Clinical trials: Health Systems, open to volunteers
Friedreich Ataxia
A Study to Learn How BIIB141 (Omaveloxolone) Affects the Health of Participants With Friedrich's Ataxia Who Took it During Pregnancy and/or During Breastfeeding and About the Health of Their Babies
In this study, researchers will learn more about the safety of BIIB141, also known as omaveloxolone or SKYCLARYS. This is a drug available for doctors to prescribe for people with Friedrich's Ataxia, also known as FA.
- Trial name
- NCT06628687
- Testing
- Omaveloxolone
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Biogen
Brain Cancer
Living Well With Brain Cancer: A Group-Based Intervention to Promote Whole-Person Well-Being
The goal of this clinical trial is to learn if the newly designed group self-management program is feasible to conduct and improves mental and behavioral health outcomes compared to a control group in people diagnosed with brain…
- Trial name
- LWBC (NCT07628647)
- Testing
- Group Self-Management Sessions, Educational Materials Only
- Where
- 2 sites in United States
- Volunteers
- 64 people
- Sponsor
- University of Colorado, Denver
Adult Day Programs, Continuing Care
EXploring Patterns of Use and Effects of Adult Day Programs to Improve Trajectories of Continuing CarE
This study seeks to understand the impact of Canada's adult day program on attendees and non-attendees, especially those with dementia and other co-morbidities.
- Conditions
- Adult Day Programs, Continuing Care, Old Age; Dementia, Family/friend Caregivers
- Trial name
- EXPEDITE (NCT06440447)
- Testing
- Adult day program use, Other community care (non-attendees)
- Volunteers
- 500,000 people
- Sponsor
- York University
Lymphoma, Sarcoma
WATCH (Wearable Artificial inTelligence for Cardiac Function and Health Monitoring)
The purpose of this study is to find a cost effective cardiovascular (CV) surveillance of cancer survivors over long periods of time to prevent the risk of progression of heart failure (HF) and related morbidity and mortality.
- Trial name
- NCT07058064
- Testing
- Electrocardiogram, Echocardiogram, LVEF echocardiogram
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Mayo Clinic
Type 2 Diabetes
SALUD-M: Acceptance Based Coping Skills for Hispanic/Latinx Military Patients With Type 2 Diabetes
People of Hispanic or Latino/a/x ("H/L") ethnicity, including US military servicemembers, Veterans, and their families, experience a higher prevalence of type 2 diabetes and more challenges managing diabetes than non-Hispanic…
- Trial name
- SALUD-M (NCT07674628)
- Testing
- Acceptance Based Coping (ABaCo) Skills Program
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Baylor College of Medicine
Suicide, Mental Health Disorder
A Just-in-time Adaptive Intervention for Suicide Safety Planning in Adolescents
Despite efforts to prevent suicide, US rates are climbing, and suicide is the second leading cause of death amongst youth. Digital tools, especially personal smartphones, are promising avenues to address these issues and can be…
- Conditions
- Suicide, Mental Health Disorder, Anhedonia
- Trial name
- ViraSafeRCT (NCT07348666)
- Testing
- ViraSafe: Treatment pushes, BRITE
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- Ksana Health
Community-Based Participatory Research
Evaluating Family & Community-Based Interventions to Improve Treatment Adherence in Metabolic Health Among Negev Bedouins (EFIT-BED)
Background: The Bedouin community in the Negev faces high rates of type 2 diabetes, low treatment adherence, and increased disease complications.
- Trial name
- EFIT-BED (NCT06575465)
- Testing
- Healthy lifestyle nutrition, culture and physical activity workshops, Usual care
- Where
- Israel
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Ariel University
Eating Disorders
A Study to Evaluate Primary Care Treatment for Adolescent Eating Disorders
The purpose of this study is to test the feasibility of a RCT of a new treatment for children and adolescents with eating disorders characterized by dietary restriction and/or weight loss or failure to gain expected weight.
- Trial name
- NCT05814653
- Testing
- Family Based Treatment-Primary Care, Family-Based Treatment
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Mayo Clinic
Cystic Fibrosis (CF), Cardiovascular Disease Risk Factors
Remote Exercise to Improve Physical Activity Levels and Markers of Heart Health in Cystic Fibrosis (RHH-CF)
With advances in genetic therapies, many people with Cystic Fibrosis (CF) are living longer. With the improvement in life expectancy has emerged an increased risk of cardiovascular disease (CVD).
- Trial name
- RHH-CF (NCT07027553)
- Testing
- Mobile health exercise programme, Lifestyle maintenance
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Bath
Mental Disorder, Mental Stress
Virtual Agents-based Digital Interventions to Improve Health
KANOPEE is a free smartphone application providing screening, follow-up tools and autonomous digital interventions to lower psycho-social stress and its repercussions on sleep and behaviors in the general population.
- Conditions
- Mental Disorder, Mental Stress, Insomnia, Depression
- Trial name
- KANOPEE (NCT05074901)
- Testing
- digital behavioral intervention
- Where
- France
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- University of Bordeaux
Otitis Media With Effusion, Acute Otitis Media
Evaluation of Outcomes Following In-office Tympanostomy Using the Tula® System: a Prospective, Multi-center Registry
This prospective, single-arm, multicenter registry is being conducted to collect real world post-market data from patients aged from 6 months to 17 years of age who are undergoing an in-office ear tube placement procedure…
- Conditions
- Otitis Media With Effusion, Acute Otitis Media, Otitis Media
- Trial name
- NCT05915078
- Testing
- Iontophoresis and tube placement
- Where
- 6 sites in United States
- Volunteers
- 200 people
- Sponsor
- Smith & Nephew, Inc.
Ischemic Stroke, Transient Ischemic Attack (TIA)
Secondary Prevention of Ischemic Stroke and Transient Ischemic Attack With an Intelligent Management System
The purpose of this study is to develop a digital health-based intelligent management system for the secondary prevention of ischemic stroke and to evaluate its effectiveness through a multicenter randomized controlled trial…
- Trial name
- SPIRIT (NCT06783049)
- Testing
- Cerebrovascular Disease Secondary Prevention Smart Management System
- Where
- 3 sites in China
- Volunteers
- 4,490 people
- Sponsor
- Beijing Tiantan Hospital
Gastric Atrophy, Gastric Intestinal Metaplasia
A Study Collecting Health Information to Understand and Prevent Gastric Cancer
The purpose of this study is to create a registry of participants with precursor lesions for gastric cancer, including gastric atrophy, intestinal metaplasia, and dysplasia.
- Conditions
- Gastric Atrophy, Gastric Intestinal Metaplasia, Dysplasia, Gastric Adenocarcinoma
- Trial name
- NCT06370143
- Testing
- Questionnaire
- Where
- 7 sites in United States
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Primary Immunodeficiency
Quality of Life Among Children With Inborn Error of Immunity
In this study, we aim to assess the QOL of pediatric IEI patients compared with healthy controls and to determine different factors affecting QOL in these patients.
- Trial name
- NCT07262047
- Testing
- Quality of Life Assessment
- Volunteers
- 50 people
- Sponsor
- Sohag University
Sleep Health, Binge Eating
Sleep Optimization to Aid in Recovery Digital Program
The purpose of this pilot study is to evaluate the usability and feasibility of SOAR (Sleep Optimization to Aid Recovery), a brief and self-guided digital program designed to share evidence-based sleep hygiene information with…
- Conditions
- Sleep Health, Binge Eating, Disordered Eating, Sleep Disturbances
- Trial name
- SOARPilot (NCT07518368)
- Testing
- SOAR
- Volunteers
- 154 people
- Sponsor
- University of Nevada, Las Vegas
Life Style
Effect of Physical Activity Pattern on Cardiometabolic Health
The goal of this study is to understand the interaction between the circadian system and physical activity. Participants will: complete 2 inpatient stays perform moderate exercise be provided with identical meals have frequent…
- Trial name
- PACE (NCT05838508)
- Testing
- Exercise intervention
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Cancer, Breast, Cancer, Uterus
With Love, Grandma ("Con Cariño, Abuelita") Pilot Study
The purpose of this study is to assess the feasibility, acceptability, and preliminary effects of a digital (web and mobile-phone-based) program to improve lifestyle behaviors (physical activity, dietary intake) among Hispanic…
- Conditions
- Cancer, Breast, Cancer, Uterus, Cancer, Ovary, Obesity
- Trial name
- NCT05721976
- Testing
- With Love, Grandma ("Con Cariño, Abuelita")
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Miami Sylvester Comprehensive Cancer Center
School Attendance, School Climate
The University of Oregon ACCESS Project
The goal of this clinical trial is to learn if two behavioral interventions work to reduce office disciplinary referrals, improve attendance, and reduce depression and anxiety in 7th grade students.
- Conditions
- School Attendance, School Climate, School Engagement, School Exclusion
- Trial name
- NCT07264621
- Testing
- Inclusive Skill-building Learning Approach (ISLA), Family Check-Up Online (FCU-O), FCU-Online with telehealth coaching
- Where
- 13 sites in United States
- Volunteers
- 1,440 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Healthy, Neurodegenerative Disease
Brain Health Registry: An Online Registry to Identify and Assess Subjects for Brain Research
The overall goal of this project is to identify, assess and longitudinally monitor subjects who are interested in participating in brain research.
- Trial name
- BHR (NCT02402426)
- Where
- United States
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Diabetes, Heart Diseases
Personalized Responses to Dietary Composition Trial 3
The PREDICT 3 study will build on previous research in over 2,000 individuals to further refine machine learning models that predict individual responses to foods, with the aim of advancing precision nutrition science and…
- Conditions
- Diabetes, Heart Diseases, Diet Habit, Diet Modification
- Trial name
- NCT04735835
- Testing
- Dietary Intervention
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 250,000 people, healthy volunteers welcome
- Sponsor
- Zoe Global Limited
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