Clinical trials: Healthy Adult Male
Obesity&T2D
Bioequivalence Study of GZR18 Injection Before and After CMC Change
This is an open-label, randomized, single-dose, parallel comparison bioequivalence study conducted in healthy adult male subjects.
- Trial name
- NCT07355738
- Testing
- GZR18 injection A, GZR18 injection B
- Where
- China
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Gan & Lee Pharmaceuticals.
Healthy Adult Male Volunteers
ADME Study of [14C]- Rongliflozin in Healthy Male Subjects
Study to Evaluate the Mass Balance and Biotransformation of Single Dose [14C]- Rongliflozin in healthy male subjects.
- Trial name
- NCT05109078
- Testing
- [14C]- Rongliflozin
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Sunshine Lake Pharma Co., Ltd.
Healthy Volunteers
A Study of the Safety, Tolerability, and Pharmacokinetics of Orally Administered Venglustat and Itraconazole in Healthy Adult Male Participants
The purpose of this study is to assess in healthy adult male participants the effects of itraconazole on the pharmacokinetics of venglustat and to assess the safety and tolerability of venglustat with and without coadministration…
- Trial name
- NCT06421714
- Testing
- Venglustat, Itraconazole
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Genzyme, a Sanofi Company
Drug Interaction Potentiation
A Drug-Drug Interaction Study of Digoxin and PA21
The purpose of this study is to determine if Digoxin is affected by PA21.
- Trial name
- NCT01477411
- Testing
- PA21, Digoxin
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Vifor Pharma
Moderate-to-severe Benign Prostatic Hyperplasia (BPH)
Bioequivalence Study of AJU-G721 and G721R in Healthy Adult Volunteers Under Fed Conditions
To evaluate and compare the safety and pharmacokinetic profiles of "AJU-G721" (test drug) and "G721R" (reference drug) in healthy adult male subjects.
- Trial name
- NCT07643233
- Testing
- Test Drug, Reference Drug
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- AJU Pharm Co., Ltd.
Respiratory Viral Infection
Study to Evaluate the Pharmacokinetics and Relative Bioavailability of Metabolites in Healthy Chinese Adult Males
Study to evaluate the pharmacokinetics and relative bioavailability of metabolites in healthy Chinese adult males
- Trial name
- NCT06841926
- Testing
- ZX-7101A dry suspension, ZX-7101A tablet
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nanjing Zenshine Pharmaceuticals
Healthy
Bioequivalence Study of Mycophenolate Mofetil 250 mg Capsule, Under Fasting Conditions
An open-label, balanced, randomized, two-treatment, two-period, two sequence, single dose, crossover, bioequivalence study of Mycophenolate mofetil 250 mg Capsule of Dr.
- Trial name
- NCT01513044
- Testing
- Mycophenolate Mofetil
- Where
- India
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Healthy
A Drug-Drug Interaction Study of Omeprazole and PA21
The purpose of this study is to determine if Omeprazole is affected by PA21.
- Trial name
- NCT01452906
- Testing
- PA21 and Omeprazole with food, No PA21; Omeprazole with food, PA21 with food, Omeprazole 2hrs later
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Vifor Pharma
Healthy
Bioequivalence Study of Torrent Pharmaceutical Limited's Isosorbide Mononitrate 120 mg ER Tablets Under Fed Conditions
Objective: to compare the single dose bioavailability of Torrent's Isosorbide Mononitrate 120 mg ER Tablets (Test) and Isosorbide Mononitrate 120 mg ER Tablets (Reference) of Kremers Urban, USA under fed condition.
- Trial name
- NCT01418547
- Testing
- Torrent's Isosorbide Mononitrate 120 mg ER Tablets
- Where
- 2 sites in India
- Volunteers
- healthy volunteers welcome
- Sponsor
- Torrent Pharmaceuticals Limited
Japanese Healthy Adult Males
Drug-Drug Interaction Study Between TAK-272 and Itraconazole, Digoxin or Midazolam
The purpose of this study is to evaluate the effect of repeated-dose administration of itraconazole on the pharmacokinetics of TAK-272, as well as the effect of repeated-dose administration of TAK-272 on the pharmacokinetics of…
- Trial name
- NCT02370615
- Testing
- TAK-272, Digoxin, Itraconazole
- Where
- Japan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Takeda
Diarrhea
ACH04 to Assess the Safety and Tolerability in Healthy Adults Subjects
This study intends to provide information on the safety and tolerability of repeated oral doses of ACH04. A phase I, single-center, first in human, open-label, dose escalation study of ACH04 to assess the safety and tolerability…
- Trial name
- NCT02949089
- Testing
- ACH04
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ache Laboratorios Farmaceuticos S.A.
