Clinical trials: Health-related Quality of Life
Missing Teeth, Partial Edentulism
OHQoL With Removable Partial Dentures; a Pilot Study
Removable false teeth (called removable partial dentures (RPDs)) are commonly made for people with missing teeth. RPDs are made out of a framework and the replacement teeth/gum.
- Trial name
- NCT01953991
- Testing
- Dentures
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Health Related Quality of Life
Health Related Quality of Life Assessment In Egyptian Recipients After Living Donor Liver Transplantation
Health Related Quality of Life Assessment In Egyptian Recipients After Living Donor Liver Transplantation
- Trial name
- NCT01784497
- Where
- Egypt
- Volunteers
- 35 people
- Sponsor
- Ain Shams University
Breast Cancer Female, Survivorship
Nurse-led Physical Activity Program Among Breast Cancer Survivors
A nurse-led physical activity program including an individualized exercise program using wearable technology and health coaching based on Social Cognitive Theory will be implemented for women surviving cancer.
- Conditions
- Breast Cancer Female, Survivorship, Health Behavior
- Trial name
- WATSOCPAP (NCT06248918)
- Testing
- WATSOCPAP
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Femoroacetabular Impingement Syndrome
First-line Treatment for Femoroacetabular Impingement Syndrome
There is sparse evidence on the effectiveness of first-line treatment in patients with femoroacetabular impingement syndrome (FAIS) regarding clinical- and cost-effectiveness.
- Trial name
- BetterHip (NCT05927935)
- Testing
- Supervised strength exercise intervention, Minimal educational intervention (usual care)
- Where
- 5 sites in Australia, Denmark
- Volunteers
- 120 people
- Sponsor
- University of Aarhus
Endometriosis, Endometriosis Related Pain
Efficacy of Physical Therapy Treatment in Endometriosis and Its Relationship to Adherence Rates.
The main objective of this study is to know if the application of both therapies, neuroscience pain education plus therapeutic exercise will modify pain, catastrophizing and quality of life in endometriosis.
- Conditions
- Endometriosis, Endometriosis Related Pain, Endometriosis, Pain, Endometriosis-related Pain
- Trial name
- NCT06795243
- Testing
- PAIN NEUROSCIENCE EDUCATION AND THERAPEUTIC EXERCISE PROGRAM, USUAL CARE
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- University of Seville
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health
Ambient air temperatures in Asian, Latin American, African, and Pacific climate hotspots have broken record highs in 2024, driven by man-made climate change. Solutions are needed to reduce heat exposure in communities.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- REFLECT (NCT06579950)
- Testing
- Cool roof
- Where
- 5 sites in Burkina Faso, Fiji and 3 more
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Parkinson Disease (PD), Parkinson's Disease
Real-world Patient Experiences With Inbrija®
Parkinson's disease can cause OFF episodes, when medication effects wear off and symptoms return, affecting movement, daily activities, comfort, and wellbeing.
- Conditions
- Parkinson Disease (PD), Parkinson's Disease, Off Episodes of Parkinson Disease
- Trial name
- INHALE-PD (NCT07797790)
- Testing
- Levodopa inhalation powder
- Where
- 2 sites in Austria
- Volunteers
- 120 people
- Sponsor
- Merz Therapeutics GmbH
Atrial Fibrillation (AF), Atrial Fibrillation Ablation
Catheter Ablation vs Conservative Care in Elderly Patients With Atrial Fibrillation
ACE-AF is a multicenter randomized study in people aged 78 years and older with symptomatic atrial fibrillation (AF). AF is a common heart rhythm disorder in older adults and can cause reduced quality of life and lead to serious…
- Conditions
- Atrial Fibrillation (AF), Atrial Fibrillation Ablation, Elderly
- Trial name
- ACE-AF (NCT07424690)
- Testing
- Catheter Ablation for Atrial Fibrillation, Optimized Medical Therapy for Atrial Fibrillation, Implantable Loop Recorder (ILR)
- Where
- 2 sites in Sweden
- Volunteers
- 282 people
- Sponsor
- Karolinska University Hospital
Vulvar Atrophy, Vulvovaginal Signs and Symptoms
Changes in the Impact of Genitourinary Syndrome of Menopause With a Novel Nonhormonal Vulvovaginal Gel Assessed by PROMs.
The goal of this clinical trial is to improve the management of Genitourinary syndrome of menopause (GSM) to preliminary assess safety and effectivity of a novel hormone-free mucosa composition (XCMIM20m) applied topically to the…
- Conditions
- Vulvar Atrophy, Vulvovaginal Signs and Symptoms, Genitourinary Syndrome of Menopause, Quality of Life
- Trial name
- STOPGSMP (NCT06962345)
- Testing
- Hormone-free vulvovaginal gel with the tested composition XCMIM20m
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Mucosa Innovations, S.L.
