Clinical trials: Health-related Quality of Life
Parkinson Disease
Efficacy and Safety or Rhythmic Auditory Stimulation (RAS) for Gait and Balance Disorders in Parkinson's Disease
Gait deficits are among the most characteristic and most functionally debilitating signs of the motor neuropathology of Parkinson's disease (PD).
- Trial name
- ERA-EP2 (NCT03278639)
- Testing
- Rhythmic Auditory Stimulation, Kinesiology
- Sponsor
- Pontifical Catholic University of Argentina
Dental Caries, Gingivitis
Parental Perception of Oral Health-Related Quality of Life in Sudanese Refugee vs. Egyptian Children
This cross-sectional analytical study aims to assess and compare parental perceptions of oral health-related quality of life (OHRQoL) among Sudanese refugee children and Egyptian children aged 6-12 years living in Egypt.
- Conditions
- Dental Caries, Gingivitis, Oral Health, Refugee Health
- Trial name
- NCT07011381
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Pain, Postoperative, Quality of Life
Efficacy of Two Local Anesthetics on Quality of Life After Endodontic Treatment
In this randomized controlled double-blinded study, subjects will be assigned to one of two study groups to either be anesthetized with Bupivacaine or Lidocaine prior to needed treatment of pulpectomy/endodontic debridement on a…
- Trial name
- B-OHIP14 (NCT04787731)
- Testing
- Bupivacaine Local Anesthetic
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- NYU College of Dentistry
Multiple Sclerosis
Oral Carnosine for Neuromuscular Performance in Multiple Sclerosis
Low levels of tissue carnosine and mitochondrial dysfunction appears to accompany multiple sclerosis (MS), with oral carnosine might be applicable to tackle impaired bioenergetics and oxidative stress in MS, and perhaps win back…
- Trial name
- CARMUS (NCT03995810)
- Testing
- Carnosine, capsulle, 2 g/day, 8 weeks
- Where
- Serbia
- Volunteers
- 3 people
- Sponsor
- University of Novi Sad, Faculty of Sport and Physical Education
Partial Edentulism, Oral Health-Related Quality of Life
Oral Health Related Quality of Life in Cad Metallic and Poly Ether Ether Ketone (Peek) Partial Denture Frameworks in Mandibular Kennedy Class I Cases
The aim of this study was to compare CAD Poly ether ether ketone (PEEK) RPD to CAD metallic RPD in treating partial edentulism in terms of Oral health related quality of life
- Trial name
- NCT06789627
- Testing
- RPD with PEEK framework, RPD with metallic framework
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Osteoarthritis, Depression
Psychological, Sexually and Social Consequences of Osteoarthritis Treatment With THA or TKA and Joint Preserving Surgery
The project runs as a Ph.d. project at the Faculty of Health Sciences- University of Copenhagen. In Denmark the investigators operate around 16.000 artificial hips and knees yearly, mainly due to osteoarthritis.
- Conditions
- Osteoarthritis, Depression, Hip Dysplasia
- Trial name
- NCT01305759
- Where
- Denmark
- Volunteers
- 250 people
- Sponsor
- Hvidovre University Hospital
Oncology, Quality of Life
Measuring Health Related Quality of Life in AYAs
AIM1a: AYAs with cancer experience many challenges that impact their health-related quality of life (HRQOL) but few measures adequately capture AYAs' HRQOL in valid and reliable ways.
- Trial name
- PROMIS AYA (NCT03482778)
- Where
- 3 sites in United States
- Volunteers
- 165 people
- Sponsor
- Wake Forest University Health Sciences
NMDAR Antibody-associated Auto-immune Encephalitis
Psycho-social Impact of Anti-NMDAR Encephalitis
NMDA receptor encephalitis is a rare neurological autoimmune disease with severe neuropsychiatric symptoms, but a typically good functional neurological outcome.
- Trial name
- SAPIENCE (NCT05954468)
- Testing
- standardized and validated surveys
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Hospices Civils de Lyon
Oral Health-Related Quality of Life
Manus AI-Assisted Orthodontic Education and Oral Health-Related Quality of Life
The goal of this clinical trial is to learn whether adding artificial intelligence (AI)-assisted education to standard orthodontic education can improve quality of life in adults starting treatment with fixed braces.
