Clinical trials: Healthy Adult Male
Healthy Volunteer, Muscular Atrophy, Spinal
A Study to Learn About the Safety of BIIB115 Injections and How BIIB115 is Processed in the Bodies of Healthy Adult Male Volunteers and of Pediatric Participants With Spinal Muscular Atrophy Who Previously Took Onasemnogene Abeparvovec
In this study, researchers will learn about a study drug called BIIB115 in healthy adult male volunteers and in participants with spinal muscular atrophy (SMA). This study will focus on children with SMA.
- Trial name
- NCT05575011
- Testing
- BIIB115
- Where
- 16 sites in Belgium, Canada and 7 more
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Biogen
C3 Glomerulopathy, IgA Nephropathy
Study of ARO-C3 in Adult Healthy Volunteers and Patients With Complement Mediated Renal Disease
The purpose of AROC3-1001 is to evaluate the safety, tolerability, pharmacokinetics and/or pharmacodynamics in adult healthy volunteers (HVs) and in adult patients with complement-mediated renal disease (C3 Glomerulopathy [C3G]…
- Trial name
- NCT05083364
- Testing
- ARO-C3
- Where
- 16 sites in Australia, Georgia and 5 more
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Arrowhead Pharmaceuticals
Diabetic Foot
BE STUDY OF METFORMIN GSK 1000mg
A randomized, balanced, open label, crossover, two period, two treatment, two sequence, single dose, oral bioequivalence study under fasting condition.
- Trial name
- BA/BE 199/11 (NCT01710553)
- Testing
- Glucophage 1000mg, Metformin GSK 1000mg
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy
Mass Balance Study of [14C]HSK31858 in Healthy Adult Male Chinese Subjects.
This is a single-center, nonrandomized, and open design study to investigate the pharmacokinetics, mass balance, metabolism and excretion of HSK31858 in healthy male subjects.
- Trial name
- NCT06569784
- Testing
- [14C]HSK31858
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Xizang Haisco Pharmaceutical Co., Ltd
Hyperphosphatemia
Bioequivalence Study of BAY77-1931 Granule
The study is conducted as a randomized, non-blinded, 2-way crossover study. Target population is 60 Japanese healthy male adult subjects selected by screening examination which will be conducted within 4 weeks before the first…
- Trial name
- NCT01053676
- Testing
- Lanthanum Carbonate (Fosrenol, BAY77-1931) Granule, Lanthanum Carbonate (Fosrenol, BAY77-1931) Chewable tablet
- Where
- Japan
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Bayer
Healthy
Cetirizine Hydrochloride Tablets, 10 mg Bioequivalence Study of Dr.Reddy's Under Fed Condition
A Two Way, Open Label, Single Dose, Cross Over, Experimental Evaluation of Relative Bioavailabilities of Two Formulations of Cetirizine Hydrochloride Tablets 10 mg of Dr.
- Trial name
- NCT01064115
- Testing
- Cetirizine Hydrochloride
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Healthy Volunteers, Chronic Kidney Disease
A Study to See How Safe a New Medicine (NNC0705-0001) is in Healthy People
The study is testing a new study medicine (called NNC0705-0001), as a potential medicine to treat chronic systemic inflammation, which is known for increasing the risk of developing cardiometabolic diseases.
- Trial name
- NCT07029568
- Testing
- NNC0705-0001
- Where
- Netherlands
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Healthy Subjects
Single Dose Study To Study The Absorption, Metabolism And Excretion Of Famitinib
The purpose of this study is to evaluate the excretion balance, metabolic profile and the routes of excretion of famitinib in healthy adult male subjects.
- Trial name
- NCT05473468
- Testing
- Famitinib
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Healthy Participants
A Study to Learn How the Medicine Called [14C] PF-06821497 is Taken up Into and Removed From the Body.
The purpose of this study is to learn how a certain amount of [14C] PF-06821497 is taken up into the bloodstream and removed from the body. The study is seeking participants who are: Males aged 18 years or older.
- Trial name
- NCT06392230
- Testing
- Oral [14C] PF-06821497, Oral PF-06821497, IV [14C] PF-06821497
- Where
- Netherlands
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy
A Clinical Study to Determine Biomarkers of Response to a Gamma Secretase Inhibitor
The purpose of this study is to determine the transcriptional signature of Notch Inhibition by testing hair and blood samples on healthy male volunteers who have received MK0752 vs placebo for possible future biomarkers in the…
- Trial name
- NCT00803894
- Testing
- MK0752, Comparator: MK0752.
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Diabetes Mellitus, Type 2
Injection Site Study In Patients With Type 2 Diabetes Mellitus (T2DM) And Healthy Volunteers
This study is an open-label study in healthy volunteers and in patients with Type 2 Diabetes Mellitus to assess safety and tolerability parameters, the levels of GSK716155 in the bloodstream after a single dose given at different…
- Trial name
- NCT00394030
- Testing
- GSK716155 subcutaneous injections
- Where
- 6 sites in United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy Participants
A Study to Understand the Effects of Carbamazepine on How Vepdegestrant is Processed in Healthy Participants
The purpose of this study is to understand if carbamazepine reacts with vepdegestrant and affects how it is processed in the bodies of healthy participants.
- Trial name
- PK (NCT06005688)
- Testing
- Vepdegestrant, Carbamazepine
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Chronic Myeloid Leukemia
TGRX-678 Pharmacokinetic Mass Balance
This is a pharmacokinetic study for [14C]TGRX-678 on mass balance to evaluate distribution, metabolism and excretion of TGRX-678, a tyrosine kinase inhibitor indicated for treatment of chronic myeloid leukemia.
- Trial name
- NCT06986772
- Testing
- [14C]TGRX-678
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Shenzhen TargetRx Co., Ltd.
Gout
RDEA3170 Bioavailability Study
This is a Phase 1, randomized, open-label, 4-way crossover pharmacokinetic (PK) and pharmacodynamic (PD) study in healthy adult male subjects designed to assess the relative bioavailability of RDEA3170 2.5 mg tablets administered…
- Trial name
- NCT02336594
- Testing
- RDEA3170 10 mg, RDEA3170 2.5 mg
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Ardea Biosciences, Inc.
Healthy Volunteers
A Pharmacokinetic And Safety Study Of Voriconazole In Healthy Male And Female Adults
This study is to assess the plasma concentration-time profile of voriconazole in adults receiving 7-day intravenous treatment and 6.5-day oral treatment.
- Trial name
- NCT00855101
- Testing
- voriconazole
- Where
- Belgium
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy
A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of JNJ-39439335 in Healthy Japanese and Caucasian Adult Male Participants
The purpose of this study is to investigate the safety, tolerability, and pharmacokinetics of JNJ-39439335 in healthy Japanese and Caucasian adult male participants in Part 1, and in healthy Japanese adult male participants in…
- Trial name
- NCT01631487
- Testing
- JNJ-39439335 10 mg, JNJ-39439335 25 mg, JNJ-39439335 50 mg
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Healthy
A Drug Interaction Study of Warfarin and Canagliflozin in Healthy Adult Volunteers
The purpose of the study is to assess the effect of multiple oral doses of canagliflozin on a single oral dose of warfarin.
- Trial name
- NCT01195324
- Testing
- Canagliflozin/Warfarin
- Where
- Belgium
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Healthy Adult Subjects
A Drug-drug Interaction Trial to Evaluate the Pharmacokinetics Effect of Rifampicin on Famitinib
The primary objective of the study was to assess the effect of repeated oral doses of Rifampicin on the pharmacokinetic profile of a single dose of Famitinib.
- Trial name
- NCT04494659
- Testing
- Famitinib capsule, Rifampicin capsule
- Where
- China
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Undefined
Single Ascending-dose Study to Evaluate Safety, Tolerability, and PK of MYMD1 in Healthy Male Adult Subjects
Double-blind, placebo-controlled, First-in-Human, single ascending-dose study. Approximately 40 healthy adult male subjects will be given a single capsule of MYMD1 to determine its safety, how well it is tolerated, how the body…
- Trial name
- NCT04349761
- Testing
- MyMD1
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- TNF Pharmaceuticals, Inc.
Healthy Adults
A Study to Understand How the Body Processes [14C]PF-07104091 in Healthy Participants
The purpose of this study is to learn how the body processes the study medicine PF-07104091. The study is seeking participants who are: Healthy male aged 18 to 65 years of age Participants in the study will receive 14C-labeled…
- Trial name
- NCT07127770
- Testing
- PF-07104091
- Where
- Netherlands
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Pfizer