Clinical trials: Health Prevention
COVID19, Sars-CoV2
Assessment of the Efficacy and Safety of (HCQ) as a Prophylaxis for COVID19 for Health Professionals
Assessment of the Efficacy and Safety of Hydroxychloroquine (HCQ) Administered as a Prophylaxis for Health Professionals Exposed to COVID19 and Working in Medical Intensive Care Units, in Tunisia.
- Conditions
- COVID19, Sars-CoV2, Hydroxychloroquine, Prophylaxis
- Trial name
- COVID_2Pro (NCT04349228)
- Testing
- Hydroxychloroquine (HCQ)
- Where
- Tunisia
- Volunteers
- healthy volunteers welcome
- Sponsor
- Abderrahmane Mami Hospital
Smoking Cessation
Bio-behavioral Lung Cancer Prevention Program
The overall goal of this research is to increase our understanding of the role of individual genetic differences in response to bupropion treatment and the psychobiological mechanisms by which genetic and treatment factors…
- Trial name
- NCT00322205
- Testing
- zyban
- Where
- United States
- Volunteers
- 555 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health (NIH)
Kidney Calculi, Nephrolithiasis
Patient Compliance for Metabolic Evaluation and Medical Management in Calcium Stone Patients
Calcium oxalate stone, the most common type worldwide, has a recurrence rate of around 50% in ten years. Therefore, identifying the underlying pathophysiological aspects via metabolic evaluation and suggestions for medical \&…
- Conditions
- Kidney Calculi, Nephrolithiasis, Patient Compliance, Calcium Oxalate Urolithiasis
- Trial name
- NCT04169165
- Volunteers
- 500 people
- Sponsor
- EULIS Colloborative Research Working Group
Obesity
Family Nutrition Physical Activity Tool Use During Well Child Visits
The main aim of the study would be to examine the effect of using a health behavior screening tool and a brief patient centered conversation on health behavior goal setting during well-child visits.
- Trial name
- FNPA (NCT02067728)
- Testing
- FNPA tool, Usual Care
- Where
- United States
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Diabetes
Evaluating the Implementation of the Diabetes Prevention Program in an Integrated Health System
In preparation for the roll out of the Medicare Diabetes Prevention Program (DPP) in 2018, Kaiser Permanente Northwest (KPNW), a large, integrated health care system, plans to pilot the implementation of DPP starting in April…
- Trial name
- NCT03249077
- Testing
- Digital DPP, In-person DPP, DPP not enrolled
- Where
- United States
- Volunteers
- 8,198 people
- Sponsor
- Kaiser Permanente
Cleft Lip, Cleft Palate
Oral Cleft Prevention Trial in Brazil
Cleft lip and palate are a significant component of morbid human birth defects in the developing world. By supplementing a high-risk group of women with folic acid (4.0 mg versus 0.4 mg) from preconception and continuing…
- Trial name
- NCT00098319
- Testing
- Folic acid (0.4mg vs. 4.0mg)
- Where
- 3 sites in Brazil
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
HIV Prevention, Sexual Health
Prepping for The Talk: Helping Trusted Adults and Youth Talk About Sexual Health
The goal of this study is to help young people talk to trusted adults (including their parents, but also other adults) about sexual health more openly and honestly- including how to prevent sexually transmitted diseases like HIV…
- Trial name
- NCT07011563
- Testing
- Intervention, Control
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Delirium
A Research Study to Evaluate the Effectiveness of Dexmedetomidine in Preventing Delirium After Heart Surgery
The purpose of this study is to evaluate the efficacy and safety of dexmedetomidine in the prevention of postoperative delirium in subjects undergoing heart valve surgery with or without coronary artery bypass surgery (CABG)…
- Trial name
- NCT00464763
- Testing
- Dexmedetomidine
- Where
- 11 sites in United States
- Sponsor
- Hospira, now a wholly owned subsidiary of Pfizer
Respiratory Tract Infections
Prevention of Respiratory Infections Among Children Under 3 Years of Age Attending Daycare Centres
The aim of this study is to evaluate the influence of Primary and Secondary Prevention of Respiratory Infections in children up to 3 years-old attending daycare.
- Trial name
- PRICAD (NCT02588963)
- Testing
- Health education session, Nasal clearance Protocol, Control
- Where
- Portugal
- Volunteers
- 200 people
- Sponsor
- Polytechnic Institute of Porto
Gingivitis, Gingivitis; Chronic
A Multicentre Randomised Controlled Trial Evaluating the Efficacy of the SMILE™ Module for Improving Short-term Periodontal Outcomes, Compliance, and Acceptability Among Clinical Dental Students
This multicentre randomised controlled trial aims to evaluate the efficacy and safety of the SMILETM (Siwak Method for Integrated Lifestyle Enhancement) module in improving short-term periodontal outcomes, oral hygiene behaviour…
- Trial name
- SMILE (NCT07702383)
- Testing
- SMILE Module, Conventional Toothbrushing Module
- Where
- 4 sites in Malaysia
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Subjective Cognitive Decline (SCD)
Personalized Brain Health Service and Dementia Prevention
This study evaluates the feasibility of implementing a Brain Health Service (BHS) to assess and reduce dementia risk in individuals with Subjective Cognitive Decline (SCD).
