Clinical trials: Health-related Quality of Life
Physical Activity
Smartphone Parent-child Partner Exercises Application Study
Building upon our previous groundwork including the development of the FAMILY MOVE app and the pilot study, we will further evaluate the effectiveness of a simple parent-child partner exercise programme delivered by our FAMILY…
- Trial name
- NCT03279354
- Testing
- Family Move app intervention, "HK FitNuts" app intervention
- Where
- Hong Kong
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Colorectal Neoplasms
Quality of Life of Patients With Colorectal Neoplasm and Cost-Effectiveness Analysis of Colorectal Cancer Screening
Introduction: Colorectal cancer (CRC) is the second most common cancer among Chinese in Hong Kong and the second leading cause of cancer death in this population.
- Trial name
- NCT02038283
- Where
- 3 sites in Hong Kong
- Volunteers
- 587 people
- Sponsor
- The University of Hong Kong
Freeman-Sheldon Syndrome, Arthrogryposis Distal Type 2A
Survey Study and Records Review of Treatment Outcomes in Freeman-Sheldon Syndrome
Freeman-Sheldon syndrome (FSS) is a rare muscle disorder present before birth, involving primarily problems of the face and skull and the hands and feet.
- Conditions
- Freeman-Sheldon Syndrome, Arthrogryposis Distal Type 2A, Whistling Face Syndrome, Craniocarpotarsal Dysplasia
- Trial name
- STOP-FSS (NCT01144741)
- Testing
- PTSD Checklist-Civilian (PCL-C), Modified Flanagan Quality of Life Scale, Center for Epidemiologic Studies Depression Scale (CES-D)
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Freeman-Sheldon Research Group, Inc.
Opioid Use Disorder, Opioid Withdrawal
Medically Supervised Ibogaine With 12-Month Digital Recovery Support for Opioid Use Disorder
IBO-CARE is a single-site Phase 1/2a study evaluating the safety, tolerability, feasibility and preliminary outcomes of medically supervised ibogaine with 12 months of recovery support in adults with moderate-to-severe opioid use…
- Conditions
- Opioid Use Disorder, Opioid Withdrawal, Substance Use Disorders
- Trial name
- IBO-CARE (NCT07871877)
- Testing
- Ibogaine Hydrochloride, Extended-release naltrexone injection, 380 mg, My-E-Health SENTINEL Digital Monitoring and Human-Gated Escalation Platform
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Clive Michelsen
Complete Edentulism
Clinical Performance and Quality of Life of 3D-Printed Complete Dentures Under Digital vs Hybrid Workflows: A Randomized Crossover Trial
This prospective randomized crossover clinical trial evaluates and compares the clinical performance and oral health-related quality of life (OHRQoL) of complete dentures fabricated through two additive manufacturing workflows …
- Trial name
- PRINT-DENT (NCT07626827)
- Testing
- Digital Workflow Complete Denture, Hybrid Workflow Complete Denture
- Where
- Ecuador
- Volunteers
- 20 people
- Sponsor
- Universidad de Especialidades Espiritu Santo
Pneumonia, Pulmonary Fibrosis
Pulmonary Rehabilitation in Non-chronic Obstructive Pulmonary Disease Patients.
To determine the effect of pulmonary rehabilitation on pulmonary function in non-chronic obstructive pulmonary disease patients.To determine the effect of pulmonary rehabilitation on health related quality of life in non-chronic…
- Conditions
- Pneumonia, Pulmonary Fibrosis, Tuberculosis, Bronchiectasis
- Trial name
- NCT05174741
- Testing
- Conventional Chest Physiotherapy, Aerobic training Group
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Domestic Violence, Intimate Partner Violence
The Relationship of Occupational Competence and Activity Role Participation to Life Satisfaction and Depression Severity in Women Exposed to Domestic Physical Violence at a Social Service Institution
The goal of this observational study is to examine the relationships between occupational competence, activity and role participation, life satisfaction, and depression severity in women aged 20-50 years who have experienced…
- Conditions
- Domestic Violence, Intimate Partner Violence, Depression, Activities of Daily Living
- Trial name
- NCT07454213
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Medipol University
Age-Related Osteoporosis
Dose-dependent Effects of Vitamin D on Bone Health
We propose to conduct a randomized double blind trial of three doses of vitamin D, 400, 4000, and 10,000 International Units (IU) per day, to assess the effect on bone density and architecture as assessed by high resolution…
- Trial name
- NCT01900860
- Testing
- Vitamin D
- Where
- Canada
- Volunteers
- 311 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Pulmonary Disease, Chronic Obstructive
Randomized Controlled Trial of Mind-Body Breathing Therapy (in Chronic Obstructive Pulmonary Disease) To Improve Palliation of Dyspnea and Health-Related Quality of Life
Dyspnea (shortness of breath) is a complex experience that includes interpretation of physical impairments and associated distress to the person.
- Trial name
- NCT00243282
- Testing
- Relaxation Response (instruction, pocket practice card prov), Mindfulness training using model developed from UMass
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- US Department of Veterans Affairs
Extracorporeal Membrane Oxygenation
Estimation of Outcome and Quality of Life in ECMO Patients
The availability as well as the use of extracorporeal membrane oxygenation (ECMO) systems for severe acute respiratory or cardiocirculatory failure is steadily increasing.
