Clinical trials: Health Prevention
Gestational Diabetes, Other "Heavy-For-Dates" Infants
Pregnancy Outcomes and Maternal Insulin Sensitivity
The PROMIS study will focus on maternal insulin sensitivity thourghout pregnancy and postpartum in a moderate to high risk population (BMI ≥25 kg/m2) in developing adverse pregnancy outcomes.
- Conditions
- Gestational Diabetes, Other "Heavy-For-Dates" Infants, Small for Gestational Age Infant, Diabetes Mellitus, Type 2
- Trial name
- PROMIS (NCT04315545)
- Testing
- meal tolerance test
- Where
- 2 sites in Netherlands
- Volunteers
- 30 people
- Sponsor
- University Medical Center Groningen
Refugee Health
Supporting Refugee Parenting Community and Family Mental Health in Tijuana
The goal of this study is to better understand and support parenting practices and family mental health among migrant parents in Tijuana, Mexico. the main questions it aims to answer are: 1.
- Trial name
- NCT06080139
- Testing
- Refugee parenting education in a participatory community
- Where
- Mexico
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Stanford University
Parent-child Interaction
A Primary Prevention Trial to Strengthen Child Attachment in a Native Community
The purpose of this study is to to conduct a randomized controlled trial comparing an intervention group and a control group to evaluate the feasibility of the Promoting First Relationships method in an American Indian community…
- Trial name
- FPT PFR (NCT02139332)
- Testing
- PFR Group, Resource & Referral Group
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Washington
Healthy Lifestyle
STAR-C Digital Coaching Intervention
Objectives: The overall objective is to evaluate the effectiveness of the STAR-C digital coaching intervention for health-related lifestyle behavioural change.
- Trial name
- STAR-C (NCT05864001)
- Testing
- STAR-C mobile app
- Where
- Sweden
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Umeå University
Urinary Incontinence
Evaluation of a New Bladder Health Mobile Application in Pregnancy
Millions of women experience involuntary loss of urine called urinary incontinence (UI). UI can be slightly bothersome or totally debilitating. Women experience UI twice as often as men.
- Trial name
- BHmApp (NCT04074044)
- Testing
- BHmApp
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Corewell Health East
Anxiety, Attachment Disorder
A Good Start to Life - an Early Cross-sectorial Intervention
The aim of the project is to develop and evaluate an interdisciplinary and cross-sectorial intervention targeting pregnant women with psychosocial vulnerabilities.
- Conditions
- Anxiety, Attachment Disorder, Maternal Sensitivity, Depression
- Trial name
- NCT03190707
- Testing
- Intervention
- Where
- Denmark
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Intersectoral Research Unit for Health Services
Type 2 Diabetes, Osteoporosis
Impact of Screening and Multicomponent Exercise on Fall Rates, Fractures, and Cardiovascular Health in Diabetes
The DIACTIVE study is a randomized controlled trial with a 5- year follow-up designed to evaluate the impact of comprehensive screening and multicomponent interventions on fall prevention, bone health, nerve function and…
- Conditions
- Type 2 Diabetes, Osteoporosis, Diabetic Neuropathies, Fall Prevention
- Trial name
- DiaACTIVE (NCT06745544)
- Testing
- Rhythm- and Multitask-Based Activity (RYMA) and Activities of Daily Living (ADL)
- Where
- Denmark
- Volunteers
- 490 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Depressive Symptoms, Anxiety
Pilot Feasibility Trial of the Family Strengthening Intervention in Rwanda (FSI-R)
The research will examine the following Specific Aims: Specific Aim 1: To adapt a U.S.-developed family-focused and strengths-based prevention program to the context of HIV/AIDS-affected families in Rwanda (the…
- Conditions
- Depressive Symptoms, Anxiety, Parenting
- Trial name
- NCT01509573
- Testing
- Family Strengthening Intervention in Rwanda (FSI-R)
- Where
- Rwanda
- Volunteers
- 82 people
- Sponsor
- Harvard School of Public Health (HSPH)
E-cigarette Use/Vaping Prevention, Nicotine Dependence Prevention
A Virtual Reality E-cigarette Prevention and Emotion Regulation Intervention for Adolescents
This study will examine E-Invite Only VR, a novel school-based universal e-cigarette prevention intervention that uses virtual reality (VR) to deliver prevention and emotion regulation skills-building content to middle school…
- Conditions
- E-cigarette Use/Vaping Prevention, Nicotine Dependence Prevention, Adolescent Mental Health
- Trial name
- NCT07460622
- Testing
- Virtual Reality E-Cigarette Prevention Program
- Where
- United States
- Volunteers
- 1,251 people, healthy volunteers welcome
- Sponsor
- Yale University
Neck Pain, Exercise Therapy
Prevention of Neck Pain in Adults With a Back School-Based Intervention.
The study consists of a theoretical and practical intervention based on the Back School. This intervention will be carried out over 8 weeks with a frequency of two sessions per week, for a total of 16 sessions of 45 minutes…
- Conditions
- Neck Pain, Exercise Therapy, Health Education, Primary Prevention
- Trial name
- NCT05260645
- Testing
- Back School
- Where
- Spain
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Vigo
Low-Risk Pregnant Women at Full-Term Gestation, Healthy Fetal Population
Advancing Early Bone Health: New Frontiers for Osteoporosis Prevention
All factors that influence the peak bone mass achieved at skeletal maturity are important in determining an individual's risk of developing osteoporosis later in life.
- Conditions
- Low-Risk Pregnant Women at Full-Term Gestation, Healthy Fetal Population, Healthy Neonatal Population
- Trial name
- REMS-BONE (NCT06750523)
- Testing
- Cord blood sampling, urine sampling, Life style questionnaire
- Where
- 2 sites in Italy
- Volunteers
- 200 people
- Sponsor
- University of Parma
Colon Cancer, Obesity
Fiber-rich Foods to Treat Obesity and Prevent Colon Cancer
This study tests whether a high-fiber diet based on legumes, such as dry beans, can lead to sustained reductions in obesity and colon cancer risk in persons at highest risk, namely overweight or obese, post-polypectomy patients.
- Trial name
- NCT04780477
- Testing
- High Fiber Diet Featuring Legumes (HLD), Healthy American Diet
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Emory University
Healthy Population
Italian Digital Primary Cardiovascular Prevention Study
The CV-PREVITAL study is a randomised clinical trial (RCT) controlled versus usual-care designed to compare the effectiveness of a mobile health (mHealth) intervention with that of usual care in reducing specific cardiovascular…
- Trial name
- CV-PREVITAL (NCT05339841)
- Testing
- Mobile health application
- Where
- 32 sites in Italy
- Volunteers
- 27,520 people, healthy volunteers welcome
- Sponsor
- Centro Cardiologico Monzino
HIV
Exploring HIV Entry Blockade as a Pre-exposure Prophylaxis Strategy in Women
Pre-exposure prophylaxis (PrEP) is an HIV prevention strategy in which HIV medicines are used by a person before they are exposed to HIV in order to decrease his or her chance of getting infected.
- Trial name
- MVC-PREP (NCT01749566)
- Testing
- maraviroc
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Emory University
HIV Prevention, Substance Use
Integrating Sexual Pleasure Into Harm Reduction Services for Men Who Have Sex With Men and Transgender Persons Who Engage in Chemsex or Substance Use in Thailand
The study evaluates the integration of a sexual pleasure-based approach into harm reduction services for MSM and transgender persons engaging in chemsex or substance use in Thailand, using the "Pleasuremeter" tool to improve…
- Conditions
- HIV Prevention, Substance Use, Mental Health, Sexually Transmitted Infections (STIs)
- Trial name
- PLEASURE (NCT07509853)
- Testing
- Pleasuremeter-guided qualitative interview, Pleasuremeter-based sexual pleasure discussion integrated with harm reduction services
- Where
- Thailand
- Volunteers
- 300 people
- Sponsor
- Institute of HIV Research and Innovation Foundation, Thailand
Insomnia, Depression
Perinatal Research on Improving Sleep and Mental Health
The goal of this clinical trial is to compare two sleep programs in pregnant people with insomnia. The main questions it aims to answer are: 1.
- Trial name
- PRISM (NCT05596318)
- Testing
- Digital CBT-I, Digital SHE
- Where
- United States
- Volunteers
- 456 people
- Sponsor
- University of California, San Francisco
Substance Abuse, Post-partum Depression
Cradling Our Future Through Family Strengthening Study
The purpose of this study is to determine whether an in-home, paraprofessional-delivered family strengthening curriculum entitled Family Spirit is effective at increasing parental competence, improving maternal outcomes and…
- Conditions
- Substance Abuse, Post-partum Depression, Depression
- Trial name
- NCT00373750
- Testing
- Family Spirit Intervention
- Where
- 5 sites in United States
- Volunteers
- 322 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Dental Caries
Oral Health Assessment of Children in CP Class
Few oral exams are performed on 6-year-olds (key age for carious disease). This project aims to increase the number of oral check-ups for 6-year-olds in fragile areas (REP/REP+ areas).
- Trial name
- NCT04795258
- Where
- France
- Volunteers
- 671 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Sexually Transmitted Diseases
Sexual Behavior Among Medical Students in Mexico
This study aims to identify factors that influence students to undertake or not sexually transmitted diseases screening tests and to have an actual outlook of how Mexican university students live their sexual life.
- Trial name
- NCT04417426
- Testing
- Survey
- Where
- Mexico
- Volunteers
- 519 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
Anthrax
BARDA Securing Anthrax Immunity For the Elderly
This study is designed to assess the safety and ability of BioThrax and AV7909 anthrax vaccines to generate an immune response in adults ≥ 66 years of age in stable health in comparison to adults 18-50 years of age in stable…
- Trial name
- B-SAFE (NCT03518125)
- Testing
- BioThrax, AV7909
- Where
- 4 sites in United States
- Volunteers
- 305 people, healthy volunteers welcome
- Sponsor
- Biomedical Advanced Research and Development Authority
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