Clinical trials: Health Prevention
Suicide, Primary Care
Implementing Suicide Prevention Into Primary Care in Nepal
Suicide remains a major contributor to global mortality, with particularly high and persistent rates in low-resourced settings such as South Asia.
- Trial name
- NCT07362056
- Testing
- Suicide Prevention Package (PSuPP)
- Where
- Nepal
- Volunteers
- 147 people
- Sponsor
- Yale University
Pregnancy-Associated Hypertension, Gestational Hypertension
Community Health Worker Support to Lower Blood Pressure After a Pregnancy With High Blood Pressure
High blood pressure during or after pregnancy (such as preeclampsia, gestational hypertension, eclampsia, or Hemolysis, Elevated Liver enzymes, and Low Platelet (HELLP) syndrome) raises a mother's risk of heart disease later in…
- Conditions
- Pregnancy-Associated Hypertension, Gestational Hypertension, Preeclampsia, Eclampsia
- Trial name
- AW2H (NCT07778966)
- Testing
- Alabama Womb to Heart Solution (AW2H) Community Health Worker (CHW) Program, Usual postpartum care with self-measured blood pressure education and home blood pressure monitor
- Where
- United States
- Volunteers
- 174 people
- Sponsor
- University of Alabama at Birmingham
Anxiety, Mental Health Disorder
Preventing Mental Disorders Among Women Internally Displaced by War in Ukraine: The SHAWL Trial
This study is a randomized controlled trial among 120 recently displaced women to determine the effectiveness of a single-session Acceptance and Commitment Therapy (ACT) group therapy on prevention of development of mental health…
- Conditions
- Anxiety, Mental Health Disorder, War-Related Trauma, Acceptance and Commitment Therapy
- Trial name
- SHAWL (NCT06679114)
- Testing
- Acceptance and Commitment Therapy, Attention control
- Where
- Ukraine
- Volunteers
- 120 people
- Sponsor
- Boston Medical Center
COVID-19, SARS-CoV 2
COVID-19: Povidone-Iodine Intranasal Prophylaxis in Front-line Healthcare Personnel and Inpatients
Povidone-iodine (PVP-I) is a broad-spectrum antiseptic with activity against bacteria, fungi, and viruses. It has been previously used in both intranasal preparations against Methicillin Resistant Staphylococcus Aureus (MRSA) as…
- Trial name
- PIIPPI (NCT04364802)
- Testing
- Povidone-Iodine Nasal Spray and Gargle
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Nikita Gupta
PreDiabetes, Prediabetic State
Small Steps for Big Changes - Recipe for Health
The purpose of this study is to evaluate changes in HbA1c levels, diet, weight and waist circumference in Small Steps for Big Changes (SSBC) diabetes prevention program participants two year after program completion compared to…
- Trial name
- RFH (NCT05962983)
- Testing
- Small Steps for Big Changes Program
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- University of British Columbia
Treatment Adherence and Compliance, Anxiety
Global Controlled Trial on Effects of an Online Self-Help Program for of Ambitious Altruists on Their Mental Health, Wellbeing, and Productivity: Comparing Versions With IFS vs. CBT, Buddy- vs. Group-, Standard- vs. Minimum-Guidance Intensity.
This study aims to compare different versions of a 16-week online self-help program in terms of their effect on self-assessed mental health, well-being, and productivity.
- Conditions
- Treatment Adherence and Compliance, Anxiety, Depression, Mental Health Issue
- Trial name
- CT_DoBetter (NCT06442072)
- Testing
- guided online self-help program
- Where
- Netherlands
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Rethink Wellbeing
Prostate Cancer
Prevention of Micro-architectural Bone Decay in Males With Non-metastatic Prostate Cancer Receiving Androgen Deprivation Therapy (ADT)
Less than 20% of men in whom prostate cancer is diagnosed early die from it. Cardiovascular disease is the most common cause of death in men with early prostate cancer.
- Trial name
- NCT01006395
- Testing
- Zoledronic acid
- Where
- Australia
- Volunteers
- 64 people
- Sponsor
- Austin Health
Gingival Health, Metal-Ceramic Restorations
Long-Term Periodontal Tissue Changes Associated With Metal-Ceramic Crowns: An 8-Year Split-Mouth Study
The goal of this clinical trial is to to evaluate the periodontal condition around metal-ceramic crown. The main question to be answered is: whether the metal-ceramic crown is the cause of gum changes? The study offers to involve…
- Trial name
- NCT07500636
- Testing
- Metal-ceramic crown
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Riga Stradins University
HIV, Mental Health
Social Contact-Based Brief Video Interventions To Reduce Stigma and ImproVe Engagement in HIV Prevention and Care and Mental Health Care for Youth Living With and Vulnerable to HIV
HIV stigma, poverty, and racism contribute to high rates of mental health problems and impede treatment for young sexually minoritized men living with and vulnerable to HIV.
- Trial name
- STRIVE (NCT07851077)
- Testing
- Brief Videos for HIV Stigma
- Volunteers
- 3,900 people, healthy volunteers welcome
- Sponsor
- City University of New York, School of Public Health
Hepatitis C, Liver Diseases
Improving Hepatitis C Treatment in Injection Drug Users
The overall goal of the research project is to improve the outcome of medical care for injection drug users (IDUs) with Hepatitis C viral (HCV) infection.
