Clinical trials: Health Prevention
Cardiovascular Disease Prevention
Impact of a Nutritional Supplement on Metabolic Health
There are prevalent micronutrient and fiber deficiencies in a significant proportion of US population, particularly among the overweight or obese.
- Trial name
- CHORIBar (NCT02239198)
- Testing
- Nutrition bar
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Childhood Obesity
Mountain West Prevention Research Center Core Research Project
This hybrid type 3 effectiveness-implementation sequential multiple assignment randomized trial will assess the impact of integrating population health management (PHM) strategies-text messaging and enrollment in Building Healthy…
- Trial name
- MW-PRCCRP (NCT07479498)
- Testing
- Text Message-based recruitment, Active outreach follow-up
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Paul Estabrooks
Early Childhood Caries (ECC), Dental Caries Prevention
Evaluating the Effect of Xylitol Wipes on Cariogenic Bacteria in Infants and Toddlers
This clinical study evaluates whether cleaning infants' and toddlers' teeth and gums with xylitol-containing wipes can help reduce oral bacteria associated with early childhood caries.
- Conditions
- Early Childhood Caries (ECC), Dental Caries Prevention, Oral Bacterial Colonization, Pediatric Oral Health
- Trial name
- NCT07245433
- Testing
- Xylitol Dental Wipes
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Alexandria University
HIV Infections, Sexual Health
Sexual Health of Sub-Saharan African Migrant Women Recently Diagnosed With HIV in Île-de-France: Missed Opportunities for Prevention
This study looks at the sexual health of women from Sub-Saharan Africa who recently found out they have HIV after arriving in Île-de-France.
- Conditions
- HIV Infections, Sexual Health, Migrants, Women's Health
- Trial name
- NCT07011017
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Centre Hospitalier de Saint-Denis
Urinary Bladder, Overactive, Urinary Incontinence, Urge
Efficacy of Animated Videos to Foster Healthy Bladder Behaviors in Community Women
In daily life, women are exposed to a wide range of challenging situations that can negatively affect toileting management and long-term bladder health.
- Trial name
- NCT06921915
- Testing
- eLearning
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kathleen O'Connell
HIV Antiretroviral Therapy (ART) Adherence, Perinatal Mental Health
Prevention of Mother-to-child Transmission (PMTCT) Among Women Experiencing Depression in Malawi
Prevention of mother-to-child transmission (PMTCT) of HIV virtually eliminates transmission of HIV from mothers to their infants.
- Conditions
- HIV Antiretroviral Therapy (ART) Adherence, Perinatal Mental Health, Depression During Pregnancy, PMTCT
- Trial name
- NCT06659315
- Testing
- Couples Problem Solving Therapy
- Where
- Malawi
- Volunteers
- 180 people
- Sponsor
- University of California, San Francisco
Other Specified Personal Exposures and History Presenting Hazards to Health, Knowledge, Attitudes, Practice
Safe Play Areas for Ross County Kids Project
Specific Aim 1 - In collaboration with partners in Ross County, renovate and develop playgrounds in Chillicothe. Specific Aim 2 - In collaboration with partners in Ross County, promote safe play and play areas for children on…
- Conditions
- Other Specified Personal Exposures and History Presenting Hazards to Health, Knowledge, Attitudes, Practice, Fall Involving Playground Equipment, Occurrence on Farm
- Trial name
- SPARK (NCT01291225)
- Testing
- Playground renovation and development, Educational campaign
- Where
- United States
- Volunteers
- 311 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
The Focus is the Prevention and Promotion of Mental Well-being and is a Universal Delivery Intervention
Promotion of Mental Health in Adolescents: A School-Based Preventive Version of the Unified Protocol (UP-A Kind)
The goal of this clinical trial is to assess the efficacy of the Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders for Adolescents (UP-A; Ehrenreich-May et al., 2018) as a universal school-based preventive…
- Trial name
- UP-A Kind (NCT07021001)
- Testing
- UP-A, a cognitive-behavioral structured group intervention, was adapted as a universal preventive intervention to be delivered in school settings (UP-A Kind).
- Where
- Portugal
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Coimbra
Burnout, Professional, Mental Health Issue
Ambulatory Electrodermal Activity Measurements as Part of Identification and Prevention of Job Burnout
The study investigates the associations of ambulatory electrodermal activity (EDA) measurements with mental well-being at work, especially job burnout.
- Conditions
- Burnout, Professional, Mental Health Issue, Anxiety, Depression
- Trial name
- NCT05317793
- Where
- 3 sites in Finland
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Mental Health Disorder, Obesity
Improving Mental Health in Youth and Lowering Risk for Obesity Through a Digital Preventative Product
The goal of this study is to test the feasibility and utilization of a redesigned mobile app and health coaching platform (Vira) in youth (aged 18-25 years) with elevated depressive symptoms who are overweight/obese and/or…
- Conditions
- Mental Health Disorder, Obesity, Overweight
- Trial name
- NCT05638516
- Testing
- Vira mobile app intervention, Vira mobile app intervention + coaching
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Ksana Health
Musculoskeletal Manipulations, Primary Prevention
Effects of Perineal Massage (PERMAS)
Perineal massage increases elasticity of myofascial perineal tissue and decreases the burning and perineal pain during labour, thus optimizing child birth, although an application protocol has not been standardized yet.
