Clinical trials: Health-related Quality of Life
Conservative Management, Diabetes Mellitus
Effects of Conservative Management on Relieving Storage Urinary Symptoms and Poor Sleep in Women With Diabetes
Women with type 2 diabetes (n=90) experiencing ≥1 storage lower urinary tract symptoms and poor sleep health will be recruited from the outpatient departments or wards/units of the selected hospitals/clinics.
- Conditions
- Conservative Management, Diabetes Mellitus, Health-related Quality of Life, Lower Urinary Tract Symptoms
- Trial name
- NCT05869734
- Testing
- Sleep health promotion, Urologic health promotion, Pelvic floor muscle training
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- National Yang Ming Chiao Tung University
Metastatic Colorectal Cancer (mCRC)
Randomized Controlled Trial of the Effects of Combined Resistance and AerobiC Exercise on Health-related Quality of Life in Patients Undergoing First-line Chemotherapy for Metastatic Colorectal Cancer (REACH)
The primary objective of this trial is to compare the effects of 18 weeks structured exercise training versus on control on healt-related quality of life in patients with mCRC undergoing first-line chemotherapy.
- Trial name
- REACH (NCT06938971)
- Testing
- Exercise training
- Where
- 4 sites in Denmark
- Volunteers
- 150 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Sexuality, Depression
Sexual Health Education During Pregnancy
This experimental, randomized controlled, single-blind study includes intervention and control groups. Pregnant women between 16 and 20 weeks of gestation who meet the inclusion criteria and agree to participate will be included…
- Conditions
- Sexuality, Depression, Pregnancy Related
- Trial name
- NCT07517549
- Testing
- sexuality health education group
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ordu University
Prostate Cancer
Impact of Yoga As Complementary Therapy in Patients Undergoing Radical Prostatectomy
The researchers hope to learn if yoga complementary therapy would improve health-related quality of life, recovery of urinary continence and erectile function in patients who underwent prostate cancer surgery (i.e.
- Trial name
- NCT02620033
- Testing
- Yoga therapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Head and Neck Cancer, Alcohol Use, Unspecified
Alcohol Cessation Among Head and Neck Cancer Survivors
Head-and-neck cancers (HNC) account for 4 percent of cancer diagnoses in the United States and for more than 66,000 annual cancer diagnoses.
- Trial name
- NCT05570851
- Testing
- Alcohol Cessation Text Messages, Usual Care
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Northwell Health
Cerebral Palsy
Effects of Lokomat-Robot Assisted Gait Training on Gross Motor Function in Children and Young Adults With Cerebral Palsy
This single-center, controlled, delayed-intervention, quasi-experimental study evaluates the effectiveness of Lokomat®-assisted robotic gait training on gross motor function and health-related quality of life in children and…
- Trial name
- NCT07732205
- Testing
- Sessions with Lokomat robot-assisted system, Control arm
- Where
- Hungary
- Volunteers
- 96 people
- Sponsor
- Semmelweis University
Bipolar Disorder (BD), Quality of Life (QOL)
Evaluating the PolarUs App in People With Bipolar Disorder
Our team recently pilot tested a new mobile app, PolarUs, co-designed with people who live with bipolar disorder (BD), to support BD self-management and quality of life (QoL) measurement.
- Trial name
- NCT07890805
- Testing
- PolarUs Mobile App
- Where
- Canada
- Volunteers
- 504 people
- Sponsor
- University of British Columbia
Multiple Sclerosis, Relapsing-Remitting
An Observational Study Comparing Multiple Sclerosis International Quality of Life Questionnaire (MusiQoL) and Multiple Sclerosis Quality of Life-54 Instrument (MSQOL-54) in Relapsing Multiple Sclerosis (RMS) Patients on Long-term Rebif® Therapy
Significant data from placebo-controlled clinical trials have demonstrated the efficacy of Rebif in relapsing remitting multiple sclerosis (RRMS) with reduction in relapse rate, delay in disability progression, and reduction in…
- Trial name
- COMPARE (NCT01141751)
- Volunteers
- 334 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Quality of Life
The Influence of Exercise on Mental Health After Discharge From Hospital
The aim of this study is to evaluate the effect of aerobic fitness training on mental health (health-related quality of life),cognitive and physical capacity in older people discharge from hospital and to assess if further…
- Trial name
- NCT01204567
- Testing
- Aerobic training
- Where
- Norway
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Prostatic Neoplasms, Exercise
Health Effects of Soccer Training in Men With Prostate Cancer Receiving Androgen Deprivation Therapy
Androgen Deprivation Therapy (ADT) is standard treatment for locally advanced or advanced Prostate Cancer (PC). The musculoskeletal toxicity associated with ADT is well established, leading to a decrease in muscle mass, increased…
- Conditions
- Prostatic Neoplasms, Exercise, Soccer Training, Androgen Deprivation Therapy
- Trial name
- NCT01711892
- Testing
- Soccer training
- Where
- Denmark
- Volunteers
- 57 people
- Sponsor
- University of Copenhagen
Chronic Obstructive Pulmonary Disease
A 12 Week Physical Training Programme for Patients With Chronic Obstructive Pulmonary Disease
The purpose of this study is to determine whether water based or land based group training is more effective for people with COPD.
