Clinical trials: Health-related Quality of Life
Cancer Patients
A Patient Consensus for the Research in Supportive Care in French Cancer Care Centers: the CyPRES Project
In oncology a number of supportive care therapies are proposed to patients. This study will identify the different therapies and prioritize these therapies from the patients' perspectives.
- Trial name
- CyPRES (NCT03320161)
- Where
- 58 sites in France, Martinique
- Volunteers
- 604 people
- Sponsor
- UNICANCER
Breast Cancer, Hormone Dependent Neoplasms
A Web-Based Tool to Improve Breast Cancer Survivorship
The purpose of this study is to examine the efficacy of a psychosocial eHealth intervention on the proposed primary outcomes, hormone therapy adherence and health related quality of life (HRQoL), in breast cancer survivors.
- Conditions
- Breast Cancer, Hormone Dependent Neoplasms, Adherence to Hormone Therapy
- Trial name
- NCT03849573
- Testing
- "OncoTool" Intervention (MBSR + HT education), "Oncotool" Control (health +HT education)
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Northwestern University
Small Cell Lung Cancer, Extensive-Stage Small Cell Lung Cancer
MDT-Based Nursing for Small Cell Lung Cancer During Chemo-Immunotherapy
This study aims to develop and evaluate a multidisciplinary team (MDT)-based nursing intervention system for patients with advanced small cell lung cancer (SCLC) receiving chemo-immunotherapy.
- Conditions
- Small Cell Lung Cancer, Extensive-Stage Small Cell Lung Cancer, Lung Neoplasms
- Trial name
- SCLC-MDT (NCT07489339)
- Testing
- Multidisciplinary Team-Based Nursing Intervention, Routine Nursing Care
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanxi Province Cancer Hospital
Ischemic Heart Disease
Ozone Therapy in Refractory Ischemic Heart Disease.
The main objective of this clinical trial is to evaluate the effectiveness and cost-effectiveness of adding ozone therapy to standard management of patients with advanced ischemic heart disease refractory to medical and surgical…
- Trial name
- O3Cardio (NCT03660657)
- Testing
- Ozone, Oxygen
- Where
- Spain
- Volunteers
- 1 people
- Sponsor
- Bernardino Clavo, MD, PhD
Catheter Related Complications
Central Catheters Used for Chemotherapy in Women With Breast Cancer
The overall aim of this study is to evaluate two different central venous lines, PICC-lines (PICC) and subcutaneous venous access ports (SVAP) used for chemotherapy in women with breast cancer.
- Trial name
- PICC&PAC (NCT04324346)
- Testing
- FEC75 (or EC90) x 6, FEC100 + Taxotere (EC90 + Taxotere) 3+3, Paclitaxel
- Where
- Sweden
- Volunteers
- 250 people
- Sponsor
- Swedish Red Cross University College
Multimorbidity
Telehealth-delivered Peer Support to Improve Quality of Life Among Veterans With Multimorbidity
The VetASSIST study is a randomized clinical trial testing whether receiving virtual health coaching from Veteran peers improves the physical and mental health-related quality of life of Veterans with multiple chronic health…
- Trial name
- VetASSIST (NCT05560451)
- Testing
- Peer health coach intervention
- Where
- United States
- Volunteers
- 298 people
- Sponsor
- VA Office of Research and Development
Subclinical Spinal Pain
The Effects of Chiropractic Care in Adults With Subclinical Spinal Pain
This study aims to investigate long term and retention (in a subgroup) effects of Chiropractic care (CC) on neurological, behavioral, immunological functions and health-related quality of life in adults with subclinical pain.
- Trial name
- NCT05369156
- Testing
- Chiropractic Care, Control Group
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Riphah International University
Gastrointenstinal Stromal Tumor (GIST)
Long-term Survivorship Challenges of Advanced/Metastatic GIST Patients Responding to Tyrosine Kinase Inhibitor Treatment: an Observational Study
Gastrointestinal stromal tumours (GISTs) are rare malignancies arising along the gastrointestinal tract. Tyrosine kinase inhibitors (TKIs) have substantially improved survival for patients with unresectable or metastatic GIST.
- Trial name
- NCT07522762
- Where
- Netherlands
- Volunteers
- 330 people
- Sponsor
- The Netherlands Cancer Institute
Low Vision, One Eye, Unspecified Eye, Low Vision Blindness
Health Education vs Meditation in Irreversible Age-Related Vision Loss Patients and Their Caregivers
Investigators aim to assess the feasibility of delivering two augmentation interventions, Meditation and a Health Enhancement Program, for potentially enhancing the quality of life and mental health of Irreversible Age-Related…
- Trial name
- NCT03166072
- Testing
- Meditation, Health Enhancement Program
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Health Behavior, Health-Related Behavior
Preventive Remediation for OptiMal StudentS (PROMESS-Group)
Health students exhibit excessive sedentary behavior, elevated stress levels, and significant sleep disturbances, all of which contribute to a decline in their overall health, quality of life, and learning capacities.
- Trial name
- PROMESS-Group (NCT07030751)
- Testing
- Stress management, sleep improvement and fatigue reduction, sedentary behaviors reduction and physical activity promotion.
