Clinical trials: Health-related Quality of Life
Breast Cancer, Quality of Life
Compare Adjuvant Monotherapy With Endocrine or Accelerated Partial Breast Irradiation After Lumpectomy
The aim of this prospective study is to investigate quality of life and oncologic outcomes in low-risk elderly breast cancer patients randomized to adjuvant therapy with accelerated partial breast irradiation (APBI) alone or…
- Trial name
- CAMERAN (NCT05472792)
- Testing
- Accelerated Partial Breast Irradiation (APBI), tamoxifen, anastrozole, exemestane, letrozole, fulvestrant, toremifene
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Coronary Microvascular Disease
Exercise and Coronary Microvascular Disease
Exercise CMD is a prospective single-center, open-label, parallel arms randomized controlled trial. This trial aims to assess the impact of cardiac rehabilitation on top of optimal medical therapy on patient-reported outcomes in…
- Trial name
- ExerciseCMD (NCT05810051)
- Testing
- Cardiac rehabilitation
- Where
- Belgium
- Volunteers
- 204 people
- Sponsor
- CoreAalst BV
Geriatrics
Comparative Effects of Modified Otago and Frenkel's Exercises in Geriatric Population
The goal of this randomized clinical trial is to compare the effects of modified Otago and Frenkel's exercises on balance, motor function, fear of fall and quality of life in the geriatric population.
- Trial name
- NCT06460337
- Testing
- Modified Otago exercises, Frenkel's exercises
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Hemophilia A
Patient-reported Outcomes in Subjects Treated With ReFacto AF Routine Prophylaxis
This NIS aims to assess the patient-reported outcomes (PROs) in enrolled subjects
- Trial name
- NCT02718677
- Testing
- Refacto AF
- Sponsor
- Pfizer
Quality of Life
Effects of a Clinical Pharmacist Service on Health-related Quality of Life
The aim of the present study is to evaluate effects of a clinical pharmacist service on health-related quality of life and prescribing of drugs.
- Trial name
- NCT01016301
- Testing
- Pharmacist service
- Where
- Sweden
- Volunteers
- 400 people
- Sponsor
- Sahlgrenska University Hospital
Focal Segmental Glomerulosclerosis, Immunoglobulin A Nephropathy
Humanistic Burden of (FSGS) Focal Segmental Glomerulosclerosis and IgAN (Immunoglobulin A Nephropathy)
The aim of this observational study is to assess humanistic burden among adults and children/adolescents with FSGS and IgAN as well as the burden and impact for patient care-partners in six countries (United States [US], United…
- Trial name
- HONUS (NCT05200871)
- Where
- 6 sites in United States, Germany and 1 more
- Volunteers
- 487 people
- Sponsor
- Travere Therapeutics, Inc.
Dental Caries, Gingivitis
Parental Perception of Oral Health-Related Quality of Life in Sudanese Refugee vs. Egyptian Children
This cross-sectional analytical study aims to assess and compare parental perceptions of oral health-related quality of life (OHRQoL) among Sudanese refugee children and Egyptian children aged 6-12 years living in Egypt.
- Conditions
- Dental Caries, Gingivitis, Oral Health, Refugee Health
- Trial name
- NCT07011381
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Dementia, Family Caregivers
Dyadic Sport Stacking Program for Mild Dementia and Their Family Caregivers
The goal of this clinical trial is to develop and test a dyadic empowerment-based sport stacking program to improve health outcomes of people with mild dementia and their family caregivers.
- Conditions
- Dementia, Family Caregivers, Dyadic Intervention, Health Related Quality of Life
- Trial name
- NCT06597981
- Testing
- Dyadic empowerment-based sport stacking, Basic education
- Where
- China
- Volunteers
- 144 people
- Sponsor
- The University of Hong Kong
Domestic Violence, Intimate Partner Violence
The Relationship of Occupational Competence and Activity Role Participation to Life Satisfaction and Depression Severity in Women Exposed to Domestic Physical Violence at a Social Service Institution
The goal of this observational study is to examine the relationships between occupational competence, activity and role participation, life satisfaction, and depression severity in women aged 20-50 years who have experienced…
- Conditions
- Domestic Violence, Intimate Partner Violence, Depression, Activities of Daily Living
- Trial name
- NCT07454213
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Medipol University
Pain, Postoperative, Quality of Life
Efficacy of Two Local Anesthetics on Quality of Life After Endodontic Treatment
In this randomized controlled double-blinded study, subjects will be assigned to one of two study groups to either be anesthetized with Bupivacaine or Lidocaine prior to needed treatment of pulpectomy/endodontic debridement on a…
- Trial name
- B-OHIP14 (NCT04787731)
- Testing
- Bupivacaine Local Anesthetic
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- NYU College of Dentistry
Long COVID
Health-related Quality of Life and Long COVID
Background: Long COVID is estimated to affect 1.7 million people in the UK. One way of assessing the impact of long COVID is to measure quality-of-life through a standard questionnaire, which can then be used to understand the…
- Trial name
- OpenPROMPT (NCT05552612)
- Where
- United Kingdom
- Volunteers
- 7,574 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Scoliosis; Idiopathic, Infantile, Scoliosis; Juvenile
Physical Activity, Motor Competence, Pulmonary Function, and Quality of Life in Children With Severe Spinal Disease
Observation study about physical activity, motor competence, pulmonary function, and health related quality of life in children, surgically treated for early onset scoliosis
- Conditions
- Scoliosis; Idiopathic, Infantile, Scoliosis; Juvenile, Scoliosis Neuromuscular, Scoliosis in Neurofibromatosis
- Trial name
- NCT03494829
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Oslo University Hospital
Myopia
Observational Survey Study on the Impact of Myopia and Its Complications on Quality of Life.
This study aims to assess the impact of myopia in childhood and its long-term complications in adulthood on health-related Quality of Life (HRQoL), providing valuable data for cost-effectiveness models.
- Trial name
- NCT06912802
- Testing
- Non-Intervention
- Where
- 10 sites in Denmark, France and 5 more
- Volunteers
- 344 people
- Sponsor
- Santen SAS
Sarcopenia
Protein Supplementation and Muscle Function in the Elderly
Sarcopenia is a geriatric syndrome associated with functional lost and disability, leading to an increase in healthcare costs. Physical activity, especially multicomponent exercise program, seems to be the most effective…
- Trial name
- NCT03815201
- Testing
- Group 2, Group 1
- Where
- Spain
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Basque Health Service
Cardiac Sarcoidosis
Development and Validation of a Health-related Quality of Life Tool for Patients With Cardiac Sarcoidosis
What is the purpose of this research? This study includes two parts based in two NHS specialist centres for cardiac sarcoidosis: Development of the CARD-SARC: Development of the new questionnaire to measure quality of life in…
- Trial name
- NCT05145023
- Where
- 2 sites in United Kingdom
- Volunteers
- 130 people
- Sponsor
- Queen Mary University of London
Cystic Fibrosis
Evaluating the Impact of Chronic Rhinosinusitis on the Health-Related Quality of Life Among Adults With Cystic Fibrosis
Individuals with Cystic Fibrosis (CF) have a defective protein, which is known as the cystic-fibrosis transmembrane regulator (CFTR). The CFTR transports salt and hydrates mucous.
- Trial name
- NCT02003079
- Testing
- Cystic Fibrosis Questionnaire (Revised) for Teens/Adults
- Where
- Canada
- Volunteers
- 113 people
- Sponsor
- St. Paul's Hospital, Canada
Endometriosis
Effectiveness of an Adapted Physical Activity Program on Improving the Health-related Quality of Life of Women With Endometriosis in Martinique
There is no specific treatment for endometriosis, because the pathophysiology is poorly understood. Adapted physical activity (APA) is recognized as a beneficial supportive care for patients suffering from chronic pathology.
- Trial name
- APAENDO (NCT06776627)
- Testing
- Adapted physical activity (APA)
- Where
- France
- Volunteers
- 51 people
- Sponsor
- University Hospital Center of Martinique
Systemic Scleroderma
Efficacy and Safety of Allogenic Cultured Adipose-derived Mesenchymal Stromal Cell Injections on MoUth Fibrosis and Handicap in Patients With Systemic sclEroderma
Orofacial manifestations and microstomia are a frequent complication in systemic sclerosis (SSc) with a major impact on oral hygiene, dental care and quality of life.
- Trial name
- A-MUSE (NCT07326033)
- Testing
- AdMSC
- Where
- 5 sites in France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Toulouse
Post Traumatic Stress Disorder PTSD, Quality of Life
Effectiveness of Trauma Treatment in the Specialist Health Care Services
Post-traumatic stress disorder (PTSD) is a common mental illness. Treatments for PTSD are regarded as highly effective, but a large-scale, prospective, longitudinal randomized controlled trial comparing the effectiveness of these…
- Conditions
- Post Traumatic Stress Disorder PTSD, Quality of Life, Functional Outcome, Complex Post-Traumatic Stress Disorder
- Trial name
- NCT06691347
- Testing
- Eye movement desensitization and reprocessing, Cognitive therapy for PTSD
- Where
- Norway
- Volunteers
- 270 people
- Sponsor
- Vestre Viken Hospital Trust
Health Behavior
Effects of Individual, Dyadic, and Collaborative Plans on Physical Activity in Parent-Child Dyads
AIMS: The project aims at investigating of the effects of three types of planning (individual planning, collaborative planning, and dyadic planning) on physical activity.The influence of three planning interventions are compared…
- Trial name
- NCT02713438
- Testing
- Individual Planning, Dyadic Planning, Collaborative Planning
- Where
- Poland
- Volunteers
- 496 people, healthy volunteers welcome
- Sponsor
- University of Social Sciences and Humanities, Warsaw
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