Dentin Hypersensitivity, Quality of Life
Validation of a French Version of the DHEQ
Dentin hypersensitivity (DH) results in brief, sharp pain in response to a stimulus. It often seems to be underdiagnosed but also undertreated due to the lack of consensus on the topic.
- Trial name
- DHEQ-VALID (NCT06466200)
- Testing
- Schiff Test, GOHAI questionnaire, OHIP questionnaire
- Where
- 3 sites in France
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Moderate to Severe Chronic Plaque Psoriasis
Post Marketing Observational Study on Venezuelan Patients With Psoriasis
The aim of this study is to obtain Venezuelan data of clinical effectiveness, impact in the HRQoL, work productivity and activity impairment in patients with psoriasis using adalimumab.
- Trial name
- NCT01758705
- Sponsor
- AbbVie (prior sponsor, Abbott)
Partial Edentulism Class 3
Compare CAD/CAM Metallic RPD to Conventional Metallic RPD in Terms of Oral Health Related Quality of Life
Patients will be randomised to receive CAD/CAM metallic removable partial denture (RPD) followed by Conventional metallic RPD (Group A), or the opposite sequence (Group B), with a 3-month wear duration for each denture and…
- Trial name
- NCT06567262
- Testing
- CAD/CAM metallic removable partial denture, Conventional metallic removable partial denture
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Cairo University
Patient Satisfaction
Polyetherketoneketone and Metal Framework for Management of Maxillectomy Cases: Across Over Study
Prosthetic rehabilitation of acquired maxillary defects represents a challenging mission for both the prosthodontist and psychologically traumatized patients.
- Trial name
- NCT06070727
- Testing
- Obturator
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Lower Respiratory Tract Infection (LRTI), Chest Infection
Quality of Life After Lower Respiratory Tract Infection
Lower respiratory tract infections (LRTIs) are any infections below the vocal cords which affect the airways or the air sacs in the lungs.
- Conditions
- Lower Respiratory Tract Infection (LRTI), Chest Infection, Quality of Life
- Trial name
- NCT07807917
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- University of Nottingham
Multiple Myeloma
A Study of Health-Related Quality of Life in People With Multiple Myeloma Receiving Daratumumab or Lenalidomide
The purpose of this study is to compare maintenance therapy approaches in people with newly diagnosed multiple myeloma (MM) that has responded well to a first round of treatment.
- Trial name
- NCT04497961
- Testing
- Lenalidomide, Daratumumab, Questionnaires
- Where
- 7 sites in United States
- Volunteers
- 95 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Multiple Myeloma
A Study Assessing the Health-Related Quality of Life (HRQoL) in Participants With Relapsed and/or Refractory Multiple Myeloma (RRMM) With Triple Class Exposure
The purpose of this observational study is to assess HRQoL in relapsed and/or refractory multiple myeloma (RRMM) participants who have previously received a proteasome inhibitor, an immunomodulatory agent, and an anti-CD38…
- Trial name
- NCT05217082
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Bristol-Myers Squibb
Peri Implantitis
Quality of Life and Related Factors in People With Peri-Implantitis
This single-center cross-sectional observational study evaluated oral health-related quality of life and its relationship with patient- and implant-level characteristics in adults with peri-implantitis.
- Trial name
- NCT07761403
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Suleyman Demirel University
Quality of Life, Family Relations
Family to Family: Psychoeducation to Improve Children's Outcomes in HIV+ Families
This project aims to support adults in HIV-affected families in order to improve their well-being. UCLA's Center for Community Health (CCH), in collaboration with the Thai Ministry of Public Health, Bureau of Epidemiology, will…
- Conditions
- Quality of Life, Family Relations, Mental Health, Physical Health
- Trial name
- NCT01037946
- Testing
- Cognitive behavioral sessions
- Where
- United States
- Volunteers
- 1,033 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
ARDS, COVID-19 Pneumonia
HRQOL of Life After ECMO Due to COVID-19.
We intend to prospectively investigate physical and mental state (HRQOL) by means of quantitative telephone interviews after hospital discharge in patients surviving COVID-19 ARDS and ECMO therapy.
- Conditions
- ARDS, COVID-19 Pneumonia, Extracorporeal Membrane Oxygenation
- Trial name
- NCT05531032
- Testing
- Phone Interview
- Where
- Austria
- Volunteers
- 44 people
- Sponsor
- Medical University of Vienna
Liver Transplantation
Measurement of Gastrointestinal (GI) and Health-related Quality of Life (HRQL) Outcomes in Liver Transplant Recipients
Treatment with the immunosuppressive drug mycophenolate mofetil (MMF) may result in gastrointestinal (GI) complications in some patients.
- Trial name
- NCT00405652
- Testing
- Enteric-coated Mycophenolate sodium (EC-MPS)
- Where
- Germany
- Volunteers
- 34 people
- Sponsor
- Novartis Pharmaceuticals
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