Clinical trials: Health-related Quality of Life
Pulmonary Disease, Chronic Obstructive
Targeted Nutrient Supplement in COPD (NUTRECOVER-trial)
The overall objective is to investigate the efficacy of targeted nutrient supplementation on daily physical activity level as well as generic health status in patients with COPD.
- Trial name
- NUTRECOVER (NCT03807310)
- Testing
- Targeted nutrient supplementation (Long-drink), Counselling
- Where
- Netherlands
- Volunteers
- 166 people
- Sponsor
- Maastricht University Medical Center
Caregiver Stress Syndrome
The Caregiver Pathway - An Intervention to Support Caregivers of Critically Ill Patients
The aim of the project is to test the efficacy of a systematic intervention for individual follow-up of caregivers at the intensive care unit during a 12 month randomized controlled trial.
- Trial name
- NCT04839406
- Testing
- Structured support of caregivers at the ICU
- Where
- Norway
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Hazardous Drinking
Primary Care-based Facilitated Access to a Web Based Brief Intervention to Reduce Alcohol Consumption
Brief Interventions (BIs) for risky drinkers are an effective tool in primary care. Lack of time in daily practice has been identified as a barrier for the wide implementation of BI.
- Trial name
- EFAR-Spain (NCT02082990)
- Testing
- Face-to-Face Brief Intervention, Online Brief Intervention
- Where
- Spain
- Volunteers
- 320 people
- Sponsor
- Hospital Clinic of Barcelona
Glioblastoma, Radionecrosis of Brain
FET-PET-Guided Management of Pseudoprogression in Glioblastoma
The goal of this diagnostic randomised clinical trial is to determine, in glioblastoma patients with diagnostic uncertainty between pseudoprogression and tumor progression on follow-up MRI after chemoradiation, the added value of…
- Trial name
- FET-POPPING (NCT06480721)
- Testing
- Clinical management based on the index MRI and an additional [¹⁸F] FET PET scan
- Where
- 8 sites in Netherlands
- Volunteers
- 144 people
- Sponsor
- Veerle Ruijters
Postoperative Pain After Endodontic Treatment, Oral Health-Related Quality of Life
Effects of Different Root Canal Filling Materials and Irrigation Agitation Techniques on Postoperative Pain in Teeth With Irreversible Pulpitis: A Randomized Clinical Trial
This clinical study is designed to evaluate the effects of different irrigation agitation techniques and root canal sealers on postoperative pain and oral health-related quality of life in patients with symptomatic irreversible…
- Conditions
- Postoperative Pain After Endodontic Treatment, Oral Health-Related Quality of Life, Symptomatic Irreversible Pulpitis, Endodontic Treatment
- Trial name
- NCT07859384
- Testing
- XP-Endo Finisher, EDDY, Passive Ultrasonic Activation
- Where
- Turkey (Türkiye)
- Volunteers
- 324 people
- Sponsor
- Ankara University
Chronic Illness
Development and Implementation of Evidence-Based Family-Oriented Support for Young Carers and Their Families in Germany
The purpose of this study is to develop and implement evidence-based and family-oriented support for young carers and their families in Germany.
- Trial name
- NCT00734942
- Testing
- support service
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- University of Witten/Herdecke
Myelodysplastic Syndromes
Sterile Inflammation and Molecular Aberrations in MDS
The objective of this study is the description of the possible association between genetic mutation/aberration profiles, inflammatory tonus and clinical phenotype based on PROMs and HRQoL.
- Trial name
- InflamGen (NCT04313231)
- Testing
- Next Generation Sequencing, Tumorimmunological examinations - multiplex assays/quantitative polymerase chain reaction, flow cytometry
- Where
- Austria
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Friedreich Ataxia
Patient-reported, Health Economic and Psychosocial Outcomes in Friedreich Ataxia
The PROFA study is an international, multi-centric observational and validation study to assess the patient-reported, psychosocial and economic outcomes of patients with Friedreich Ataxia (FA).
- Trial name
- PROFA (NCT05943002)
- Where
- 6 sites in Austria, France and 1 more
- Volunteers
- 200 people
- Sponsor
- German Center for Neurodegenerative Diseases (DZNE)
Hepatic Encephalopathy
Therapeutic Efficacy of Oral L-Ornithine-L-Aspartate on Minimal Encephalopathy
The study aimed to assess the effectiveness and safety of L-ornithine-L-aspartate in the management of hepatic encephalopathy.
- Trial name
- PORTOALEGRE (NCT00896831)
- Testing
- L-ornithine-L-aspartate
- Where
- Brazil
- Volunteers
- 96 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Fibromyalgia
Comparison of Lymph Drainage and Connective Tissue Massage in Fibromyalgia Patients
The present study was designed to analyze and compare the effects of Manual Lymph Drainage Therapy and Connective Tissue Massage in females with Fibromyalgia (FM).
