Clinical trials: Health-Related Behavior
Post-Traumatic Stress Disorder, Depression
Evaluation of Two Community-based Mental Health Interventions for Violence-Displaced Afro-Descendants in Colombia.
This study is a community prevention randomized trial with three parallel groups: two intervention groups and one control group in Buenaventura and Quibdó.
- Conditions
- Post-Traumatic Stress Disorder, Depression, Anxiety, Violence
- Trial name
- ACOPLE (NCT01856673)
- Testing
- Common Elements Treatment Approach, Narrative Community Group Therapy, Standby group
- Where
- 2 sites in Colombia
- Volunteers
- 521 people
- Sponsor
- Universidad del Valle, Colombia
Opioid-use Disorder, Medication Adherence
CoMBAT Opioid Use Disorder: A Combined Medication and Behavioral Activation Treatment for People Living With Opioid Use Disorder
This study seeks primarily to test, in a two-arm randomized controlled trial (RCT), the feasibility, acceptability, and preliminary efficacy of CoMBAT OUD, an intervention that integrates Behavioral Activation (BA) and substance…
- Conditions
- Opioid-use Disorder, Medication Adherence, Health Care Utilization
- Trial name
- CoMBAT_OUD (NCT04240093)
- Testing
- Behavioral Activation (BA) Therapy, Substance Abuse and Health Navigation Counseling, Medications for Opioid Use Disorder
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Brown University
Nicotine Dependence
Evaluation of Moclobemide, a Reversible MAO-A Inhibitor, as an Adjunct to Nicotine Replacement Therapy in Female Smokers
The proposed study will assess the efficacy of moclobemide, a selective, reversible MAO-A inhibitor, in facilitating smoking cessation in treatment-seeking female smokers.
- Trial name
- RIMA (NCT01926626)
- Testing
- Nicotine Patch, Moclobemide
- Where
- 3 sites in United States
- Volunteers
- 76 people
- Sponsor
- Jed E. Rose
Violence, Domestic, Violence-Related Symptom
It's WeWomen Plus Intervention for Health, Safety and Empowerment
This study evaluates the impact of adaptive technology-based intervention (online, text and phone) "weWomenPlus" on safety, mental health and empowerment of abused immigrant women.
- Conditions
- Violence, Domestic, Violence-Related Symptom, Violence, Physical, Violence, Sexual
- Trial name
- IWWP (NCT04098276)
- Testing
- WeWomen Plus technology based intervention
- Where
- United States
- Volunteers
- 1,265 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Inflammatory Bowel Diseases, Depressive Episode
Risk of Mental Health Conditions in Children and Young Adults With Inflammatory Bowel Disease and Influence on Health
This study is a large population-based analysis in the United Kingdom (UK) using routine primary care data to investigate the impacts on quality-of-life outcomes and use of healthcare services in people aged 5 - 25 years…
- Conditions
- Inflammatory Bowel Diseases, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorder
- Trial name
- NCT05206734
- Testing
- No specific intervention
- Where
- United Kingdom
- Volunteers
- 19,469 people, healthy volunteers welcome
- Sponsor
- Momentum Data
HIV/AIDS, Smoking Cessation
Learn to Quit-HIV Pilot Study
The study team will conduct a feasibility, acceptability, and preliminary efficacy trial comparing Learn to Quit-HIV (n=30) to an app based on U.S.
- Conditions
- HIV/AIDS, Smoking Cessation, Tobacco Use Disorder
- Trial name
- NCT04609514
- Testing
- Learn to Quit-HIV, QuitGuide, Nicotine patch
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Duke University
Lung Diseases, Medication Compliance
Uncontrolled Lower Respiratory Symptoms in the WTC Survivor Program
The purpose of this study is to understand why patients in the World Trade Center program have continuing breathing problems. This study will improve investigators understanding of breathing problems among individuals with World…
- Trial name
- NCT02024204
- Testing
- Fluticasone propionate 230mcg for 3 Months, Current Treatment or no treatment, Salmeterol 21mcg for 3 Months
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- NYU Langone Health
Tobacco Use Cessation, Tobacco Use Disorder
Text Messaging for Supporting Quit Attempts
This study is a preliminary research aimed to compare the feasibility and effectiveness of motivational interview (MI), Personalized text messages (TM) and usual care for outpatients, with focus on smoking cessation as the main…
- Trial name
- NCT02571244
- Testing
- Motivational Interview plus text message
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- Federal University of Juiz de Fora
Smoking Cessation, Nicotine Addiction
Circuitry-Guided Smoking Cessation in Schizophrenia
In a double-blinded, randomized, parallel controlled design, patients with schizophrenia spectrum disorder will be exposed to active or sham repetitive transcranial magentic stimulation (TMS) which was guided by functional…
- Conditions
- Smoking Cessation, Nicotine Addiction, Schizophrenia
- Trial name
- NCT03281629
- Testing
- Active TMS stimulation
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Maryland, Baltimore
Schizophrenia, Psychotic Disorders
A Brief Community Linkage Intervention for Dually Diagnosed Individuals
Surveys suggest that up to 80% of veterans with a persistent mental illness have a co-occurring substance use disorder. Substance abuse among this population is problematic and often results in poor engagement in treatment and…
- Conditions
- Schizophrenia, Psychotic Disorders, Substance-Related Disorders, Bipolar Disorder
- Trial name
- TLC (NCT00137267)
- Testing
- Time limited case management, Health Education
- Where
- 2 sites in United States
- Volunteers
- 102 people
- Sponsor
- US Department of Veterans Affairs
Alexithymia, HIV
Role of CBD in Improving Alexithymia
Given the treatments that are available today for HIV disease, people living with HIV (PLWH) can generally expect good medical outcomes.
- Trial name
- ACBD (NCT05832281)
- Testing
- Purysis CBD
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of California, San Diego
Bipolar Disorder
Customized Medication Adherence Enhancement for Treating Adults With Bipolar Disorder
In this study, patients with bipolar disorder who do not take their medications as prescribed will receive specialized education and therapy treatment to determine whether the specialized treatment is effective in helping…
- Trial name
- NCT00763919
- Testing
- Psychoeducation module, Substance abuse module, Improved communication/rapport with provider module
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Case Western Reserve University
Stress Disorders, Posttraumatic, Depression
Re-Engineering Systems for the Primary Care Treatment for PTSD
The study is an evaluation of a systemic intervention to enhance the delivery of care according to practice guidelines for posttraumatic stress disorder (PTSD).
- Trial name
- RESPECT-PTSD (NCT00373698)
- Testing
- Three Component Model of Collaborative Care
- Where
- 4 sites in United States
- Volunteers
- 195 people
- Sponsor
- US Department of Veterans Affairs
Tobacco-Related Carcinoma, Smoking &Amp; Tobacco Cessation
Electronic Quitline Referral With Enhanced Academic Detailing for the Promotion of Smoking Cessation
This phase IV clinical trial determines the impact of implementing a Quitline electronic (e)Referral system with an enhanced academic detailing implementation strategy on Quitline reach, tobacco cessation assistance and…
- Trial name
- CONNECT (NCT04969978)
- Testing
- Enhanced Academic Detailing, Informational Intervention
- Where
- United States
- Volunteers
- 9,133 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Nicotine Dependence
Extended Varenicline Treatment for Smoking Among Cancer Patients
Upwards of 33-50% of cancer patients who smoked prior to diagnosis continue to smoke following diagnosis and treatment. With medical advances in cancer care yielding a growing constituency of cancer survivors, addressing nicotine…
- Trial name
- NCT01756885
- Testing
- Varenicline, Smoking Cessation Counseling
- Where
- 2 sites in United States
- Volunteers
- 207 people
- Sponsor
- University of Pennsylvania
Adverse Drug Reaction
Educational Intervention in Pharmacovigilance for Hospital Health Professionals
Spontaneous reports by health professionals generate the signals in pharmacovigilance. However, the passive method has limitations and the most important of them are the underreporting and the poor quality of data, hindering the…
- Trial name
- EIPhv (NCT02134587)
- Testing
- Multifaceted educational intervention
- Where
- Brazil
- Volunteers
- 203 people
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Smoking Cessation
Behavioral and Enhanced Perinatal Intervention for Cessation (B-EPIC): Reducing Tobacco Use Among Opioid Addicted Women
This study tests an intervention for tobacco cessation (named B-EPIC) in an established community medication assisted treatment (MAT) clinic for pregnant and postpartum women with opioid dependence.
- Trial name
- B-EPIC (NCT03796208)
- Testing
- Behavioral and Enhanced Perinatal Intervention for Cessation (B-EPIC), Treatment As Usual
- Where
- 2 sites in United States
- Volunteers
- 78 people
- Sponsor
- Kristin Ashford
Alzheimer Disease, Dementia
Technology and Family Thriving Study
The purpose of this project is to test the impact of different forms of technology (virtual reality vs. video chat) on quality of life and family relationships in older adults who reside in senior living communities and an adult…
- Conditions
- Alzheimer Disease, Dementia, Caregiver Burnout, Quality of Life
- Trial name
- Thrive (NCT05150990)
- Testing
- Virtual Reality, Video Chat
- Where
- 27 sites in United States
- Volunteers
- 186 people
- Sponsor
- University of California, Santa Barbara
Parenting, Parent-Child Relations
Study of an Online Program to Help Parents Talk With Their Tween Children About Health, Gender, Body-Image, and Relationships
The goal of this study is to learn if Media Aware Parent - Tween, an online program for parents of children ages 9-12, helps parents have effective conversations with their child about health and media.
- Conditions
- Parenting, Parent-Child Relations, Communication
- Trial name
- NCT06408818
- Testing
- Media Aware Parent - Tween, Active Control Resource
- Where
- United States
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- Innovation Research & Training
Tobacco Abstinence
Varenicline For Smokers In Recovery From Alcohol Dependence
The goal of this proposal is to explore the potential effectiveness of varenicline to treat tobacco dependence among recovering alcoholic smokers who, as a group, are at high risk for tobacco-caused morbidity and mortality.
- Trial name
- NCT01092702
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic