Clinical trials: Health Prevention
Vulnerable Population
Evaluation of the Acceptability and Impact of a Sexual Health Screening and Prevention Program for Vulnerable Women
Globally, women accounted for more than half of people living with HIV (53%) in 2022. In France, 54% of new infections were heterosexual in 2022, 71% of whom were born abroad, mainly in sub-Saharan Africa (74%).
- Trial name
- PrEVE (NCT06996938)
- Testing
- Rapid diagnostic orientation tests (TROD) HIV, Hepatitis, syphilis
- Where
- 2 sites in France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Centre de Recherches et d'Etude sur la Pathologie Tropicale et le Sida
HIV, Pregnancy
Kenya Enhanced Mentor Mother ProgrAm (EMMA)
Kenya recently adopted new treatment guidelines for pregnant women with HIV, which calls for all women to initiate triple-drug antiretroviral therapy (ART) at or soon after their first visit for antenatal care.
- Trial name
- NCT02848235
- Testing
- Standard of Care + EMMA
- Where
- 12 sites in Kenya
- Volunteers
- 363 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Occupational Stress, Work-Related Stress
XR2ESILIENCE - XR-Based Resilience Training for Stress and Mental Health in Healthcare Workers
This study investigates the effectiveness of an extended reality (XR) based resilience training program designed to support the mental health and well-being of nurses working in hospital settings.
- Conditions
- Occupational Stress, Work-Related Stress, Mental Health, Burnout
- Trial name
- XR2ESILIENCE (NCT07544498)
- Testing
- XR-based Resilience Training, Waitlist Control
- Where
- 8 sites in Austria, Croatia and 3 more
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Grief, Mental Health
Effectiveness of an Internet-Based Self-Management Program in Treating Prolonged Grief Disorder
This study will evaluate the effectiveness of an Internet-based self-help program in treating people who are at risk for developing prolonged grief disorder following a recent loss.
- Trial name
- NCT00598884
- Testing
- Internet-Based Self-Management for Prolonged Grief Symptoms
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Boston University
Overdose
A Universal Primary Care Based Intervention to Reduce Youth Overdose Risk Aim 3
Between 2015 and 2019, overdose deaths translated to 1.25 million years of life lost among adolescents and young adults (youth) aged 12 to 24 years, and the percent change in fatal overdose rates among adolescents ages 14 to 18…
- Trial name
- NCT07797933
- Testing
- Brief youth overdose prevention education, Usual Standard of Care
- Where
- United States
- Volunteers
- 648 people
- Sponsor
- Boston Medical Center
Cardiovascular Diseases (CVD)
Data Donation Model for Inclusive Cardiovascular Prevention Using the TRAIN Health Platform
Cardiovascular disease (CVD) is the leading cause of death in the Netherlands and worldwide. While prevention strategies have improved, many population groups, including women, individuals with a migration background, and people…
- Trial name
- DDM-TRAIN (NCT07238036)
- Testing
- Digital Lifestyle Feedback Module (optional)
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Pediatric Obesity
Healthy Eating for My Infant (HEMI)
Infants from underserved and minority backgrounds are at increased risk for obesity and poor feeding and nutrition outcomes, but obesity prevention programs tailored specifically to the needs of these infants are lacking.
- Trial name
- NCT04977947
- Testing
- Healthy Eating for My Infant
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Type-2 Diabetes, Cardiovascular Diseases
Feasibility of a Preventive Program Against Lifestyle Related Diseases
The continuously increasing prevalence of cardiovascular diseases, type-2 diabetes, and COPD is a major health problem in developed countries and is mainly caused by an unhealthy lifestyle.
- Conditions
- Type-2 Diabetes, Cardiovascular Diseases, Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- NCT02797392
- Testing
- Lifestyle intervention
- Where
- 6 sites in Denmark, Norway and 1 more
- Volunteers
- 9,400 people
- Sponsor
- University of Southern Denmark
Coronary Heart Disease, Stroke
Evaluating Tools for Health Promotion and Disease Prevention
The study will evaluate the effect of familial risk assessment and prevention prompts tailored to familial risk on health behaviors and use of preventive services among adults who are members of primary care practices in the U.S.
- Conditions
- Coronary Heart Disease, Stroke, Diabetes, Breast Cancer
- Trial name
- NCT00164658
- Testing
- Familial risk assessment and personalized prevention messages
- Where
- 3 sites in United States
- Volunteers
- 8,400 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Behavior, Eating
Menu to Meal (M2M) Menu Labeling Intervention Study
This study evaluates the impact of culturally tailored menu labeling interventions on psychosocial factors and ordering behavior among customers in two independently owned Hispanic restaurants in East-Central Texas.
