Clinical trials: Healthcare-Associated Infections
Transplantation Infection
Prevention of Healthcare Associated Infections in Bone Marrow Transplant Patients
This study involves sampling bone marrow transplant patients, hospital workers and the patient room for microbes using swabs and other techniques.
- Trial name
- NCT02463214
- Testing
- Engineered Room
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Ventilator Acquired Pneumonia
Procalcitonin Versus Serum Zinc for Diagnosis of Ventilator-Associated Pneumonia in ICU Patients
Ventilator-associated pneumonia (VAP) is a common and serious infection among mechanically ventilated ICU patients. Early diagnosis remains challenging because clinical and radiological findings may lack specificity.
- Trial name
- PROZINC-VAP (NCT07696897)
- Testing
- Serum Procalcitonin Measurement, Serum Zinc Measurement
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Sohag University
Accuracy, Compliance
Effectiveness of a Multimodal IT Enhanced Hand Hygiene Strategy on Healthcare Associated Infections in Nursing Homes
This study aims to evaluate the effectiveness of a multimodal hand hygiene improvement strategy, enhanced with information technology (IT), in reducing healthcare-associated infections (HAIs) in nursing homes.
- Conditions
- Accuracy, Compliance, Healthcare-associated Infections
- Trial name
- NCT06925620
- Testing
- Multimodal Information Technology-based Hand Hygiene Strategies
- Where
- 2 sites in Taiwan
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Hospital-acquired Pneumonia
0.12% Chlorhexidine Oral Care for the Prevention of Non-ventilator Hospital-acquired Pneumonia
Chlorhexidine is a effective strategy in reducing ventilator associated pneumonia. However, it is unclear if prophylactic 0.12% chlorhexidine oral rinse can reduce the risk of non-ventilator hospital-acquired pneumonia among…
- Trial name
- NCT04403971
- Testing
- 0.12% Chlorhexidine Oral Liquid Product, Listerine Oral Liquid Product, Normal Saline Product
- Where
- Taiwan
- Volunteers
- 103 people
- Sponsor
- National Cheng-Kung University Hospital
Surgical Site Infection
Wound Antiseptic Study With Hypochlorous Acid & Iodopovidone
The purpose of this study is to determine whether hypochlorous acid is an effective antiseptic agent to prevent surgical site infection.
- Trial name
- WASH (NCT00692757)
- Testing
- Hypochlorous acid, Iodopovidone
- Where
- Colombia
- Volunteers
- 432 people
- Sponsor
- Universidad Tecnológica de Pereira
Pneumonia, Ventilator-Associated
The Efficacy of Adjuvant Oral Care in Prevention of Ventilator Associated Pneumonia.
A Randomized Controlled Trial (RCT) at Services Hospital, Lahore, aims to reduce Ventilator-Associated Pneumonia (VAP) incidence and mortality rates while shortening ICU stays in mechanically ventilated patients by adding…
- Trial name
- NCT06039995
- Testing
- Comprehensive Oral Care, Traditional Oral Care, Mechanical Tooth Brushing using 0.2% Chlorhexidine
- Where
- 2 sites in Pakistan
- Volunteers
- 100 people
- Sponsor
- University of Health Sciences Lahore
Ventilator Associated Pneumonia
PREdiction of CEphalosporinase Producing Enterobacteria During Ventilator-associated Pneumonia for Therapeutic Stewardship
Ventilator-associated pneumonia is the leading cause of nosocomial infection in the ICU. Cephalosporinase-producing Enterobacteriaceae have an increasing incidence.
- Trial name
- NCT05486130
- Where
- France
- Volunteers
- 345 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Cross Infection
Reuse of Polyp Traps, a Way to Approach Sustainability
The environmental impact of healthcare practice in the context of climate change is in the spotlight. Digestive endoscopy units are the third hospital unit that generates the most waste and environmental impact.
- Trial name
- POLYPTRAP (NCT06838312)
- Testing
- Reuse or dispose a polyp trap
- Volunteers
- 3,238 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Ventilator Associated Pneumonia
Role of Oral Chlorhexidine Gel in Prevention of Ventilator Associated Pneumonia
The purpose of this study is to determine if oral mucosal application of chlorhexidine gel will prevent the development of ventilator associated pneumonia in children.
- Trial name
- NCT00597688
- Testing
- Chlorhexidine gel
- Where
- India
- Volunteers
- 86 people
- Sponsor
- All India Institute of Medical Sciences
VAP - Ventilator Associated Pneumonia
Effect of Statin Therapy on Mortality in Patients With Ventilator Associated Pneumonia
Statins with their powerful anti-inflammatory, immunomodulatory, and antioxidant properties make them candidate members to be used in the management of sepsis and different types of infections including pneumonia.
- Trial name
- NCT05230472
- Testing
- Simvastatin
- Where
- Egypt
- Volunteers
- 161 people
- Sponsor
- Ain Shams University
Bladder Cancer, Infections
Infectious Complications After Cystectomy: A Prospective Observational Study
Patients undergoing cystectomy for either oncological or non-oncological indications are prospectively enrolled following informed consent.
- Conditions
- Bladder Cancer, Infections, Infection, Bacterial, Infection, Hospital
- Trial name
- NCT05153694
- Testing
- Cystectomy
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Enterobacteriaceae Infections, Hospital-Acquired Infection
Nosocomial Outbreak of BHRe in an Intensive Care Unit During SARS-CoV-2 Pandemic
Multidrug Resistant (MDR) bacteria have become a major worldwide public health challenge and hospitals are now increasingly faced with management of local outbreaks involving such pathogens.
- Trial name
- BHReICU (NCT05055479)
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Ventilator Associated Pneumonia
Chlorhexidine Gluconate Oral Care for Adults Experiencing Trauma
Examine the use of 0.12% Chlorhexidine Gluconate as an adjunct to current oral care protocol for trauma patients on ventilator support to decrease the incidence of Ventilator Associated Pneumonia and oral bacterial load.
- Trial name
- NCT01382446
- Testing
- Chlorhexidine gluconate, Toothpaste
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
Mechanical Ventilation Complication, Ventilator Associated Pneumonia
Effects of Endotracheal Tube Cuff Pressure Control on Microaspiration of Gastric Contents
The purpose of study is to determine effects of three different ET cuff pressure control on microaspiration of the stomach contents.
- Conditions
- Mechanical Ventilation Complication, Ventilator Associated Pneumonia, Nursing Caries, Aspiration, Respiratory
- Trial name
- NCT04061083
- Testing
- Smart Cuff Manager, Manometer
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- Afyonkarahisar Health Sciences University
Infections Associated With Mechanical Ventilation, Pneumonia Associated With Mechanical Ventilation
Efficacy of Mouth-rinse With Chlorhexidine for the Prevention of Ventilator-associated Infections in Intensive Care Unit
Background: Infections associated with mechanical ventilation are associated with high rates of morbidity and mortality, which results not only in an increase in hospitalization days and care costs, but also in an increase in…
- Trial name
- NCT04165356
- Testing
- Mouth-rinse with 0.12% clorhexidine, Mouth-rinse with isotonic solution with 1.5% sodium bicarbonate
- Where
- Mexico
- Volunteers
- 80 people
- Sponsor
- Universidad Autónoma de Yucatán
Ventilator Associated Pneumonia
Single-used Versus MultiPlE-used Endotracheal suCtIon cAtheters in Mechanically ventiLated ICU Patients
In low and middle-income countries, open endotracheal suction catheters are used multiple times to perform suctioning due to limited resources [1,2].
- Trial name
- SPECIAL-ICU (NCT06207513)
- Testing
- Suction Circuit Flushing with Chlorhexidine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Mechanical Ventilation
Endotracheal Tube With Polyurethane Cuff and Subglottic Secretion Drainage
Patients mechanically ventilated using an endotracheal tube with a subglottic secretion drainage lumen and a polyurethane cuff may develop lower ventilator-associated pneumonia than using a conventional endotracheal tube
- Trial name
- A/N (NCT00475579)
- Testing
- tube with subglottic drainage and polyurethane cuff
- Volunteers
- 280 people
- Sponsor
- Hospital Universitario de Canarias
Staphylococcal Infections
Cost-Effectiveness Study Comparing Chlorhexidine Bathing With Active Surveillance Cultures to Prevent Methicillin-resistant Staphylococcus Aureus & Other Hospital Infections
This pilot study in our medical intensive care unit will evaluate the clinical and cost-effectiveness of an active surveillance program for methicillin-resistant Staphylococcus aureus (MRSA), compared to routine daily bathing…
- Trial name
- NCT00779246
- Testing
- Nasal swabs for MRSA culture, Chlorhexidine gluconate, Contact isolation
- Where
- United States
- Volunteers
- 1,518 people
- Sponsor
- Christiana Care Health Services
Ventilator Associated Pneumonia
Inhibition Effects of Probiotics on Pathogens Associated With VAP
This study evaluates that P. aeruginosa, A. baumannii, K. pneumonia and Staph aureus which are obtained from patients' tracheal aspiration culture who treated with mechanical ventilation will be compared with Lactobacillus (LAB)…
- Trial name
- NCT02928042
- Testing
- Lactobacillus bacteria
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Ventilator Associated Pneumonia
Application of VAP Bundle Among ICU Nurses
Background: Ventilator associated pneumonia (VAP) is a recognized healthcare-associated infection in lungs parenchyma that occurs in patients in which they are connected to mechanical ventilator.
- Trial name
- NCT05517759
- Testing
- Educational program
- Where
- Bahrain
- Volunteers
- 58 people
- Sponsor
- University of Bahrain