Clinical trials: Healthy Adult Subjects
Typhoid
Immunogenicity, Safety and Tolerability of the Typhoid Fever Vaccine Candidate M01ZH09 in Healthy Adults
This study is to investigate the safety, tolerability and immunogenicity of the typhoid fever vaccine candidate M01ZH09 manufactured at commercial scale, at a new manufacturing facility.
- Trial name
- NCT00679172
- Testing
- Dose of 5.0 x 10^9 CFU (Cohort 1), Dose of 7.5 x 10^9 CFU (Cohort 2), Dose of 1.1 x 10^10 CFU (Cohort 3)
- Where
- 3 sites in United States
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Emergent BioSolutions
Type2 Diabetes Mellitus
A Study to Evaluate the Safety and Pharmacokinetics of Dapagliflozin, Linagliptin, and Metformin in Healthy Adults: Fed State Study
To Evaluate the Safety and Pharmacokinetics of Dapagliflozin, Linagliptin, and Metformin in Healthy Adults after taking the drugs with food (fed state).
- Trial name
- NCT07044765
- Testing
- Comparator 1, Comparator 2, Test Drug
- Where
- South Korea
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- AJU Pharm Co., Ltd.
Healthy Adult Subjects
A Crossover Study to Evaluate Pegilodecakin (LY3500518) in Healthy Participants
The purpose of this study is to assess how fast pegilodecakin gets into the blood stream and how long it takes the body to remove it, when given as a solution formulation via a prefilled syringe (PFS) versus from a vial drawn…
- Trial name
- Willow 3 (NCT04194892)
- Testing
- Pegilodecakin
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Healthy
Pharmacokinetic Study of SP-103 in Healthy Adult Human Subjects
This study will assess the systemic exposure and pharmacokinetic parameters of SP-103 topical system following one, two, or three topical system applications and compare to the pharmacokinetics of ZTlido.
- Trial name
- NCT04819581
- Testing
- SP-103, ZTlido
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Scilex Pharmaceuticals, Inc.
Cicatrix, Scar Prevention
A Study of Single Ascending Dose of LEM-S401 in Healthy Participants
The primary objective of the study is to assess the safety and tolerability of single dose of LEM-S401 in healthy adult subjects.
- Trial name
- NCT04707131
- Testing
- LEM-S401
- Where
- South Korea
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Lemonex Inc.
Healthy
Single Dose Study To Compare Pharmacokinietics Of 3 Different Formulations Of PF-04991532 In Healthy Volunteers
The primary purpose of this study is to evaluate the pharmacokinetics, safety and tolerability three different formulations of PF-04991532 in healthy adult subjects.
- Trial name
- NCT01351129
- Testing
- Formulation 1, Formulation 2, Formulation 3
- Where
- Singapore
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Influenza, Orthomyxoviruses
Immunogenicity of a Split, Cell-Based, Inactivated, Trivalent Influenza Vaccine in Healthy Adult Subjects
Primary Objective: To describe the immune response to a single administration of 2 formulations of the investigational cell-based influenza vaccines in healthy adult subjects.
- Conditions
- Influenza, Orthomyxoviruses, Myxovirus Infection
- Trial name
- NCT00845429
- Testing
- Influenza virus vaccine - cell based (2007-2008 Formulation), Influenza virus vaccine - cell-based (2007-2008 Formulation), Influenza virus vaccine (2007-2008 Formulation)
- Where
- 15 sites in United States
- Volunteers
- 729 people, healthy volunteers welcome
- Sponsor
- Sanofi
Healthy Adult Subject
A Study To Characterize Mass Balance Of [14C] HDM1002 in Chinese Healthy Subjects
In this study, a single dose of [14C] radiolabelled HDM1002 will be administered orally. The main purpose of this study is to find out how much of HDM1002 and its metabolites pass from blood into urine and feces, and characterize…
- Trial name
- NCT06576401
- Testing
- [14C] HDM1002
- Where
- China
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.
Parkinson's Disease (PD)
Relative Bioavailability Study of HNC364 Injectable Suspension
HNC364 is a new pro-drug of rasagiline as a long-acting injection for deep IM deltoid injection, for the treatment of Parkinson"s disease (PD).
- Trial name
- NCT06798519
- Testing
- HNC364 Injectable Suspension, Rasagiline Tablets
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Guangzhou Henovcom Bioscience Co. Ltd.
Healthy
A Crossover Study to Assess the Effect of Intravenous Infusion of Piperacillin/Tazobactam on the Pharmacokinetics of Orally Administered Lumicitabine (JNJ-64041575) in Healthy Adult Participants
The main purpose of this study is to evaluate the effect of intravenous (IV) infusions of piperacillin/tazobactam on the pharmacokinetics (PK) of JNJ-63549109 after a single oral dose of lumicitabine in healthy adult participants.
