Clinical trials: Health Prevention
Fall Related Injury, Social Isolation
KOSO (Keep On Stepping On)/ Stepping Online
The overall purpose of this multi-phase study is to develop (Phase 1) and test potential effectiveness and feasibility of Keep On Stepping On (KOSO)/Stepping Online, an online falls prevention maintenance program for Stepping On…
- Trial name
- NCT02774889
- Testing
- Stepping Online
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Human Immunodeficiency Virus, Mental Health
Digital Star: HIV Prevention for Youth in Mental Health Treatment
Teenagers in mental health treatment are at greater risk for HIV and other sexually transmitted infections. This greater risk comes from many factors, some of which are related to poor emotion regulation and low self-confidence.
- Trial name
- DSTAR (NCT02921841)
- Testing
- D*STAR, D*HEALTH
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Rhode Island Hospital
Coronary Heart Disease
Family Heart Health Program: Randomized, Controlled Trial
Background: Family members (spouses, siblings, offspring) of patients with coronary heart disease (CHD) may themselves be at increased risk for developing CHD for genetic, biochemical and/or behavioural reasons.
- Trial name
- FHHP-RCT (NCT00552591)
- Testing
- 12-week risk reduction program, managed by a Heart Health Educator
- Where
- Canada
- Volunteers
- 426 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation
HIV Prevention, PrEP Uptake
Social Media Based Peer-Led Intervention for HIV Prevention
The purpose of this study is to test the feasibility, acceptability, and preliminary efficacy of E-PrEP on reaching young men of color who have sex with men (YMCSM) at high-risk of HIV infection to reduce HIV acquisition.
- Trial name
- NCT03213366
- Testing
- E-PrEP- Peer-Led Intervention about PrEP, BxNow - General Health Campaign
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Health Knowledge, Attitudes, Practice
Utilizing Technology to Promote Cancer Prevention
The goal of the program is to develop an online module/a health application for cell phones which will share didactic information regarding cancer prevention and early detection measures.
- Trial name
- NCT03810053
- Testing
- Mobile App/Online Module
- Where
- United States
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Wellbeing, Mental Disorder
App-based Mental Health Promotion in Young European Adults
The ECoWeB Project aims to develop and disseminate a mobile application (App) to provide engaging and personalized tools and psychological skills to promote emotional wellbeing and prevent mental health problems in adolescents…
- Trial name
- ECoWeB (NCT04148508)
- Testing
- Tailored Emotional Competence Self-help, Cognitive-behavioural Approach, Self-monitoring
- Where
- 4 sites in Belgium, Germany and 2 more
- Volunteers
- 3,794 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Nicotine Dependence
Effectiveness of GSK598809, a Selective D3 Antagonist, Added to CBT and NRT for Smoking Cessation and Relapse Prevention
The purpose of this research study is to find out if an investigational drug, GSK598809 can help people who have very recently quit smoking; the investigators want to find out if continuing to take GSK598809 over six weeks can…
- Trial name
- NCT01188967
- Testing
- GSK598809
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Massachusetts General Hospital
COVID-19
Efficacy of Hydroxychloroquine Prophylaxis for Health Care Workers at High Risk for COVID-19
The HCW Prophylaxis (HCWP) Study, single, open and off label intervention study. Up to 350 participants will be assigned to group that takes HCQ or group that opts to not take study medication.
- Trial name
- NCT04435808
- Testing
- Hydroxychloroquine
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Treatment Adherence and Compliance
PrEP iT! Mobile App Intervention
The long-term goal of this research is to create an effective and sustainable program to support retention in PrEP care and PrEP adherence among 18-29 year old men who have sex with men (MSM).
- Trial name
- PrEP iT! (NCT04509076)
- Testing
- PrEP iT! (plus usual PrEP care), Usual PrEP care
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Health and Wellbeing of Primary School-aged Children
Healthy Childcare Centre of the Future
Rationale: In 2015-2020, the Dutch 'Healthy Primary School of the Future' intervention took place. Two schools became 'Healthy Primary Schools of the Future'; providing a healthy lunch and structured physical activity (PA)…
- Trial name
- HCCF (NCT04193410)
- Testing
- Various health-promoting initiatives
- Where
- Netherlands
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Sexually Transmitted Infection (STI) Prevention, Unintended Pregnancy Prevention
Preventing Health Damaging Behaviors in Male and Female Army Recruits
Health damaging (risk) behaviors of young military personnel are reflections of health problems facing all young people in the U.S.
