Clinical trials: Healthy Adult Male
Healthy Adult Subjects
A Study On Human Mass Balance And Biotransformation
This study will evaluate the absorption,metabolism and excretion of CBP-307 in healthy chinese male subjects.
- Trial name
- NCT05040113
- Testing
- CBP-307
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Connect Biopharm LLC
Healthy, Pharmacokinetics of Quetiapine
Study to Evaluate the Effect of Multiple-dose of Fluvoxamine on the Plasma Concentration of Quetiapine (FK949E) in Healthy Male Volunteers
The objective of the study was to assess the effect of multiple-dose fluvoxamine on the pharmacokinetics of quetiapine (FK949E) in healthy adult male subjects. The safety of FK949E in the population was also evaluated.
- Trial name
- NCT01908296
- Testing
- FK949E, fluvoxamine
- Where
- Japan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Pain, Acute
Pharmacokinetics and Pharmacodynamics of TRV130, Morphine, and Placebo in Healthy Subjects
This study is designed to compare TRV130 to placebo and morphine to learn about its effects on pain relief and side effects.
- Trial name
- NCT02083315
- Testing
- TRV130 1.5 mg, TRV130 3 mg, TRV130 4.5 mg
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Trevena Inc.
Renal Impairment, Renal Disease
Nitazoxanide Pharmacokinetic Parameters in Renal Impaired Subjects
This study is being conducted to evaluate the major Nitazoxanide (NTZ) active metabolite in adult participants with renal impairment and healthy adults.
- Conditions
- Renal Impairment, Renal Disease, Kidney Disease
- Trial name
- NCT05368935
- Testing
- Nitazoxanide
- Where
- 2 sites in United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Genfit
Healthy Adult Male
OPC-61815 in Healthy Chinese Male Subjects
To evaluate the pharmacokinetic (PK) characteristics and pharmacological effect of OPC-61815 in healthy Chinese Male subjects
- Trial name
- NCT05439148
- Testing
- OPC-61815 injection
- Where
- China
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Otsuka Beijing Research Institute
Healthy Subjects
A Drug Interaction Study to Evaluate the Pharmacokinetics of ASP1517 and Lanthanum Carbonate Hydrate
The objective of this study is to evaluate the effect of lanthanum carbonate hydrate on the pharmacokinetics (PK) of ASP1517 in non-elderly healthy male subjects.
- Trial name
- NCT02952040
- Testing
- ASP1517, Lanthanum carbonate hydrate
- Where
- Japan
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Mass Balance Study
Mass Balance Study of [14C] D-1553 in Chinese Healthy Adult Male Subjects
To quantitatively analyze the total radioactivity (TRA) in excrement after a single oral dose of [14C] D-1553 in healthy subjects, and obtain radioactivity recovery and primary excretion pathways in humans; To obtain radioactive…
- Trial name
- NCT06233916
- Testing
- [14C] D-1553
- Where
- China
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- InventisBio Co., Ltd
Healthy
Bioavailability Study Comparing 2 Vamifeport Oral Formulations in Fasted Versus Fed State in Healthy Subjects
Two different vamifeport oral formulations will be administered in fed and fasted state to assess the vamifeport food-drug interaction and to assess the relative bioavailability (the proportion of drug entering the circulation)…
- Trial name
- NCT05077436
- Testing
- Vamifeport Formulation 1, Vamifeport Formulation 2
- Where
- United Kingdom
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Vifor (International) Inc.
Healthy
Bioequivalence Study of Mycophenolate Mofetil 250 mg Capsule, Under Fasting Conditions
An open-label, balanced, randomized, two-treatment, two-period, two sequence, single dose, crossover, bioequivalence study of Mycophenolate mofetil 250 mg Capsule of Dr.
- Trial name
- NCT01513044
- Testing
- Mycophenolate Mofetil
- Where
- India
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Healthy Adult Male and Female Volunteers
Study to Assess the Bioavailability, Pharmacokinetics, Safety, and Tolerability of AVP-923 in Healthy Adult Participants
This study will be conducted to evaluate the relative bioavailability, pharmacokinetics, safety, and tolerability of AVP-923 (dextromethorphan hydrobromide [DM] and quinidine sulfate [Q] capsules) when the contents of a capsule…
- Trial name
- NCT03381664
- Testing
- AVP-923
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Avanir Pharmaceuticals
Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men, Hot Flashes
A Study to Learn How a Proton Pump Inhibitor Affects the Way Elinzanetant (BAY 3427080) Moves Into, Through and Out of the Body, and How Much of it Gets Absorbed by the Body When Taken as a Single and Small Radioactive Dose in Healthy Adults
Researchers are looking for a better way to treat people who have vasomotor symptoms (VMS). VMS such as hot flashes are caused by hormonal changes occurring during menopausal transition when women may have also changes in their…
- Trial name
- NCT05061563
- Testing
- Elinzanetant (BAY3427080), Esomeprazole
- Where
- Netherlands
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Bayer
Healthy Adult Male Volunteers
ADME Study of [14C]- Rongliflozin in Healthy Male Subjects
Study to Evaluate the Mass Balance and Biotransformation of Single Dose [14C]- Rongliflozin in healthy male subjects.
