaign in its mammography clinics in order to…
- Trial name
- NCT07146568
- Testing
- Pink and Pearl Campaign
- Where
- United States
- Volunteers
- 5,515 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Opioid Use Disorder
Addressing Racial Disparities in Opioid Overdose Using Peer Recovery Coach Training and mHealth Platform
The study aims to adapt an existing Cultural Structural Humility (CSH) training into a video format for peer recovery coaches (PRCs) and refine an AI-driven texting tool to reinforce the training.
- Trial name
- NCT06573476
- Testing
- PRC supported text + AI driven CSDH-enhanced text, AI driven CSDH-enhanced text only, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Friends Research Institute, Inc.