- Trial name
- ESTRELLA (NCT06400797)
- Testing
- estimation of patient outcome by health care providers
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Severe Hereditary Factor VIII Deficiency Disease Without Inhibitor, Moderate Hereditary Factor VIII Deficiency Disease Without Inhibitor
An Observational Study to Evaluate Physical Activity, Bleeding Incidence and Health Related Quality of Life, in Participants With Haemophilia A Without Inhibitors Receiving Standard of Care Treatment
This multicenter, non-interventional, prospective study will collect information about activity status, bleeds, health-related quality of life (HRQoL), health status, and safety in participants with moderate or severe haemophilia…
- Conditions
- Severe Hereditary Factor VIII Deficiency Disease Without Inhibitor, Moderate Hereditary Factor VIII Deficiency Disease Without Inhibitor, Haemophilia A
- Trial name
- POWER (NCT04165135)
- Testing
- Standard of Care for Haemophilia A
- Where
- 17 sites in Italy
- Volunteers
- 103 people
- Sponsor
- Hoffmann-La Roche
Juvenile Idiopathic Arthritis
OHRQoL Evaluation After Functional Therapy in JIA Patients
The aim of the study was to determine the changes in Oral Health-Related Quality of Life (OHRQoL) in patients with juvenile idiopathic arthritis (JIA) and temporomandibular joint (TMJ) disorders who underwent functional therapy…
- Trial name
- NCT03008681
- Testing
- Andresen functional removable orthodontic appliance
- Where
- Italy
- Volunteers
- 93 people
- Sponsor
- University of Messina
Dysmenorrhea
Survey on Menstrual Symptoms, Health Related Quality of Life and Work Productivity in Patients Suffering From Pain During Menstruation (Dysmenorrhea) in Japan
In this study researcher want to gain more information on the treatment effect of Low-dose Estrogen Progestin (a hormone treatment) on the health related quality of life and work productivity in patients suffering from menstrual…
- Trial name
- NCT04607382
- Testing
- LEP, NSAIDs and/or Chinese medicine (CM)
- Where
- Japan
- Volunteers
- 397 people
- Sponsor
- Bayer
Pre-frail Elderly
The Effect of SOD Enzyme on Frailty and HRQOL Among Indonesian Pre-frail Elderly: A Double Blind Randomized Controlled Trial
The primary objective is to determine the effect of SOD enzyme on frailty and health related quality of life among Indonesian pre-frail elderly.
- Trial name
- NCT02753582
- Testing
- SOD+Gliadin Capsule
- Where
- Indonesia
- Volunteers
- 150 people
- Sponsor
- Universitas Indonesia
Neuroendocrine Tumors, Quality of Life
HRQoL During PRRT in Patients With NETs
Neuroendocrine tumours (NETs) can arise in different locations in the body, and may give rise to hormonal symptoms, which may affect the patients' health-related quality of life (HRQoL).
- Conditions
- Neuroendocrine Tumors, Quality of Life, Peptide Receptor Radionuclide Therapy
- Trial name
- NCT05427032
- Volunteers
- 756 people
- Sponsor
- Uppsala University
Myofascial Pain Syndrome
Trial to Evaluate the Efficacy of Topical Capsaicin to Reduce Pain and Improve Health-related Quality of Life in Adults With Chronic Myofascial Neck Pain
Chronic neck pain is a common condition that can negatively impact quality of life. Substance P is one of the chemicals in the body that can transmit pain signals from overloaded neck muscles to the brain.
- Trial name
- NCT00795106
- Testing
- Capsaicin
- Where
- United States
- Sponsor
- Stamford Hospital
Dentin Hypersensitivity
A Study Evaluating Oral-Health-Related Quality of Life and Treatment Patterns Among Dentin Hypersensitivity Sufferers
The primary purpose of this study is to characterize changes in Oral-Health-Related Quality of Life (OHrQoL), as measured by the Dentin Hypersensitivity Experience Questionnaire (DHEQ) over a 12-month period.
- Trial name
- NCT07337109
- Where
- United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- HALEON
End Stage Renal Disease
The Benefit of Оn-Line High Convection Volume Hemodiafiltration Treatment Versus High Flow Dialysis on Reduction of Oxidative Stress and Health Related Quality of Life in Dialysis Patients
Introduction: Patients with end stage renal disease are exposed to metabolic and hemodynamic complications due to the disease itself and as a result of the dialysis treatment related complications.
- Trial name
- NCT02673099
- Testing
- HDF online
- Where
- Israel
- Volunteers
- 45 people
- Sponsor
- Western Galilee Hospital-Nahariya
Sarcoma
Assessing Health-related Quality of Life in Sarcoma Patients
Although the clinical effectiveness of sarcoma treatment has improved, long-lasting and cumulative treatment side-effects may often detract from the overall marginal advantage.
- Trial name
- NCT04071704
- Where
- 3 sites in Germany, Jordan
- Volunteers
- 654 people
- Sponsor
- The Netherlands Cancer Institute
Cervical Dysplasia
Sexual Function and Quality of Life After LEEP: a Prospective Multi-Center Study
The goal of this prospective study is to investigate the sexual function and quality of life of women undergoing loop electrosurgical excision procedure (LEEP) due to HPV-related cervical lesion.
- Trial name
- SEQUEL (NCT06078514)
- Testing
- Loop electrosurgical excision procedure (LEEP)
- Where
- 5 sites in Finland
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
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