Clinical trials: Health-related Quality of Life
Cancer, Chronic Pain Due to Malignancy (Finding)
Safety and Efficacy of Smoked Cannabis for Improving Quality of Life in Advanced Cancer Patients
Cancer causes pain in many of the patients that it affects. Physicians specialized in palliative care help advanced cancer patients to maintain as good pain control as possible through the use of medications such as opioids.
- Trial name
- NCT03339622
- Testing
- PPP001
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- Tetra Bio-Pharma
Dementia
A Virtual Reality at Home Intervention for People Living With Dementia
The goal of the current study is to design and evaluate a virtual reality (VR) at-home intervention to facilitate communication between persons living with dementia (PLwD) and their family/friend care partners, and in turn…
- Trial name
- VRx@Home (NCT06568211)
- Testing
- Virtual Reality, Tablet-Only
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University Health Network, Toronto
Epilepsy
A Novel Social Emotional Learning Curriculum for Youth With Epilepsy
Youth with epilepsy (YWE) are significantly more likely than their peers without epilepsy to experience isolation, interpersonal victimization, and low relationship satisfaction. This is a serious health concern.
- Trial name
- NCT06427967
- Testing
- Project Dream Team
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Boston Medical Center
Depression and Quality of Life
ICBT for Mental Health Problems Related to the Climate Crisis
The study seeks to investigate the effects of a guided internet-based cognitive behavioral therapy (ICBT) programme on adult mental health problems related to the climate crisis.
- Trial name
- NCT05169736
- Testing
- Cognitive Behavioural Therapy
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Linkoeping University
Minimal Hepatic Encephalopathy, Hepatic Encephalopathy
Effect of Lactulose on Minimal Hepatic Encephalopathy and Health-Related Quality of Life
Minimal hepatic encephalopathy (MHE) has a negative effect on patients' daily functioning. No study has so far investigated the effect of treatment related improvement in cognitive functions on health related quality-of-life…
- Trial name
- NCT00375375
- Testing
- Lactulose
- Where
- India
- Volunteers
- 80 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Radiation Toxicity, Chemotherapeutic Toxicity
Patients Referred to the Chronic Pain Unit for Palliative Treatment With Ozone Therapy Between 2022 and 2025
The main objective of this study is to analyze the impact on the health-related quality of life of patients with refractory symptoms, who have been referred to the HUGCDN Chronic Pain Unit for adjuvant palliative treatment with…
- Conditions
- Radiation Toxicity, Chemotherapeutic Toxicity, Chemotherapy-induced Peripheral Neuropathy, Delayed Wound Healing
- Trial name
- EPOOzo (NCT05417737)
- Testing
- Ozone therapy
- Where
- Spain
- Volunteers
- 105 people
- Sponsor
- Bernardino Clavo, MD, PhD
Intrahepatic Cholestasis of Pregnancy, Genetic Mutation
Bile Acids Metabolism and Genetic Mutation Profile in the Intrahepatic Cholestasis of Pregnacy in Indian Population
Intrahepatic cholestasis of pregnancy (ICP) is a disorder characterized by itching, elevated fasting serum bile acids ≥10μmol/L (and elevated serum transaminases), with increased risks of perinatal complications, including…
- Conditions
- Intrahepatic Cholestasis of Pregnancy, Genetic Mutation, Health Related Quality of Life
- Trial name
- ICP (NCT05691036)
- Where
- India
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Orofacial Pain, Sleep Bruxism
Orofacial Pain and Oral Health-Related Quality of Life in Musicians in German Amateur Orchestras
This cross-sectional online survey investigates the prevalence of orofacial pain, sleep-related problems, and oral health-related quality of life (OHRQoL) among adult musicians who play in German amateur orchestras.
- Conditions
- Orofacial Pain, Sleep Bruxism, Oral Health Related Quality of Life (OHRQoL)
- Trial name
- OSQ-MUS (NCT07714837)
- Testing
- Questionaire
- Where
- Germany
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University Medical Center Goettingen
Gastrointestinal Neuroendocrine Tumours
Quality-Of-Life QLQ-GINET21 Questionnaire In The Treatment Of Patients With Gastrointestinal Neuroendocrine Tumours
The purpose of this study is to evaluate the utility of the QLQ-GINET21 in making clinical and therapeutic decisions.