Cognition Disorders
This is a Single Ascending Dose Tolerance Study
This is a single rising dose tolerance (Part A) followed by a functional magnetic resonance imaging (Part B)
- Trial name
- NCT01133574
- Testing
- SLV354 capsules
- Where
- United Kingdom
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Abbott
Creatine Absorption in Healthy Adults
Impact of OptiCreatine on Plasma Creatine and Gastrointestinal Effects in Males and Females
The study aims to evaluate the novel OptiCreatine formulation, which combines creatine with other bioactive compounds purported to enhance absorption and reduce gastrointestinal (GI) discomfort.
- Trial name
- NCT07225335
- Testing
- OptiCreatine, Creatine Monohydrate
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- TSI Group LTD
Healthy Adult, Prostate Cancer
The Dosimetry, Safety and Diagnostic Efficacy of ⁶⁸Ga-FC516 in Healthy Subjects and Patients With Prostate Cancer
This goal of this study is to investigate the dosimetry, safety, biodistribution of ⁶⁸Ga-FC516. In this study, we will evaluate the safety, biodistribution and dosimetry of ⁶⁸Ga-FC516 in subjects and compared them with the…
- Trial name
- NCT07468708
- Testing
- ⁶⁸Ga-FC516, ⁶⁸Ga-FC516 and ⁶⁸Ga-labeled prostate cancer-targeting tracer
- Where
- China
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- FindCure Biosciences (ZhongShan) Co., Ltd.
Healthy Volunteer
Human Mass Balance and Biotransformation Study of [14C]Afuresertib
This study adopts a single-center, single-dose, non-randomized, open-label design with a proposed enrollment of 6-10 healthy male subjects.
- Trial name
- NCT05489744
- Testing
- [14C]Afuresertib
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Laekna Limited
Hashimoto Disease
Single Ascending and Multiple Dose Study to Evaluate Safety, Tolerability, and PK of MYMD1 in Healthy Male and Female Adult Subjects
Double-blind, placebo-controlled, single ascending and multiple dose study. Approximately 32 healthy adult male and female subjects will be given a single capsule of MYMD1 to determine its safety, tolerability, and…
- Trial name
- NCT05077865
- Testing
- MYMD-1
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- TNF Pharmaceuticals, Inc.
Gastroesophageal Reflux Disease
Mass Balance Study of [14C]X842 in Healthy Adult Male Subjects
This study is a single-site, single-dose, non-randomized, open-label study to assess the absorption, metabolism, and excretion profile of [14C]X842 in healthy adult male subjects.
- Trial name
- NCT07107672
- Testing
- [14C]X842
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Jiangsu Sinorda Biomedicine Co., Ltd
Healthy Male Volunteer
A Study of the Safety and Pharmacokinetics of JNJ-38518168 in Japanese and Caucasian Male Participants and the Effect of JNJ-38518168 on the Blood Levels of Midazolam
The purpose of Part 1 of this study is to evaluate the safety, tolerability, and pharmacokinetics ("PK", how the drug is absorbed in the body, distributed within the body, and how it is removed from the body over time) of…
- Trial name
- NCT01442532
- Testing
- JNJ-38518168 (30 mg), JNJ-38518168 (10 mg), JNJ-38518168 (3 mg)
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Chronic Kidney Disease
A Study to Learn More About How Safe Nurandociguat is and How it Affects the Way the Body Processes Rosuvastatin and Dabigatran in Healthy Adults
Researchers are looking for a better way to treat people who have chronic kidney disease. Chronic kidney disease (CKD) is a long-term condition where the kidneys do not work as well as they should.
- Trial name
- NCT07515339
- Testing
- Nurandociguat, Rosuvastatin, Dabigatran etexilate
- Where
- Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bayer
Normal Healthy Volunteers
Safety, Tolerability, and Pharmacokinetics of Oral BT-11 in Healthy Adult Male and Female Volunteers
Study type: Interventional Description of intervention(s) / exposure For single ascending dose, five dose target ranges of BT-11 (depending on body weight the doses in each cohort will be 5.9 - 7.7 mg/kg; 18.9 - 25.0 mg/kg; 44.3…
- Trial name
- NCT03860571
- Testing
- BT-11
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- NImmune Biopharma