Clinical trials: Health-Related Quality of Life
Skeletal Class III Malocclusion
Efficacy of RME and Facemask Therapy for Class III Malocclusion
This multicenter randomized controlled trial compares the efficacy of Rapid Maxillary Expansion (RME) combined with facemask (FM) protraction versus FM protraction alone in treating growing children with skeletal Class III…
- Trial name
- NCT07053683
- Testing
- Combined RME and Facemask Therapy, Facemask Therapy Alone
- Where
- China
- Volunteers
- 358 people
- Sponsor
- Wuhan Integrated Traditional Chinese and Western Medicine Hospital
Breast Cancer
Ethnic Differences in the Impact of Breast Cancer on Employment Status, Financial Situation, and Quality of Life
The purpose of this study is to learn more about how being treated for breast cancer affects patients' employment, financial situation, and quality of life on a short-term basis and on a long term basis.
- Trial name
- NCT01134172
- Testing
- survey web-based or telephone interview
- Where
- 12 sites in United States
- Volunteers
- 935 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Prostate Cancer
Health Related Quality of Life and Multidimensional Evaluations of Prostate Cancer Subjects Aged ≥ 60 Years Initiating Gonadotropin-Releasing Hormone (GNRH) Agonist Therapy
The objective of the study is to compare the evolution over 6 months of Health-Related Quality of Life (HRQOL) among different age groups in subjects with prostate cancer treated with GnRH agonist therapy.
- Trial name
- PRISME (NCT03516110)
- Testing
- Data collection
- Where
- France
- Volunteers
- 831 people
- Sponsor
- Ipsen
Post-intensive Care Syndrome, COVID-19
Clinical and Functional Characteristics of Patients Admitted for Severe COVID-19 Pneumonia
This research protocol aims to evaluate the impact of severe COVID-19 pneumonia requiring invasive mechanical ventilation (IMV) on health-related quality of life (HRQoL), functional capacity, muscle strength, and nutritional…
- Trial name
- EQOL-COVID (NCT06727474)
- Testing
- Health-Related Quality of Life (HRQoL) with EQ-5D-3L
- Where
- Argentina
- Volunteers
- 51 people
- Sponsor
- Hospital Nacional Profesor Alejandro Posadas
Oral Health, Oral Health Related Quality of Life
Oral (Hypo-)Function, General Function and Nutritional Status in Elderly Hospitalized Patients
The goal of this observational study is to learn about the effects of a reduced oral function on the nutritional status of non-acute hospitalized elders and on their oral health quality of life.
- Conditions
- Oral Health, Oral Health Related Quality of Life, Nutrition Disorders in Old Age
- Trial name
- Ohyp (NCT06557226)
- Testing
- oral and nutritional examination
- Where
- 2 sites in Switzerland
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Geneva, Switzerland
Transpalatal Arch (TPA), Oral Health Related Quality of Life (OHRQoL)
Comparing Clinical Application of Innovatedly Made Transpalatal Arch (TPA) From 3D Reconstructed Model and Conventionally Made TPA
Trans-palatal Arch or TPA is an intra oral device that is occasionally used in conjunction of orthodontic fixed appliance treatment. It has two main types, the fixed or removable TPA.
- Conditions
- Transpalatal Arch (TPA), Oral Health Related Quality of Life (OHRQoL), Oral Health Impact Profile Short Version 14 (OHIP 14), Orthodontic Pain
- Trial name
- NCT03755622
- Testing
- Conventional Transpalatal Arch (TPA), Transpalatal Arch (TPA) fabricated from 3D reconstructed model
- Where
- Malaysia
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Lung Cancer, Non Small Cell Lung Cancer
Routine Electronic Monitoring Of Quality Of Life -Poumon (REMOQOL-Poumon)
Routine electronic monitoring of health-related quality of life (REMOQOL) consists of collecting HRQoL patients' data via an electronic device in order to provide these data to healthcare providers.
- Trial name
- NCT04857970
- Testing
- Electronic HRQoL questionnaires with feedback to physicians, Paper-pencil HRQoL questionnaires w.o. feedback to physicians
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Pain, Postoperative, Quality of Life
Efficacy of Two Local Anesthetics on Quality of Life After Endodontic Treatment
In this randomized controlled double-blinded study, subjects will be assigned to one of two study groups to either be anesthetized with Bupivacaine or Lidocaine prior to needed treatment of pulpectomy/endodontic debridement on a…
- Trial name
- B-OHIP14 (NCT04787731)
- Testing
- Bupivacaine Local Anesthetic
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- NYU College of Dentistry
Cerebral Palsy, Quality of Life
Health Related Lifestyle and Quality of Life in Children With Cerebral Palsy
The primary aim of this study is assessing physical activity, the quality of sleep and health related quality of life in children with cerebral palsy, and parenting stress of caregivers of the children with cerebral palsy in…
- Conditions
- Cerebral Palsy, Quality of Life, Physical Activity, Physical Disability
- Trial name
- NCT03277027
- Testing
- interventional study
- Where
- South Korea
- Volunteers
- 62 people
- Sponsor
- The Catholic University of Korea
Children's Wellbeing, Child Overall Health Related Quality of Life
Let´s Talk About Children Intervention in a School Context
The aim of this study is to examine the fidelity, the perceived benefits, and the effectiveness of the Let's Talk about Children (LTC) -intervention in a school context.
