Clinical trials: Health Options, open to volunteers
Traumatic Brain Injury
Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) Precision Medicine Phase 2 Option 1
This study is being conducted to validate early and ultra-early blood-based and novel imaging biomarkers of Diffuse Axonal Injury (DAI), Microvascular Injury (MVI), and neuroinflammation that may serve as predictive and…
- Trial name
- NCT04602806
- Where
- 5 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Francisco
Smoker, Smoking Cessation
The Options 2 Study
The goal of this clinical trial is to investigate how well nicotine pouches and nicotine mini lozenges serve as substitutes for cigarettes when people try to switch from smoking to using these alternate nicotine products.
- Trial name
- NCT06595459
- Testing
- Nicotine Pouches, Mini Nicotine lozenges
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Wisconsin, Madison
Low Back Pain, Chronic Pain (Back / Neck)
Digitally Delivered Treatments to Reduce Chronic Low Back Pain
This study aims to evaluate the effectiveness of pain education and clinical hypnosis delivered via a mobile app compared to a guideline-informed factsheet for reducing pain and disability in people experiencing chronic low back…
- Conditions
- Low Back Pain, Chronic Pain (Back / Neck), General Practice (GP), Primary Care Settings, Digital Health
- Trial name
- NOTUS (NCT06984354)
- Testing
- Pain education and clinical hypnosis delivered via a mobile app, Guideline-informed factsheet
- Where
- Australia
- Volunteers
- 720 people
- Sponsor
- Neuroscience Research Australia
Menstrual Regulation, Menstrual Health Intervention
Period Pills for Menstrual Regulation: A New Reproductive Health Option
The Period Pills Study is a prospective observational study among people who decide to use a combination of mifepristone and misoprostol for menstrual regulation.
- Trial name
- Period Pills (NCT07671989)
- Testing
- Mifepristone + Misoprostol
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Smoking Cessation
Enhancing Smoking Cessation Via Telehealth Options in Primary Care
The purpose of this research study is to evaluate an electronic visit (e-visit) for smoking cessation. Participants will be randomly assigned to receive either the smoking cessation e-visit or not.
- Trial name
- E-STOP (NCT05493254)
- Testing
- Smoking cessation e-visit, Treatment As Usual
- Where
- United States
- Volunteers
- 672 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Sarcopenic Obesity, Obesity and Obesity-related Medical Conditions
Plant vs Animal-based Protein Sources as an Anabolic and Metabolic-protective Options for SO in Older Adults
This study is testing how different types of protein - from red meat, legumes (like lentils and beans), or a mix of both - affect muscle strength, body composition, and metabolic health in older adults with obesity who are also…
- Conditions
- Sarcopenic Obesity, Obesity and Obesity-related Medical Conditions, Obesity (Body Mass Index >30 kg/m2), Sarcopenia
- Trial name
- NCT07030738
- Testing
- Legume-Based High-Protein Diet + Resistance Training, Meat-Based High-Protein Diet + Resistance Training, Mixed Legume and Meat High-Protein Diet + Resistance Training
- Where
- Israel
- Volunteers
- 180 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Sleep Apnea
Behavioral Optimization to Overcome Obstructive Sleep Apnea Treatment Barriers
Previous studies have shown that programs encouraging the use of OSA treatments can help patients use these treatments more often, but the improvement is usually modest.
- Trial name
- BOOST (NCT07207473)
- Testing
- Behavioral strategy program X plus Y, Behavioral strategy program X
- Where
- 2 sites in United States
- Volunteers
- 128 people
- Sponsor
- VA Office of Research and Development
Fertility Preservation, Cancer Remission
Long-term Evaluation of Fertility Preservation Options in Women in Cancer Remission or Haematological Pathology
Cancer treatments, despite their increasing effectiveness, carry a significant risk of gamete toxicity. Women of reproductive age are commonly offered fertility preservation (FP) before starting their treatment.