- Trial name
- NCT00744484
- Testing
- Training in water, Training on land
- Where
- Norway
- Volunteers
- 22 people
- Sponsor
- Norwegian University of Science and Technology
Stroke, Post-Stroke Spasticity
Effect of Extracorporeal Shock Wave Therapy on Spasticity and Mobility in Stroke Patients
This study aims to evaluate the effectiveness of extracorporeal shock wave therapy (ESWT) in individuals with lower limb spasticity following stroke.
- Conditions
- Stroke, Post-Stroke Spasticity, Lower Limb Spasticity
- Trial name
- ESWT-STROKE (NCT07523243)
- Testing
- Extracorporeal Shock Wave Therapy (ESWT)
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Istanbul Medipol University Hospital
Hepatitis C, Chronic, Genotype 1
Quality of Life During Treatment of Chronic Hepatitis C (P05278/MK-4031-336)
The primary objective of this study is to evaluate the impact of chronic hepatitis C (CHC), and the treatment thereof with peginterferon alpha-2b (PEG) and ribavirin (RBV) according to standard clinical practice, on the…
- Conditions
- Hepatitis C, Chronic, Genotype 1, HCV-1
- Trial name
- VIDA (NCT00863109)
- Testing
- Peginterferon alfa-2b (PEG), Ribavirin (RBV)
- Volunteers
- 133 people
- Sponsor
- Merck Sharp & Dohme LLC
Recipients of Liver Transplant
Envarsus XL Immunosuppression Following Liver Transplantation
The standard immunosuppressive regimen for liver transplantation includes twice daily tacrolimus (Prograf). In other transplantation models, there are potential benefits to extended release formulations as lower peak…
- Trial name
- NCT03828058
- Testing
- Envarsus XR, Prograf
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Methodist Healthcare - Memphis
Veno-arterial Extra-Corporeal Membrane Oxygenation, Health Related Quality of Life
Health-related Quality of Life in Adults After Veno-arterial Extra-Corporeal Membrane Oxygenation Which is a Salvage Therapy Used in Patients With Severe Respiratory or Cardiac Failure Who Have Not Responded to Maximal Conventional Medical Therapy
Extracorporeal Membrane Oxygenation (ECMO) is a salvage therapy used in patients with refractory cardiogenic shock. This rescue technique is associated to a high mortality rate and to many complications that can impact the…
- Trial name
- NCT04653298
- Testing
- Evaluation of quality of life, comorbidities and return to work status
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Strasbourg, France
COPD, Obesity
Effects of Obesity on COPD
The purpose of this study is to investigate whether obese COPD patients experience more or less discomfort in daily life. Furthermore the investigators will evaluate if body composition or body fat distribution has effects on…
- Conditions
- COPD, Obesity, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT06474858
- Where
- Netherlands
- Volunteers
- 166 people
- Sponsor
- Rijnstate Hospital
Scleroderma, Systemic
Health-related Quality of Life in Korean Patients With Rheumatic Diseases
To compare the health related quality of life of patients with systemic sclerosis with other rheumatic diseases, such as rheumatoid arthritis, systemic lupus erythematosus and Sjogren's syndrome.
- Trial name
- NCT03257878
- Testing
- validated Korean version of the SF36 and EQ-5D
- Where
- South Korea
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Esophageal Achalasia
Quality of Life After POEM for Achalasia
Achalasia is an esophageal motility disorder, characterized by insufficient lower esophageal sphincter relaxation and loss of esophageal peristalsis.
- Trial name
- NCT05010889
- Testing
- Peroral endoscopic myotomy (POEM)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Multiple Myeloma, Hematologic Diseases
Observational Study of Home Administration of Carfilzomib
The purpose of this study is to evaluate the feasibility of an at home administration program for carfilzomib patients.
- Trial name
- KARE-2 (NCT04621955)
- Where
- 5 sites in Belgium
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Quality of Life
Identifying Predictors of Poor Health-Related Quality-of-Life Among Pediatric Hematopoietic Stem Cell Donors
To compare donors to their non-donor counterparts and healthy controls as well as to generate trajectory classes based on longitudinal patterns of donor HRQoL and identify predictors of poor donor HRQoL.
- Trial name
- NCT03718546
- Where
- 31 sites in United States
- Volunteers
- 754 people, healthy volunteers welcome
- Sponsor
- Center for International Blood and Marrow Transplant Research
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