Clinical trials: Healthcare Associated Infections
Multi Drug Resistant Infections, Pneumnia
Systemic Traditional Chinese Medicine in Multidrug-Resistant Bacterial Pneumonia
This is a multicenter prospective observational cohort study of hospitalized patients with multidrug-resistant bacterial pneumonia.
- Trial name
- MDRBP-TCM (NCT07726095)
- Where
- China
- Volunteers
- 528 people
- Sponsor
- Henan University of Traditional Chinese Medicine
Head Injury, Traumatic Brain Injury
Outcomes of Early Versus Late Tracheostomy in Critically Ill Patients Due to Head Injury: A Randomized Controlled Trial
Tracheostomy is a surgical procedure that involves creating an opening in the trachea and bringing it to the skin surface to form a stoma. It may be performed as an emergency or elective operation.
- Trial name
- NCT07872865
- Testing
- Tracheostomy
- Where
- Iraq
- Volunteers
- 100 people
- Sponsor
- University Of Anbar
Ventilator Acquired Pneumonia, Hospital Acquired Pneumonia
Steriwave ICU Pilot Study
This is a single-center, non-blinded, prospective, pilot study enrolling patients admitted to the critical care unit at Royal Columbian Hospital.
- Conditions
- Ventilator Acquired Pneumonia, Hospital Acquired Pneumonia, Hospital Acquired Infections, Nasal Decolonization of Staphylococcus Aureus
- Trial name
- NCT06867458
- Testing
- Antimicrobial photodynamic therapy (aPDT) nasal decolonization device
- Where
- Canada
- Volunteers
- 227 people
- Sponsor
- Fraser Health
Nontuberculous Mycobacterial Pulmonary Infection, Outbreak Investigation
Transmission and Acquisition of Nontuberculous Mycobacteria Outbreak Investigation (TrANsMIt)
The goal of this observational study is to support U.S. healthcare centers in determining if they may have an NTM outbreak among patients receiving care at the healthcare center.
- Conditions
- Nontuberculous Mycobacterial Pulmonary Infection, Outbreak Investigation, Healthcare Associated Infection, Mycobacterium Infections
- Trial name
- TrANsMIt (NCT06155747)
- Testing
- Epidemiologic investigation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of North Carolina, Chapel Hill
Nosocomial Pneumonia
High-dose Inhaled NO Therapy for the Prevention of Nosocomial Pneumonia After Cardiac Surgery With CPB
The primary aim of this single-center, prospective, randomized, controlled, pilot study is to test the hypothesis that inhalation of NO 200 ppm prevents the development of nosocomial pneumonia in patients at risk after cardiac…
- Trial name
- NCT06162455
- Testing
- 200- ppm NO
- Where
- Russia
- Volunteers
- 74 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Ventilator Associated Pneumonia, Multi-antibiotic Resistance
Ventilator Associated Pneumonia by Multi-Drug Resistant Organism
Ventilator-associated pneumonia (VAP) is an infection of the pulmonary parenchyma in patients exposed to invasive mechanical ventilation for at least 48 h and is part of ICU-acquired pneumonia.
- Trial name
- VAP-MDR (NCT05549427)
- Testing
- Ventilation
- Where
- Oman
- Volunteers
- 319 people
- Sponsor
- Sultan Qaboos University
ICU's Patients Under Mechanical Ventilation
Effect of Drainage of Subglottic Secretions on Pneumonia Acquired Under Mechanical Ventilation
The purpose of this study is to determine whether drainage of subglottic secretions is effective to reduce the incidence of pneumonia acquired under mechanical ventilation in ICU's patients.
- Trial name
- NCT00219661
- Testing
- drainage of subglottic secretions (HiLo Evac tube)
- Where
- 4 sites in France
- Volunteers
- 440 people
- Sponsor
- Poissy-Saint Germain Hospital
Pneumonia
Nebulized Colistin for Hospital-Acquired Pneumonia
Nebulized Colistin for Adjunctive Therapy of Hospital-Acquired Pneumonia caused by Gram Negative Bacteria should be more effective than conventional therapy
- Trial name
- NCT00920270
- Testing
- nebulized colistin, antibiotics
- Where
- Thailand
- Volunteers
- 140 people
- Sponsor
- Mahidol University
Ventilator Associated Pneumonia, Bacteremia
Intensive Care Unit Acquired Infections in Patients Colonized With Extended Spectrum Enterobacteriaceae
Worldwide emergence of extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E) had become a major problem in ICU, with at least 10% of incidence at the admission in Europe.
- Conditions
- Ventilator Associated Pneumonia, Bacteremia, Abdominal Infection, Enterobacteriaceae Infections
- Trial name
- BMREA (NCT04903886)
- Testing
- observational
- Where
- France
- Volunteers
- 350 people
- Sponsor
- University Hospital, Brest
Critical Illness, Intensive Care Patients
IMMUNOREA - Immunological and Inflammatory Determinants Associated With the Prognosis of Intensive Care Patients
This is a prospective observational physiopathological study aimed at evaluating the immunological and inflammatory determinants associated with the prognosis of patients admitted to intensive care units (ICU).