- Trial name
- NCT07329452
- Testing
- Paper menu, Digital menu condition
- Where
- United States
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Alcohol Dependence
Mindfulness Meditation for Health
The purpose of this 52-week clinical trial is to see if the meditation-based intervention, adjunctive to standard of care therapy, can reduce relapse and improve psychological health among adults recovering from alcohol…
- Trial name
- NCT01056484
- Testing
- Mindfulness Based Relapse Prevention for Alcohol Dependence, "Wait-list" control
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- University of Wisconsin, Madison
Suicidal Ideation
Improving Caregivers' Ability to Manage Life Stress
The COVID-19 pandemic has led to increased caregiving demands for caregivers of Veterans with dementia. Dementia caregivers are particularly at-risk for depression and anxiety, known risk factors for increased suicidality.
- Trial name
- NCT05539352
- Testing
- Problem Solving Therapy (PST) plus EUC
- Where
- United States
- Sponsor
- VA Office of Research and Development
Smoking Cessation, Pregnancy
Phone-Based Postpartum Continuing Care for Smoking Cessation
Smoking is a leading cause of death and other negative health outcomes. While a high percentage of women quit smoking during pregnancy, the majority relapse in the first 6 months postpartum.
- Trial name
- PPCC (NCT01684592)
- Testing
- Phone-based postpartum continuing care, Standard care
- Where
- 2 sites in United States
- Volunteers
- 130 people
- Sponsor
- Battelle Memorial Institute
Health Behavior, Motor Activity
Healthy Habits Program for High Cardiovascular Risk Patients: Randomized Controlled Clinical Trial
The purpose of this study is to determine the effectiveness of a program to improve habits in a population with cardiovascular disease, comparing two different educational techniques (cognitive behavioral therapy group vs.
- Conditions
- Health Behavior, Motor Activity, Food Habits
- Trial name
- NCT01861977
- Testing
- Cognitive Behavioral Therapy, Informational Workshop
- Where
- Argentina
- Volunteers
- 101 people
- Sponsor
- Hospital Italiano de Buenos Aires
Chronic Coronary Syndrome
Telemonitoring System for Improving Continuity of Care in Patients With Chronic Coronary Syndrome (TELSINCORC)
In a randomized clinical trial, a comprehensive telerehabilitation system with a prolonged follow-up strategy demonstrated superiority over a control group with centre-based cardiac rehabilitation in terms of physical activity…
- Trial name
- TELSINCORC (NCT05875311)
- Testing
- telemonitoring, control follow-up
- Where
- Spain
- Volunteers
- 160 people
- Sponsor
- Catcronic Salut SL
Cardiovascular Diseases, Prevention
Cardiovascular Health Promotion Among African-Americans by FAITH!
Given the importance of healthy lifestyle practices to cardiovascular disease (CVD) prevention and the utility of church-based interventions in African-American adults, the investigators developed a theory-informed…
- Conditions
- Cardiovascular Diseases, Prevention, Physical Activity, Diet Modification
- Trial name
- FAITH! (NCT03084822)
- Testing
- FAITH! App digital intervention
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Prevent Disorders in Children Adopted From Foster Care
Adoption-specific Treatment Prevention Pilot Trial
This study seeks to pilot a manualized adoption-specific intervention aimed at providing a preventive intervention for families adopting children ages 5-14 years where family reunification has been terminated and the family is…
- Trial name
- ADAPT (NCT01744951)
- Testing
- ADAPT
- Where
- 5 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Well-Being, Psychological, Work Injury
Eastern Principles Acceptance and Commitment Therapy For Injury Prevention Among Nurses and Nursing Aides
This clinical trial will evaluate the effectivness of an Eastern Principles Acceptance and Commitment Therapy intervention (EPACT) relative to an estabished traditional Western-based Acceptance and Commitment Therapy intervention…
- Conditions
- Well-Being, Psychological, Work Injury, Musculoskeletal Pain, High Frequency Heart Rate Variability
- Trial name
- NCT06813495
- Testing
- Eastern Principles Acceptance and Commitment Therapy for Nurses and Nursing Aids (EPACT NNA), Acceptance and Commitment Therapy for Nurses and Nursing Aids (ACT NNA)
- Where
- United States
- Volunteers
- 255 people
- Sponsor
- Bowling Green State University
Refugee Self-reliance, Mental Health Issue
GBV Prevention, Mitigation, and Response in Colombia
As of August 2021, Colombia hosts the vast majority of Venezuelan refugees and migrants (UNHCR, 2022). For vulnerable refugees and migrants in Colombia, and especially for women, gender-based violence (GBV) is present during…
- Conditions
- Refugee Self-reliance, Mental Health Issue, Empowerment, Gender Based Violence Knowledge and Perceived Risk
- Trial name
- NCT06312592
- Testing
- Entrepreneurship School with Gender Lens
- Where
- Colombia
- Volunteers
- 253 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Depression, Depressive Disorder
Evaluation of the Naturalistic User Experience of the Website "ich Bin Alles @Schule" (i Am Everything @school)
The aim of this study is to investigate the naturalistic user experience and acceptance of the German website "ich bin alles @Schule".
- Conditions
- Depression, Depressive Disorder, Depression in Children, Depression in Adolescence
- Trial name
- NCT06668688
- Testing
- "ich bin alles @Schule" (i am everything @school; www.schule.ich-bin-alles.de)
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
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