Clinical trials: Health Volunteer
Healthy Volunteer
Pharmacokinetics, Immunogenicity, Safety and Tolerability of MEDI3506 in Health Chinese Participants
This study is to evaluate the pharmacokinetics, immunogenicity, safety and tolerability of investigational drug MEDI3506 with single dose in Healthy Chinese participants.
- Trial name
- NCT05070312
- Testing
- MEDI3506
- Where
- China
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Safety, Tolerability
A First-in-Human SAD and MAD Study in HV to Evaluate Oral YR011 Tablet
This is a Phase I clinical trial (protocol number: YR-011-B07) sponsored by Hangzhou Yirui Pharmaceutical Technology Co., Ltd., focusing on the novel oral small-molecule drug YR011 (active ingredient: PA032, a Kv1.3 channel…
- Conditions
- Safety, Tolerability, Pharmacokinetic
- Trial name
- NCT07878481
- Testing
- Kv1.3 potassium channel blocker (PA032, investigational oral small-molecule drug)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Hangzhou Yirui Pharmaceutical Technology Co., Ltd
Anemia
Pharmacokinetics Study of CKD-11101 and NESP After SC Administration in Health Male Volunteers
The purpose of this study is to investigate the pharmacokinetics of CKD-11101 and NESP after SC administration in health male volunteers
- Trial name
- NCT01685671
- Testing
- NESP 60μg, CKD-11101 60μg
- Where
- South Korea
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Renal Anemia
Pharmacokinetics Comparison Study of JT1801 and NESP® After Single Dose Administration in Chinese Health Male Volunteers
The purpose of this study is to compare the similarity of major pharmacokinetic parameters after a single intravenous administration of JT1801 and NESP® in chinese healthy male volunteers.
- Trial name
- NCT05864261
- Testing
- JT1801 60ug, NESP 60ug
- Where
- China
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Yi Fang
Healthy Participants With Lower-than-average Mental Well-being
Investigating the Interaction of Psilocybin and Context of Its Administration in Healthy Volunteers
One hundred twenty healthy participants, ages 21 to 70, who experience moderate-to-lower-than-average mental well-being will be evenly randomized into four different study arms, using a 2x2 factorial design.
- Trial name
- SnS (NCT06626139)
- Testing
- Psilocybin, Context 1, Context 2
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Robin Carhart-Harris, PhD, MA
Healthy Human Volunteers, Youth Resilience
"One All" to Get it RYT (Resilient Young Tribal Adults)
:The study is designed to introduce a curriculum "One All", organised around the sport, Ultimate Frisbee, as a way to improve mental health resilience.
- Trial name
- NCT06474260
- Testing
- "One All" Intervention
- Where
- 2 sites in India
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Polycystic Ovary Syndrome, Normal Volunteers
Proteomics & Glyco-Proteomic Analysis of Follicular Fluid
To the best of the investigators knowledge, exhaustive characterization of the low and high abundant proteins and glyco-proteins of the Follicular Fluid (FF) has not yet been achieved.
- Trial name
- NCT01487486
- Testing
- IVF Antagonist Protocol
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Cincinnati
Healthy Volunteers
Evaluation of Assessments of Motor Performance, Physical Impairments and Functional Abilities
This study will evaluate new assessment tools and equipment and new ways of using existing tools and equipment in the NIH Clinical Center s Rehabilitation Medicine Department in order to maximize patients function.
- Trial name
- NCT00747955
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Healthy Volunteers
Tolerability of a Modified Health-Dx
Single Blind, Randomized Control Study is designed to evaluate the tolerability of the Celero Systems' modified Health-Dx™ (mHDx) capsule.
- Trial name
- NCT06240650
- Testing
- modified Health- Dx™ (mHDx) study capsule, modified Health- Dx™ (mHDx) control capsule
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Celero Systems, Inc.
Health Volunteer Validation Study
Vital Signs Validation Study of the μ-Cor System (ViVUS Validation)
This study has the following objective: To validate the capability of the μ-Cor System to monitor ECG, Heart Rate (HR), Respiration Rate (RR), Posture and Activity in healthy human subjects.
- Trial name
- ViVUS (NCT02975050)
- Testing
- Location
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Zoll Medical Corporation
Turner Syndrome, Ovarian Failure, Premature
Dry Eye in Women With Turner Syndrome and Women With Premature Ovarian Failure
Premature ovarian failure (POF) is known to be associated with an increased risk of ocular surface disease (dry eye), likely due to the reduction of both estrogens and androgens seen in this condition.