- Conditions
- Children's Wellbeing, Child Overall Health Related Quality of Life, Burnout
- Trial name
- NCT05038280
- Testing
- Let's Talk about Children intervention
- Where
- Finland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Physical Activity, Obesity
Effectiveness of a Physical Activity Intervention to Prevent Obesity and Improve Academic Performance
Coordinated project whose objectives are: a) to test the effectiveness of a promotion of physical activity intervention (MOVI-KIDS) on preventing obesity; and b) to improve the academic performance in both children with and…
- Conditions
- Physical Activity, Obesity, Children, Academic Underachievement Disorder
- Trial name
- MOVI-KIDS (NCT01971827)
- Testing
- MOVI-KIDS
- Where
- Spain
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Prostate Cancer
Comparison of Between ThinSeed™ and OncoSeed™ for Permanent Prostate Brachytherapy
This study will investigate health related quality of life factors in patients undergoing low dose rate prostate brachytherapy. Patients will be randomized to Iodine-125 Thinstrand (for use with 20 g needles) or Rapidstrand (for…
- Trial name
- NCT01379742
- Testing
- RapidStrand seeds for use with 18g needle, ThinStrand
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Prostate Cancer Foundation of Chicago
Health Behavior, Health-Related Behavior
Preventive Remediation for OptiMal StudentS (PROMESS-Group)
Health students exhibit excessive sedentary behavior, elevated stress levels, and significant sleep disturbances, all of which contribute to a decline in their overall health, quality of life, and learning capacities.
- Trial name
- PROMESS-Group (NCT07030751)
- Testing
- Stress management, sleep improvement and fatigue reduction, sedentary behaviors reduction and physical activity promotion.
- Where
- France
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Research on Healthcare Performance Lab U1290
Refractory Ischemia
Quality of Life in Patients With Refractory Angina
The health and well being of patients with refractory angina will be assessed using validated questionnaires (SF-36 and Seattle Angina Questionnaire [SAQ]) at baseline and one year.
- Trial name
- NCT00840437
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Minneapolis Heart Institute Foundation
Cardiovascular Diseases, Hypertension
IV Hydrogen Nanobubbles for Cardiac Function and QoL
The goal of this clinical trial is to learn if intravenous hydrogen nanobubbles (HNBs) improve cardiovascular function and quality of life in adults.
- Conditions
- Cardiovascular Diseases, Hypertension, Blood Pressure
- Trial name
- HNB (NCT07085637)
- Testing
- intravenous infusion of hydrogen nanobubbles (HNB) administered twice weekly over a 5-week period
- Where
- Indonesia
- Volunteers
- 52 people
- Sponsor
- Indonesia Molecule Institute
Age-related Hearing Loss
Increasing Physical Activity with a Social Robot-assisted Exercise Intervention in Older Adults with Hearing Loss: a Feasibility and Pilot Randomized Controlled Trial
Objectives To assess the feasibility and acceptability of using a home-based, social robot-assisted intervention (SRAI) for older adults with hearing loss (HL), and to examine the preliminary effects of SRAI on improving physical…
- Trial name
- NCT06878339
- Testing
- A social robot KaKa-assisted intervention
- Volunteers
- 40 people
- Sponsor
- The Hong Kong Polytechnic University
Health-Related Quality-of-Life, Adolescent
HEALTH-RELATED QUALITY OF LIFE IN CEREBRAL PALSY: AGREEMENT BETWEEN ADOLESCENTS, CAREGIVERS AND PHYSIOTHERAPISTS
Health-related quality of life (HRQoL) has recently become a widely used outcome measure. Although self-reporting is considered the gold standard, proxy reports are commonly used for adolescents with cerebral palsy (CP).
- Conditions
- Health-Related Quality-of-Life, Adolescent, Cerebral Palsy (CP)
- Trial name
- NCT07211594
- Where
- Turkey (Türkiye)
- Volunteers
- 97 people
- Sponsor
- Hacettepe University
Rheumatic Conditions
Health Economic Impact of Steroids
Three focus groups will be conducted with patients who have an inflammatory rheumatic condition and have been treated with steroids in the last three years to discuss the impact of steroids on their quality of life, the financial…
- Trial name
- HEIST (NCT07863245)
- Testing
- This is a qualitative focus group study therefore no interventions planned
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- University of the West of England
Oral Health Related Quality of Life (OHRQoL)
Validation of a French Version of the OHIP - Oral Health Impact Profile
The primary objective of this study is therefore to propose and validate a French-language (France) version of the OHIP (49 questions) (OHIP-fr-49: long version), and the secondary objective is to validate a shortened version…
- Trial name
- OHIP (NCT07482293)
- Testing
- OHIP
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Clermont-Ferrand
Discolored Teeth
In-office and At-home Tooth Bleaching Using Low Concentration Peroxides.
To evaluate the efficacy, safety and impact on quality of life related to oral health of home and office tooth whitening techniques in young individuals.
- Trial name
- NCT02816593
- Testing
- hydrogen peroxide 6%, hydrogen peroxide 15%, Carbamide Peroxide 10%
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais