Clinical trials: Health-related Quality of Life
Hepatitis C Infection
Outcomes in Liver Disease Patient With and Without HIV Co-infection-Sub Study 2: HCV Treatment: Health Related Quality
The main questions being addressed are (1) how patient reported outcomes change during treatment for HCV, (2) how treatment impacts liver function and liver status, and (3) how much treatment costs from the payer's perspective…
- Trial name
- NCT02427204
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Total Knee Replacement
Patellar Resurfacing Versus Patellar Retention in Total Knee Arthroplasty - A Randomized Clinical Trial
Background: Despite the excellent results of total knee replacement, also known as total knee arthroplasty (TKA) there is persistent controversy over whether or not to replace the surface of the kneecap.
- Trial name
- PROFIX (NCT01500252)
- Testing
- Patellar Replacement Prosthesis, Profix TKR with Patellar Retention
- Where
- Canada
- Volunteers
- 38 people
- Sponsor
- University of Alberta
Breast Neoplasms, Musculoskeletal Pain
Multicomponent Care for Aromatase Inhibitor-Related Musculoskeletal Symptoms
Breast cancer patients who receive endocrine therapy particularly aromatase inhibitors often experience aromatase inhibitors associated symptoms (AIMSS) such as joint and muscle pain along with stiffness and fatigue that can…
- Conditions
- Breast Neoplasms, Musculoskeletal Pain, Arthralgia, Musculoskeletal Diseases
- Trial name
- AIMSS-CARE (NCT07409948)
- Testing
- Multicomponent Care for Aromatase Inhibitor-Related Musculoskeletal Symptoms (AIMSS-CARE)
- Volunteers
- 88 people
- Sponsor
- Addis Ababa University
Eating Disorder NOS
ASSESSMENT OF ORAL HEALTH AND ORAL HEALTH-RELATED QUALITY OF LIFE IN PATIENTS AGED 12-18 YEARS WITH EATING DISORDERS
Although numerous instruments are available to assess oral health-related quality of life (OHRQoL) in adults, there is a paucity of studies evaluating the impact of oral health on quality of life in children and adolescents.
- Trial name
- NCT07896707
- Testing
- general oral health interventions and scales
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Diabetes Mellitus, Periodontal Diseases
Periodontal Health and Its Impact on Oral Health-related Quality of Life Among Diabetes Mellitus Patients
Periodontal diseases, encompassing a range of inflammatory conditions affecting the supporting structures of the teeth, have long been recognized as a prevalent comorbidity in individuals with diabetes.
- Trial name
- NCT06125561
- Testing
- Probing depth and Clinical attachment loss
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Pakistan Institute of Medical Sciences
Patient Satisfaction Using Implant Retained Overdentures
Patient's Satisfaction of Mandibular Implant Supported Overdentures With Reduced Denture Base Extensions.
This study aimed to compare reduced (partially extended) denture bases with fully extended bases regarding patient satisfaction, oral health-related quality of life (OHRQoL), and masticatory efficiency.
- Trial name
- NCT06850558
- Testing
- Four parallel implants were installed in the interforaminal region
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Mansoura University
COPD
Impact of Fixed TRIple Therapy With Beclometasone/Formoterol/Glycopyrronium DPI (Trimbow® in NEXThaler Device) in Chronic Obstructive PulmoNary Disease in rEal-world Settings: Health-related Quality of Life Patient' eXpectations and characterisTics: the TriNEXT Study
This is an observational, prospective, multicentric, cohort study conducted in France to evaluate the QoL in COPD patients treated with TRIMBOW NEXThaler 88/5/9 in a routine clinical practice setting.
- Trial name
- TriNEXT (NCT05948891)
- Testing
- Beclometasone/Formoterol/Glycopyrronium 88 µg/5 µg/9 µg DPI (Trimbow® 88 µg/5 µg/9 µg in NEXThaler device)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Chiesi SAS
Endometriosis, Adenomyosis
Psychotherapy in Patients With Endometriosis: Cognitive Behavioral Therapy Versus Acceptance and Commitment Therapy
The aim of the present study is to compare two types of psychotherapeutic interventions in women with endometriosis and/or adenomyosis: cognitive behavioral therapy (CBT) and acceptance and commitment therapy (ACT).
- Trial name
- T-ENDO (NCT07907848)
- Testing
- Cognitive Behavioral Therapy (CBT), Acceptance and Commitment Therapy (ACT)
- Where
- Italy
- Volunteers
- 128 people
- Sponsor
- Fiammetta Cosci
Sedentary Lifestyle, Workplace
Effectiveness of a Workplace "Sit Less and Move More" Web-based Program in Spanish Office Employees (Walk@WorkSpain)
This study assesses the short and mid-term impacts of a workplace web-based intervention (Walk@WorkSpain, W@WS) on self-reported occupational sitting time, step counts, activity-related energy expenditure, physical risk factors…
- Conditions
- Sedentary Lifestyle, Workplace, Quality of Life, Intervention Study
- Trial name
- W@WS (NCT02960750)
- Testing
- A workplace "sit less and move more" web-based program for Spanish office employees, Active Comparison group
- Where
- 4 sites in Spain
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- University of Vic - Central University of Catalonia
Knee Osteoarthritis, Hip Osteoarthritis
Quality of Life Related to Health in Spa Users
Hypothesis: The spa therapy treatment could improve health-related quality of life (HRQOL) in subjects with knee and/or hip osteoarthritis, and patients with rheumatoid arthritis.
- Conditions
- Knee Osteoarthritis, Hip Osteoarthritis, Rheumatoid Arthritis
- Trial name
- NCT03952897
- Testing
- balneotherapy
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- University of Castilla-La Mancha
Multiple Sclerosis
Oral Carnosine for Neuromuscular Performance in Multiple Sclerosis
Low levels of tissue carnosine and mitochondrial dysfunction appears to accompany multiple sclerosis (MS), with oral carnosine might be applicable to tackle impaired bioenergetics and oxidative stress in MS, and perhaps win back…
- Trial name
- CARMUS (NCT03995810)
- Testing
- Carnosine, capsulle, 2 g/day, 8 weeks
- Where
- Serbia
- Volunteers
- 3 people
- Sponsor
- University of Novi Sad, Faculty of Sport and Physical Education
Angina (Stable), Ischemic Heart Disease (IHD)
Angina After PCI: a Systems Medicine Study
Angina may persist or recur in patients treated by coronary angioplasty. The angioplasty involves a balloon treatment to open a blocked heart blood vessel and usually a stent (thin metal tube) is placed.
- Trial name
- CorMicA-PCI (NCT06854302)
- Testing
- Cardiovascular magnetic resonance imaging, Coronary physiology
- Where
- 4 sites in United Kingdom
- Volunteers
- 600 people
- Sponsor
- NHS National Waiting Times Centre Board
Overweight, Obesity
Long-term Health and Economic Effects of an Individualized Lifestyle Intervention (LI-PAD-Extended)
The goal of this clinical trial is to learn if an individualized lifestyle intervention works to improve weight, diet, physical activity, cardiovascular health, health-related quality of life, and cost-effectiveness in overweight…
- Conditions
- Overweight, Obesity, Prediabetic State
- Trial name
- LI-PAD-EXTENDE (NCT07605169)
- Testing
- Individualized physical activity and diet
- Where
- Sweden
- Volunteers
- 103 people
- Sponsor
- Vastra Gotaland Region
Neurogenic Bladder Dysfunction
Health-related Quality of Life of Patients With Neurogenic Bladder
Bladder management has a major impact on the quality of life in patients with neurogenic bladder dysfunction. This a prospective investigation of the effects of the method for bladder evacuation on the health-related quality of…
- Trial name
- NCT02179073
- Where
- Switzerland
- Volunteers
- 87 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
Quality of Life
Development of Urdu Version of Short Form 36 Health Questionnaire
Quality of life (QOL) is an overarching term for the quality of the various domains in life. It is a standard level that consists of the expectations of an individual or society for a good life.
- Trial name
- NCT04521257
- Where
- 2 sites in Pakistan
- Volunteers
- 80 people
- Sponsor
- Riphah International University
Pulmonary Hypertension: Efficacy of Rehabilitation
Pulmonary Hypertension: Efficacy of a 3 Week Inpatient Rehabilitation on Physical Condition, Body Composition and Health Related Quality of Life
Pulmonary hypertension (PH) leads to impaired physical condition (PC), body composition (BC) and health-related quality of life (HRQOL).
- Trial name
- NCT01650857
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hannover Medical School
Orofacial Pain, Sleep Bruxism
Orofacial Pain and Oral Health-Related Quality of Life in Musicians in German Amateur Orchestras
This cross-sectional online survey investigates the prevalence of orofacial pain, sleep-related problems, and oral health-related quality of life (OHRQoL) among adult musicians who play in German amateur orchestras.
- Conditions
- Orofacial Pain, Sleep Bruxism, Oral Health Related Quality of Life (OHRQoL)
- Trial name
- OSQ-MUS (NCT07714837)
- Testing
- Questionaire
- Where
- Germany
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University Medical Center Goettingen
Head and Neck Cancer
Quality-Of-Life Assessment in Patients With Head and Neck Cancer Treated With Radiation Therapy
RATIONALE: Gathering information over time about patients' quality-of-life and satisfaction with care may help doctors plan the best treatment and help patients live more comfortably.
- Trial name
- NCT01210872
- Testing
- questionnaire administration, quality-of-life assessment, standard follow-up care
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Georges Francois Leclerc
Stroke
Effects of PlayStation®VR on the HRQOL in Stroke Patients Undergoing Inpatient Rehabilitation
Compared to conventional rehabilitation therapy, the full-immersive commercial game (CG) system, in the form of available video game, could safely provide more positive effect on health-related quality of life (HRQOL) and motor…
- Trial name
- NCT04441177
- Testing
- PlayStation®VR training
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Chang Gung Memorial Hospital
Endometriosis, Endometriosis (Diagnosis)
Effect of Fish-Derived Lipids in Women With Endometriosis
Endometriosis is a chronic inflammatory gynecological disease that may be associated with pelvic pain, painful menstruation, reduced quality of life, impaired daily functioning, and changes in nutritional and metabolic health.
- Trial name
- fish-endo (NCT07800442)
- Testing
- Fish-derived lipid supplementation, Diet based on the Healthy Eating Plate recommendations
- Where
- Poland
- Volunteers
- 46 people
- Sponsor
- Angelika Bogusz
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