Clinical trials: Health-related Quality of Life
Cerebral Palsy
Correlation Physiological Cost Index
Objective: To compare the efficacy of a gait training program using robotic assistance combined with virtual reality versus robotic assistance alone on energy expenditure in children with cerebral palsy.
- Trial name
- CPCI (NCT03700073)
- Testing
- Experimental group (GTVR), Control group (GT)
- Where
- Spain
- Volunteers
- 26 people
- Sponsor
- Cardenal Herrera University
Oesophageal Cancer
Physical Activity Intervention Trial to Mitigate Muscle Loss and Increase Muscle Strength
This intervention study will be conducted on patients included in a nationwide and prospective cohort, The Oesophageal Surgery in Cancer patients: Adaptation and Recovery study (OSCAR).
- Trial name
- NCT02774551
- Testing
- Physical activity intervention group
- Where
- Sweden
- Volunteers
- 162 people
- Sponsor
- Karolinska Institutet
Systemic Sclerosis (SSc)
Home-based Exercise for Improving Health-related Quality of Life in Systemic Sclerosis
The goal of this randomised controlled trial is to evaluate whether a partially supervised, home-based exercise programme in addition to usual care improves health-related quality of life in adults with systemic sclerosis.
- Trial name
- ScleroStrong (NCT07840430)
- Testing
- Home-based exercise programme, Usual Care
- Where
- 3 sites in Denmark
- Volunteers
- 270 people
- Sponsor
- University of Aarhus
Pediatric ALL
Assessing Neurophysiological and Cognitive Function in School Children
This trial will investigate the feasibility of implementing our novel assessment battery in a neurodiverse pediatric population.
- Trial name
- WIS (NCT06209528)
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Life University
Hematopoietic Stem Cell Transplant
Early Cognitive Behavioral Therapy for Insomnia (CBT-I) in People Planning to Under Hematopoietic Stem Cell Transplant (HSCT)
This proposed study is a prospective, randomized, controlled Phase 1 clinical trial to determine feasibility, acceptability (Aim 1) and preliminary effect (Aim 2) to mitigate insomnia symptoms and fatigue and improve…
- Trial name
- NCT07774039
- Testing
- Cognitive behavioral therapy for insomnia (CBT-I)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Kansas Medical Center
Age-related Cognitive Decline, Cognitive Deterioration
Decoding the Cognitive Trajectory of Hong Kong SuperAgers: a Longitudinal Follow-up Study
This is a prospective follow-up study conducted at the Department of Psychiatry, The Chinese University of Hong Kong. The participants, including high-performing elderly (SuperAgers), normal ageing elderly and neurocognitive…
- Conditions
- Age-related Cognitive Decline, Cognitive Deterioration, Dementia, Mild
- Trial name
- NCT05728801
- Testing
- Ageing
- Where
- Hong Kong
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Marfan Syndrome, Marfan Syndrome Cardiovascular Manifestations
Living With Marfans and Your Aorta: Surgical Outcomes Study
Marfan Syndrome (MFS) is a genetic disease affecting the eyes, skeleton, heart and arteries. Despite MFS affecting multiple organ systems, cardiovascular manifestations are the most serious and life threatening.
- Trial name
- LIMA II (NCT04776681)
- Where
- United Kingdom
- Volunteers
- 28 people
- Sponsor
- Barts & The London NHS Trust
Chronic Pain, Musculoskeletal Pain
National Survey of Chronic Occupational Pain in Thai Anesthesia Providers
The purpose of this nationwide cross-sectional survey is to determine the prevalence, multidimensional impacts, and associated factors of chronic occupational pain among anesthesiologists and nurse anesthetists in Thailand.
- Conditions
- Chronic Pain, Musculoskeletal Pain, Occupational Pain, Occupational Diseases
- Trial name
- NCT07778381
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Limb-Girdle Muscular Dystrophy, Social Competence
Telecare Psychosocial and Cognitive Intervention for Children and Adolescents With Limb-Girdle Muscular Dystrophy
This clinical trial aims to evaluate the efficacy of a telecare-mediated psychosocial and cognitive intervention for children and adolescents aged 7 to 17 with limb-girdle muscular dystrophy.
- Conditions
- Limb-Girdle Muscular Dystrophy, Social Competence, Self Esteem, Health Related Quality of Life
- Trial name
- TPCLGMD (NCT07711730)
- Testing
- Neuro-psychosocial teleassistance program
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- University of Deusto
Health Services Research, Quality of Life
Quality of Life and Addiction Among Hospital Night Workers
The current context of the Covid-19 health crisis leads to an over-solicitation of health systems, with hospital staff in the front line.
- Conditions
- Health Services Research, Quality of Life, Addiction, Substance-Related Disorders
- Trial name
- ALADDIN (NCT04291534)
- Where
- 2 sites in France
- Volunteers
- 1,800 people
- Sponsor
- University Paris 7 - Denis Diderot
Quality of Life
Preventive Program for Work-Related Musculoskeletal Disorders
Introduction: Work-Related Musculoskeletal Disorders (WMSDs) are characterized by inflammation of muscles, tendons, fascia and nerves of upper limbs, shoulder girdle and neck.
- Trial name
- NCT02552680
- Testing
- Exercise, Guideline, Brochure
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Bilateral Edentulous Mandible (Kennedy Class I)
Treatment Outcomes After Receiving Conventional Clasp or Precision Attachment Removable Partial Dentures.
PICOTS: P: Kennedy class І patients I : Mandibular removable partial denture with OT Cap attachment C: Mandibular removable partial denture with gingival approaching clasp assembly O: 1ry outcome: Oral Health Related Quality of…
- Trial name
- OTCap (NCT02924142)
- Testing
- OT Cap attachment
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
Chronic Obstructive Pulmonary Disease
Multidimensional Individualized Nutritional Therapy for Individuals with Severe COPD
Individuals with severe chronic pulmonary disease often life isolated with a high burden of symptoms. Nutritional risk and low quality of life are common, and both associated with increased societal cost and poor prognosis.
- Trial name
- MINDNUT (NCT04873856)
- Testing
- Intervention
- Where
- Denmark
- Volunteers
- 87 people
- Sponsor
- Nordsjaellands Hospital
Cancer-related Problem/Condition, Cancer-related Fatigue
Engagement and Acceptability of the Untire mHealth App
The aim of this study will be to assess the engagement and acceptability of the Untire mHealth intervention for adults with cancer related fatigue. Acceptability will be assessed after 2, 4, 6 and 12 weeks of app use.
- Trial name
- NCT05891431
- Testing
- Untire mobile app
- Where
- 2 sites in United Kingdom
- Volunteers
- 34 people
- Sponsor
- University of Bath
Post-Intensive Care Syndrome (PICS)
ICU Biobank: Understanding Post-Intensive Care Syndrome (PICS)
The goal of this observational study is to explore the development and progression of Post-Intensive Care Syndrome (PICS) in adult ICU patients by establishing a biobank of biological samples and outcome data.
- Trial name
- NCT06671795
- Where
- Austria
- Volunteers
- 400 people
- Sponsor
- Medical University of Vienna
Critically Ill
Cost-effectiveness of Extracorporeal Life Support Treatment
This study evaluates patients on ECLS treatment as considered appropriate with mortality and health related Quality of life and costs.
- Trial name
- NCT02837419
- Testing
- Health related Quality of life EQ-5D
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- University Medical Center Groningen
Heart Transplant Patients, Kidney Transplant Patients
Multidisciplinary Non-Pharmacological Intervention to Improve Quality of Life in Solid Organ Transplant Recipients
This is a single-center interventional study aimed at evaluating the feasibility of a multidisciplinary non-pharmacological approach based on acupuncture, telerehabilitation-based physical rehabilitation, and brain health…
- Conditions
- Heart Transplant Patients, Kidney Transplant Patients, Lung Transplant, Liver Transplanted Patients
- Trial name
- TAO (NCT07870811)
- Testing
- Acupuncture, Telerehabilitation-Based Physical Rehabilitation, Psychological Support Program
- Where
- Italy
- Volunteers
- 140 people
- Sponsor
- The Mediterranean Institute for Transplantation and Advanced Specialized Therapies
Breast Cancer
Ethnic Differences in the Impact of Breast Cancer on Employment Status, Financial Situation, and Quality of Life
The purpose of this study is to learn more about how being treated for breast cancer affects patients' employment, financial situation, and quality of life on a short-term basis and on a long term basis.
- Trial name
- NCT01134172
- Testing
- survey web-based or telephone interview
- Where
- 12 sites in United States
- Volunteers
- 935 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Childhood Osteosarcoma
The Impact of Cancer on the Physical and Psychosocial Well-being Among Childhood Osteosarcoma Survivors
The aim of the study is to examine the impact of cancer and treatment-related effects on the physical and psychosocial well-being and quality of life among Hong Kong Chinese survivors of childhood osteosarcoma.
- Trial name
- NCT03298971
- Testing
- Questionnaires
- Where
- Hong Kong
- Volunteers
- 240 people
- Sponsor
- The University of Hong Kong
Rheumatic Diseases
Patient-Reported Outcomes Measurement Information System Integration Into Rheumatology Clinical Practice
This study will examine the impact of providing patient-reported outcomes measurement information system (PROMIS) scores to patients before appointments with their healthcare provider.
- Trial name
- NCT05026853
- Testing
- PRO Integration into Clinical Practice
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Michigan
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