Clinical trials: Health Prevention
Type 2 Diabetes Mellitus
Tertiary Prevention in Type II Diabetes Mellitus in Canary Islands Study
Objective: To improve health outcomes of patients with type 2 diabetes mellitus (T2DM) by influencing disease self-management through lifestyle modification and by helping primary care professionals to improve health care…
- Trial name
- INDICA (NCT01657227)
- Testing
- Intervention to patients, Intervention to professionals, Usual care
- Where
- Spain
- Volunteers
- 2,334 people
- Sponsor
- Servicio Canario de Salud
Cognitive Dysfunction, Alzheimer Disease
ALA-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older Adults
This randomized, double-blind, placebo-controlled pilot trial will evaluate the effects of alpha-linolenic acid (ALA) supplementation on cognitive function, blood-brain barrier integrity, and brain vascular health in older adults…
- Conditions
- Cognitive Dysfunction, Alzheimer Disease, Blood-Brain Barrier, Apolipoprotein E, Deficiency or Defect of
- Trial name
- NCT07392723
- Testing
- Alpha-Linolenic Acid (2.6 g/day)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Michal Schnaider Beeri, Ph.D.
Asperger's Disorder, Asperger Disorder
QAIAx - SGI/SI Smart Health Cities: Microcity Enclave Program (Quantum SI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428, 64/125,360; USPTO EO 9424 Assignment ID: 2101042 / ARN: REEL/FRAME: 76481/0026 - OUSD-R&E, Department of War)
BRIEF SUMMARY A. "What is the purpose of this study?" BACKGROUND. The QAIAx clinical trial (Quantum SI/SGI Public Health Agency), known operationally as the "AI City Hall Project," represents a landmark intergovernmental research…
- Conditions
- Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism
- Trial name
- QAIAx (NCT07661823)
- Testing
- AI City Hall Project (AIhealth4u - Public Health Central), AI City Hall Project (QAIAx Microcity A - AI Public Health Central)
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Veterans Recovery Network Inc.
Health and Wellbeing of Primary School-aged Children
Healthy Childcare Centre of the Future
Rationale: In 2015-2020, the Dutch 'Healthy Primary School of the Future' intervention took place. Two schools became 'Healthy Primary Schools of the Future'; providing a healthy lunch and structured physical activity (PA)…
- Trial name
- HCCF (NCT04193410)
- Testing
- Various health-promoting initiatives
- Where
- Netherlands
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Obesity
Pregnancy-Related Obesity Prevention Through Education & Communication Technology in AFRICA:The PROTECT-AFRICA STUDY
The purpose of this study is to investigate whether overweight but not obese pregnant African women having unlimited access to a health education-information technology (IT) based intervention package gain weight within the…
- Trial name
- PROTECT-AFRI (NCT01948323)
- Testing
- HEDUAfrica IT package+ standard care
- Where
- 2 sites in South Africa
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Cape Town
Suicidal Ideation, Suicidal Behavior
App-based Intervention to Promote Mental Health Help-seeking Among University Students
It is estimated that approximately one in three university students has a mental health problem and between 5-10% have active suicidal ideation.
- Trial name
- NCT05770388
- Testing
- App Take Care of Your Mood, Reminder messages and counseling
- Where
- Chile
- Volunteers
- 60 people
- Sponsor
- University of Chile
Drug Use, Pre-exposure Prophylaxis (PrEP)
Pre-exposure Prophylaxis (PrEP) Rapid Access
The goal of phase 1 is to determine the feasibility and acceptability of an intervention ('Rapid PrEP Access') providing people who use drugs (PWUD) one-time access to HIV self-testing at the Victory Program.
- Conditions
- Drug Use, Pre-exposure Prophylaxis (PrEP), Opioid Use Disorder
- Trial name
- NCT05528562
- Testing
- PrEP Rapid Access, HIV self-testing, Dried blood spot testing
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Boston Medical Center
Human Immunodeficiency Virus
Evaluation of Problem Management Plus in Pregnant Women With HIV in Kenya
This study includes secondary quantitative analysis, qualitative methods, and hybrid type 2 implementation-effectiveness pilot trial.
- Trial name
- Tatua (NCT05841797)
- Testing
- In-Person Program Management Plus (PM+), Mobile Program Management Plus (mHealth PM+)
- Where
- Kenya
- Volunteers
- 120 people
- Sponsor
- University of Colorado, Denver
Cardiovascular Diseases, Cardiovascular Risk Factor
Digital Nudges to Improve Heart Health Actions After Community Screening in Malaysia (NADI-MyHeartRisk)
This is a pragmatic, risk-stratified, individually randomized controlled trial testing whether personalised WhatsApp-based digital behavioural nudges can improve completion of cardiovascular preventive actions after community…
- Trial name
- NADI-MHR (NCT07879144)
- Testing
- Personalised Digital Behavioural Nudges (NADI-MyHeartRisk Enhanced Pathway)
- Where
- 2 sites in Malaysia
- Volunteers
- 6,588 people, healthy volunteers welcome
- Sponsor
- Cardiovascular Advancement and Research Excellence Institute
Binge Alcohol Consumption, Risk Behavior, Health
A Family-Based Alcohol Preventive Intervention for Latino Emerging Adults
The purpose of the proposed study was to develop a family-based drinking prevention intervention for Latino emerging adults (EAs) and Latino parents of EAs.
