Clinical trials: Health Volunteers
Healthy Participants, Healthy Adult Subject
Satiety, Microbiome, Appetite Regulation, and Tracking Energy Across Targeted Snacks: Acute Postprandial Study
The goal of this clinical trial is to learn how eating different snack foods affects acute hunger, energy intake and eating behaviour in healthy adults. The study will be conducted remotely over 5 days.
- Conditions
- Healthy Participants, Healthy Adult Subject, Healthy Subjects, Healthy Adult Volunteer
- Trial name
- SMARTEATS-PP (NCT07776418)
- Testing
- High-fibre plant-based snack bar, Control snack bars
- Where
- United Kingdom
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Zoe Global Limited
Chronic Disease, Hypertension
Sí Texas Hope Family Health Center
This study evaluated whether uninsured patients living at or below 200% of the federal poverty level who received enhanced, culturally-relevant, integrated behavioral health services were more likely to improve health outcomes…
- Conditions
- Chronic Disease, Hypertension, Diabetes, Hypercholesterolemia
- Trial name
- NCT03916016
- Testing
- Enhanced Integrated Behavioral Health Care, Usual Care
- Volunteers
- 585 people, healthy volunteers welcome
- Sponsor
- Health Resources in Action, Inc.
Healthy Volunteers
Spire Medical Health Tag Actigraphy and Sleep Validation in Adults
The purpose of this study is to collect data to validate the step- (actigraphy) and sleep-tracking performance of the Medical Health Tag device developed by Spire Health.
- Trial name
- NCT04102709
- Testing
- Health Tag
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Spire, Inc.
Healthy Volunteers
Impact of Steady State Cobicistat and Darunavir/Cobicistat on the Pharmacokinetics and Pharmacodynamics of Oral Anticoagulants (Rivaroxaban, Apixaban) in Health Volunteers
Background: Rivaroxaban and apixaban are blood thinners. People with HIV may need to take them to treat or prevent blood clots. The anti-HIV drug darunavir (DRV) can increase the amount of these blood thinners in the body.
- Trial name
- NCT03864406
- Testing
- Cobicistat, Darunavir/Cobicistat, Rivaroxaban
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Healthy Volunteers
The Role of Gut Microbiome on Cardiovascular Health Benefits of Dietary Lignans (CardioFlax Study).
The aim of this study is to investigate the effects of gut microbial metabolism of flaxseed lignans on cardiovascular health. Enterolactone is the main gut microbial metabolite of lignans.
- Trial name
- NCT04179136
- Testing
- lignan capsules contain 300 mg flaxseed (SDG) extract
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- King's College London
Healthy, Healthy Lifestyle
TirolGESUND: Baseline-controlled Comparison of the Effects of Fasting Dietary Intervention or Smoking Cessation Combined With Exercise in Healthy Female Tyrolean Volunteers Aged 30-60 on Epigenetic and Multi-omic Biomarkers of Health, Ageing, and Disease
The goal of this clinical study is to learn about disease-risk and age-associated changes in DNA methylation patterns associated with disease risk or age in healthy women aged 30-60 in response to health-promoting lifestyle…
- Conditions
- Healthy, Healthy Lifestyle, Smoking Cessation, Intermittent Fasting
- Trial name
- TirolGESUND (NCT05678426)
- Testing
- Smoking cessation, Intermittent fasting, Intermittent fasting with ketogenic supplement
- Where
- Austria
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Universitaet Innsbruck
Smoking Cessation
A Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD4041 in Healthy Volunteers
This is a Phase I, first-in-human (FIH), single-center, randomized, double-blind, placebo controlled, single ascending dose, sequential group study in healthy vasectomized male and female subjects of non-childbearing potential…
- Trial name
- NCT04076540
- Testing
- AZD4041
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy, HIV
Safety and Pharmacokinetics (PK) of a Polyurethane Tenofovir Disoproxil Fumarate (TDF) Vaginal Ring (TDF IVR-002)
This prospective, two-site, two-arm, randomized, single-blind, placebo-controlled trial will examine the safety and pharmacokinetics (PK) of a polyurethane tenofovir disoproxil fumarate (TDF) vaginal ring when used continuously…
- Trial name
- TDF IVR-002 (NCT02762617)
- Testing
- Tenofovir disoproxil fumarate intravaginal ring
- Where
- 2 sites in United States, Kenya
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Marla Keller
Diarrhoea, Pneumonia
HCU: Can VHVs Trained in ICCM Improve Care for Children
This study will assess how the current VHV (VHV=CHW, community health worker) scope can be expanded to include iCCM and if such group interventions can provide improved access to treatment for children.