- Trial name
- FM (NCT00635895)
- Testing
- Manual Lymph Drainage Therapy and Connective Tissue Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Pamukkale University
Chronic Obstructive Pulmonary Disease
Exacerbations and Health Related Quality of Life in Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) exacerbation is a major cause of physician visits and hospital admissions associated with acute respiratory failure, causing increased morbidity and premature mortality and thus it can…
- Trial name
- NCT00884975
- Volunteers
- 102 people
- Sponsor
- University of Thessaly
Physical Disability, Depression
Prognostication of Need for Rehabilitation and Special Support in ICU Survivors
Title: PROGnostication of need for REhabilitation and Special Support after Intensive Care Unit Stay - a multinational, observational study Objectives: 1.
- Conditions
- Physical Disability, Depression, Posttraumatic Stress Disorder, Anxiety
- Trial name
- PROGRESS-ICU (NCT02679157)
- Where
- 10 sites in Denmark, Netherlands and 1 more
- Volunteers
- 573 people
- Sponsor
- Karolinska University Hospital
Older People
The FINGER Model - Preventing Cognitive Decline and Promoting Health of Older People.
Cognitive impairment and dementia can cause considerable suffering, both for the person affected and for next of kin. They also pose major challenges for health and social care.
- Trial name
- NCT07661472
- Testing
- FINGER model
- Where
- Sweden
- Volunteers
- 180 people
- Sponsor
- University of Gavle
Anal Cancer
Quality of Life in Patients With Anal Cancer
A national study of a three year cohort consisting of all patients diagnosed with anal cancer in 2011- 2013 with data retrieval from three national registries: Cancer Registry, Patient registry and Cause of Death Registry all…
- Trial name
- ANCA (NCT02546973)
- Where
- Sweden
- Volunteers
- 300 people
- Sponsor
- Sahlgrenska University Hospital
VEXAS
HRQoL and Financial Toxicity in Patients With VEXAS Syndrome
This multicenter cross-sectional observational study aims to describe health-related quality of life (HRQoL) and symptom profiles of patients with VEXAS syndrome.
- Trial name
- NCT06657846
- Where
- 17 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Gruppo Italiano Malattie EMatologiche dell'Adulto
Psychological Adaptation, Psychological Adjustment
QOL and GI Outcomes in Malignancies
The purpose of this research is to evaluate a new, web-based program among patients with pancreatic cancer aimed at reducing psychosocial stress.
- Conditions
- Psychological Adaptation, Psychological Adjustment, Stress, Emotional
- Trial name
- NCT04815746
- Testing
- Cognitive Behavioral Therapy (CBT)-based skills, Standard Education
- Where
- United States
- Sponsor
- University of Miami
Cancer, Cancer, Treatment-Related
Oncotool for Cancer Medications
The purpose of this study is to examine the efficacy of a psychosocial eHealth intervention on the proposed primary outcomes, TKI adherence and health related quality of life (HRQoL), in patients taking TKIs for cancer…
- Conditions
- Cancer, Cancer, Treatment-Related, Medication Adherence, Communication
- Trial name
- NCT03952312
- Testing
- Oncotool Intervention (symptom reporting + TKI education), Oncotool Control (health information)
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Northwestern University
Constipation
An Observational Study to Evaluate the Quality of Life in Korean Female Participants With Chronic Constipation
The purpose of this observational study is to investigate health related quality of life (QoL) in Korean female participants with chronic constipation (long term decreased number of or difficulty making bowel movements) having…
- Trial name
- NCT01902537
- Testing
- Prucalopride; observational study
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Janssen Korea, Ltd., Korea
Anemia
The Effect of PROCRIT (Epoetin Alfa) on Postoperative Vigor and Handgrip Strength (VIGOR Study)
The purpose of this study was to compare the effect of epoetin alfa to preoperative autologous blood donation (PAD) on postoperative vigor (a measure of functional ability and well-being) and handgrip strength in patients…
- Trial name
- NCT00401869
- Testing
- Epoetin alfa
- Volunteers
- 289 people
- Sponsor
- Ortho Biotech, Inc.
Adolescent Idiopathic Scoliosis
Memory and Scoliosis Spinal Exercises
This is a behavioral observational study aimed at evaluating the impact that spinal exercises exert on memory of young people. It consists of a short self-administered questionnaire which will be given to adolescents with…
- Trial name
- NCT05969301
- Testing
- Specific spinal exercises for idiopathic scoliosis
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- International Institute of Behavioral Medicines
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