Clinical trials: Health-related Quality of Life
Quality of Life
Health-related QoL Following TAVI TAo, TAVI TF and AVR
The aim of the study was to evaluate short- and long-term changes in QoL in patients undergoing TAVI and to assess differences in patient QoL when using the TAVI TAo approach compared with the transfemoral approach (TAVI TF) and…
- Trial name
- NCT03583398
- Testing
- transcatheter aortic valve implantation, surgical aortic valve replacement
- Volunteers
- 97 people
- Sponsor
- Medical University of Gdansk
Edentulism, Edentulism Complete
Masticatory Efficiency, Bite Force, and Patient-Reported Outcomes in Patients Rehabilitated With Complete and Partial Dentures Supported by Teeth, Mini-Implants, or Conventional Implants
This study aims to evaluate masticatory efficiency, bite force, and patient-reported outcomes in edentulous and partially edentulous patients rehabilitated with different removable prosthodontic treatment modalities.
- Conditions
- Edentulism, Edentulism Complete, Partial Edentulism, Complete Dentures
- Trial name
- IMPROSTREHAB (NCT07639112)
- Where
- 2 sites in Croatia
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Crohn's Disease
A Crohn's Disease Diet to Reduce Symptoms of Crohn's Disease
A 16-week randomized, pilot study to determine if an elimination diet reduces symptoms of Crohn's disease. Sixty (60) adult patients (18-75 yrs) with a mild or moderate Crohn's Disease Activity Index (CDAI) of 150-450, will be…
- Trial name
- NCT01897090
- Testing
- Elimination Diet, Dietary Guidelines for Americans
- Where
- United States
- Sponsor
- Johns Hopkins University
Physical Activity
Prosocial Behavior and Volunteerism to Promote Physical Activity in Older Adults
The purpose of this 12-month study is to compare how well two programs help older adults make physical activity a regular habit.
- Trial name
- NCT01528761
- Testing
- Prosocial Behavior Physical Activity (PBPA), Healthy Aging (HA)
- Where
- United States
- Volunteers
- 317 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Pulmonary Disease, Chronic Obstructive
Targeted Nutrient Supplement in COPD (NUTRECOVER-trial)
The overall objective is to investigate the efficacy of targeted nutrient supplementation on daily physical activity level as well as generic health status in patients with COPD.
- Trial name
- NUTRECOVER (NCT03807310)
- Testing
- Targeted nutrient supplementation (Long-drink), Counselling
- Where
- Netherlands
- Volunteers
- 166 people
- Sponsor
- Maastricht University Medical Center
Primary Open Angle Glaucoma, Ocular Hypertension
Laser-1st vs Drops-1st for Glaucoma and Ocular Hypertension
This is a randomized study with two treatment arms: 'initial Selective Laser Trabeculoplasty (SLT) followed by conventional medical therapy as required' ('Laser-1st') and 'medical therapy without laser ('Medicine-1st').
- Trial name
- LIGHT (NCT03395535)
- Testing
- Primary Selective Laser Trabeculoplasty Treatment Pathway, Primary Medical Treatment Pathway
- Where
- United Kingdom
- Volunteers
- 718 people
- Sponsor
- Moorfields Eye Hospital NHS Foundation Trust
Delirium, Neurocognitive Disorders
Patient-reported Outcome Measures After Post-anesthesia Care Unit Delirium
To assess self-reported cognitive function and health-related quality of life in patients with and without early postoperative delirium
- Trial name
- NCT04168268
- Where
- Germany
- Volunteers
- 222 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Esophageal Achalasia
A Randomized Comparison of Laparoscopic Myotomy and Pneumatic Dilatation for Achalasia
The purpose of this study is to compare pneumatic dilatation and laparoscopic Heller myotomy in patients with achalasia in order to learn which of these two treatments should be recommended to patients in the future.
- Trial name
- NCT00188344
- Testing
- pneumatic dilatation, laparoscopic myotomy with partial fundoplication
- Where
- 2 sites in Canada
- Volunteers
- 56 people
- Sponsor
- University Health Network, Toronto
Chronic Respiratory Failure
Prognosis in Patients With Chronic Respiratory Failure Receiving Domiciliary Noninvasive Positive Pressure Ventilation (NPPV)
The purposes of the present study are (1) to analyze baseline patient characteristics cross-sectionally, (2) to analyze the prognosis and its predictive factors, and (3) to examine longitudinal clinical course in patients with…
- Trial name
- NCT00905476
- Where
- 11 sites in Japan
- Volunteers
- 56 people
- Sponsor
- Kyoto University, Graduate School of Medicine
Adherence, Medication, Chronic Disease
Efficacy of CareAide® App in Improving Adherence in Adults With Chronic Diseases
The goal of this clinical trial is to study the impact of a medication adherence app, CareAide, in adult population diagnosed with chronic diseases in Malaysian population. The main question[s] it aims to answer are: 1.
- Conditions
- Adherence, Medication, Chronic Disease, Quality of Life, Economic Burden
- Trial name
- CAREAide (NCT06068309)
- Testing
- CareAide App Usage
- Where
- 3 sites in Malaysia
- Volunteers
- 900 people
- Sponsor
- University of Malaya
Child
Impact of Cancer on the Physical and Psychological Well-being of Children in Mainland China
The aim of this study is to explore the impact of cancer and therapy-related symptoms on Mainland Chinese children's physical and psychological well-being.
- Trial name
- NCT02928731
- Testing
- Questionnaires set 1, Questionnaires set 2
- Where
- China
- Volunteers
- 425 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Childhood Osteosarcoma
The Impact of Cancer on the Physical and Psychosocial Well-being Among Childhood Osteosarcoma Survivors
The aim of the study is to examine the impact of cancer and treatment-related effects on the physical and psychosocial well-being and quality of life among Hong Kong Chinese survivors of childhood osteosarcoma.
- Trial name
- NCT03298971
- Testing
- Questionnaires
- Where
- Hong Kong
- Volunteers
- 240 people
- Sponsor
- The University of Hong Kong
Depression and Quality of Life
ICBT for Mental Health Problems Related to the Climate Crisis
The study seeks to investigate the effects of a guided internet-based cognitive behavioral therapy (ICBT) programme on adult mental health problems related to the climate crisis.
- Trial name
- NCT05169736
- Testing
- Cognitive Behavioural Therapy
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Linkoeping University
Opioid Use Disorder, Opioid Withdrawal
Medically Supervised Ibogaine With 12-Month Digital Recovery Support for Opioid Use Disorder
IBO-CARE is a single-site Phase 1/2a study evaluating the safety, tolerability, feasibility and preliminary outcomes of medically supervised ibogaine with 12 months of recovery support in adults with moderate-to-severe opioid use…
- Conditions
- Opioid Use Disorder, Opioid Withdrawal, Substance Use Disorders
- Trial name
- IBO-CARE (NCT07871877)
- Testing
- Ibogaine Hydrochloride, Extended-release naltrexone injection, 380 mg, My-E-Health SENTINEL Digital Monitoring and Human-Gated Escalation Platform
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Clive Michelsen
Neurofibromatosis
Relationship Between Psychosocial Factors, Health Literacy, Quality of Life and Satisfaction With Medical Visits in Adults With NF
This is a prospective study through the NF clinic at Massachusetts General Hospital that will examine the relationship between psychosocial factors, health literacy, and satisfaction with the medical visit in adults with NF1…
- Trial name
- NCT02435628
- Testing
- Questionnaires
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
COVID-19 Infection, Hematopoietic and Lymphoid Cell Neoplasm
Well-Being and Health-Related Quality of Life in Cancer Patients and Survivors During the COVID-19 Pandemic
This study investigates the well-being and health-related quality of life in cancer patients and survivors during the COVID-19 pandemic.
- Conditions
- COVID-19 Infection, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
- Trial name
- NCT04500600
- Testing
- Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 13,378 people
- Sponsor
- M.D. Anderson Cancer Center
Oral Health Related Quality of Life (OHRQoL)
New Functional Ingredient for Oral Care
The goal of this clinical trial is to find new ingredients for oral care products that can improve gum health. We want to learn if new botanical blends can help reduce gum inflammation, strengthen the gum's natural barrier, and…
- Trial name
- NCT07771907
- Testing
- Botanical A, Botanical B
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Access Business Group
Cardiovascular Diseases, Hypertension
IV Hydrogen Nanobubbles for Cardiac Function and QoL
The goal of this clinical trial is to learn if intravenous hydrogen nanobubbles (HNBs) improve cardiovascular function and quality of life in adults.
- Conditions
- Cardiovascular Diseases, Hypertension, Blood Pressure
- Trial name
- HNB (NCT07085637)
- Testing
- intravenous infusion of hydrogen nanobubbles (HNB) administered twice weekly over a 5-week period
- Where
- Indonesia
- Volunteers
- 52 people
- Sponsor
- Indonesia Molecule Institute
Obesity and Obesity-related Medical Conditions
"F!reF!ghterF!t": Lifestyle Coaching Interventions for Obese Firefighters (FireFit)
Our goal is to explore the effectiveness of 9- month lifestyle medicine based coaching intervention (individual and group coaching) versus control (usual care/ written health instructions).
- Trial name
- FireFit (NCT06890975)
- Testing
- Lifestyle Coaching
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Cambridge Health Alliance
Ischemic Heart Disease
Ozone Therapy in Refractory Ischemic Heart Disease.
The main objective of this clinical trial is to evaluate the effectiveness and cost-effectiveness of adding ozone therapy to standard management of patients with advanced ischemic heart disease refractory to medical and surgical…
- Trial name
- O3Cardio (NCT03660657)
- Testing
- Ozone, Oxygen
- Where
- Spain
- Volunteers
- 1 people
- Sponsor
- Bernardino Clavo, MD, PhD
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