- Conditions
- Diarrhoea, Pneumonia, Malaria
- Trial name
- HCU:VHV/ICCM (NCT02072629)
- Testing
- Training of VHVs in iCCM
- Volunteers
- 4,071 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Healthy
A Drug Interaction Study of Montelukast and Levocetirizine
The purpose of this study is to evaluate the drug-drug interaction between montelukast sodium and levocetirizine dihydrochloride in healthy male volunteers.
- Trial name
- MOLZ (NCT01491503)
- Testing
- Levocetirizine, montelukast sodium, Montelukast & levocetirizine
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Hanmi Pharmaceutical Company Limited
Systemic Lupus Erythematosus
A Phase Ia Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Subcutaneously Administered CUG252 in Normal Healthy Volunteers
The intent of this study is to evaluate the safety and tolerability of single escalating subcutaneous doses of CUG252 in healthy adult subjects.
- Trial name
- NCT05328557
- Testing
- CUG252
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cugene Inc.
Healthy Volunteer EGEA4 Cohort
EGEA4 THE 30 YEAR FOLLOW UP OF THE EGEA STUDY
Cardiovascular (CV) diseases affect 523 million people worldwide, and are the leading cause of death, accounting for over 18 million deaths (around 30% of all deaths) every year.
- Trial name
- NCT06334705
- Testing
- blood test, food collection, hair collection, calcium scan, etc.
- Where
- 5 sites in France
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Smoking
Evaluation of Peer Telephone Cessation Counseling for Smokers
The purpose of this study is to evaluate the peer telephone cessation counseling that has been and continues to be implemented at the Ann Arbor VA as part of the Tobacco Tactics intervention.
- Trial name
- NCT01359371
- Testing
- Peer telephone cessation counseling
- Where
- United States
- Volunteers
- 131 people
- Sponsor
- VA Office of Research and Development
Human Health in Extreme Conditions
CHOICE KERGUELEN 2 : Consequences of Longterm Confinement on Immunity in the Sub-Antarctic Islands : Follow-up of Volunteers on the Kerguelen Islands
Living for long periods in extreme environments-like Antarctic research stations or space missions-can have a significant impact on human health, especially on the immune system.
- Trial name
- NCT07275489
- Testing
- blood ponction, urines collection, hair collection
- Where
- French Southern and Antarctic Lands
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Immunity Disorders
Immune Diversity Response to Oral Dosing of Nutritional Health Products in Healthy Participants
A Phase IV, open-label, adaptive, 4-arm, multi-dose, single-centre, exploratory trial to assess the immune diversity response to oral administration of licensed Natural Health Products, in healthy adults, 60-70 years of age.
- Trial name
- NCT05242718
- Testing
- N-Acetyl-L-cysteine (NAC), Echinacea purpurea, Curcumin
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Immunoflex Therapeutics Inc.
Brain Fog, Cognitive Health
Modulation of the Brain Fog Scale by Eicosapentaenoic Acid Monoglycerides (MAG-EPA).
A growing body of studies shows that omega-3s act directly in molecular signaling pathways that reduce inflammation and are thought to have a positive effect on cognitive health.
- Trial name
- NBF-MG01 (NCT06695910)
- Testing
- Monoglyceride Eicosapentaenoic acid (omega-3), Sunflower Oil
- Where
- 2 sites in Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Samuel Fortin
Healthy
Pre-Market Algorithm Validation Study
The study sponsor has developed a patented medical device called Seipher Wellness. This is a non-invasive medical device that assesses heart health based on established cardiac parameters; timing events of the cardiac cycle.
- Trial name
- NCT02200601
- Testing
- Seipher Wellness
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Heart Force Medical Inc.
Caregiver Burnout
Volunteering Program for Chinese Dementia Caregivers
Although many older Chinese Americans are expected to need intensive care because of cognitive impairment, a large gap exists in development of culturally sensitive interventions to reduce stress among caregivers in Chinese…
- Trial name
- NCT04346745
- Testing
- Peer Mentoring Program
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Columbia University
Health Volunteers
The Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]OD-001 in Healthy Male Participants
This study looks at how the body handles an investigational drug called OD-001. Researchers want to learn how the medicine is absorbed, how it is broken down, and how it leaves the body.
- Trial name
- NCT07900607
- Testing
- [14C]OD-001
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Odyssey Therapeutics, Inc.
Malnourished Children
Enhancing Growth Monitoring Visits in Joshipur Rural Municipality, Kailai, Nepal
The goal of this clinical trial is to learn if health workers training on growth promotion and monitoring guideline and Female Community Health Volunteers mobilization for increasing demand for growth monitoring and promotion…
- Trial name
- NCT06743451
- Testing
- Health workers training on GMP guideline, Female community health volunteers' mobilization for inviting mothers and caretakers
- Where
- Nepal
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kathmandu University School of Medical Sciences