Clinical trials: Health-related Quality of Life
Aortic Stenosis, Anxiety
10-year Follow-up After Aortic Valve Replacement Surgery
There is a lack of data on patients self-reported outcomes (PROMs) on health-related quality of life (HRQoL)and symptoms on anxiety and depression 10 years after Surgical After Aortic Valve Replacement (SAVR), and patient…
- Conditions
- Aortic Stenosis, Anxiety, Depressive Symptoms, Quality of Life
- Trial name
- AVR-10year (NCT06255691)
- Volunteers
- 282 people
- Sponsor
- Oslo University Hospital
Childhood Solid Tumor
Comparing the Impact of Cancer on Quality of Life Between Survivors of Childhood Solid Tumors and Leukemia
The aim of the study is to examine the impact of cancer and treatment-related effects on the physical and psychosocial well-being and quality of life among Hong Kong Chinese survivors of childhood solid tumors.
- Trial name
- NCT03430752
- Testing
- questionnaires
- Where
- Hong Kong
- Volunteers
- 135 people
- Sponsor
- The University of Hong Kong
Critical Illness, PICS
ICU Follow-up After Prolonged Intensive Care Stay
Treatment in the intensive care unit (ICU) for more than five days often leads to chronic physical, cognitive and psychological complaints, such as post-traumatic stress disorders, muscle weakness, depression, anxiety and…
- Conditions
- Critical Illness, PICS, Post Intensive Care Syndrome
- Trial name
- PINA (NCT04186468)
- Testing
- ICU follow-up clinic
- Where
- 3 sites in Germany
- Volunteers
- 40 people
- Sponsor
- Otto-von-Guericke University Magdeburg
Fibromyalgia
Improvement of the Health-related Quality of Life of Patients With Fibromyalgia Using Multidisciplinary Treatment
The purpose of this study is to assess improvement in health related quality of life of fibromyalgia patients following 6 weeks of interdisciplinary treatment compared to the usual treatment.
- Trial name
- NCT01266733
- Testing
- Interdisciplinary treatment, Interdisciplinary treatment of fibromyalgia
- Where
- Spain
- Volunteers
- 153 people
- Sponsor
- Hospital Galdakao-Usansolo
Head and Neck Cancer, Skull Base--Cancer
HRQoL in Patients With Solid Tumors Treated With Hadrontherapy
The Quality of Life of patients treated with hadrontherapy is still limited. Two cohorts are established, they will be receiving specific standardized questionnaires to be evalutaed in their results.
- Conditions
- Head and Neck Cancer, Skull Base--Cancer, Brain Cancer
- Trial name
- HadroQoL (NCT05947149)
- Testing
- questionnaires administration
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- CNAO National Center of Oncological Hadrontherapy
Chronic Infectious Disease, Chronic Skin Disease
Relationships Among Inflammation, Physical and Mental Health in Subjects With Chronic Inflammatory Physical Diseases.
The prevalence of common mental disorders is high in patients with chronic inflammatory physical diseases(e.g., autoimmune or infectious diseases).
- Conditions
- Chronic Infectious Disease, Chronic Skin Disease, Mental Disorders, Psoriasis
- Trial name
- InflaMent (NCT05125458)
- Where
- Italy
- Volunteers
- 93 people
- Sponsor
- University of Campania Luigi Vanvitelli
HIV Infection
A Study of Health-Related Quality of Life in HIV-Infected Patients Undergoing Structured Treatment Interruptions of Highly Active Antiretroviral Therapy
This study will examine and compare the health-related quality of life and degree of symptom discomfort in two groups of patients receiving intensive drug therapy for HIV infection.
- Trial name
- NCT00001948
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Congenital Adrenal Hyperplasia
Qualitative Research on Women With Congenital Adrenal Hyperplasia
This qualitative interview-based study will investigate the impact that living with congenital adrenal hyperplasia has for women in the following areas: health-related quality of life (HRQL), psychological health, and…
- Trial name
- CAH (NCT00559078)
- Testing
- Interview
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Lehigh University
Loneliness, Depression
A Pilot Study to Examine the Impact of a Therapy Dog Intervention on Loneliness and Related Health Outcomes in Vulnerable Populations
The purpose of this research study is to test whether an animal-assisted interaction (AAI) intervention is better than conversation with another person or treatment as usual for improving mood, anxiety, loneliness, quality of…
- Conditions
- Loneliness, Depression, Anxiety, Quality of Life
- Trial name
- NCT05089201
- Testing
- Animal-assisted interaction, Conversational control
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Virginia Commonwealth University
Preoperative Anxiety Experienced by the Patient
Effect of Viewing a Standardized Surgical Procedure Video on Preoperative Anxiety in Women Undergoing Benign Hysterectomy
Preoperative anxiety is common among women undergoing hysterectomy and may adversely affect perioperative outcomes and patient experience.