- Where
- France
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Research on Healthcare Performance Lab U1290
Thyroid Disease, Hashimoto's Thyroiditis
ThyMoves: Screening and Exercise to Improve Muscle, Enhance Quality of Life, and Reduce Fall Risk in Thyroid Disease
Objectives: This study aims to assess health-related quality of life (QoL) in adults with thyroid hormone disorders and identify modifiable factors to improve QoL in patients with Hashimoto's thyroiditis (HT) and multinodular…
- Conditions
- Thyroid Disease, Hashimoto's Thyroiditis, Hyperthyreosis and Goiter, Hypothyroidism
- Trial name
- ThyMoves (NCT06960005)
- Testing
- Rhythm- and Multitask-Based Activity (RYMA) and Activities of Daily Living (ADL)
- Where
- Denmark
- Volunteers
- 148 people
- Sponsor
- Aalborg University Hospital
Other Disorders of Glucose Regulation and Pancreatic Internal Secretion, Pancreatic Cancer
PancFit: Multimodal Exercise During Preoperative Therapy for Pancreatic Cancer
Any time the words "you," "your," "I," or "me" appear, it is meant to apply to the potential participant. The goal of this clinical research study is to learn if regular exercise and behavioral skills training can help to improve…
- Trial name
- NCT03187951
- Testing
- Questionnaires, Nutritional Questionnaire and Nutritional Counseling, Booklet
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- M.D. Anderson Cancer Center
Obesity and Obesity-related Medical Conditions
"F!reF!ghterF!t": Lifestyle Coaching Interventions for Obese Firefighters (FireFit)
Our goal is to explore the effectiveness of 9- month lifestyle medicine based coaching intervention (individual and group coaching) versus control (usual care/ written health instructions).
- Trial name
- FireFit (NCT06890975)
- Testing
- Lifestyle Coaching
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Cambridge Health Alliance
Stroke, Quality of Life
Measuring Health Related Quality of Life in Veterans With Stroke
Approximately 11,000 veterans annually are hospitalized with a newly acquired incident stroke. Based on American Heart Association ratios of stroke incidence and prevalence, up to 80,000 veterans may be stroke survivors.
- Conditions
- Stroke, Quality of Life, Rehabilitation
- Trial name
- NCT00123357
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- US Department of Veterans Affairs
Vision; Disorder, Loss, Caregiver Burnout
Virtual Health Education vs Meditation in Irreversible Age-Related Vision Loss Patients and Their Caregivers
Vision loss is common among older adults and leads to an increased risk for depression and difficulties in daily tasks, thus requiring dependence on caregivers.
- Conditions
- Vision; Disorder, Loss, Caregiver Burnout, Quality of Life, Depression
- Trial name
- NCT04583748
- Testing
- Sahaj Samadhi Meditation, Health Enhancement Program
- Volunteers
- healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Heart Transplant Patients, Kidney Transplant Patients
Multidisciplinary Non-Pharmacological Intervention to Improve Quality of Life in Solid Organ Transplant Recipients
This is a single-center interventional study aimed at evaluating the feasibility of a multidisciplinary non-pharmacological approach based on acupuncture, telerehabilitation-based physical rehabilitation, and brain health…
- Conditions
- Heart Transplant Patients, Kidney Transplant Patients, Lung Transplant, Liver Transplanted Patients
- Trial name
- TAO (NCT07870811)
- Testing
- Acupuncture, Telerehabilitation-Based Physical Rehabilitation, Psychological Support Program
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- The Mediterranean Institute for Transplantation and Advanced Specialized Therapies
Edentulous Jaw, Quality of Life
Impact of the Use of New Complete Denture on the Oral Health Related to Quality of Life (OHRQoL)
The aim of this project was to evaluate the impact before and after (3, 6, 9, and 12 months) of oral rehabilitation with conventionalof the insertion of new complete dentures (CD) in the oral health-related quality of life…
- Trial name
- NCT03687047
- Testing
- New complete dentures
- Where
- Brazil
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Post Traumatic Stress Disorder PTSD, Quality of Life
Effectiveness of Trauma Treatment in the Specialist Health Care Services
Post-traumatic stress disorder (PTSD) is a common mental illness. Treatments for PTSD are regarded as highly effective, but a large-scale, prospective, longitudinal randomized controlled trial comparing the effectiveness of these…
- Conditions
- Post Traumatic Stress Disorder PTSD, Quality of Life, Functional Outcome, Complex Post-Traumatic Stress Disorder
- Trial name
- NCT06691347
- Testing
- Eye movement desensitization and reprocessing, Cognitive therapy for PTSD
- Where
- Norway
- Volunteers
- 270 people
- Sponsor
- Vestre Viken Hospital Trust
Aortic Valve Stenosis, Limited Access Aortic Valve Replacement
Patient Reported Health-Related Quality of Life After Limited Access and Conventional Aortic Valve Replacement
The LIAR-Trial is a single-center, single blind randomized controlled clinical trial comparing patients undergoing isolated AVR via J-shaped upper hemi-sternotomy (UHS) and conventional AVR through a full median sternotomy (FMS).
- Conditions
- Aortic Valve Stenosis, Limited Access Aortic Valve Replacement, Quality of Life
- Trial name
- LIAR (NCT04012060)
- Testing
- Limited access aortic valve replacement., Conventional aortic valve replacement
- Where
- Netherlands
- Volunteers
- 161 people
- Sponsor
- St. Antonius Hospital
Anxiety and Fear
Memory and Fear Study (Fear of Memory Loss Study)
This study is a randomized control study to determine the impact of a tailored, web-based mindfulness program to reduce anxiety and increase the quality of life in older adults experiencing dementia-related fears, relative to a…
- Trial name
- NCT04821960
- Testing
- Tailored Mindfulness Program for Fear of Memory Loss, Conventional Mindfulness Program
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Northwestern University