Clinical trials: Health Volunteers
Normal Healthy Adults
A Research Study to Evaluate BLX-0871 in Healthy Adults
This study will test an oral medicine called BLX-0871, which is being developed to improve metabolic health by activating AMP-activated protein kinase (AMPK), a key regulator of energy balance.
- Trial name
- NCT07140081
- Testing
- BLX-0871
- Where
- Australia
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Biolexis Therapeutics
Health Volunteer
Pharmacokinetics Impact of HRS-8427 on Bupropion and Midazolam in Healthy Subjects
This study is a single-center, open-label, sequential drug interaction study The primary objectives are: To evaluate the pharmacokinetic effects of HRS-8427 injection on the liver drug enzymes CYP2B6 substrate bupropion and…
- Trial name
- NCT07049107
- Testing
- HRS-8427
- Where
- China
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Healthy
Single Rising Dose Study of BI 135585 XX in Health Asian Male Volunteers.
The Aim of the study is to evaluate safety, tolerability, pharmacokinetics and pharmacodynamics in Asian healthy males administered a single dose of BI 135585.
- Trial name
- NCT01291732
- Testing
- BI 135585 XX
- Where
- South Korea
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Inflammatory Bowel Diseases
Phase 1 Study for IPG11406 in Health Volunteer
A phase 1, randomized, double-blind, placebo-controlled, single and multiple dose escalation study to evaluate the safety, tolerability, pharmacokinetics (PK) and food effect of orally administered IPG11406 in healthy adult…
- Trial name
- NCT06255834
- Testing
- IPG11406
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Nanjing Immunophage Biotech Co., Ltd
Healthy, Cardiovascular Diseases
Effect of Betaine and Folic Acid on Vascular Function in Healthy Humans
The purpose of this study is to determine whether lowering of fasting homocysteine concentrations improves vascular function in healthy volunteers, irrespective of the homocysteine-lowering agent.
- Trial name
- NCT00102843
- Testing
- supplementation with folic acid and betaine
- Where
- Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wageningen Centre for Food Sciences
No Condition. Assessment of Healthy Volunteers.
The Pharmacokinetics and Potential Health Effects of Champagne Wine in Human Subjects
To assess whether acute, moderate Champagne wine consumption modulates endothelial function in healthy human volunteers. To establish the bioavailability of Champagne wine polyphenols and their metabolism.
- Trial name
- NCT00937313
- Testing
- Champagne wine intervention
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Reading
Sleep Disorder (Disorder)
The Effect of NP-2006 on Sleep Quality and Health
The main objective will be to assess the effect of NP-2006 on sleep efficiency in volunteers presented with persistent subclinical insomnia
- Trial name
- NCT07485959
- Testing
- NP-2006
- Where
- South Korea
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Hanpoong Nature Pharm Co., Ltd.
Health Volunteer
A Comparative Pharmacokinetic Study of Single-Dose Administration of HR091506 Tablets From Different Batches in Healthy Subjects
To evaluate the pharmacokinetic characteristics of HR091506 tablets in different batches in healthy subjects after single administration.
- Trial name
- NCT07076459
- Testing
- HR091506 tablet
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Healthy, Stress-related Problem
The Effect of Probiotic Supplementation on Mental Health in Healthy Volunteers
Probiotics are "live microorganisms which when administered in adequate amounts confer a health benefit on the host". Accumulating evidence indicates their effect in mental health restoration.
- Conditions
- Healthy, Stress-related Problem, Depression, Anxiety
- Trial name
- ProBeMent (NCT06391216)
- Testing
- Lactobacillus helveticus R0052 and Bifidobacterium longum R0175
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Medical University of Lodz
Healthy Volunteers, Health
Evaluation of Physical Capacities Within the Company and Effect of a Personalized Versus Traditional Training Program on the Quality of Life of Sedentary Employees
The practice of a physical activity, even moderate, plays an important role in the prevention and the management of the main chronic non-communicable diseases (cardiovascular diseases, certain cancers, diabetes, obesity…
- Trial name
- MOVING_LAB (NCT04998266)
- Testing
- Performing following WHO (World Health Organization), Performing on their needs
- Where
- France
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Health
Phase I Dose-Escalation Study to Evaluate Tolerability, Safety & PK of INO-8875 in Healthy Older-Adult Volunteers
The purpose of this study is to evaluate how tolerable and safe it is to give INO-8875 eye drops at different concentrations to normal older healthy adult volunteers for two weeks.