- Conditions
- Turner Syndrome, Ovarian Failure, Premature, Sex Chromosome Aberrations, Menopause
- Trial name
- NCT00471731
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
IBD, Crohn Disease
Impact Of The Gut Microbiota On Host Cells Energy Metabolism in Health And In Inflammatory Bowel Disease
Inflammatory Bowel Disease (IBD) often leads to poor disease control and reduced quality of life. Changes in the gut microbiota may disrupt the energy metabolism of immune cells, contributing to IBD.
- Conditions
- IBD, Crohn Disease, Ulcerative Colitis (UC)
- Trial name
- ENERGISED (NCT07300553)
- Testing
- Vancomycin /Amphotericin B (Fungizone®) /Gentamicine 80 mg, Inulin/Inulin C13
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diabetes Mellitus, Type 2, Liver Diseases
Validate Smart Breath Analyzer as Screening Tool for Diabetic, Hepatic, Renal, Lung, and Other Metabolic Disorders
This is a prospective, multicentric, non-treatment study to build and validate a portable, non-invasive smart breath analyzer that can screen underlying health issues using exhaled breath.
- Conditions
- Diabetes Mellitus, Type 2, Liver Diseases, Kidney Diseases, Lung Diseases
- Trial name
- RESPYR-SBA (NCT07646015)
- Where
- India
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Respyr
Healthy, Stress-related Problem
The Effect of Probiotic Supplementation on Mental Health in Healthy Volunteers
Probiotics are "live microorganisms which when administered in adequate amounts confer a health benefit on the host". Accumulating evidence indicates their effect in mental health restoration.
- Conditions
- Healthy, Stress-related Problem, Depression, Anxiety
- Trial name
- ProBeMent (NCT06391216)
- Testing
- Lactobacillus helveticus R0052 and Bifidobacterium longum R0175
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University of Lodz
Type2 Diabetes Mellitus
Continuous Multiple Dose PB-119 Injection in Health Volunteers
This is an open label, multiple dose study, pharmacokinetic and pharmacodynamics studies will be performed at the same time with tolerability study.
- Trial name
- NCT03062774
- Testing
- PB-119 injection
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- PegBio Co., Ltd.
Smoking Cessation, Pharmacokinetics
A Clinical Trial to Compare Pharmacokinetics of the "CDFF0318" and "Champix Tab. 1mg"
A Phase 1 Clinical Trial to Compare and Evaluate Safety and Pharmacokinetic Characteristics after Administration of the "CDFF0318" and "Champix Tab. 1mg (Varenicline tartrate)" in Healthy Male Volunteers
- Trial name
- NCT04631874
- Testing
- CDFF0318, Champix
- Where
- South Korea
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- CTC Bio, Inc.
Pain, Acute, Pain, Chronic
Changes in Affective Pain Processing in Human Volunteers
The experience of pain is more than the conscious perception of nociceptive signals. Emotional and motivational aspects accompany pain, leading to its aversiveness and motivation for avoidance.
- Conditions
- Pain, Acute, Pain, Chronic, Low Back Pain
- Trial name
- NCT04280796
- Testing
- psychophysical tasks, cognitive task
- Where
- Switzerland
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- susanne becker
Depression, Anxiety
Enhancing Purpose and Well-Being Through a Volunteering Experience Connecting Veterans With English Language Learners
The goal of this study is to refine and test a strategy for engaging Veterans with symptoms of depression, anxiety, and/or PTSD (Post Traumatic Stress Disorder) as volunteers to help English language learners (ELLs) improve their…
- Conditions
- Depression, Anxiety, Post Traumatic Stress Disorder
- Trial name
- NCT06324383
- Testing
- Intervention (videoconferencing)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Loneliness, Quality of Life
The Helping Older People Engage Project: Improving Social Well-Being in Later Life
Older adults who feel lonely carry increased risk for reduced quality of life, morbidity, and mortality. Volunteering is a promising intervention for reducing loneliness in later life.
- Trial name
- HOPE (NCT03343483)
- Testing
- Volunteering, Life Review
- Where
- United States
- Volunteers
- 291 people
- Sponsor
- University of Rochester
Electrocardiography (ECG), Photoplethysmography
Synchronised ECG and PPG Data Collection for AI-based QT/QTc Reconstruction (ILECS-ECGPPG)
This observational study will collect synchronized photoplethysmography (PPG) and electrocardiogram (ECG) recordings from approximately 50 healthy adult volunteers.
- Conditions
- Electrocardiography (ECG), Photoplethysmography, Healthy Volunteers
- Trial name
- ILECS-ECGPPG (NCT07684807)
- Testing
- Corsano CardioWatch 287-2, VivaLNK wearable ECG patch
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Corsano Health B.V.