Clinical trials: Health-related Quality of Life
Cognitive Impairment
Virtual Reality-Assisted Reminiscence Therapy in Older Adults With Cognitive Impairment
This study evaluated whether immersive virtual reality (VR) could enhance the effects of reminiscence therapy in older adults with cognitive impairment attending day-care services.
- Trial name
- NCT07825909
- Testing
- Virtual Reality-Assisted Reminiscence Therapy, Traditional Reminiscence Therapy
- Where
- 2 sites in Italy
- Volunteers
- 60 people
- Sponsor
- Istituto Universitario Salesiano Venezia-Mestre (IUS)
Thyroid Diseases
Health-Related Quality of Life for Thyroid Patients
Background: Thyroid diseases are frequent. They include both metabolic changes and gland enlargement (goitre). Previous research and clinical suspicion indicate that the life quality of many patients is reduced despite successful…
- Trial name
- NCT00150033
- Where
- Denmark
- Volunteers
- 1,200 people
- Sponsor
- Odense University Hospital
Pain and Discomfort, Orthodontic Appliance Complication
The Role of Paracetamol-caffeine and Laser Irradiation on Controlling Pain and Discomfort During Orthodontic Treatment
Patients with class I malocclusion who have mild to moderate crowding will be treated in this study. The efficacy of low level laser therapy and Panadol-extra® in relieving pain due to orthodontic treatment will be assessed.
- Trial name
- NCT03400111
- Testing
- low-level laser therapy, Panadol-extra
- Where
- Syria
- Volunteers
- 60 people
- Sponsor
- Damascus University
Desmoid Tumor, Quality of Life
Burden of Disease and Living Situation in Desmoid Patients
The main aim of the study is to assess the situation and quality of life of desmoid patients. Impaired areas of quality of life and the associated factors are to be identified.
- Trial name
- PROSa Desmoid (NCT06258421)
- Testing
- No Intervention
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Technische Universität Dresden
Exercise, Metabolic Syndrome
Exercise Effects on Health Status in Patients With Severe Mental Illness
People with severe mental disorders have a mortality rate 2 to 3 times higher than that of the general population, largely due to the presence of comorbidities, with a predominance of cardiovascular disease.
- Conditions
- Exercise, Metabolic Syndrome, Mental Disorders, Severe, Severe Mental Disorder
- Trial name
- SMI01 (NCT05834309)
- Testing
- Physical exercise
- Where
- 2 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Universidad Pública de Navarra
Psychosocial, Cervical Cancer
Patient Satisfaction & Quality Of Life in Patients With Cervical Cancer
Primary Objectives: 1. To compare levels of patient anxiety, pain, and satisfaction associated with optical spectroscopy procedures and MDC with the levels associated with colposcopically-directed biopsy in the cervical cancer…
- Trial name
- NCT00473798
- Testing
- Questionnaire
- Where
- 5 sites in United States, Canada
- Volunteers
- 1,938 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Mild Cognitive Impairment, Insomnia
A Mixed Method Pilot Study for Patients With Mild Cognitive Impairment and Insomnia.
Dementia is irreversible, incurable and devastating. It is thus imperative to preserve cognition at the pre-dementia stage. Mild cognitive impairment (MCI) refers to the reversible intermediate clinical state between normal…
- Trial name
- NCT04635085
- Testing
- Empowerment-based Cognitive behavioral therapy for insomnia for MCI
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The University of Hong Kong
Dentin Sensitivity
A Real-World Evidence Study Evaluating Oral Health Related Quality Of Life With Use Of A Stannous Fluoride Anti-Sensitivity Toothpaste For Dentin Hypersensitivity Management
This study will evaluate the impact of long-term use of a desensitizing toothpaste containing 0.454 percent (%) stannous fluoride (SnF2) on oral health related quality of life (OHrQoL) in a population of self-reported dentin…
- Trial name
- NCT06045026
- Testing
- Stannous fluoride
- Where
- United States
- Volunteers
- 536 people
- Sponsor
- HALEON
Thyroid Neoplasms
Testing a Web-based Intervention for Radioactive Iodine Symptom Management to Improve Health-related Quality of Life Among Differentiated Thyroid Cancer Patients
The goal of this clinical trial is to learn if adult patients diagnosed with differentiated thyroid cancer can easily use and benefit from an online tool aimed to provide patients with educational resources and symptom management…
- Trial name
- NCT06853925
- Testing
- Radioactive Iodine Support (RAI Support), Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Georgetown University
Chronic Obstructive Pulmonary Disease
Arm Training in Patients With Chronic Obstructive Pulmonary Disease
Patients with chronic lung disease often report shortness of breath when they use their arms for simple activities of daily living such as dressing, lifting, shaving, bathing and brushing their hair and teeth.
- Trial name
- NCT00657293
- Testing
- Arm training program
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- West Park Healthcare Centre
Dental Caries, Gingivitis
Parental Perception of Oral Health-Related Quality of Life in Sudanese Refugee vs. Egyptian Children
This cross-sectional analytical study aims to assess and compare parental perceptions of oral health-related quality of life (OHRQoL) among Sudanese refugee children and Egyptian children aged 6-12 years living in Egypt.
- Conditions
- Dental Caries, Gingivitis, Oral Health, Refugee Health
- Trial name
- NCT07011381
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Breast Neoplasms
Healing Touch and Health-Related Quality of Life in Women With Breast Cancer Receiving Radiation Therapy
The purpose of this study is to evaluate the effectiveness of Healing Touch to improve health-related quality of life in women with breast cancer receiving radiation therapy.
- Trial name
- NCT00612443
- Testing
- Healing Touch
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Wisconsin, Milwaukee
COPD
Brisk Walk on Chronic Obstructive Pulmonary Disease
To determine the effects of 30 min brisk walk on Pulmonary Functions on COPD patients To determine the effects of 30 min brisk walk on Health related Health-related quality of life (HRLQ) on Chronic obstructive pulmonary disease…
- Trial name
- NCT05052047
- Testing
- Brisk Walking Group, Conventional Breathing Exercise Group
- Where
- Pakistan
- Volunteers
- 74 people
- Sponsor
- Riphah International University
Crohn's Disease
A Crohn's Disease Diet to Reduce Symptoms of Crohn's Disease
A 16-week randomized, pilot study to determine if an elimination diet reduces symptoms of Crohn's disease. Sixty (60) adult patients (18-75 yrs) with a mild or moderate Crohn's Disease Activity Index (CDAI) of 150-450, will be…
- Trial name
- NCT01897090
- Testing
- Elimination Diet, Dietary Guidelines for Americans
- Where
- United States
- Sponsor
- Johns Hopkins University
Chronic Fatigue Syndrome
Coenzyme Q10 Plus NADH Supplementation in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis
The main aim of the study is to examine the effect of oral CoQ10 plus NADH (Reconnect®) supplementation twice daily for 8-weeks on the changes in fatigue perception, sleep disturbances, autonomic dysfunction and HRQoL assessed by…
- Trial name
- CONNeCT (NCT03186027)
- Testing
- Coenzyme Q10 plus NADH, phosphoserine plus vitamin C
- Where
- Spain
- Volunteers
- 282 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Metastatic Breast Cancer
Real-world Evidence Prospective Study on the Effect of Nab-paclitaxel Treatment on the Clinical Outcomes and HRQoL in Patients With MBC in Greece
This non-interventional study aims at assessing the impact of nab-paclitaxel on the clinical outcomes and the health-related QoL (HRQoL) of this heavily burdened and difficult-to-treat population.
- Trial name
- ABReast (NCT02626013)
- Where
- Greece
- Volunteers
- 156 people
- Sponsor
- Genesis Pharma S.A.
Rheumatoid Arthritis
An Observational Study to Assess the Impact of Upadacitinib in Adult Hungarian Participants With Moderate to Severe Rheumatoid Arthritis (RA) in Real-World Practice
Rheumatoid Arthritis (RA) is a chronic inflammatory disease causing pain, stiffness, swelling and loss of joint function. Despite the range of treatment options for RA steadily increasing, many patients remain sub-optimally…
- Trial name
- UPDATE (NCT05327920)
- Where
- 8 sites in Hungary
- Volunteers
- 93 people
- Sponsor
- AbbVie
Type 2 Diabetes, Mental Health Issue
Community-based CBT and T2D in Latino Population
The purpose of this project is to develop and test the acceptance and clinical efficacy of a cognitive behavioral therapy (CBT)-based lifestyle intervention, to help manage obesity and diabetes-related health outcomes, provided…
- Conditions
- Type 2 Diabetes, Mental Health Issue, Quality of Life, Weight Loss
- Trial name
- NCT05222373
- Testing
- CBT-based lifestyle intervention
- Where
- United States
- Sponsor
- Washington University School of Medicine
Cerebral Palsy
Participation to Life of Children With Cerebral Palsy
Cerebral Palsy (CP) defined as a group of permanent impairments that is originating from non-progressive disorders that develop in the immature brain. CP leads activity limitations of movement and posture development.
- Trial name
- PLCC (NCT03191695)
- Testing
- Assessment via questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Hacettepe University
Post Traumatic Stress Disorder (PTSD), Depressive Symptoms
The Norwegian Stepped-Care TF-CBT Study
Every day, a significant number of children and young people in Norway experience violence, abuse, or other potentially traumatizing events.
- Conditions
- Post Traumatic Stress Disorder (PTSD), Depressive Symptoms, Parental Stress, Health Related Quality of Life
- Trial name
- NCT04073862
- Testing
- Stepped-Care TF-CBT
- Where
- Norway
- Volunteers
- 82 people
- Sponsor
- Norwegian Center for Violence and Traumatic Stress Studies
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