Clinical trials: Health Volunteer
Abuse of Anabolic Steroids
Intranasal Delivery of Testosterone and Its Effect on Doping Markers
Hypothesis: Intranasal administration of exogenous testosterone results in a characteristic profile during anti-doping testing, which is different than the profile seen when testosterone is administered into muscle, on skin or…
- Trial name
- Intranasal (NCT02611154)
- Testing
- Testosterone
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Utah
Inflammatory Bowel Diseases
Phase 1 Study for IPG11406 in Health Volunteer
A phase 1, randomized, double-blind, placebo-controlled, single and multiple dose escalation study to evaluate the safety, tolerability, pharmacokinetics (PK) and food effect of orally administered IPG11406 in healthy adult…
- Trial name
- NCT06255834
- Testing
- IPG11406
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Nanjing Immunophage Biotech Co., Ltd
Gardasil Vaccine, Stem Cell Transplant
Gardasil Vaccination in Post Stem Cell Transplant Patients
Background: Gardasil , a recently approved vaccine for the sexually transmitted human papillomavirus (HPV), provides immunity to four types of HPV that are associated with genital warts and cervical, vaginal, and vulvar precancer…
- Conditions
- Gardasil Vaccine, Stem Cell Transplant, Immunogenicity
- Trial name
- NCT01092195
- Testing
- Gardasil
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Health, Subjective
Clinical Study of ALT-BB4 to Determine Tolerance, Safety and Pharmacokinetics in Healthy Volunteer
A Phase I Study to Evaluate the Tolerance, Safety and Pharmacokinetics of ALT-BB4 in Healthy Volunteers
- Trial name
- NCT05232175
- Testing
- ALT-BB4, 0.9%NaCl
- Where
- South Korea
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Alteogen, Inc.
Smoking Cessation
A Study in Healthy Volunteers to Investigate the Effect of Food on the Bioavailability of Cytisine
This will be an open-label, randomised, 2-period, single-dose crossover study to determine the comparative bioavailability of cytisine following single-dose administration in healthy male and female subjects under fed and fasted…
- Trial name
- NCT03268343
- Testing
- Cytisine
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Achieve Life Sciences
Schistosomiasis, Health Education
Health Education Model Led by Community Health Volunteers.
The goal of this intervention study is to investigate the level of knowledge, attitudes, and behaviors of students on schistosomiasis in Pemba Island.
- Trial name
- NCT06312462
- Testing
- health education
- Where
- Tanzania
- Volunteers
- 978 people, healthy volunteers welcome
- Sponsor
- Pemba Ministry of Health Zanzibar
Healthy
Forearm Immobilization, Metabolic Health, and Muscle Loss
The present study will investigate the impact of altered substrate availability on muscle atrophy, insulin sensitivity and muscle protein synthesis following short-term forearm immobilization
- Trial name
- NCT03866512
- Testing
- Forearm immobilization
- Where
- United Kingdom
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Exeter
HIV Infections, Health Volunteers
A Safety, Pharmacokinetics, and Pharmacodynamics Study of ABX464 in HIV-1 Seronegative and Seropositive Adults
The purpose of the ABX464-005 study is to characterize the systemic and mucosal immunological sequelae associated with exposure to ABX464 and to explore selected immunological endpoints, compartmental pharmacokinetics, and…
- Trial name
- NCT02990325
- Testing
- ABX464 150mg, ABX464 50mg
- Where
- Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Abivax S.A.
Chronic Fatigue Syndrome
Myalgic Encephalomyelitis Chronic Fatigue at the National Institutes of Health
Background: Post-Infectious Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (PI-ME/CFS) refers to long-lasting and disabling fatigue or malaise, inability to recover after exercise, and physical and emotional discomfort that…
- Trial name
- NCT02669212
- Testing
- Cardiopulmonary Exercise Test (CPET)
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Caregiver Burnout
Volunteering Program for Chinese Dementia Caregivers
Although many older Chinese Americans are expected to need intensive care because of cognitive impairment, a large gap exists in development of culturally sensitive interventions to reduce stress among caregivers in Chinese…
- Trial name
- NCT04346745
- Testing
- Peer Mentoring Program
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Columbia University
Grief, Post Traumatic Stress Disorder
Building and Sustaining Interventions for Children: Task-sharing Mental Health Care in Low-resource Settings
The BASIC study will take place in Kanduyi/Bungoma South Sub-County, in western Kenya, and focuses on children orphaned by one or two parents.
- Conditions
- Grief, Post Traumatic Stress Disorder, Depression
- Trial name
- BASIC (NCT03243396)
- Testing
- Trauma-Focused Cognitive Behavioral Therapy
- Where
- Kenya
- Volunteers
- 956 people
- Sponsor
- Duke University
Early Child Development
Testing Means to Scale Early Childhood Development Interventions in Rural Kenya
This study aims to experimentally test the effectiveness and cost-effectiveness of competing models of delivery of an Early Childhood Development (ECD) intervention in rural Kenya to determine how to maximize their reach to…
- Trial name
- NCT03548558
- Testing
- Group sessions, Group+Home sessions, Booster sessions
- Where
- United States
- Volunteers
- 1,152 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Healthy Subjects
Clinical Trial In Healthy Volunteers And Health Elderly Volunteers To Evaluate The Safety, Tolerability And Blood Concentration After Single And Multiple Escalating Oral Doses Of PF-06751979.
This study will test the safety, tolerability and blood concentrations of single and multiple oral doses of PF-06751979 in health subjects and healthy elderly subjects.
- Trial name
- NCT02793232
- Testing
- PF-06751979 single dose, PF-06751979 multiple ascending dose, PF-06751979 multiple dose
- Where
- Belgium
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Pfizer
Heart Failure, Obesity
Fatty Acid Radiotracer Comparison Study in Heart Failure Patients
A single center, open-label baseline controlled imaging study to designed to assess whether Positron Emission Tomography (PET) measurements of myocardial Fatty Acid (FA) metabolism performed with [18F]FluorbetaOx correlates with…
- Conditions
- Heart Failure, Obesity, Type 2 Diabetes Mellitus, Health Normal Volunteer Subjects
- Trial name
- NCT01648296
- Testing
- [18F]FluorbetaOx
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Compliance, Patient
Explorative Clinical Study on the Performance and Acceptance of New Intermittent Catheters in Healthy Volunteers
Performance and acceptance of new intermittent catheters tested in healthy volunteers
- Trial name
- NCT04231149
- Testing
- Test product 2, Test product 3, Comparator
- Where
- Denmark
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Coloplast A/S
Tooth Replacement
Dental Implant Study Comparing Two Types of Metals Used for Dental Implants
The purpose of this research study is to compare the healing differences of two metals (trabecular vs. standard titanium) that are used for dental implants.
- Trial name
- ZMU (NCT01714024)
- Testing
- Zimmer Trabecular Metal Test Cylinder, Zimmer Titanium Test Cylinder
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Health Volunteers, Huntington Disease
A Study to Evaluate Sigma-1 and Dopamine-2 Receptor Occupancy by Pridopidine in the Human Brain of Healthy Volunteers and in Patients With Huntington's Disease
The purpose of this study is to demonstrate engagement of pridopidine with S1R and D2R (optional) in the living human brain. No formal statistical analysis will be conducted
- Trial name
- NCT03019289
- Testing
- pridopidine (90 mg)
- Where
- Germany
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Prilenia
Healthy Volunteers
Impact of Steady State Cobicistat and Darunavir/Cobicistat on the Pharmacokinetics and Pharmacodynamics of Oral Anticoagulants (Rivaroxaban, Apixaban) in Health Volunteers
Background: Rivaroxaban and apixaban are blood thinners. People with HIV may need to take them to treat or prevent blood clots. The anti-HIV drug darunavir (DRV) can increase the amount of these blood thinners in the body.
- Trial name
- NCT03864406
- Testing
- Cobicistat, Darunavir/Cobicistat, Rivaroxaban
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Covid19, Severe Acute Respiratory Syndrome
Safety and Tolerability of COVID-19 Vaccine (ABNCoV2)
This phase 1 trial aims to assess the safety and tolerability of two doses of ABNCoV2, formulated with and without the adjuvant MF59, in healthy adult volunteers and to identify the dosage and formulation that optimizes the…
- Conditions
- Covid19, Severe Acute Respiratory Syndrome, SARS-CoV-2 Infection
- Trial name
- COUGH-1 (NCT04839146)
- Testing
- ABNCoV2 Vaccine
- Where
- Netherlands
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Smoking Cessation
A Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD4041 in Healthy Volunteers
This is a Phase I, first-in-human (FIH), single-center, randomized, double-blind, placebo controlled, single ascending dose, sequential group study in healthy vasectomized male and female subjects of non-childbearing potential…
- Trial name
- NCT04076540
- Testing
- AZD4041
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- AstraZeneca