- Trial name
- QUALINETS (NCT02853422)
- Where
- 32 sites in Portugal, Spain
- Volunteers
- 199 people
- Sponsor
- Ipsen
Metastatic Malignant Female Reproductive System Neoplasm
Single Fraction or Multi-fraction Palliative Radiation Therapy for the Improvement of Quality of Life in Patients With Metastatic Gynecologic Cancers
This phase II trial studies if a single session of palliative radiation therapy can help improve symptoms of gynecologic cancers that have spread to other places in the body (metastatic) and that affect quality of life as well or…
- Trial name
- NCT04516135
- Testing
- 3-Dimensional Conformal Radiation Therapy, Intensity-Modulated Radiation Therapy, Quality-of-Life Assessment
- Where
- 3 sites in United States
- Volunteers
- 28 people
- Sponsor
- M.D. Anderson Cancer Center
Quality of Life, Family Relations
Family to Family: Psychoeducation to Improve Children's Outcomes in HIV+ Families
This project aims to support adults in HIV-affected families in order to improve their well-being. UCLA's Center for Community Health (CCH), in collaboration with the Thai Ministry of Public Health, Bureau of Epidemiology, will…
- Conditions
- Quality of Life, Family Relations, Mental Health, Physical Health
- Trial name
- NCT01037946
- Testing
- Cognitive behavioral sessions
- Where
- United States
- Volunteers
- 1,033 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Amyotrophic Lateral Sclerosis, Motor Neuron Disease
Effects of Long Term Ventilation Support on the Quality of Life of ALS Patients and Their Families
Amyotrophic lateral sclerosis (ALS) is a serious rapidly progressive disease of the nervous system. The average survival from the time of diagnosis is two to three years.
- Conditions
- Amyotrophic Lateral Sclerosis, Motor Neuron Disease, Nervous System Diseases, Spinal Cord Diseases
- Trial name
- ALS-LTMV (NCT05744310)
- Testing
- Long term mechanical ventilation support, No long term mechanical ventilation support
- Where
- 9 sites in Norway
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Atrial Fibrillation Paroxysmal
Physiotherapist-led Exercise Within Cardiac Rehabilitation and Paroxysmal Atrial Fibrillation and COVID-19.
Paroxysmal atrial fibrillation (AF) induce, in the affected patient, a prominent negative effect on health-related quality of life (HR-QoL) and physical fitness.
- Trial name
- NCT04600713
- Testing
- PT-X and IMT
- Sponsor
- Vastra Gotaland Region
Aortic Stenosis, Anxiety
10-year Follow-up After Aortic Valve Replacement Surgery
There is a lack of data on patients self-reported outcomes (PROMs) on health-related quality of life (HRQoL)and symptoms on anxiety and depression 10 years after Surgical After Aortic Valve Replacement (SAVR), and patient…
- Conditions
- Aortic Stenosis, Anxiety, Depressive Symptoms, Quality of Life
- Trial name
- AVR-10year (NCT06255691)
- Volunteers
- 282 people
- Sponsor
- Oslo University Hospital
Anxiety and Fear
Memory and Fear Study (Fear of Memory Loss Study)
This study is a randomized control study to determine the impact of a tailored, web-based mindfulness program to reduce anxiety and increase the quality of life in older adults experiencing dementia-related fears, relative to a…
- Trial name
- NCT04821960
- Testing
- Tailored Mindfulness Program for Fear of Memory Loss, Conventional Mindfulness Program
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Postmenopausal Women
Effect of High Cocoa Content Chocolate on Health in Postmenopausal Women.
This is a randomized clinical trial aimed at postmenopausal women aged 50 to 64 years old selected in urban primary care centers of two centers (Spain).
- Trial name
- NCT03492983
- Testing
- Intervention group
- Where
- Spain
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Investigacion y Formacion en Ciencias de la Salud
Oral Disease, Food Selection
Oral Health-related Patterns of Food Selectivity in Dental Populations
The present study was undertaken in order to describe the clinical profiles of food selective behavior in 35-65 years dental and non-dental populations.
- Trial name
- NCT06140654
- Testing
- Clinical oral examination, Food behavior
- Where
- France
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Hôpital Rothschild
Cancer, Breast, Cancer-related Problem/Condition
A Research Study for Latina Women With Breast Cancer
The purpose of this study is to examine the feasibility and preliminary efficacy of a psychosocial eHealth intervention designed to improve hormone therapy adherence among Hispanic/Latinx women with breast cancer.
- Conditions
- Cancer, Breast, Cancer-related Problem/Condition, Quality of Life, Hormone Dependent Neoplasms
- Trial name
- NCT04861896
- Testing
- "My Guide" (psychoeducation & self-management program)
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Northwestern University
Oral Habits
A Clinical Comparative Study of Different Methods for Correcting Lower Lip Sucking Habits in Preschool Children
Comparison of the Effectiveness of Behavioral Therapy, Maxillary Lip Bumper Appliance, and Twin-Block Appliance in Correcting Lower Lip Sucking Habits in Children
- Trial name
- NCT06650241
- Testing
- Behavioral therapy, Lip Bumper Therapy, Modified Twin-Block Therapy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Qingdao University
Stroke
Quality of Life After Stroke Using a Telemedicine-based Stroke Network
To study the effect of a telemedicine model of stroke care on patient-based outcomes.
- Trial name
- STROKE TeleQOL (NCT02447094)
- Testing
- Alteplase
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Thomas Jefferson University
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