- Trial name
- NCT03441529
- Testing
- Lumicitabine, Piperacillin/Tazobactam
- Where
- Belgium
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Healthy Volunteers
A Trial to Compare the Amount of Centanafadine That Enters the Bloodstream for Two Different Formulations of Centanafadine
The purpose of this trial is to assess relative bioavailability of centanafadine (CTN) SR tablet to CTN QD XR capsule in healthy adult participants.
- Trial name
- NCT07465731
- Testing
- Centanafadine SR, Centanafadine QD XR
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Healthy
PK, PD, Safety and Immunogenicity Study of Erythropoietin of Incepta Pharmaceuticals Ltd With Eprex (Janssen-Cilag).
Erythropoietin is a glycoprotein which stimulates red blood cell production. It is produced in the kidney and stimulates the division and differentiation of committed erythroid progenitors in the bone marrow.
- Trial name
- NCT07025681
- Testing
- Erythropoietin alfa
- Where
- Bangladesh
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Incepta Pharmaceuticals Ltd
Healthy Volunteer
Drug-drug Interaction Study of Ozanimod With Tyramine to Evaluate the Effect on Pressor Response
The purpose of this study is to evaluate the potential effect of ozanimod on pressor response when co-administered with oral tyramine in healthy adult subjects.
- Trial name
- NCT03694119
- Testing
- Phenelzine, Tyramine, ozanimod
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Celgene
Healthy
Pharmacokinetic Interaction and Safety Between NVP-1203-R1 and NVP-1203-R2
The purpose of this study is to compare the pharmacokinetics and safety between NVP-1203-R1 and NVP-1203-R2
- Trial name
- Navipharm (NCT04181437)
- Testing
- NVP-1203-R1, NVP-1203-R2, NVP-1203-R1 and NVP-1203-R2
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- NVP Healthcare
GERD
Clinical Trial to Assess the PK/PD of YYD601 20mg After Oral Administration if Healthy Adult Subjects (Phase1)
Clinical Trial to Assess the PK/PD of YYD601 20mg After Oral Administration if Healthy Adult Subjects (Phase1)
- Trial name
- NCT03985319
- Testing
- YYD601 20mg, Nexium tab 20mg
- Where
- South Korea
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Yooyoung Pharmaceutical Co., Ltd.
Healthy Volunteers
Study to Determine the Pharmacokinetic (PK) Bioequivalence of ABP 501 and Adalimumab (Humira®) in Healthy Adult Japanese Participants
The primary objective of this study is to determine the bioequivalence of ABP 501 (subcutaneous [SC] injection) compared to adalimumab (SC injection) as assessed principally by the area under the serum concentration-time curve…
- Trial name
- NCT05995691
- Testing
- ABP 501, Adalimumab
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Amgen
Healthy Adult Subjects
Single Ascending Oral Dose Phase 1 Study of ID110521156 in Healthy Adult Subjects
The purpose of this study is to evaluate the safety, tolerability and pharmacokinetics of single oral doses of ID110521156 in healthy adult subjects. This is the first clinical study of ID110521156.
- Trial name
- NCT06063291
- Testing
- ID110521156
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- IlDong Pharmaceutical Co Ltd
IBD (Inflammatory Bowel Disease)
A Phase I Study of INT-210 Capsules in Healthy Adult Subjects (INT-210-I101)
A Phase Ⅰ, Single and Multiple Ascending Dose escalation, and Food-Effect Study of the Safety, Tolerability and Pharmacokinetics of INT-210 Capsules in Healthy Adult Voluteers.
- Trial name
- INT-210-I101 (NCT07616791)
- Testing
- INT-210 Capsule
- Where
- China
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Innatus Therapeutics (Shanghai) Co., Ltd.
Covid19
Study of DS-5670a (COVID-19 Vaccine) in Japanese Healthy Adults and Elderly Subjects
This study will assess the safety, tolerability and immunogenicity of DS-5670a (COVID-19 Vaccine) and determine the recommended dose in Japanese healthy adults and elderly participants.
- Trial name
- NCT04821674
- Testing
- DS-5670a
- Where
- Japan
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Daiichi Sankyo Co., Ltd.
Obesity, Overweight
A Multiple Dose Study Of PF-04620110 In Overweight And Obese, Otherwise Healthy Volunteers
PF-04620110 is a novel compound proposed for the treatment of Type 2 diabetes mellitus. The primary purpose of this trial is to evaluate the safety and tolerability, pharmacokinetics, and pharmacodynamics, of multiple oral doses…
- Conditions
- Obesity, Overweight, Healthy
- Trial name
- NCT00959426
- Testing
- PF-04620110
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Pfizer