Clinical trials: Health Volunteer
Healthy, Non-smokers
A Pilot Study to Test Activity of Antimalarial Drugs Against an Induced Malaria Infection in Healthy Volunteers
This is a pilot study of a protocol for inducing a falciparum malaria infection in healthy volunteers in order to test the activity of novel agents being developed as drugs for the treatment of uncomplicated malaria.
- Trial name
- NCT01055002
- Testing
- Blood stage parasite (BSP) inoculum
- Where
- Australia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Medicines for Malaria Venture
Healthy
A Phase I Study of IDP-73152 Mesylate in Health Male Volunteer
A dose block-randomized, double-blinded, placebo-controlled, single dose, dose-escalation clinical phase I study to evaluate the safety, pharmacokinetics and food effect of IDP-73152 mesylate after oral administration in healthy…
- Trial name
- PDF inhibitor (NCT01904318)
- Testing
- IDP-73152 mesylate 40 mg, IDP-73152 mesylate 80 mg, IDP-73152 mesylate 160 mg
- Where
- South Korea
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- IlDong Pharmaceutical Co Ltd
Health Volunteer
A Comparative Pharmacokinetic Study of Single-Dose Administration of HR091506 Tablets From Different Batches in Healthy Subjects
To evaluate the pharmacokinetic characteristics of HR091506 tablets in different batches in healthy subjects after single administration.
- Trial name
- NCT07076459
- Testing
- HR091506 tablet
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Healthy Volunteers
Gut Microbiome and Metabolic Health Study
The goal of this clinical trial is to assess whether TRPTI (oleoylethanolamide) can reduce plasma imidazole propionate levels and improve insulin sensitivity and metabolic health in healthy adults aged 18 years and above with BMI…
- Trial name
- IMPTRP (NCT07457723)
- Testing
- TRPTI 300mg
- Where
- Australia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- RDC Clinical Pty Ltd
Transmission, Patient-Professional
Different Modalities in Reducing Airborne Particulate Concentrations During AGP for Health Volunteers
Several clinical procedures have been described as aerosol generating procedure (AGP), including nebulization, high-flow nasal cannula oxygen therapy, noninvasive ventilation, and bronchial hygiene treatment, etc.
- Trial name
- NCT04681599
- Testing
- Filter, Scavenger face tent
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Healthy Subjects
Clinical Trial In Healthy Volunteers And Health Elderly Volunteers To Evaluate The Safety, Tolerability And Blood Concentration After Single And Multiple Escalating Oral Doses Of PF-06751979.
This study will test the safety, tolerability and blood concentrations of single and multiple oral doses of PF-06751979 in health subjects and healthy elderly subjects.
- Trial name
- NCT02793232
- Testing
- PF-06751979 single dose, PF-06751979 multiple ascending dose, PF-06751979 multiple dose
- Where
- Belgium
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Pfizer
HIV, AIDS
TMC114-TiDP3-C181: Study to Assess the Pharmacokinetics of Darunavir (DRV) With Different Doses of Ritonavir in Healthy Volunteers.
The objectives are to determine the effect of different ritonavir doses on darunavir (DRV) oral exposure following once-daily oral dosing of DRV/rtv for 7 days, in order to establish an optimal ritonavir boosting dose for DRV and…
- Trial name
- NCT00744887
- Testing
- Darunavir
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Tibotec Pharmaceuticals, Ireland
Gut Microbiome, Gut Health
Understanding the Efficacy of Dietary Supplement on Fungal Mycobiota in Healthy Volunteers: A Pilot Study
The purpose of this study is to explore how the dietary supplement L-Phenylalanine affects the production of the metabolite phenylpropionic acid (PPA) and changes fungal populations of the gut microbiome.
- Conditions
- Gut Microbiome, Gut Health, Dietary Supplement, L-Phenylalanine
- Trial name
- NCT06433310
- Testing
- L-Phenylalanine 500 mg Veg Capsule product
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Covid19, Severe Acute Respiratory Syndrome
Safety and Tolerability of COVID-19 Vaccine (ABNCoV2)
This phase 1 trial aims to assess the safety and tolerability of two doses of ABNCoV2, formulated with and without the adjuvant MF59, in healthy adult volunteers and to identify the dosage and formulation that optimizes the…
- Conditions
- Covid19, Severe Acute Respiratory Syndrome, SARS-CoV-2 Infection
- Trial name
- COUGH-1 (NCT04839146)
- Testing
- ABNCoV2 Vaccine
- Where
- Netherlands
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Health, Subjective
A Drug-Drug Interaction Study of CTL0901 and CTL0902 Compared to Coadministration in Healthy Adult Volunteers
This is a two-arm, open-label, single-sequence, multiple-dose, cross-over phase 1 study to evaluate the interaction between two investigational drugs by comparing and analyzing the pharmacokinetic interaction and safety of…
- Trial name
- NCT05009368
- Testing
- Drug: Treatment A, Drug: Treatment B, Drug: Treatment C
- Where
- South Korea
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Celltrion
Smoking Cessation, Nicotine Replacements Therapy
A Study of Nicotine Orodispersible Tablet on Craving Relief of Male and Female Smoker Volunteers
The objective of the study is to evaluate the relief of momentary urge to smoke at pre-specified early post-dose time points after administration of Nic ODT compared to Placebo ODT.