- Trial name
- NCT07832604
- Testing
- Conventional Orthodontic Education, Manus AI-Assisted Orthodontic Education
- Volunteers
- 230 people
- Sponsor
- University of Malaya
Diabetes Mellitus, Type 2, Obesity
Lifestyle Intervention's Impact on Health Care Costs
The ICAN Pilot project aims to evaluate the differences in economic, clinical and quality of life outcomes of a nutrition intervention involving lifestyle case management and medical nutrition therapy by a registered dietitian…
- Trial name
- ICAN (NCT00717158)
- Testing
- Usual medical care, Lifestyle Case management
- Where
- United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Dentin Sensitivity
A Real-World Evidence Study Evaluating Oral Health Related Quality Of Life With Use Of A Stannous Fluoride Anti-Sensitivity Toothpaste For Dentin Hypersensitivity Management
This study will evaluate the impact of long-term use of a desensitizing toothpaste containing 0.454 percent (%) stannous fluoride (SnF2) on oral health related quality of life (OHrQoL) in a population of self-reported dentin…
- Trial name
- NCT06045026
- Testing
- Stannous fluoride
- Where
- United States
- Volunteers
- 536 people
- Sponsor
- HALEON
Urinary Bladder, Overactive
Study of VESIcare® In Overactive Bladder (OAB) Subjects to Evaluate Symptom Bother and Health Related Quality of Life
Evaluate the effect of VESIcare® on symptom bother for subjects with OAB
- Trial name
- VIBRANT (NCT00573508)
- Testing
- Solifenacin Succinate
- Where
- 59 sites in United States
- Volunteers
- 768 people
- Sponsor
- Astellas Pharma Inc
Quality of Life, Surgery
Quality of Life and High-Risk Abdominal Cancer Surgery
The investigators plan to measure the changes of health-related quality of life (HRQoL) at 6 months and 12 months after the following high-risk oncological abdominal surgery: gastrectomy, esophagectomy, pancreatectomy and…
- Conditions
- Quality of Life, Surgery, Cancer, Frailty
- Trial name
- ChangeQoL (NCT04444544)
- Testing
- High Risk Abdominal Surgery
- Where
- Switzerland
- Volunteers
- 295 people
- Sponsor
- University Hospital, Geneva
Prosthesis User
Patient Satisfaction and Oral Health-related Quality of Life (OHRQL) For Two Pick-up Techniques
This study aimed to evaluate patient satisfaction and OHRQL using two pick-up methods for locator retained mandibular overdenture
- Trial name
- NCT06109792
- Testing
- implant supported mandibular overdenture
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Healthy, Psychological Well Being
Survey of Psychological Well-being of Health Care Workers in the Hospital Setting
The psychological well-being of healthcare workers in hospital settings is a topic of growing interest in the scientific literature, given the crucial importance of their role in ensuring high-quality care.
- Conditions
- Healthy, Psychological Well Being, Stress Response, Professional Quality of Life
- Trial name
- IN-VISIBLE (NCT06923436)
- Testing
- Psychological Assessment
- Volunteers
- 500 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Obesity
Quality of Life Following Gastric Bypass Surgery.
A central goal of health care is to maximize patient functioning and well-being. This has prompted measurement of health-related quality of life (HRQOL) that encompasses physical, psychological, and social functioning.
- Trial name
- NCT02032199
- Where
- Denmark
- Volunteers
- 121 people
- Sponsor
- René Klinkby Støving
Stress, Anxiety
Medical Yoga for Patients With Stress-related Symptoms and Diagnoses
Background An increasing number of patients are suffering from stress-related symptoms and diseases. No scientific studies have examined the effects of Medical yoga on stress-related symptoms in patients in primary care.
- Conditions
- Stress, Anxiety, Depression
- Trial name
- NCT01604707
- Testing
- Medical Yoga
- Volunteers
- 44 people
- Sponsor
- Region Örebro County
Hearing Loss, Functional
Fitness, Hearing and Quality of Life in Older Adults With Hearing Loss. Walk, Talk and Listen for Your Life
This study examines the effect of an exercise and health education/auditory rehabilitation and socialization intervention on functional fitness, hearing handicap and psychosocial distress measures in older adults with hearing…
- Trial name
- WTL (NCT02662192)
- Testing
- Exercise + health education+ auditory rehabilitation, auditory rehabilitation alone
- Where
- Canada
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Multiple Sclerosis, Relapsing-Remitting
A Phase 4 Study to Assess the Impact of Patient Support Program on Health Related Quality of Life and Adherence in Subjects With Relapsing-Remitting Multiple Sclerosis Administered Rebif® With the RebiSmart™ Device
This is a randomized, comparative, and multicenter study to assess the impact of a patient support program (MinSupport Plus) on health related quality of life (HRQoL) and adherence in subjects with relapsing-remitting multiple…
- Trial name
- RebiQoL (NCT01791244)
- Testing
- Rebif®
- Where
- 14 sites in Germany, Sweden
- Volunteers
- 93 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Fibrotic Interstitial Lung Disease
Home-based Pulmonary Rehabilitation and Health Coaching in Fibrotic Interstitial Lung Disease
The purpose of this study is to gather information on the effectiveness of a home-based pulmonary rehabilitation program with health coaching and tele-monitoring for improving patient-reported respiratory-related quality of life…
- Trial name
- NCT05130034
- Testing
- Home-based pulmonary rehabilitation
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Mayo Clinic
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