- Conditions
- Fertility Preservation, Cancer Remission, Reproductive Outcomes, Reproductive Health
- Trial name
- FERT-ISSUES (NCT07312058)
- Where
- France
- Volunteers
- 102 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
HIV Infection, Sexual and Reproductive Health
PrEPared to Choose (PtC) is an Implementation Study of the Delivery of Cabotegravir Long-acting, an Injectable Pre-exposure Prophylaxis (PrEP) Option for HIV Prevention. Injectable PrEP Will be Offered Alongside Oral and Vaginal Ring PrEP From Within a Real-world Context in Cape Town, South Africa.
The goal of this clinical trial is to offer adolescents and young people in Cape Town, South Africa different HIV pre-exposure prophylaxis (PrEP) products and describe how they use these products over an 18-month period.
- Trial name
- PtC (NCT06807736)
- Testing
- Cabotegravir long-acting, Tenofovir emtricitabine, Dapivirine containing vaginal ring
- Where
- South Africa
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Desmond Tutu HIV Foundation
Health Options, Strategic Care Planning
Communicating Health Options to Inform Care and Empower Strategic Care Planning (CHOICES): A Multi-layer Randomized Case Vignette Study.
To learn more about how the delivery of medical information affects therapy choices for participants with advanced forms of cancer.
- Trial name
- NCT06722846
- Testing
- Randomized Case Vignette Study
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- M.D. Anderson Cancer Center
Uterine Cervical Neoplasms, HPV Testing
Human Papillomavirus (HPV) Self-Sampling Options to Promote Equity
This study is testing a new way to help people who are unhoused get screened for cervical cancer. Cervical cancer can often be prevented if it is found early.
- Conditions
- Uterine Cervical Neoplasms, HPV Testing, Pap Smear
- Trial name
- HOPE (NCT07214506)
- Testing
- Human papillomavirus Self-collection, Usual Care
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Chronic Pain, Back Pain
Psychological Options for Wellness and Recovery (POWeR) Trial for Veterans With Chronic Back/Neck Pain
The goal of this clinical trial is to learn which treatment works better for veterans with chronic neck or back pain. This study is comparing three treatments: Pain Reprocessing Therapy (PRT), Cognitive Behavioral Therapy (CBT)…
- Conditions
- Chronic Pain, Back Pain, Back Pain Lower Back Chronic, Neck Pain
- Trial name
- POWeR (NCT07137715)
- Testing
- Pain reprocessing therapy (PRT), Cognitive Behavioral Therapy for Chronic Pain (CBT-CP), Usual Care
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- University of Colorado, Denver
Primary Care Patients, Primary Care Center
Testing the Impact of the MOHR Follow-up Support
This study will evaluate the impact of 3 different strategies to increase engagement of participants in My Own Health Report (MOHR) and health behavior change activities over time.
- Trial name
- NCT07569224
- Testing
- Providing reminder and resources via messages, Reminder and resources sent via navigation, Regular care
- Where
- 6 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Food Choice, Implementation Science
Healthy Options At Pantries (HOAP) Study
This study will evaluate a digital nudge intervention, Healthy Options At Pantries (HOAP), in the online food pantries of three large charitable food organizations.
- Conditions
- Food Choice, Implementation Science, Food Insecurity, Diet, Healthy
- Trial name
- HOAP (NCT07729436)
- Testing
- Behavioral economics-based Healthy Options At Pantries (HOAP) digital nudge intervention
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Communication Barriers, Language
Options for Lowering the Threshold to Brussels Out-of-hours Primary Care Services for Dutch Speaking Citizens
The purpose of this qualitative study is to find out which technological translation tools can be used to improve Dutch-speaking care in all Brussels out-of-hours primary care services.
- Conditions
- Communication Barriers, Language, Primary Health Care, After-hours Care
- Trial name
- BruWNed (NCT06700980)
- Testing
- Focus Group
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel