Clinical trials: Health Sciences
Alzheimer Disease, Dementia
CONSTELLATIONS Living Lab: Improving the Care Transitions of Older Adults Living with Neurocognitive Disorders
The prevalence of major neurocognitive disorders (MNCDs), particularly Alzheimer's disease, among older adults is increasing. These individuals and their caregivers often face challenges due to inefficient and poorly coordinated…
- Conditions
- Alzheimer Disease, Dementia, Neurocognitive Decline
- Trial name
- NCT06608589
- Testing
- CoMPAS+ MNCDs Program - Quality improvement program targeting the care transitions of patients living with a major neurocognitive disorder and their caregivers
- Where
- Canada
- Volunteers
- 700 people
- Sponsor
- Laval University
Substance Abuse, Substance Use Disorders
Testing Strategies to Improve Substance Misuse Prevention Research Use in State Policy Contexts
If science is to inform effective substance misuse prevention policy and ultimately improve public health, the field needs an effective strategy for directly supporting policymakers' use of research evidence, yet our field lacks…
- Conditions
- Substance Abuse, Substance Use Disorders, Prevention, Legislation
- Trial name
- NCT06856148
- Testing
- Intervention: RPC Group, Active Comparator: Control Group
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Penn State University
Diabetes, Pharmacist-Patient Relations
Refinement and Testing of Recruitment Methodology for Behavioral Medication Adherence Interventions Using Behavioral Science-based Approaches
The overarching goal of the proposed research is to prepare the clinical pharmacist intervention for sustainable implementation and dissemination.
- Conditions
- Diabetes, Pharmacist-Patient Relations, Medication Adherence
- Trial name
- STIC2IT-2 (NCT06569290)
- Testing
- Primer postcard, Control recruitment letter, Behavioral theory-informed recruitment letter (prospect theory)
- Where
- United States
- Volunteers
- 590 people
- Sponsor
- Brigham and Women's Hospital
Type 2 Diabetes Mellitus With Dawn Phenomena
Research on the Complex Scientific Mechanisms Underlying Exercise and Health: Construction and Application of a Mechanistic Model and Public Database（CISS）
Dear Sugar Lovers: Greetings! In order to improve the knowledge of chronic disease prevention and control of sugar users and promote health, the investigators plan to organise participants to participate in the Diabetes Exercise…
- Trial name
- CISS (NCT06936982)
- Testing
- Sports Exercise, control group
- Where
- China
- Volunteers
- 263 people
- Sponsor
- Aiyoudong Children and Youth Sports Health Research Institute
Post Partum Depression
Adaptation and Pilot Testing of Web and Mobile Interface for the VID-KIDS Intervention
COVID-19 has placed unprecedented strains on parents impacted by toxic stress (depression, addiction, intimate partner violence, and poverty) and reluctant to see mental health-service providers in home/clinic due to fears of…
- Trial name
- VID-KIDS (NCT04818047)
- Testing
- VID-KIDS Intervention Program
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of Calgary
Obesity Prevention, Obesity and Overweight
Empowering Healthy Lifestyle Personalised Intervention to Prevent and Control Obesity: The HealthyW8 Project
The goal of the HealthyW8 study (an intervention study) is: To assess the usefulness and effects of a digital-based healthy lifestyle recommender system (HRLS) on the prevention of obesity in the following propulations…
- Conditions
- Obesity Prevention, Obesity and Overweight, Obesity and Obesity-related Medical Conditions, Digital Health
- Trial name
- HealthyW8 (NCT07011368)
- Testing
- Intervention Group
- Where
- 13 sites in Bulgaria, Denmark and 6 more
- Volunteers
- 2,720 people, healthy volunteers welcome
- Sponsor
- Fundació d'investigació Sanitària de les Illes Balears
Ventilator-Associated Pneumonia (VAP), Neonatal, Bronchopulmonary Dysplasia (BPD)
National Surveillance and Prevention of Neonatal VAP
The goal of this observational study is to improve how hospital-acquired lung infections (called ventilator-associated pneumonia, or VAP) are diagnosed, treated and prevented in very low birth weight (VLBW) infants, babies born…
- Conditions
- Ventilator-Associated Pneumonia (VAP), Neonatal, Bronchopulmonary Dysplasia (BPD), Antibiotic-Resistant Organisms (AROs), Health-Care Associated Infection (HAI)
- Trial name
- NCT07109791
- Where
- Canada
- Volunteers
- 1,500 people
- Sponsor
- University of Alberta
Physical Inactivity, Dyslipidemia
Implementation Facilitation of Exercise is Medicine Greenville
A public health priority exists for the U.S. healthcare sector to integrate physical activity (PA) as a part of the patient care model.
- Conditions
- Physical Inactivity, Dyslipidemia, Obesity and Overweight, Hypertension
- Trial name
- NCT07340580
- Testing
- Clinic Implementation Facilitation
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Cardiovascular Health, Breast Cancer
JUdicious Surveillance for Trastuzumab Induced Cardiotoxicity in the First Year
This study focuses on male and female patients being treated for breast cancer that is positive for the HER2 receptor which requires special treatments targeting that receptor.
- Conditions
- Cardiovascular Health, Breast Cancer, Breast Cancer Early Stage Breast Cancer (Stage 1-3), Cardio-oncology
- Trial name
- JUSTIFY (NCT06930521)
- Testing
- Intervention - Low Risk Group OR Intermediate Risk Group
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- Women's College Hospital
Suicide
Implementing A Secure Firearm Storage Program in Illinois Health Centers in Partnership With AllianceChicago and the Illinois Primary Health Care Association (COMMUNITY ASPIRE)
This randomized controlled trial will take place in up to 15 community health centers across the state of Illinois. Researchers will be studying S.A.F.E.
- Trial name
- NCT06886776
- Testing
- Implementation package (training and facilitation)
- Where
- United States
- Volunteers
- 1,086 people
- Sponsor
- Northwestern University
Autism Spectrum Disorder, Implementation Science
Refining and Implementing Technology-Enhanced Family Navigation to Promote Early Access and Engagement With Mental Health Services for Youth With Autism
This project, Refining and Implementing Technology-Enhanced Family Navigation to Promote Early Access and Engagement with Mental Health Services for Youth with Autism (ATTAIN NAV) is focused on adapting and implementing family…
- Conditions
- Autism Spectrum Disorder, Implementation Science, Mental Health, Behavioral Health
- Trial name
- ATTAIN NAV (NCT05344378)
- Testing
- ATTAIN NAV Technology-Enhanced Family Navigation Model
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Simulation of Physical Illness, Nurse's Role
Comparison of Peer-Led Simulation Facilitation Methods on Nursing Students
There are limited studies in the literature on the peer-led facilitator involved in each stage of the simulation in simulation-based experience in nursing education.
- Trial name
- NCT06171815
- Testing
- Scenario-based simulation
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Cancer
Cancer Prevention and Early Detection Among the Homeless Population: The Health Navigator Model
Prevention and early detection are key for the decrease of cancer-related mortality. However, socially deprived population groups don't have the privilege of unburdened access to the healthcare system.
- Trial name
- CANCERLESS (NCT05406687)
- Testing
- Health Navigator Model
- Where
- 18 sites in Austria, Greece and 2 more
- Volunteers
- 654 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Knee Osteoarthritis
The Efficacy of Exercise and Alternative Applications of NMES on Pain and Function in Patients With Knee OA
The aim of the study was to investigate the efficacy of exercise and different size electrodes of neuromuscular electrical stimulation (NMES) applications on pain, range of motion (ROM), muscle strength, function status and…
- Trial name
- NCT03571698
- Testing
- Neuromuscular Electrical Stimulator
- Volunteers
- 60 people
- Sponsor
- Istanbul University
Polycythemia Vera, ET (Essential Thrombocythemia)
MPN PROGRESSion Registry: Observational Study Tracking Symptoms, Treatments, and Disease Progression in People With Myeloproliferative Neoplasms (MPNs)
The MPN PROGRESSion Registry is a multi-year, observational research study designed to improve understanding of myeloproliferative neoplasms (MPNs)-a group of rare, chronic blood cancers that include polycythemia vera (PV)…
- Conditions
- Polycythemia Vera, ET (Essential Thrombocythemia), Polycythemia Vera (PV), Essential Thrombocythemia (ET)
- Trial name
- NCT07362225
- Where
- 2 sites in United States
- Volunteers
- 5,000 people
- Sponsor
- MPN Research Foundation
Substance Use Disorder, Mental Health Disorder
Employing Peer Outreach and Whole Health in Recovery for Homeless-Experienced Veterans
Homelessness is a national crisis in the United States, particularly in the veteran population. Due to multiple chronic conditions, homeless individuals frequently become hospitalized or are treated in emergency departments.
- Conditions
- Substance Use Disorder, Mental Health Disorder, Homelessness
- Trial name
- EMPOWER (NCT07309224)
- Testing
- Employing Peer Outreach and Whole Health in Recovery (EMPOWER)
- Where
- United States
- Volunteers
- 278 people
- Sponsor
- VA Office of Research and Development
Alcohol-Related Disorders, Substance-Related Disorders
Improving Alcohol and Substance Use Care Access, Outcome, Equity During the Reproductive Years
The goal of this clinical trial is to test the effectiveness of evidence-based Screening, Brief Intervention, and Referral to Treatment (SBIRT) among adult patients who screen positive to one or more risky alcohol or substance…
- Conditions
- Alcohol-Related Disorders, Substance-Related Disorders, Mental Health, Reproductive Health
- Trial name
- NCT05910580
- Testing
- Screening, Brief Intervention, and Referral to Treatment (SBIRT)
- Where
- 4 sites in United States
- Volunteers
- 400 people
- Sponsor
- Emory University
Mental Health, Substance Abuse
Reducing Stigma Toward Mental Illness and Substance Use Issues in Primary Health Care in Chile
This research project aims to determine the effectiveness of a comprehensive anti-stigma intervention in reducing stigmatizing attitudes and behaviours among Primary Health Care (PHC) providers toward individuals with mental…
- Conditions
- Mental Health, Substance Abuse, Stigmatization
- Trial name
- NCT05578066
- Testing
- Developing teams of Local Leaders, Analysis of Internal Policies, Procedures and Protocols, Raising Awareness
- Where
- Chile
- Volunteers
- 16 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Colorectal Cancer, Social Determinants of Health
Paired Promotion of Colorectal Cancer and Social Determinants of Health Screening
This work is an implementation science study that examines different aspects of implementing a single intervention. The intervention consists of asking community health centers to implement an outreach strategy to screen patients…
- Trial name
- NCT04585919
- Testing
- Paired Screening Intervention
- Where
- 4 sites in United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Pain, Chronic
An Evaluation of a Public Health Campaign in a High School Setting Targeting Pain Related Knowledge and Beliefs
The beliefs held by students lead to behaviours in response to their pain which can be both helpful or a hindrance to how they manage their pain.
- Trial name
- NCT05636345
- Testing
- pain science education
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Teesside University