- Trial name
- SHARE (NCT07741019)
- Testing
- Viewing a Surgical Procedure Video, Standard Preoperative Counseling
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Hacettepe University
Oral Hygiene, Self-Management
Effect of Health Diary on Self-management in Adolescent Patients With Fixed Orthodontic Appliance
This study aims to use two-arm randomized clinical trials to evaluate the effectiveness of the health diary in helping adolescents wearing fixed orthodontic appliances improve their oral hygiene status, self-management skills…
- Trial name
- NCT06461611
- Testing
- Health Diary Program, Traditional Health Education
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Wei XIA, PhD
Mental Health Issue, Substance Use Disorders
Co-Active Therapeutic Theatre (Co-ATT) for Dual-Diagnosis Patients
Drama Therapy involves of the use of theatrical techniques (such as script development, acting exercises, improvisation, etc.) to help treat patients' mental illness and improve their functioning and overall sense of wellbeing.
- Trial name
- Co-ATT (NCT06187701)
- Testing
- Co-Active Therapeutic Theatre (Co-ATT)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Boston Medical Center
Diabetes Mellitus, Type 1
Pilot Study of Brief Intervention to Support Diabetes Health-Related Quality of Life
The aims of this pilot study are to evaluate the feasibility, acceptability, preliminary impact, and costs of a brief, behavioral intervention delivered remotely by diabetes educators to people with type 1 diabetes and their…
- Trial name
- T1DALPilot (NCT05234944)
- Testing
- Type 1 Diabetes and Life
- Where
- 3 sites in United States
- Volunteers
- 120 people
- Sponsor
- Baylor College of Medicine
Tooyh Discoloration
Impact of At-Home Dental Bleaching on Quality of Life Using OHIP-14
This prospective clinical study aims to evaluate the clinical efficacy of an at-home dental bleaching protocol and its impact on oral health-related quality of life using objective color measurements and patient-reported…
- Trial name
- WID-OHIP (NCT07624344)
- Testing
- Carbamide peroxide 16%
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Rheumatoid Arthritis
Health-related Quality of Life and Patient-reported Outcomes in Rheumatoid Arthritis Patients Treated With Certolizumab Pegol
The main objective is to assess Health-Related Quality of Life (HRQoL) according to physical function, as measured by a specific Questionnaire (Health Assessment Questionnaire), in Rheumatoid Arthritis (RA) patients who begin…
- Trial name
- SONAR-12 (NCT01526434)
- Where
- 15 sites in Spain
- Volunteers
- 81 people
- Sponsor
- UCB Pharma SA
Crohn Disease, Colitis, Ulcerative
Improving the Health Care in Inflammatory Bowel Disease.
Inflammatory Bowel Disease (IBD) refers to two chronic diseases (Crohn's disease and Ulcerative colitis) both complex disorders requiring a long-term management, with significant healthcare resource consumption.
- Trial name
- NCT02770599
- Testing
- IBD multidisciplinary team model including IBD nurse
- Where
- Norway
- Volunteers
- 304 people
- Sponsor
- University Hospital of North Norway
Cancer-related Problem/Condition, Cancer-related Fatigue
Engagement and Acceptability of the Untire mHealth App
The aim of this study will be to assess the engagement and acceptability of the Untire mHealth intervention for adults with cancer related fatigue. Acceptability will be assessed after 2, 4, 6 and 12 weeks of app use.
- Trial name
- NCT05891431
- Testing
- Untire mobile app
- Where
- 2 sites in United Kingdom
- Volunteers
- 34 people
- Sponsor
- University of Bath
Arrhythmias, Cardiac, Heart Failure, Systolic
Reasons for Variations in Health Related Quality of Life and Symptom Burden in Patients With Atrial Fibrillation
Atrial fibrillation is the most common cardiac arrhythmia. There is a large variation in symptoms; from almost none to severe but the reason for this is unclear.
- Conditions
- Arrhythmias, Cardiac, Heart Failure, Systolic, Atrial Fibrillation
- Trial name
- SMURF (NCT01553045)
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- University Hospital, Linkoeping
Molar Incisor Hypomineralization
Change in OHRQOL Following Minimally Invasive Treatment of Anterior Teeth in Children With MIH
MIH is a prevalent developmental defect which has a negative impact on children's OHRQoL, especially when incisor opacities are present.
- Trial name
- NCT05727475
- Testing
- Minimal invasive restorative treatment, Fluoride gel application
- Where
- Jordan
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Paediatrics With Cataracts, Paediatrics With Glaucoma
Quality of Life in Children Glaucoma and Cataract
The management of childhood glaucoma (CG), childhood cataract (CC) and other birth defects affecting the eyes requires frequent hospital attendances and often multiple surgical and medical interventions, and are often associated…
- Trial name
- NCT02490267
- Testing
- Quality of Life questionnaire
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Moorfields Eye Hospital NHS Foundation Trust
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