Clinical trials: Health Prevention
Hiv, Minority Stress
Developing an Online Mindfulness-based Intervention to Reduce Minority Stress and HIV Risk Among Young Adult MSM - Aim 3
The overall aim of the research study is to develop and test a mindfulness-based program for young adult gay, bisexual, and queer men at risk for HIV (Brown University IRB approved protocol #2004002698).
- Conditions
- Hiv, Minority Stress, Mental Health Wellness 1
- Trial name
- MBQR (NCT05855655)
- Testing
- Mindfulness-Based Queer Resilience (MBQR)
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Brown University
Rheumatic Heart Disease
A Non-Inferiority Trial of Stopping Penicillin in Early Rheumatic Heart Disease: GOAL-Stop
GOAL-Stop is a randomized, controlled, non-inferiority trial designed to evaluate whether discontinuing secondary antibiotic prophylaxis (SAP) is non-inferior to continuing SAP in preventing progression of rheumatic heart disease…
- Trial name
- GOAL-Stop (NCT07146048)
- Testing
- Secondary Prophylaxis
- Where
- Uganda
- Volunteers
- 922 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Alcohol Prevention, Mental Health
Feasibility and Effectiveness of Gamified Digital Intervention to Prevent Alcohol and Mental Health Risks
This study evaluates the impact of a novel smartphone application on alcohol consumption, alcohol-related problems, and psychological well-being.
- Trial name
- NCT07546604
- Testing
- Gamified Social App Supporting Womens' Health & Well-being, Psychoeducational Resource Library Access Only
- Where
- United States
- Volunteers
- 1,752 people, healthy volunteers welcome
- Sponsor
- Loyola Marymount University
Colon Cancer, Lung Cancer
Effectiveness of Electronic Health Record-Based Interventions for Improving Follow-Up in Primary Care
Diagnostic delays in ambulatory care are often due to breakdowns of related care processes. Electronic systems can improve follow-up and reduce delays by detecting missed appointments or incomplete procedures so that patients are…
- Conditions
- Colon Cancer, Lung Cancer, Prostate Cancer
- Trial name
- NCT01346839
- Testing
- Contact Intervention
- Where
- 2 sites in United States
- Volunteers
- 1,256 people
- Sponsor
- Baylor College of Medicine
Ebola Virus Disease, Marburg Virus Disease
Evaluation of Safety, Tolerability and Immune Responses of Ebola-S and Marburg Vaccines in Healthy Adults
Primary Objective: To evaluate the safety and tolerability of cAd3-EBO-S and cAd3 Marburg vaccines when administered Intramuscular (IM) at a dose of 1 x 10^11 particle units (PU) to healthy adults.
- Trial name
- NCT04723602
- Testing
- cAd3-Marburg, cAd3-EBO-S
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Albert B. Sabin Vaccine Institute
Smoking Cessation, Lifestyle, Healthy
Community-Centered eHealth Smoking Cessation Intervention(CCeSCI)
Recent findings regarding why Chinese male smokers are reluctant to quit have offered insight for a possible new solution. Consistent with the Cognitive Dissonance Theory, "smoking rationalization beliefs" are a set of beliefs by…
- Trial name
- NCT05508672
- Testing
- Community-Centered eHealth Smoking Cessation Intervention (CCeSCI), Traditional "smoking is harmful" education
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Duke Kunshan University
Adolescent Behavior, Health Behavior
Effectiveness of the Updated Version of the School-based Program Diario Della Salute (DDS-2)
This study evaluates the short- and long-term effects on psychological wellbeing and health-related behaviours of the updated version of a universal school-based program called Diario della Salute (DDS-2) in Italian students aged…
- Conditions
- Adolescent Behavior, Health Behavior, Mental Health Wellness 1
- Trial name
- DDS-2 (NCT02683811)
- Testing
- Diario della Salute (DDS-2)
- Where
- 5 sites in Italy
- Volunteers
- 3,600 people, healthy volunteers welcome
- Sponsor
- Azienda Sanitaria Locale CN2 Alba-Bra
Type 2 Diabetes Mellitus, Primary Prevention
The Impact of a Diabetes Risk Prediction Model in Primary Care.
Little evidence exists on the impact of diabetes risk scores, e.g. on physicians and patient's behavior, perceived risk of persons, shared-decision making and particularly on patient´s health.
- Trial name
- NCT03234322
- Testing
- external validated risk prediction model
- Where
- Germany
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- German Diabetes Center
Adolescent Obesity
Effectiveness of a Mobile Health Intervention for the Prevention of Overweight and Obesity in Adolescents
The prevention of overweight and obesity in adolescents is a public health priority given the impact of obesity on both short- and long-term health.
- Trial name
- NCT05329753
- Testing
- Mobile health application
- Where
- Spain
- Volunteers
- 305 people, healthy volunteers welcome
- Sponsor
- University of Cadiz
Obesity, Smoking Cessation
Addressing Post Cessation Weight Gain
Some individuals smoke with the perception that smoking helps control body weight. Smokers gain an average of as much as 10 pounds in the months following smoking abstinence, with heavier and more-dependent smokers gaining more…
- Trial name
- NCT02412631
- Testing
- lorcaserin, Varenicline
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Tobacco Use Cessation
Project Impact: A Culturally-Tailored Adherence Intervention for Latino Smokers
The goal of this research study is to collect information from Latino and Hispanic smokers and recent quitters about factors that are important to them when they are trying to quit.