- Conditions
- Critical Illness, Intensive Care Patients, Critical Illness Requiring Intensive Care - Sepsis, Critical Illness Requiring Intensive Care - Acute Brain Injury
- Trial name
- IMMUNOREA (NCT07345169)
- Where
- France
- Volunteers
- 540 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Endotracheal Intubation During Surgery, Hospital Acquired Infections
BIP ETT Clinical Tolerability, Safety and Performance Study
The objective of the study is to determine Bactiguard coated BIP Endotracheal tube´s tolerability, safety and performance and compare it to a standard un-coated Endotracheal tube.
- Trial name
- BIPETT (NCT01682486)
- Testing
- BIP ETT (Bactiguard), Standard ETT
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Bactiguard AB
Cross Infection, Clostridium Difficile Infection
Evaluation of the Cost of a Nosocomial Infection With Clostridium Difficile
Clostridium difficile is the first cause of nosocomial infectious diarrhea, due to its mode of transmission and its resistance in the environment.
- Trial name
- NCT03025672
- Volunteers
- 10,445 people
- Sponsor
- Lille Catholic University
Patient With Influenza Like Illness
Effect of Influenza Vaccination of Healthcare Workers (HCW) on the Risk of Influenza in Patients Hospitalized in Short Stays Units
Hospital acquired influenza is associated with significant morbidity and mortality in hospitalized patients notably elderly patients. Vaccination of HCW is recommended to prevent influenza transmission in healthcare setting.
- Trial name
- NCT02198638
- Testing
- A nasal swab
- Where
- 2 sites in France
- Volunteers
- 541 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Airway Clearance Impairment
Comparisons of Two Airway Clearance Techniques
The goal of this clinical trial is to compare the effectiveness of two airway clearance techniques for patients with ventilator associated pneumonia.
- Trial name
- NCT06032871
- Testing
- high frequency chest wall oscillation, Chest physiotherapy
- Where
- 2 sites in Taiwan
- Volunteers
- 30 people
- Sponsor
- Hui-Ling Lin
Early Ventilator Associated Pneumonia, Acute Brain Injuries
PK/PD Target Attainment of Ceftriaxone for the Prevention of Early Ventilator-associated Pneumonia in Neurologically Injured Patients
Critically ill patients admitted for acute brain injury are exposed to many heath-care associated infections such as ventilator associated pneumoniae (VAP).
- Trial name
- NeuroPKVAP (NCT07450404)
- Where
- 2 sites in France
- Volunteers
- 60 people
- Sponsor
- Central Hospital, Nancy, France
Ventilator-Associated Pneumonia
Oropharyngeal Care With Colostrum, Chlorohexidine and Sodium Bicarbonate in Preventing Ventilator-associated Pneumonia in Preterm Neonates
comparing the effect of oral care with colostrum, chlorohexidine and sodium bicarbonate in prevention of ventilator-associated pneumonia in preterm neonates.
- Trial name
- NCT07482007
- Testing
- Oropharyngeal Care with Colostrum, Chlorhexidine Oral Care, Sodium Bicarbonate oral care
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University
Healthcare Associated Infection
Evaluation of Healthcare Waste Management Practices and Problems Among Primary and Secondary Hospitals
Healthcare waste is defined as the total waste stream from a healthcare facility. Most of it (75-90%) is similar waste to domestic waste and is known as healthcare general waste and is made up of paper, plastic packaging, food…
- Trial name
- NCT06739863
- Testing
- healthcare waste management
- Where
- Pakistan
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Superior University
Covid19, Health Care Associated Infection
Incidence of Infection and Mortality by COVID-19 in Specialists
In this current study the researchers aim to identify the total number of infections and deaths due to COVID-19 and distinguish which are the risk factors most related to COVID-19 infections and deaths in medical personnel in…
- Conditions
- Covid19, Health Care Associated Infection, Infection, Coronavirus, Death
- Trial name
- NCT04828148
- Testing
- Survey
- Where
- Mexico
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
Ventilator Associated Pneumonia, Prevention
Nebulized Aztreonam for Prevention of Gram Negative Ventilator-associated Pneumonia
Aerosol antibiotic administration offers the theoretical advantages of achieving high drug concentration at the infection site and low systemic absorption, thereby avoiding toxicity.
- Conditions
- Ventilator Associated Pneumonia, Prevention, Respiratory Infection Other
- Trial name
- AZLIS (NCT03749226)
- Testing
- Aztreonam lysine, Aerogen Solo, CombiHaler
- Where
- Spain
- Volunteers
- 9 people
- Sponsor
- Hospital Universitari Joan XXIII de Tarragona.
Ventilator Associated Pneumonia (VAP), Other Infections
Probiotics: Prevention of Severe Pneumonia and Endotracheal Colonization Trial (PROSPECT): A Feasibility Clinical Trial
Probiotics are commercially available live bacteria thought to have health benefits when ingested. A literature review of probiotic studies in the intensive care unit (ICU) found that in patients who receive probiotics, there is…
- Conditions
- Ventilator Associated Pneumonia (VAP), Other Infections, Antibiotic-Associated Diarrhea, C-Difficile
- Trial name
- PROSPECT (NCT01782755)
- Testing
- L. rhamnosus GG - Probiotic
- Where
- 14 sites in United States, Canada
- Volunteers
- 150 people
- Sponsor
- McMaster University