Clinical trials: Health-related Quality of Life
Amputees
Traumatic Below-knee Amputees With Prosthetics: Health-related Quality of Life and Locomotor Capabilities
The present study assesses the health-related quality of life and the locomotor capabilities major traumatic lower limb amputees who use prosthesis.
- Trial name
- NCT02439463
- Testing
- Below-knee amputation
- Where
- Finland
- Volunteers
- 26 people
- Sponsor
- Helsinki University Central Hospital
Total Hip Replacement
Randomized Clinical Trial of Ceramic Bearing Primary Total Hip Arthroplasty
Primary total hip arthroplasty (THA) has been a very successful surgical intervention in the geriatric population. Numerous studies have reported good mid and long term results of THA in patients over the age of 60 years.
- Trial name
- NCT01522014
- Testing
- Secure-Fit™ arc-deposited Hydroxylapatite (HA) shell - surface ceramic and an Alumina Bearing Couple (ABC) ceramic insert and Ceramic C-taper head, Secure-Fit™ arc-deposited hydroxylapatite shell, a Crossfire® insert and a Ceramic C-taper head
- Where
- 2 sites in Canada
- Volunteers
- 92 people
- Sponsor
- University of Alberta
Venous Thromboembolism (VTE), Exercise Therapy
Early Exercise-Based Rehabilitation in Patients Hospitalized for Acute Pulmonary Embolism
Up to half of patients with pulmonary embolism (PE) suffer from impaired quality of life, reduced physical capacity, and symptoms like shortness of breath even three months after diagnosis, despite standard treatment with…
- Conditions
- Venous Thromboembolism (VTE), Exercise Therapy, Quality of Life (QOL), Anxiety Depression
- Trial name
- RehabPE (NCT07143539)
- Testing
- Exercise-based rehabilitation program
- Where
- 6 sites in Switzerland
- Volunteers
- 160 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Perimenopause, Postmenopause
Effects of a Dietary Supplement in Women With Late Perimenopause or Early Postmenopause
This study will evaluate the effects of a plant extract-based dietary supplement on menopausal symptoms and health indicators in women with late perimenopause or early postmenopause.
- Conditions
- Perimenopause, Postmenopause, Hot Flashes
- Trial name
- NCT07863973
- Testing
- Plant Extract-Based Dietary Supplement
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Alicante
Quality of Life
Yoga in Adult Cancer: A Feasibility Trial
A feasibility study to determine the appropriateness of yoga intervention to improve health-related quality of life in adult cancer patients.
- Trial name
- Y-ACT (NCT02309112)
- Testing
- Yoga
- Volunteers
- 15 people
- Sponsor
- University of Oxford
Cognitive Remediation, Neuropsychology
Longitudinal Neurocognitive, Psychosocial and Health-related Quality of Life Assessment in Advanced Cancer Survivors Treated With Immunotherapy and the Efficacy of Integrative Neurocognitive Remediation Therapy
Since 2010, the field of immunotherapy has grown substantially, leading to a growing population of long-term cancer survivors treated with immunotherapy.
- Conditions
- Cognitive Remediation, Neuropsychology, Quality of Life, Psycho-Oncology
- Trial name
- CognIT (NCT05667857)
- Testing
- Integrative neurocognitive remediation therapy
- Where
- 2 sites in Belgium
- Volunteers
- 100 people
- Sponsor
- Universitair Ziekenhuis Brussel
Esophagogastric Junction Distensibility, Hiatal Hernia
Esophagogastric Junction Distensibility During Hiatal Hernia Repair
The investigators aim to ascertain the effects of hiatal hernia repair and fundoplication on the distensibility of the esophagogastric junction (EGJ) as measured by FLIP topography/impedance planimetry.
- Trial name
- NCT04450628
- Testing
- EndoFLIP
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Wake Forest University Health Sciences
Oral Habits
A Clinical Comparative Study of Different Methods for Correcting Lower Lip Sucking Habits in Preschool Children
Comparison of the Effectiveness of Behavioral Therapy, Maxillary Lip Bumper Appliance, and Twin-Block Appliance in Correcting Lower Lip Sucking Habits in Children
- Trial name
- NCT06650241
- Testing
- Behavioral therapy, Lip Bumper Therapy, Modified Twin-Block Therapy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Qingdao University
Low Back Pain
The Effect of Graded Activity and Pain Education (GAPE) for Patients Early After Lumbar Spinal Fusion
Background An increasing number of patients with chronic low back pain (CLBP) undergo lumbar spinal fusion (LSF). Unfortunately, a substantial part of the patients still has persistent pain, functional disability and poor quality…
- Trial name
- NCT04103970
- Testing
- Graded Activity and Pain Education (GAPE)
- Where
- Denmark
- Volunteers
- 144 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Aging, Aging Well
100-Year Human Aging Study
The 100-Year Human Aging Study is a prospective, pragmatic, observational trial enrolling participants across fixed clinical sites, mobile clinical sites, and an online participation pathway (current and future) to undergo…
- Conditions
- Aging, Aging Well, All-Cause Mortality, Mortality
- Trial name
- NCT07563777
- Testing
- Comprehensive Multi-System Clinical Screening
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.