- Conditions
- Sexually Transmitted Infection (STI) Prevention, Unintended Pregnancy Prevention, Sexual Risk Reduction, Alcohol and Other Substance Use Prevention
- Trial name
- NCT01234103
- Testing
- Preventing Helath Damaging Health Behaviors in Male and Female Army Recruits
- Where
- United States
- Volunteers
- 933 people, healthy volunteers welcome
- Sponsor
- United States Department of Defense
Obesity, Activity, Motor
Healthy Juntos Pilot Study
The purpose of the study is to assess the feasibility, acceptability, and preliminary effects of a digital (web and mobile phone-based) program to improve physical activity levels and quality dietary intake among Hispanic…
- Conditions
- Obesity, Activity, Motor, Diet, Healthy, Sedentary Behavior
- Trial name
- NCT03986190
- Testing
- Healthy Juntos
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Miami
Acute Myocardial Infarction, Coronary Artery Disease
Myocardial Infarction, COmbined-device, Recovery Enhancement Study
Unplanned readmissions after hospitalization for acute myocardial infarction (AMI) are among the leading causes of preventable morbidity, mortality, and healthcare costs.
- Conditions
- Acute Myocardial Infarction, Coronary Artery Disease, Acute Coronary Syndrome, Myocardial Infarction
- Trial name
- MiCORE (NCT03760796)
- Testing
- Corrie Health Digital Platform
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Johns Hopkins University
Type 2 Diabetes, Pre-Diabetes
Power-Up: An Effectiveness Trial of the Diabetes Prevention Program
The goal of this study is to address the risk of diabetes among men by creating a Diabetes Prevention Program (DPP) tailored to men.
- Trial name
- Power-Up (NCT04104243)
- Testing
- Men-Tailored DPP (Power-Up)
- Where
- United States
- Volunteers
- 301 people
- Sponsor
- Albert Einstein College of Medicine
Adherence, Patient, Pre-Exposure Prophylaxis
mHealth Technologies to Enhance PrEP Adherence Among Thai MSM
This study aims to: 1) adapt the theory-based P3 (Prepared, Protected, emPowered) app designed to improve pre-exposure prophylaxis (PrEP) adherence, retention in PrEP clinical care, and PrEP persistence among young gay, bisexual…
- Conditions
- Adherence, Patient, Pre-Exposure Prophylaxis, HIV/AIDS
- Trial name
- P3-T (NCT04413708)
- Testing
- P3-T PrEP Adherence App
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Duke University
Pediatric Obesity
Healthy Eating for My Infant (HEMI)
Infants from underserved and minority backgrounds are at increased risk for obesity and poor feeding and nutrition outcomes, but obesity prevention programs tailored specifically to the needs of these infants are lacking.
- Trial name
- NCT04977947
- Testing
- Healthy Eating for My Infant
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Alcohol Dependence
Mindfulness Meditation for Health
The purpose of this 52-week clinical trial is to see if the meditation-based intervention, adjunctive to standard of care therapy, can reduce relapse and improve psychological health among adults recovering from alcohol…
- Trial name
- NCT01056484
- Testing
- Mindfulness Based Relapse Prevention for Alcohol Dependence, "Wait-list" control
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- University of Wisconsin, Madison
Smoking Cessation, Pregnancy
Phone-Based Postpartum Continuing Care for Smoking Cessation
Smoking is a leading cause of death and other negative health outcomes. While a high percentage of women quit smoking during pregnancy, the majority relapse in the first 6 months postpartum.
- Trial name
- PPCC (NCT01684592)
- Testing
- Phone-based postpartum continuing care, Standard care
- Where
- 2 sites in United States
- Volunteers
- 130 people
- Sponsor
- Battelle Memorial Institute
Refugee Self-reliance, Mental Health Issue
GBV Prevention, Mitigation, and Response in Colombia
As of August 2021, Colombia hosts the vast majority of Venezuelan refugees and migrants (UNHCR, 2022). For vulnerable refugees and migrants in Colombia, and especially for women, gender-based violence (GBV) is present during…
- Conditions
- Refugee Self-reliance, Mental Health Issue, Empowerment, Gender Based Violence Knowledge and Perceived Risk
- Trial name
- NCT06312592
- Testing
- Entrepreneurship School with Gender Lens
- Where
- Colombia
- Volunteers
- 253 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Contraceptive Behavior
Meaningful Use of Technology to Improve Health Care Delivery
While there have been major declines in teenage pregnancy around the country, Baltimore, Maryland has continued to experience increases over the last several years.
- Trial name
- DepoText (NCT01641380)
- Testing
- Text Messaging Intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University