- Conditions
- Hepatitis C, Liver Diseases, Drug Abuse, Alcoholism
- Trial name
- NCT00148031
- Testing
- Pegylated Interferon and Ribavirin, Psychosocial, On-site (MMT Clinic) HCV evaluation and treatment
- Where
- 2 sites in United States
- Volunteers
- 111 people
- Sponsor
- State University of New York - Upstate Medical University
Overweight, Childhood, Obesity Prevention
High Five! - School-based Prevention of Overweight and Obesity Among 6 to 9 Year Olds
The goal of this interventional study is to assess the effectiveness of the school-based "High Five!" program in reducing overweight, obesity and high blood pressure in children aged 7-9 years old.
- Conditions
- Overweight, Childhood, Obesity Prevention, Blood Pressure
- Trial name
- DINO-PL (NCT07357857)
- Testing
- High Five
- Where
- Poland
- Volunteers
- 659 people, healthy volunteers welcome
- Sponsor
- Institute of Mother and Child, Warsaw, Poland
Benzodiazepine Dependence, Benzodiazepine Abuse
Prevention of Benzodiazepine Misuse in Primary Care
Benzodiazepines and benzodiazepine-like hypnotics (z-drugs) are prevalent and addictive narcotics. Guidelines recommend restricted prescription of these drugs for anxiety and insomnia.
- Conditions
- Benzodiazepine Dependence, Benzodiazepine Abuse, Substance Use Disorders
- Trial name
- NCT04533230
- Testing
- Educational intervention with prescription feedback, Information on treatment guidelines
- Where
- Sweden
- Sponsor
- Karolinska Institutet
Cardiovascular Disease
High Cardiovascular Risk Management and Salt Reduction in Rural Villages in China
Cardiovascular disease is the leading cause of death in China. At the village level, strategies for the control of cardiovascular disease are mostly absent.
- Trial name
- NCT01259700
- Testing
- High-risk patient standardized management package, Community based salt reduction program
- Where
- 5 sites in China
- Volunteers
- 120 people
- Sponsor
- The George Institute for Global Health, China
Healthcare Fraud Schemes, Kickback Networks
Healthcare Integrity & Anti-Fraud Enforcement
The PHX-AFK-US Protocol is a coalition-backed regulatory scaffold designed to restore healthcare integrity across U.S. facilities.
- Conditions
- Healthcare Fraud Schemes, Kickback Networks, Supply Chain Vulnerabilities, Governance Failures
- Trial name
- PHX-AFK-US (NCT07217730)
- Testing
- Validator-Governed Reform & Regulatory Escalation Protocol, Coalition-Grade Validator Dashboard Module (CVDM-1), Coalition-Flagged Pharmaceutical Audit Trigger (CFPAT-1)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Truway Health, Inc.
Suicide, Health Care Seeking Behavior
Program to Promote Engagement in Care for the Prevention of Recidivism
In France, the number of emergency visits for suicide attempts is estimated at 220,000 per year. Suicide management aims to reduce suicide risk factors in order to improve the mental health of patients and prevent recurrences.
- Conditions
- Suicide, Health Care Seeking Behavior, Case Management
- Trial name
- PEPS (NCT04366466)
- Testing
- suicide attempt patient using PEPS Program
- Volunteers
- 138 people
- Sponsor
- Januel
Type 2 Diabetes, Men
PowerUp for Health: A Diabetes Prevention Program for Men
The purpose of this two-year proposal is to: 1. develop and 2. complete a pilot test of an adaptation of the evidence-based National Diabetes Prevention Program (NDPP) tailored to engage men with prediabetes in disadvantaged…
- Trial name
- NCT02555631
- Testing
- lifestyle
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Postpartum Depression
In-person vs. Virtual Delivery of a Group-based Prevention of Postpartum Depression
The goal of this clinical trial is to test whether an established preventive intervention (group interpersonal therapy) delivered virtually shows the same benefits for preventing postpartum depression as it does when delivered in…
- Trial name
- NCT05766475
- Testing
- ROSE Program: In Person, ROSE Program: Virtual
- Where
- United States
- Volunteers
- 900 people
- Sponsor
- University of Denver
Non-Small Cell Lung Carcinoma, Compliance Behavior
Patient Navigation for Lung Cancer Screening in an Urban Safety-Net System
The study proposes to evaluate a patient navigation intervention among a sample of 446 individuals referred for CT-based lung cancer screening in an urban safety-net setting.
- Conditions
- Non-Small Cell Lung Carcinoma, Compliance Behavior, Prevention Harmful Effects
- Trial name
- NCT02758054
- Testing
- Patient Navigation
- Where
- United States
- Volunteers
- 447 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Dietary Habits, Accidental Falls
Workshop for Primary Prevention of Falls. CHANGING TO NEVER FALL. CTNF
The purpose of this study is to determine whether a primary prevention workshop is effective decreasing at least 13% the annual incidence of falls in elderly compared to the habitual counseling.
- Conditions
- Dietary Habits, Accidental Falls, Unspecified Fall, Occurrence at Home, Physical Activity
- Trial name
- CTNF (NCT02645006)
- Testing
- 3 session workshop, 1 session workshop
- Where
- Spain
- Volunteers
- 316 people
- Sponsor
- Sociedad Madrileña de Medicina de Familia y Comunitaria
Obsessive-Compulsive Disorder
Child and Adolescent OCD Outcomes From Exposure and Response Prevention Video Teletherapy Treatment
This is a naturalistic, observational study of children and adolescents with obsessive-compulsive disorder who were treated with exposure and response prevention via video teletherapy.
- Trial name
- NCT06466447
- Testing
- Exposure and response prevention therapy
- Where
- United States
- Volunteers
- 2,173 people
- Sponsor
- NOCD
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