- Conditions
- Musculoskeletal Manipulations, Primary Prevention, Obstetric Labor Complications, Physical Therapy Modalities
- Trial name
- PERMAS (NCT05114811)
- Testing
- Self-provided perineal massage, Physiotherapist perineal massage: manual and instrumental (with EPI-NO)
- Where
- Spain
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Universidad de León
Neoplasms
Alberta Cancer Exercise Hybrid Effectiveness-Implementation Study
The primary purpose of this proposed 5-year hybrid effectiveness and implementation study is to evaluate the relative benefit from, and implementation of an Alberta wide clinic-to-community-based cancer and exercise model of care…
- Trial name
- ACE (NCT02984163)
- Testing
- Exercise
- Where
- 2 sites in Canada
- Volunteers
- 2,570 people
- Sponsor
- University of Alberta
Immunization Programs
Email-based Reminders Promoting Recommended Pediatric Preventative Visits
The purpose of this study is to assess, prospectively, the effect of email reminders for well-child check (WCC) visits on adherence to these visits among those who have not yet scheduled the visit.
- Trial name
- NCT05317884
- Testing
- Reminder
- Where
- United States
- Volunteers
- 1,186 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Chronic Disease Prevention
Engaging Partners in Caring Communities
The goal of the EPICC observational study is to learn about capacity to implement evidence-based health promotion programs (EBPs) in congregations that are offered semi-structured technical assistance (TA).
- Trial name
- EPICC (NCT06932549)
- Testing
- Technical assistance is designed to integrate Expert Recommendations for Implementing Change (ERIC) strategies, and Getting To Outcomes-TA.
- Where
- United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Tennessee State University
Athletic Performance, Plyometric Exercise
A Randomized Crossover Study on Diverse Training Methods to Enhance University Athletes' Performance and Health
The goal of this randomized crossover study is to investigate the effects of plyometric training, functional training, and whole-body electrical muscle stimulation (WB-EMS) on athletic performance and health in university…
- Conditions
- Athletic Performance, Plyometric Exercise, Healthy
- Trial name
- NCT06546605
- Testing
- Whole-Body Electrical Muscle Stimulation (WB-EMS) Training, Plyometric Training, Functional Training
- Where
- 2 sites in Macau
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Macau
Substance-Related Disorders, Sexually Transmitted Diseases
Adolescent Drug and HIV Prevention in South Africa
The purpose of this trial is to test the effectiveness of a classroom-based prevention program (HealthWise: Learning Life Skills for Young Adults) to reduce the risk of HIV/AIDS and STIs, as well as substance use, among…
- Trial name
- NCT00336180
- Testing
- HealthWise South Africa curriculum
- Where
- South Africa
- Volunteers
- 7,695 people, healthy volunteers welcome
- Sponsor
- Penn State University
Breast Cancer Prevention
MELIORA Virtual Coach Intervention for Breast Cancer Prevention
Breast cancer (BC) is the most commonly diagnosed cancer in women worldwide, with early-onset cases increasing due to genetic and lifestyle factors.
- Trial name
- MELIORA (NCT07200427)
- Testing
- MELIORA Virtual Coach Intervention, Control (generic advice)
- Where
- 7 sites in Greece, Lithuania and 2 more
- Volunteers
- 2,080 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Adenoma of Large Intestine
Folic Acid in Preventing Colorectal Polyps in Patients With Previous Colorectal Polyps
RATIONALE: Chemoprevention is the use of certain substances to keep cancer from forming. The use of folic acid may prevent colorectal cancer.
- Trial name
- NCT00512850
- Testing
- Folic acid
- Volunteers
- 672 people
- Sponsor
- Brigham and Women's Hospital
HIV Infections, Risk Reduction
Seroincidence Study Among Men Who Have Sex With Men and Transgender Women - The ImPrEP Seroincidence Study
PrEP (pre-exposure prophylaxis) is an effective prevention strategy in which HIV-negative individuals take antiretroviral drugs (tenofovir disoproxil fumarate and emtricitabine - TDF/FTC) to reduce HIV acquisition.
- Conditions
- HIV Infections, Risk Reduction, Risk Behavior, Risky Health Behavior
- Trial name
- Seroincidence (NCT05674682)
- Testing
- HIV testing
- Where
- 2 sites in Brazil
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Evandro Chagas National Institute of Infectious Disease
Mental Health
Gender Microagression Psychoeducation
Objective: This study evaluates the effectiveness of the Gender-Based Microaggression Awareness and Prevention Psychoeducation Program, which was designed to enhance awareness of gender-based microaggressions among female…
- Trial name
- NCT07120360
- Testing
- Gender-Based Microaggression Awareness and Prevention Psychoeducation Program
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
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