- Trial name
- Zippy PD (NCT07893158)
- Testing
- Nicotine Mint Oro Dispersible Tablet (Nic ODT)
- Where
- Canada
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- McNeil AB
Gardasil Vaccine, Stem Cell Transplant
Gardasil Vaccination in Post Stem Cell Transplant Patients
Background: Gardasil , a recently approved vaccine for the sexually transmitted human papillomavirus (HPV), provides immunity to four types of HPV that are associated with genital warts and cervical, vaginal, and vulvar precancer…
- Conditions
- Gardasil Vaccine, Stem Cell Transplant, Immunogenicity
- Trial name
- NCT01092195
- Testing
- Gardasil
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Anemia
Pharmacokinetics Study of CKD-11101 and NESP After IV Administration in Health Male Volunteers
The purpose of this study is to investigate the pharmacokinetics of CKD-11101 and NESP after IV administration in health male volunteers
- Trial name
- NCT01684605
- Testing
- NESP 60μg, CKD-11101 60μg
- Where
- South Korea
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Health Volunteer
Effect of HRS-8427 for Injection on the Pharmacokinetics of Furosemide and Metformin in Healthy Subjects。
The pharmacokinetics of HRS-8427 for injection on the transporter OAT1 substrate furosemide and the MATE1/METE2-K substrate metformin were evaluated in healthy subjects.
- Trial name
- NCT07073157
- Testing
- HRS-8427 injection plus furosemide, HRS-8427 injection plus metformin
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Alzheimer Disease
Intergenerational Reminiscence and Digital Storytelling
The goal of this clinical trial is to develop and test how reminiscence offered by trained young adult volunteers using a digital storytelling (DST) platform may help older persons with Alzheimer's disease and related dementias…
- Trial name
- NCT05984732
- Testing
- Reminiscence with digital storytelling, Social wellness with scrapbook or journal
- Where
- United States
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Female Community Health Volunteers
Effectiveness of Female Community Health Volunteers Training on Hypertension Knowledge and Blood Pressure Measurement Skills in Nepal
The investigators aimed to investigate the effectiveness of training FCHVs in hypertension knowledge and blood pressure measuring skills and explore their perceptions of challenges and opportunities to deliver hypertension…
- Trial name
- NCT06529289
- Testing
- Training
- Where
- Nepal
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Kathmandu University School of Medical Sciences
Adult Healthy Volunteers
O-LIVE: Impact of a Portuguese Olive Oil in Health Biomarkers
This research project, approved and funded, is part of a larger project, entitled "Healthy Soil for Food", which completes several work packages, one of which is a clinical research submitted to Ethics Committee entitled "O-LIVE…
- Trial name
- O-LIVE (NCT05852275)
- Testing
- Olive-oil
- Where
- Portugal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Católica Portuguesa
Healthy
Pedal Rate Influence on Oxygen Consumption in Eccentric
Nowadays, ECC exercise can be realized using various modalities that target small or large muscle masses in a segmentary or dynamic way.
- Trial name
- PRIOx (NCT02594657)
- Testing
- pedal rate on 50 RPM, pedal rate on 80 RPM
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Mental Health Impairment, Peer Group
Paths to Everyday Life (PEER) - a Community-based Peer Support Intervention
The aim of this randomized, two-arm, investigator initiated, multi municipal, parallel-group superiority trial is to compare the effect on self-reported personal recovery of the following interventions: (1) 10-week group-based…
- Conditions
- Mental Health Impairment, Peer Group, Mental Health Disorder, Problems Psychosocial
- Trial name
- PEER (NCT04639167)
- Testing
- Paths to everyday life (PEER)
- Where
- Denmark
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- Amager Hospital
Psychological Stress, Mental Fatigue
Psychophysiological Effects of Green Exercise in Outdoor Green vs. Indoor Control
Core Purpose: Researchers want to learn if walking in an outdoor green environment helps people recover from mental tiredness and stress better than walking indoors.
- Conditions
- Psychological Stress, Mental Fatigue, Cognitive Dysfunction, Emotional Well-being
- Trial name
- GREEN-OI (NCT07379164)
- Testing
- Outdoor Green Group, Indoor Control Group
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lincoln University College