- Trial name
- NCT01811628
- Testing
- Questionnaire, Interview
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Preterm Infants
Protocol-driven Nutrition in Preterm Infants
The project is a national, prospective, multicenter, interventional pilot project focused on protocol-driven nutrition in preterm infants in the Czech republic.
- Trial name
- NCT07364500
- Testing
- Nutrition plan supported by advanced clinical nutrition software
- Where
- 5 sites in Czechia
- Volunteers
- 400 people
- Sponsor
- Institute of Health Information and Statistics of the Czech Republic
Infectious Diseases, Attitude
Omaha System-Based Health Application on Improving Knowledge, Attitude, and Behaviors Regarding Infectious Disease Prevention in the Community
Background: Infectious diseases remain significant public health concerns due to several factors such as climate and environmental changes and natural disasters.
- Conditions
- Infectious Diseases, Attitude, Behavior, Knowledge
- Trial name
- NCT07048301
- Testing
- BUHOS app, Control Group
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Atrial Fibrillation, Arrhythmias, Cardiac
Wearable Cardiac Monitor to Enhance Detection of Arrhythmia Recurrence After Catheter Ablation of Atrial Fibrillation
The WEAR-AF study is a prospective, multicenter clinical trial designed to evaluate the efficacy of wearable technology in the detection, monitoring, and management of atrial fibrillation (AF).
- Conditions
- Atrial Fibrillation, Arrhythmias, Cardiac, Heart Diseases, Cardiovascular Diseases
- Trial name
- WEAR-AF (NCT06564012)
- Volunteers
- 100 people
- Sponsor
- Sunnybrook Health Sciences Centre
HIV, Sexually Transmitted Diseases
Web-Based Middle School HIV Prevention Curricula: Aspiring for Reach and Impact
The purpose of this study is to evaluate the effectiveness of a web-based HIV, sexually transmitted infection (STI), and pregnancy prevention curriculum as a stand alone intervention for 8th grade students in a large urban school…
- Trial name
- NCT01280136
- Testing
- It's Your Game Tech
- Where
- United States
- Volunteers
- 1,700 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Adolescent Substance Use
Guiding Good Choices for Health
This study evaluates the feasibility and effectiveness of implementing Guiding Good Choices (GGC), an anticipatory guidance curriculum for parents of early adolescents, in three large, integrated healthcare systems.
- Trial name
- GGC4H (NCT04040153)
- Testing
- Guiding Good Choices
- Where
- 3 sites in United States
- Volunteers
- 3,636 people, healthy volunteers welcome
- Sponsor
- University of Washington
Smoking Cessation
Enhancing Relapse Prevention for Smoking Cessation With Repetitive Transcranial Magnetic Stimulation
Tobacco use is one of the most significant cancer control and public health challenges in the US today. Half of all smokers in the US will attempt to quit tobacco each year, but fully 95% of those who attempt to quit will reverse…
- Trial name
- rTMS (NCT02822703)
- Testing
- rTMS Active 20Hz
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- The City College of New York
Cardiovascular Diseases, Heart Diseases
Evaluating the Effectiveness of a Family Heart Health Educational Program (The FIT-Heart Study)
The primary objective of the FIT Heart Study was to test the effectiveness of a hospital-based standardized screening and educational intervention targeted to family members of patients hospitalized with CVD, to increase…
- Trial name
- FIT-Heart (NCT00728637)
- Testing
- Family Passport to Heart Health Program, General Educational Materials
- Where
- United States
- Volunteers
- 501 people, healthy volunteers welcome
- Sponsor
- Columbia University
Adolescent Behavior, Lifestyle Modification
A Family-centred Approach Enhancing Cardiovascular Health in Ugandan Adolescents and Their Families
The FaCe-D Study, with funding from the Canadian Institute for Health Research (CIHR) through Global Alliance for Chronic Diseases (GACD) aims to adapt and implement an evidence-based family centred approach (FCA) to prevent…
- Conditions
- Adolescent Behavior, Lifestyle Modification, Cardiovascular Disease Other
- Trial name
- FaCe-D (NCT07265453)
- Testing
- The immediate (treatment) arm, will receive the FaCe-D intervention comprising of 'HOME VISITS, DIET, PHYSICAL ACTIVITY AND HEALTH MESSAGING, Control Arm - standard of care
- Where
- 2 sites in Uganda
- Volunteers
- 1,280 people, healthy volunteers welcome
- Sponsor
- MRC/UVRI and LSHTM Uganda Research Unit
Smoking, Low Physical Activity Level
Perfect Fit: Evaluation of a Virtual Coach for Smoking Cessation and Physical Activity
The leading cause of disease burden across the globe is cardiovascular disease (CVD). Important modifiable behavioral CVD risk factors include, amongst others, smoking and low physical activity (PA).
- Trial name
- NCT06095999
- Testing
- Perfect Fit intervention: virtual coaching intervention to quit smoking and increase physical activity
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
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