- Conditions
- Binge Alcohol Consumption, Risk Behavior, Health, Driving Under the Influence, High-Risk Sex
- Trial name
- LEA (NCT05437081)
- Testing
- Latino Emerging Adults (LEA)
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Venous Thromboembolism, Digital Health
Smart Technology Facilitated Patient-centered Venous Thromboembolism Management
Smart technologies, such as wearable devices, mobile technologies, and artificial intelligence, are being investigated for use in health management.
- Conditions
- Venous Thromboembolism, Digital Health, Health Education
- Trial name
- SmaVTE-COR (NCT06350344)
- Testing
- mobile venous thromboembolism application (mVTEA)
- Where
- China
- Volunteers
- 2,353 people
- Sponsor
- Navy General Hospital, Beijing
Coronary Heart Disease
Feasibility of Innovative Approaches for Personalized Cardiovascular Prevention
The goal of the FITPREV (Feasibility of InnovaTive approaches for personalized cardiovascular PREVention: randomized controlled pilot trial and multidisciplinary evaluation for National Health Service implementation) clinical…
- Trial name
- FITPREV (NCT06911294)
- Testing
- Polygenic Risk Score, Digital app and wearable device
- Where
- 7 sites in Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Adolescent Behavior, Contraception
Using the Connect: Game Based Intervention
The study aims to implement Using the Connect (UTC), an innovative, game-based intervention designed to increase protective factors and decrease adolescent pregnancies.
- Conditions
- Adolescent Behavior, Contraception, Health Behavior
- Trial name
- UTC (NCT05927194)
- Testing
- Using the Connect
- Where
- United States
- Volunteers
- 1,400 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Pregnancy, Periodontal Disease
Lactoferrin-Based Oral Care for Periodontal Health in Pregnancy
This randomized controlled clinical trial aims to evaluate the effectiveness of a lactoferrin-based oral hygiene protocol in improving periodontal health during pregnancy.
- Conditions
- Pregnancy, Periodontal Disease, Gingivitis, Oral Microbiota
- Trial name
- LBC-PREG (NCT07069140)
- Testing
- Lactoferrin-based Toothpaste and Mouthwash (Emoform Glic), Lactoferrin-Based Toothpaste Only (Emoform Glic)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Pavia
Healthy Older Adults in the Community
The Application of Inspiratory Muscle Training in Community-Dwelling Older Adults
Background: As individuals age, they experience a decline in muscle strength, particularly the respiratory muscles (such as the diaphragm), which not only affects respiratory efficiency but also may lead to postural instability…
- Trial name
- NCT07713589
- Testing
- IMT, Triflow
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hungkuang University
Cardiovascular Disease Prevention
Effects of a Smartphone-Supported Daily Walking Intervention on Psychological Well-Being and Body Composition in Adults With Cardiometabolic Disease
This study evaluated whether a three-month smartphone-supported daily walking intervention could improve physical activity, psychological well-being, and body composition in adults with cardiometabolic disease.
- Trial name
- DAILY-WALK (NCT07674459)
- Testing
- Smartphone-Supported Daily Walking
- Where
- Lithuania
- Volunteers
- 419 people
- Sponsor
- Klaipėda University
HIV/AIDS
PHAT Life: Peer Versus Adult-Led HIV Prevention for Juvenile Offenders
This application proposes a 2-arm randomized controlled trial comparing the impact of PHAT Life on 350 13-17 year-old offenders' risky sex, STI, substance use, and theoretical mediators when delivered by Youth Representatives…
- Trial name
- PHATLife (NCT03555279)
- Testing
- PHAT Life: Preventing HIV/AIDS Among Teens--PS Arm, PHAT Life: Preventing HIV/AIDS Among Teens--YR Arm
- Where
- United States
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Sexually Transmitted Infection (STI) Prevention, Unintended Pregnancy Prevention
Preventing Health Damaging Behaviors in Male and Female Army Recruits
Health damaging (risk) behaviors of young military personnel are reflections of health problems facing all young people in the U.S.
- Conditions
- Sexually Transmitted Infection (STI) Prevention, Unintended Pregnancy Prevention, Sexual Risk Reduction, Alcohol and Other Substance Use Prevention
- Trial name
- NCT01234103
- Testing
- Preventing Helath Damaging Health Behaviors in Male and Female Army Recruits
- Where
- United States
- Volunteers
- 933 people, healthy volunteers welcome
- Sponsor
- United States Department of Defense
Health Status, Stress
Health Status and Cardiovascular Stress of Veteran Soccer Players
This study shall provide missing descriptive data on health status of veteran players and potential preventive effects of soccer at an age of 40 to 60 years.
- Trial name
- NCT01171222
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universität des Saarlandes
HIV Infections
A Study of Retrovir in the Prevention of HIV Infection in Health Care Workers Accidentally Exposed to the Virus
To evaluate the safety and effectiveness of Retrovir (AZT) when used as prophylaxis for health care workers at risk for HIV infection from exposure to HIV-contaminated blood or blood components.
- Trial name
- NCT00002287
- Testing
- Zidovudine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Glaxo Wellcome
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