- Trial name
- NCT05109078
- Testing
- [14C]- Rongliflozin
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Sunshine Lake Pharma Co., Ltd.
Healthy
A Drug-Drug Interaction Study of Omeprazole and PA21
The purpose of this study is to determine if Omeprazole is affected by PA21.
- Trial name
- NCT01452906
- Testing
- PA21 and Omeprazole with food, No PA21; Omeprazole with food, PA21 with food, Omeprazole 2hrs later
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Vifor Pharma
Healthy Volunteers
A Study of the Safety, Tolerability, and Pharmacokinetics of Orally Administered Venglustat and Itraconazole in Healthy Adult Male Participants
The purpose of this study is to assess in healthy adult male participants the effects of itraconazole on the pharmacokinetics of venglustat and to assess the safety and tolerability of venglustat with and without coadministration…
- Trial name
- NCT06421714
- Testing
- Venglustat, Itraconazole
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Genzyme, a Sanofi Company
Healthy
A Study in Healthy People to Test Whether BI 1291583 Influences the Amount of Dabigatran in the Body
The main objective of this trial is to investigate the effect of a single dose of BI 1291583 on the pharmacokinetics of a single dose of dabigatran, an efflux transporter P-glycoprotein (P-gp) substrate.
- Trial name
- NCT06791187
- Testing
- dabigatran etexilate, BI 1291583
- Where
- Germany
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Idiopathic Pulmonary Fibrosis
Safety, Tolerability and Pharmacokinetic Study of LTI-03 in Healthy Adult Subjects
The current study will investigate the initial safety, tolerability, and PK profile of inhaled LTI-03 in healthy volunteers. In order to minimize exposure, the study will first test single ascending doses (SAD) of LTI-03 followed…
- Trial name
- NCT04233814
- Testing
- Caveolin-1-Scaffolding-Protein-Derived Peptide (LTI-03)
- Where
- United Kingdom
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Rein Therapeutics
Healthy Volunteer
The Safety and Pharmacokinetics Study of TAKC-02 Inhalation Solution in Healthy Adult Males.
MEX3B is an RNA-binding protein that is conserved in many animal species and has wide range of biological function. The MEX3B protein is deeply involved in the expression of various cytokines associated with the onset and…
- Trial name
- NCT05018533
- Testing
- TAKC-02
- Where
- Japan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- TAK-Circulator Co.
Healthy
Megavec 400 mg (Imatinib Mesylate) in Healthy Adult Male Volunteers
The purpose of this Study is to Assess Safety and Pharmacokinetics of megavec 400 mg (Imatinib mesylate) under Fasted Conditions in Healthy Male Subjects.
- Trial name
- NCT01653314
- Testing
- Megavec, Glivec
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Daewoong Pharmaceutical Co. LTD.
Healthy Adult Male
Single-ascending Dose Study of HEC-151 Injection
Evaluate the safety, tolerability, PK/PD and immunogenicity characteristics of a single subcutaneous HEC-151 Injection solution in healthy participants
- Trial name
- NCT07376200
- Testing
- HEC-151 Injection, Degludec insulin
- Where
- 2 sites in China
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Sunshine Lake Pharma Co., Ltd.
Bioequivalence, Healthy Subjects
Bioequivalence Study of Test and Reference 400 mg Ibuprofen Coated Tablets in Healthy Volunteers
This study is a comparative bioavailability study performed to assess bioequivalence between Test medicinal product (Darfen 400, 400 mg ibuprofen coated tablets [512 mg ibuprofen sodium dihydrate], manufactured by PrJSC…
- Trial name
- NCT05663398
- Testing
- Darfen 400, 400 mg ibuprofen coated tablets (512 mg ibuprofen sodium dihydrate), Nurofen® Forte Express, 400 mg ibuprofen coated tablets (512 mg ibuprofen sodium dihydrate)
- Where
- Jordan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Darnitsa Pharmaceutical Company