- Trial name
- NCT01123772
- Testing
- INO-8875
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Inotek Pharmaceuticals Corporation
Chronic Diseases, Hypertension
Collection of Blood and Urine Specimens From Volunteers Utilizing Health Examination Services
In summary, the researchers want to construct a longitudinal data bank using voluntary health examination participants. Researchers in the National Taiwan University Hospital (NTUH) campus can utilize these data to clarify the…
- Conditions
- Chronic Diseases, Hypertension, Diabetes, Obesity
- Trial name
- NCT00173940
- Where
- Taiwan
- Sponsor
- National Taiwan University Hospital
Healthy Volunteers (HV)
Effects of a Sleep Education Program on the Health Status of Healthcare Workers Working 12-hour Alternating Day-night Shifts
In a context of seeking a better balance between personal and professional life and labor shortages, the use of 12-hour alternating day-night shifts has become more common in work organizations, particularly in healthcare…
- Trial name
- SLEEPMORE (NCT07326579)
- Testing
- Sleep educational
- Where
- 3 sites in France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Healthy Volunteer, Mood Disorder
Mental Health Impact of COVID-19 Pandemic on NIMH Research Participants and Volunteers
Background: The COVID-19 outbreak has caused many changes to people s normal social patterns. The respiratory illness has been the major focus of public health efforts.
- Conditions
- Healthy Volunteer, Mood Disorder, Anxiety Disorder, Preexisting Medical Condition
- Trial name
- NCT04339790
- Where
- United States
- Volunteers
- 3,655 people
- Sponsor
- National Institute of Mental Health (NIMH)
Healthy
A Study of Safety, Tolerability, and Pharmacokinetics of Single Ascending Dosed of HSK31858 in Healthy Volunteers
This is a Phase I, single-dose escalation clinical trial for HSK31858 conducted in healthy volunteers. The safety, tolerability, and pharmacokinetics of HSK31858 tablet in healthy volunteers will be evaluated using a randomized…
- Trial name
- NCT05023525
- Testing
- HSK31858, tablet
- Where
- Australia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Haisco Pharmaceutical Group Co., Ltd.
Disaster Medicine, Delivery of Health Care
ESCAPE (Evaluating Surge Capacity And PrEparedness)
The ESCAPE study intends to assess the possibility of recruiting students as surge capacity work force in hospitals in the event of a major medical incident such as an epidemic or pandemic.
- Trial name
- ESCAPE (NCT06144008)
- Testing
- Answering questionnaire
- Where
- Germany
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Smoking Cessation, Nicotine Replacements Therapy
A Study of Nicotine Orodispersible Tablet on Craving Relief of Male and Female Smoker Volunteers
The objective of the study is to evaluate the relief of momentary urge to smoke at pre-specified early post-dose time points after administration of Nic ODT compared to Placebo ODT.
- Trial name
- Zippy PD (NCT07893158)
- Testing
- Nicotine Mint Oro Dispersible Tablet (Nic ODT)
- Where
- Canada
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- McNeil AB
Abuse of Anabolic Steroids
Intranasal Delivery of Testosterone and Its Effect on Doping Markers
Hypothesis: Intranasal administration of exogenous testosterone results in a characteristic profile during anti-doping testing, which is different than the profile seen when testosterone is administered into muscle, on skin or…
- Trial name
- Intranasal (NCT02611154)
- Testing
- Testosterone
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Utah
Chinese Healthy Volunteer
Safety and Pharmacokinetic Study of ARTS-011 in Chinese Healthy Volunteers
This single- and multiple-ascending dose study is a Phase 1, first in human study of ARTS-011. The goal of the study is to assess the safety, tolerability, pharmacokinetics, pharmacodynamics and food effect of ARTS-011 after…
- Trial name
- NCT06260527
- Testing
- ARTS-011
- Where
- China
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Allorion Therapeutics Inc
Health Volunteer
Phase I Clinical Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RSS0343 Tablets in Healthy Subjects After Single and Multiple Oral Administration and the Effect of Food on the Pharmacokinetics of RSS0343
To evaluate the safety and tolerability of RSS0343 tablets in healthy subjects after single and multiple oral administration
- Trial name
- NCT07101965
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.