- Trial name
- B-HEALTH (NCT07698431)
- Testing
- Multimodal Lifestyle Intervention, Lifestyle Recommendations and Counseling
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Barcelonabeta Brain Research Center, Pasqual Maragall Foundation
Hemophilia A
Long-term Study Evaluating Joint Health in People With Haemophilia A Receiving Real-world Prophylactic Treatment With Efanesoctocog Alfa
The rationale for this study is to further understand and describe the long-term prophylactic effectiveness of efanesoctocog alfa in preventing joint bleeds in a real-life setting.
- Trial name
- NCT06940830
- Testing
- Efanesoctocog alfa
- Where
- 31 sites in Croatia, Czechia and 6 more
- Volunteers
- 252 people
- Sponsor
- Swedish Orphan Biovitrum
Parent-Child Relations, Infant Development
The Playful Learning in Infancy Program
In the Playful Learning in Infancy Program, parents receive research-based educational guidance on playful interactions with their infants aged 0-1 year.
- Trial name
- PLIP (NCT06352229)
- Testing
- Playful Learning in Infancy Program, Postnatal care as usual
- Where
- Denmark
- Volunteers
- 2,327 people
- Sponsor
- University of Copenhagen
Cardiovascular Diseases (CVD)
Effectiveness of the "Aktivplan" Digital Intervention for Supporting Regular Heart-Healthy Physical Activity Following Phase II Cardiac Rehabilitation
After a cardiac event like a heart attack or heart surgery, regular heart-healthy exercise is important to reduce the risk of further cardiac events and improve quality of life.
- Trial name
- ACTIVE-CaRe (NCT07878520)
- Testing
- aktivplan
- Where
- Austria
- Volunteers
- 68 people
- Sponsor
- Salzburg Research Forschungsgesellschaft mbH
Obesity
Community Based Obesity Prevention Among Blacks
The purpose of this study is to examine whether pedometer step count recommendations (10,000 steps/day versus an adaptive recommendation) are differentially associated with the primary outcome of adherence to the pedometer-based…
- Trial name
- NCT00939081
- Testing
- Adaptive step recommendation, 10,000 step/day recommendation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Duke University
HIV, HIV Infections
Training Community Members to Deliver HIV Prevention Programs to Urban Youth
This study will examine methods for involving local community members in programs to teach urban youth about how to prevent transmission of HIV.
- Trial name
- NCT00859144
- Testing
- Be Proud! Be Responsible!, Becoming A Responsible Teen (BART), Reducing the Risk
- Where
- United States
- Volunteers
- 901 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Obsessive-Compulsive Disorder
Combining Acceptance and Commitment Therapy With Exposure and Response Prevention to Enhance Treatment Engagement
The aim of the study was to evaluate whether integrating Acceptance and Commitment Therapy (ACT) with Exposure and Response Prevention (ERP) increases the acceptability, tolerability, and adherence with ERP techniques relative to…
- Trial name
- NCT03343106
- Testing
- ACT plus ERP, ERP alone
- Where
- 2 sites in United States
- Volunteers
- 58 people
- Sponsor
- Utah State University
Behavior and Behavior Mechanisms
Families Talking Together Plus: An Approach to Promote Sexual Delay and Strengthen Sexual Risk Avoidance Education
Despite reductions in adolescent sexual behavior over the past decade, premature sexual activity remains prevalent among adolescents and alarming adolescent sexual and reproductive health (SRH) disparities exist.
- Trial name
- FTT+ (NCT04731649)
- Testing
- Families Talking Together Plus (FTT +)
- Where
- United States
- Volunteers
- 1,227 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Hand Hygiene Training, Infection Prevention and Control
Effectiveness of an Edge AI-based Augmented Reality System for Hand Hygiene Training: a Multi-centre, Mixed-methods Cluster Randomised Controlled Trial
This multi-centre, mixed-methods cluster randomised controlled trial (cRCT) aims to evaluate the effectiveness of an edge artificial intelligence (AI)-based augmented reality (AR) training and assessment system for improving hand…
- Conditions
- Hand Hygiene Training, Infection Prevention and Control, Healthcare-Associated Infections (HAIs), Health Education
- Trial name
- HANDHEART (NCT07280026)
- Testing
- Instructional Video + Scanner Feedback, Edge AI-based AR Hand Hygiene Training System
- Where
- 3 sites in China, Hong Kong
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Childhood Obesity Prevention
Early-Life Strategies for Preventing Obesity in Preschool-aged Children
The PKU-SMART is a cluster randomized controlled trial conducted in Jinan, Shandong Province, China. This preventive intervention study aims to develop and evaluate a comprehensive obesity intervention framework for preschool…
- Trial name
- NCT07117149
- Testing
- multicomponent, tiered intervention
- Where
- China
- Volunteers
- 980 people
- Sponsor
- Peking University
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