Rheumatoid Arthritis
Cost Utility Analyses of Adalimumab Treatment in Patients With Rheumatoid Arthritis (RA)
Evaluation of Health Related Quality of Life (HRQL) is of a paramount importance in assessing the impact of rheumatoid arthritis on patients' health status, however when costs associated with rheumatoid arthritis are also taken…
- Trial name
- HEOR (NCT01078116)
- Where
- 10 sites in Greece
- Volunteers
- 124 people
- Sponsor
- Abbott
Diabetes; Neuropathy, Polyneuropathy (Manifestation)
FOot CAre and Exercises ImplementatioN for People With Diabetes in Primary Care
The main objective of this type 2 hybrid implementation effectiveness trial is to implement a contextually appropriate preventive intervention for 12 weeks face to face group foot and ankle exercises for people with diabetic foot…
- Trial name
- FOCAIN (NCT05639478)
- Testing
- Foot-related exercises
- Where
- Brazil
- Volunteers
- 356 people
- Sponsor
- University of Sao Paulo General Hospital
Stroke
Quantifying Digital Behavior on Smart Phones - Data From Stroke Survivors
In this study, we want to continuously record the interaction of 50 stroke survivors with their smartphones during the first 3 months after discharge.
- Trial name
- QuantStroke (NCT04405635)
- Testing
- No intervention or exposure
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University of Aarhus
Chronic Inflammation, Chronic Pain
Gulf War Illness Inflammation Reduction Trial
The primary objective of this clinical trial is to determine if treatment with an anti-inflammatory drug (delayed-release prednisone) improves the health-related quality of life (HRQOL) of veterans with Gulf War Illness (GWI).
- Conditions
- Chronic Inflammation, Chronic Pain, Fatigue, Cognitive Impairment
- Trial name
- GWIIRT (NCT02506192)
- Testing
- Modified-Release Prednisone
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Minneapolis Veterans Affairs Medical Center
Pompe Disease
Development of an Assessment Tool for Health-related Quality of Life in Children and Adolescents With Pompe Disease
Health related quality of life (HrQoL), is "the patient's subjective perception of the impact of his disease and its treatment on his daily life, physical, psychological and social functioning and well-being" and thus constitutes…
- Trial name
- Pompe_HrQol (NCT04724213)
- Testing
- Testing of reliability / validity of new questionnaire
- Where
- Switzerland
- Volunteers
- 101 people
- Sponsor
- University Children's Hospital, Zurich
Liver Transplantation
Measurement of Gastrointestinal (GI) and Health-related Quality of Life (HRQL) Outcomes in Liver Transplant Recipients
Treatment with the immunosuppressive drug mycophenolate mofetil (MMF) may result in gastrointestinal (GI) complications in some patients.
- Trial name
- NCT00405652
- Testing
- Enteric-coated Mycophenolate sodium (EC-MPS)
- Where
- Germany
- Volunteers
- 34 people
- Sponsor
- Novartis Pharmaceuticals
Multiple Sclerosis
The Effect Of Proprioceptive Neuromuscular Facilitation Techniqueson in Patients With Multiple Sclerosis
The aim of this study is to examine the effects of PNF techniques on pain, motor function, fatigue and quality of life.
- Trial name
- NCT06102148
- Testing
- PNF Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Nilay Comuk Balci
Quality of Life
Effect of Colon Delivered Vitamin B2 on Gut Microbiota and Related Health Biomarkers in Healthy Older Adults
The goal of this intervention study (clinical trial) is to investigate the effect of colon-delivered Riboflavin (vitamin B2) on the faecal microbial composition and diversity in older healthy subjects (50 -70 years of age)
- Trial name
- NCT05803811
- Testing
- Riboflavin
- Where
- Ireland
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- dsm-firmenich Switzerland AG
Fibrotic Interstitial Lung Disease
Home-based Pulmonary Rehabilitation and Health Coaching in Fibrotic Interstitial Lung Disease
The purpose of this study is to gather information on the effectiveness of a home-based pulmonary rehabilitation program with health coaching and tele-monitoring for improving patient-reported respiratory-related quality of life…
- Trial name
- NCT05130034
- Testing
- Home-based pulmonary rehabilitation
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Mayo Clinic
Head and Neck Neoplasms, Dental Prosthesis
Impact of Fixed Dentures in Head and Neck Cancer (IMFDHAC)
The purpose of the multi centre study is to evaluate an intervention, which means that patients undergoing radiotherapy for head and neck cancer will receive fixed dentures in accordance with the Public Health Care fee system…
- Conditions
- Head and Neck Neoplasms, Dental Prosthesis, Dentures, Quality of Life
- Trial name
- IMFDHAC (NCT03753932)
- Testing
- Fixed prosthodontics
- Where
- Sweden
- Volunteers
- 64 people
- Sponsor
- Region Jönköping County
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